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Coccidioides immitis RMSCC 2394 (cimm2)
Gene : CIRG_02140
DDBJ      :             
Swiss-Prot:ACEA_COCIM   RecName: Full=Isocitrate lyase;         Short=ICL;         Short=Isocitratase;         Short=Isocitrase;         EC=4.1.3.1;

Homologs  Archaea  18/68 : Bacteria  406/915 : Eukaryota  119/199 : Viruses  0/175   --->[See Alignment]
c.1.12
:538 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   18->521 1dquA PDBj 0.0 85.5 %
:RPS:PDB   18->521 1dquA PDBj 7e-98 82.7 %
:RPS:SCOP  18->521 1dquA  c.1.12.7 * 0.0 82.7 %
:HMM:SCOP  3->521 1dquA_ c.1.12.7 * 1.6e-187 46.4 %
:RPS:PFM   93->268 PF00463 * ICL 2e-49 58.8 %
:HMM:PFM   15->537 PF00463 * ICL 5.9e-292 72.3 523/526  
:BLT:SWISS 1->538 ACEA_COCIM 0.0 99.8 %
:PROS 205->210|PS00161|ISOCITRATE_LYASE
:SEG

SeqInfo AminoSeq See neighboring genes
Abbreviations Back to title page
GT:ID CIRT_02143 GT:GENE CIRG_02140 GT:PRODUCT GT:DATABASE Broad_Institute GT:ORG cimm2 LENGTH 538 SQ:AASEQ MSLSVEQEEQKYWEEVEAVKQWWKDSRWRYTKRPFTAEQIVAKRGNLKIEYPSNVQSKKLWKLVEEKFKTKTASFTYGCLDPTMVTQMVKYLDTVYVSGWQSSSTASSTDEPSPDLADYPMNTVPNKVNQLWMAQLFHDRKQREERLRNPKEKRASLANIDYLAPIIADADTGHGGLTAVMKLTKLFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPISEHINRLVAIRAQADIMGTDLLAIARTDSEAATLITSTIDPRDHAFVVGSTNPNLEPLNDLMIAAERAGKNGAELQAIEDSWAAKAGLKRFEDAVIDQIKASSAANKQAAIDAFLREIKGKSNKEARAIARQILGTDIFWDWDAPRTREGYYRYQGGCQCAINRAVAFAPFADLIWMESKLPDYAQAKEFAEGVHAVWPQQKLAYNLSPSFNWKAAMPRDEQETYIRRLGELGYCWQFITLAGLHTTALISDQFAKAYAKQGMRAYGELVQEPEMENKVDVVTHQKWSGANYVDELLKMVTGGVSSTSAMGKGVTEDQFK SW:ID ACEA_COCIM SW:DE RecName: Full=Isocitrate lyase; Short=ICL; Short=Isocitratase; Short=Isocitrase; EC=4.1.3.1; SW:GN Name=ICL1; ORFNames=CIMG_01988; SW:KW Complete proteome; Glyoxylate bypass; Lyase; Peroxisome;Tricarboxylic acid cycle. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->538|ACEA_COCIM|0.0|99.8|538/538| GO:SWS:NREP 4 GO:SWS GO:0006097|"GO:glyoxylate cycle"|Glyoxylate bypass| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| GO:SWS GO:0005777|"GO:peroxisome"|Peroxisome| GO:SWS GO:0006099|"GO:tricarboxylic acid cycle"|Tricarboxylic acid cycle| PROS 205->210|PS00161|ISOCITRATE_LYASE|PDOC00145| SEG 5->17|veqeeqkyweeve| SEG 102->115|ssstasstdepspd| BL:PDB:NREP 1 BL:PDB:REP 18->521|1dquA|0.0|85.5|498/513| RP:PDB:NREP 1 RP:PDB:REP 18->521|1dquA|7e-98|82.7|498/513| RP:PFM:NREP 1 RP:PFM:REP 93->268|PF00463|2e-49|58.8|170/176|ICL| HM:PFM:NREP 1 HM:PFM:REP 15->537|PF00463|5.9e-292|72.3|523/526|ICL| GO:PFM:NREP 2 GO:PFM GO:0003824|"GO:catalytic activity"|PF00463|IPR000918| GO:PFM GO:0008152|"GO:metabolic process"|PF00463|IPR000918| RP:SCP:NREP 1 RP:SCP:REP 18->521|1dquA|0.0|82.7|498/513|c.1.12.7| HM:SCP:REP 3->521|1dquA_|1.6e-187|46.4|517/0|c.1.12.7|1/1|Phosphoenolpyruvate/pyruvate domain| OP:NHOMO 850 OP:NHOMOORG 543 OP:PATTERN -------111111111-11---------1-12------------------------------11--11 -11----111111112222-2211223233322222111111-------11-111111----1-1111111-----------2----------------1-1----------------------------------11111---11--1-----------1------11-1------------11111---21111111111111111111221-11111112-1------1-----------------------------------------------------------------------------------------------------------------------1------------------------1111-----111111111111111111111112---------211-111111111111---112-1----1----------211-1-1------------------------------11111-154213334332222222212222124342223-144211111112122111--1-11---------1111---------------------1--222211--1-----------1--------------11-11-112221333323111132111232----121------211111-2222222222-22122222222222212221111111111111111111111111-111111--111111111111---1111111111-1211---------------22222221211-11111111211111111----------111211111111111211111-------1---------------------------------------------------1---1-- ----11------11243344454656722322222222222222224334335531222333211221112211222122211111---45333321111223212-111------------------------------------------------1------------221-121-----1142543321221111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 520 STR:RPRED 96.7 SQ:SECSTR #################HHHHHHTcGGGGGccccccHHHHHHHccccccccTHHHHHHHHHHHHHHHHHHTccEEEEccccHHHHHHHHHHcccEEEcHHHHHHHccTTcccccccccccTTHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHHTTcccccccccEEEEcTTccccHHHHHHHHHHHHHTTccEEEEccccTTccTccccccEEEccHHHHHHHHHHHHHHHHHTTcccEEEEEccGGGEEEEccTTcGGGGGGEEEEccTTcccHHHHHHHHHHcccccHHHHHHHHHHHHHccEEccHHHHHHHHHTcccccHHHHHHHHHHHHTTccHHHHHHHHHHHHcccccccTTccccTTccEEEcccHHHHHHHHHHHTTcccEEEcccccccHHHHHHHHHHHHHHcTTcEEEEEccccccGGGTccHHHHHcHHHHHHHHTEEEEEETTHHHHHHHHHHHHHHHHHHHHTHHHHHHHTHHHHHHHTcGGGcHHHHHTHHHHHHHHHHHHcccccccccTTcHHHHHc# DISOP:02AL 538-539| PSIPRED ccccHHHHHHHHHHHHHHHHHHHcccHHHcccccccHHHHHHHcccccccccHHHHHHHHHHHHHHHHcccccEEEcccccHHHHHHHHHHccEEEEcHHHHHHHcccccccccccccccHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHccccccccccEEEEEccccccHHHHHHHHHHHHHccccEEEEEcccccccccccccccEEEcHHHHHHHHHHHHHHHHHccccEEEEEEEccccccccHHHHHHHHHHHHHcccccccccHHHHHHHHHHccccccHHHHHHHHcccccccHHHHHHHHHHHHHcccccHHHHHHHHHHHcccccHHHHHHHHHHHccccccccccccccccccEEEcccHHHHHHHHHHccccccEEEcccccccHHHHHHHHHHHHHHcccccccccccccccccccccHHHHHHHHHHHHHccccEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccEEEccHHcccHHHHHHHHHHcccHHHHHHHcccccHHHHc //