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Coccidioides immitis RMSCC 2394 (cimm2)
Gene : CIRG_02913
DDBJ      :             
Swiss-Prot:KU70_COCIM   RecName: Full=ATP-dependent DNA helicase II subunit 1;         EC=3.6.1.-;AltName: Full=ATP-dependent DNA helicase II subunit Ku70;

Homologs  Archaea  0/68 : Bacteria  0/915 : Eukaryota  174/199 : Viruses  0/175   --->[See Alignment]
a.140.2b.131.1c.62.1
:647 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   28->229,362->644 1jeqA PDBj 6e-39 39.5 %
:RPS:PDB   125->232 3brjB PDBj 9e-04 18.3 %
:RPS:PDB   602->645 2do1A PDBj 9e-08 29.5 %
:RPS:SCOP  28->238 1jeqB2  c.62.1.4 * 5e-09 18.4 %
:RPS:SCOP  273->555 1jeqA3  b.131.1.1 * 7e-50 33.7 %
:RPS:SCOP  599->644 1jeqA1  a.140.2.1 * 3e-11 34.8 %
:HMM:SCOP  28->272 1jeyA2 c.62.1.3 * 1.5e-58 37.6 %
:HMM:SCOP  274->559 1jeyA1 b.131.1.1 * 2.3e-85 37.7 %
:HMM:SCOP  596->646 1jeqA1 a.140.2.1 * 2.3e-10 45.1 %
:RPS:PFM   32->243 PF03731 * Ku_N 8e-37 48.7 %
:RPS:PFM   316->469 PF02735 * Ku 2e-27 41.6 %
:RPS:PFM   495->552 PF03730 * Ku_C 1e-15 72.4 %
:RPS:PFM   610->643 PF02037 * SAP 2e-04 52.9 %
:HMM:PFM   282->471 PF02735 * Ku 3.7e-38 29.5 183/201  
:HMM:PFM   30->239 PF03731 * Ku_N 2.2e-34 30.0 190/219  
:HMM:PFM   497->556 PF03730 * Ku_C 1.4e-16 38.3 60/95  
:HMM:PFM   610->644 PF02037 * SAP 4.8e-11 48.6 35/35  
:BLT:SWISS 1->613 KU70_COCIM 0.0 99.7 %
:SEG

SeqInfo AminoSeq See neighboring genes
Abbreviations Back to title page
GT:ID CIRT_02916 GT:GENE CIRG_02913 GT:PRODUCT GT:DATABASE Broad_Institute GT:ORG cimm2 LENGTH 647 SQ:AASEQ MAESEYNREDDSFEEEEEVDDSGYKSVKDAVLFAIEVSESMLTAAPNPTSKKARPESPATAALKCAYHLMQQRIISNPKDMIGVLLYGTESSKFYDDDEDGRGSLPYPHCYLFTDLDVPAASDVKELRALVEDEDRAAEILVPSKEPVSMANVLFCANQIFTTKAPNFSSRRLFIVTDNDNPHSKDKVLKSAATVRAKDLYDLGVVIELFPISTPDHDFDTSKFYDDMIYRASPTDPEAPNYSCTSTKTSGADGISILNSLLSSINSKSVPRRALFSNLPLELGPEFRISVSGFLIFKRQAPARSCYVWLGGEQPQIVKGVTTLVADDSAREVEKWEIRKAYKFGGEHVAFTQEEQSALRNFGDPVIRIIGFKPMSSLPIWASTKHSTFIYPSEAGFVGSTRVFSALQQTLLKQKKFALVWFVARKNAAPVMAALIPGEEKLDDNDAQVIPPGMWIQPLPFADDIRQNPETHNIVAPEPLIDKMREIIQVLQLPKGRYDPQRYPNPSLQWHYRILQALALDEDLPDQAEDKTIPKYKQIDKRAGEHVLEWGEELETQNRLLENSKPITSTLAKRPAPSRKAEGDERATKRVRAESTGDAEVKMHYEKGSLNKLTVTILKDFLLSHNLSGTGKKADLIDRVEEFFDRK SW:ID KU70_COCIM SW:DE RecName: Full=ATP-dependent DNA helicase II subunit 1; EC=3.6.1.-;AltName: Full=ATP-dependent DNA helicase II subunit Ku70; SW:GN Name=KU70; ORFNames=CIMG_06138; SW:KW ATP-binding; Chromosomal protein; Complete proteome; DNA damage;DNA recombination; DNA repair; DNA-binding; Helicase; Hydrolase;Nucleotide-binding; Nucleus; Telomere. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->613|KU70_COCIM|0.0|99.7|613/613| GO:SWS:NREP 11 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005694|"GO:chromosome"|Chromosomal protein| GO:SWS GO:0006974|"GO:response to DNA damage stimulus"|DNA damage| GO:SWS GO:0006310|"GO:DNA recombination"|DNA recombination| GO:SWS GO:0006281|"GO:DNA repair"|DNA repair| GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0004386|"GO:helicase activity"|Helicase| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0005634|"GO:nucleus"|Nucleus| GO:SWS GO:0000781|"GO:chromosome, telomeric region"|Telomere| SEG 9->21|eddsfeeeeevdd| SEG 255->267|isilnsllssins| BL:PDB:NREP 1 BL:PDB:REP 28->229,362->644|1jeqA|6e-39|39.5|434/548| RP:PDB:NREP 2 RP:PDB:REP 125->232|3brjB|9e-04|18.3|93/167| RP:PDB:REP 602->645|2do1A|9e-08|29.5|44/55| RP:PFM:NREP 4 RP:PFM:REP 32->243|PF03731|8e-37|48.7|197/213|Ku_N| RP:PFM:REP 316->469|PF02735|2e-27|41.6|149/196|Ku| RP:PFM:REP 495->552|PF03730|1e-15|72.4|58/90|Ku_C| RP:PFM:REP 610->643|PF02037|2e-04|52.9|34/35|SAP| HM:PFM:NREP 4 HM:PFM:REP 282->471|PF02735|3.7e-38|29.5|183/201|Ku| HM:PFM:REP 30->239|PF03731|2.2e-34|30.0|190/219|Ku_N| HM:PFM:REP 497->556|PF03730|1.4e-16|38.3|60/95|Ku_C| HM:PFM:REP 610->644|PF02037|4.8e-11|48.6|35/35|SAP| GO:PFM:NREP 8 GO:PFM GO:0003677|"GO:DNA binding"|PF02735|IPR006164| GO:PFM GO:0004003|"GO:ATP-dependent DNA helicase activity"|PF02735|IPR006164| GO:PFM GO:0006303|"GO:double-strand break repair via nonhomologous end joining"|PF02735|IPR006164| GO:PFM GO:0003677|"GO:DNA binding"|PF03730|IPR005160| GO:PFM GO:0004003|"GO:ATP-dependent DNA helicase activity"|PF03730|IPR005160| GO:PFM GO:0005634|"GO:nucleus"|PF03730|IPR005160| GO:PFM GO:0006303|"GO:double-strand break repair via nonhomologous end joining"|PF03730|IPR005160| GO:PFM GO:0003676|"GO:nucleic acid binding"|PF02037|IPR003034| RP:SCP:NREP 3 RP:SCP:REP 28->238|1jeqB2|5e-09|18.4|185/222|c.62.1.4| RP:SCP:REP 273->555|1jeqA3|7e-50|33.7|273/285|b.131.1.1| RP:SCP:REP 599->644|1jeqA1|3e-11|34.8|46/51|a.140.2.1| HM:SCP:REP 28->272|1jeyA2|1.5e-58|37.6|218/0|c.62.1.3|1/1|vWA-like| HM:SCP:REP 274->559|1jeyA1|2.3e-85|37.7|281/281|b.131.1.1|1/1|SPOC domain-like| HM:SCP:REP 596->646|1jeqA1|2.3e-10|45.1|51/51|a.140.2.1|1/1|SAP domain| OP:NHOMO 229 OP:NHOMOORG 174 OP:PATTERN -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----211-1-1-1111112111111-1111111111111111111111111111111111121111111-11111111111111-111-11111111111121111-1-122111211111111121418K2-229111111111111-11111-21111311111111----11-11--1111111311121-1111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 439 STR:RPRED 67.9 SQ:SECSTR ###########################cEEEEEEEEcccGGGc######ccccccccHHHHHHHHHHHHHHHHHHTTcccEEEEEEEcccccc#########cTTccccEEEEEEEEcccHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHTccccccEEEHcccccHHHHHHHHHHHcTTHHHHHHHHHHTTccHHHHHHHHHHHccccccTTcHHHHHH#################################################################################################################################ccccEEEEEEEEEGGGccTTccccccEEEEEcTTTcTTHHHHHHHHHHHHHHHTEEEEEEEEcccccccEEEEEEEEccEEcTTccEEEccEEEEEEcccGGGcccccccccccccHHHHHHHHHHHHHTcc###cccTTccccHHHHHHHHHHHHHHTTcccccccccTTcccHHHHHHHHTTHHHHHHHHHc####################cTTccccc############ccHHHHccccccccTTTccHHHHHHHHHHHTccccccHHHHHHHHHHHHH## DISOP:02AL 647-648| PSIPRED ccccccccccccccccccccccccccccEEEEEEEEccHHHcccccccccccccccccHHHHHHHHHHHHHHHHccccccEEEEEEEcccccccccccccccccccccEEEEEcccccccHHHHHHHHHHHcccccccccccccccHHHHHHHHHHHHHHHHHHHHHccccEEEEEcccccccccccHHHHHHHHHHHHHHHHcEEEEEEEcccccccccccHHHHHHcccccccccHHHHccccccccccccHHHHHHHHHHHHHHccccccEEEcccEEEEcccEEEEEEEEEEEEEccccccEEEEcccccEEEEEEEEEEEcccccccccHHHEEEEEEEccEEEEccHHHHHHccccccccEEEEEEEEHHHccHHHcccccEEEEEccccccHHHHHHHHHHHHHHHcccEEEEEEEEccccccEEEEEEEEcccccccccccccccEEEEEcccHHHcccccccccccccHHHHHHHHHHHHHHHcccccccHHHcccHHHHHHHHHHHHHHccccccccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccccccccccccccccccccccccHHHHHHHHHcccEEEEEHHHHHHHHHHcccccccccHHHHHHHHHHHccc //