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Clostridium perfringens str. 13 (cper0)
Gene : CPE0539
DDBJ      :CPE0539      NAD-dependent 4-hydroxybutyrate dehydrogenase
Swiss-Prot:             

Homologs  Archaea  30/68 : Bacteria  585/915 : Eukaryota  139/199 : Viruses  0/175   --->[See Alignment]
e.22.1
:371 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   82->284 1j5rA PDBj 3e-23 37.9 %
:RPS:PDB   81->371 2bi4A PDBj 2e-39 22.2 %
:RPS:SCOP  82->371 1rrmA  e.22.1.2 * 6e-55 23.6 %
:HMM:SCOP  3->352 1o2dA_ e.22.1.2 * 5.7e-69 28.9 %
:RPS:PFM   82->281 PF00465 * Fe-ADH 2e-39 45.8 %
:HMM:PFM   28->363 PF00465 * Fe-ADH 1.3e-72 30.6 330/365  
:BLT:SWISS 1->371 4HDB_CLOK5 e-102 50.4 %
:PROS 250->270|PS00060|ADH_IRON_2
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAB80245.1 GT:GENE CPE0539 GT:PRODUCT NAD-dependent 4-hydroxybutyrate dehydrogenase GT:DATABASE GIB00075CH01 GT:ORG cper0 GB:ACCESSION GIB00075CH01 GB:LOCATION 668530..669645 GB:FROM 668530 GB:TO 669645 GB:DIRECTION + GB:GENE CPE0539 GB:PRODUCT NAD-dependent 4-hydroxybutyrate dehydrogenase GB:NOTE 371 aa, similar to sp:4HDB_CLOKL NAD-DEPENDENT 4-HYDROXYBUTYRATE DEHYDROGENASE (EC 1.1.1.61) (4HBD from Clostridium kluyveri (371 aa); 47.2% identity in 371 aa overlap. 1 putative transmembrane region was found by PSORT GB:PROTEIN_ID BAB80245.1 LENGTH 371 SQ:AASEQ MKLLSLNTEILGFDTSSEFAKELNLNEKDLVFTNRRIYEGSFKSLDLKCNYVLKDKYNFNEPNDEIIDEIFKDIKNIDFNRVIAIGGGSILDVGKLLALKDVDSTKKLFKRELPIIRDKELIIVPTTCGTGSEVTNISIVEIKSENTKLGLAVDELYADKGVLIPELCKTMPYKAFVYSSIDALIHSIEGFLSPNSTPYTDLFAFKAIEMILSGYKEIIEKGEEYRNTIMDKFLIASNYAGIAFGNAGVGAVHALSYPLGGKYHVPHGEANYQFLMAVLNFYKKNNGDGKISELTKLISSIINAKEEDCYLELENLLNNLIRRKNLKEYGMTIDEIEKFSQSVMKNQQRLLKNNYVSMEIKDMEEIYKSLY GT:EXON 1|1-371:0| BL:SWS:NREP 1 BL:SWS:REP 1->371|4HDB_CLOK5|e-102|50.4|371/371| PROS 250->270|PS00060|ADH_IRON_2|PDOC00059| SEG 63->79|ndeiideifkdiknidf| SEG 311->328|lelenllnnlirrknlke| BL:PDB:NREP 1 BL:PDB:REP 82->284|1j5rA|3e-23|37.9|190/359| RP:PDB:NREP 1 RP:PDB:REP 81->371|2bi4A|2e-39|22.2|284/382| RP:PFM:NREP 1 RP:PFM:REP 82->281|PF00465|2e-39|45.8|192/364|Fe-ADH| HM:PFM:NREP 1 HM:PFM:REP 28->363|PF00465|1.3e-72|30.6|330/365|Fe-ADH| GO:PFM:NREP 3 GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF00465|IPR001670| GO:PFM GO:0046872|"GO:metal ion binding"|PF00465|IPR001670| GO:PFM GO:0055114|"GO:oxidation reduction"|PF00465|IPR001670| RP:SCP:NREP 1 RP:SCP:REP 82->371|1rrmA|6e-55|23.6|280/385|e.22.1.2| HM:SCP:REP 3->352|1o2dA_|5.7e-69|28.9|343/359|e.22.1.2|1/1|Dehydroquinate synthase-like| OP:NHOMO 1714 OP:NHOMOORG 754 OP:PATTERN 11111-----1--1--1----1-3------1---1---1---111-11--111-1211221--2---1 -1------222----------1--12-----131111234-1------1---121-------1--11----21112222-11-11-112112-111--------11---1---------------223321122-222222---112-11--111-----11---1------------------1---43343322222222222222252545322216351113334441-111111111111111-11--213-11-21-1223311311112111111111111122222222222-111111111111211---111124359444444484837FF3897453112542244469-12325314113-111--------1-2-----1522211111111112--15--4-2321-3442223624332-112-1221222111-1111113------2-----------------------------1-1111-22123234433111122221222325123342-1121121112133221111--12--------1--11--743A455457556-42322-683----221-11-1----1------------1-----43522-123-12333323743343432443-----1-------63542314446466654-4444465444465444445798342336645565555555555323233341-222221222222---------1111-2226333415--------233333332222-11221522423112222---------222243333344434-----------------2--1111----------1-------------------------2212342334--1 --2211--21-1--1121122221312111111111111111111111122121111111111---1-1------11111------21-111211111112-1111-1311111122--1111-11-1-241--3-11-11-1-1111--1--1-1111111-31--1127112--321811-1-----1--1-1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 354 STR:RPRED 95.4 SQ:SECSTR #################HHHHHHccccEEEEEEEHHHHHHHHHHHHHHHHHHTTTcccccEEEEEEEcccGGGccHHHHHEEEEEccHHHHHHHHHTTcGGGccccTTcEEcccccccccEEEEcccccccTTTccEEEEEccTTccEEEEEcTTccccEEEEcHHHHTTccHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHTTHHHHHTTcHHHHHHHHHHHHHHHHHHHHHHTTTcccHHHHTTHHHHHHHcccHHHHHHHHHHHHHHHHGGGcTTHHHHHHHHTTTccHHHHHHHHHHHHHHHHHHHTccccTTTTTccGGGHHHHHHHHHHHHcGGGGGccccccHHHHHHHHHHHc DISOP:02AL 3-4| PSIPRED ccccccccEEEcHHHHHHHHHHccccccEEEEEcHHHHHHHHHHHHHcccEEEEEccccccccHHHHHHHHHHHHHccccEEEEEcccHHHHHHHHHHHHHccHHHHHHcccccccccccEEEEcccccccccccccEEEEEccccEEEEEEcHHHccEEEEEcHHHHHHccHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHccccccHHHccccHHHHHHHHHHHHHHHHHHcccccccccHHHHHHHHHHHc //