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Clostridium perfringens str. 13 (cper0)
Gene : CPE0866
DDBJ      :CPE0866      probable alpha-N-acetylglucosaminidase
Swiss-Prot:             

Homologs  Archaea  0/68 : Bacteria  31/915 : Eukaryota  90/199 : Viruses  0/175   --->[See Alignment]
b.1.2b.18.1c.1.8
:2104 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   46->920 2vcaA PDBj 0.0 97.5 %
:BLT:PDB   926->1012 2berA PDBj 2e-05 25.8 %
:BLT:PDB   1365->1501 2v72A PDBj 5e-28 45.5 %
:BLT:PDB   1515->1699 2vcaA PDBj 1e-09 24.4 %
:BLT:PDB   1685->1925 3g6bB PDBj 2e-04 23.0 %
:BLT:PDB   2012->2102 2w1nA PDBj 4e-33 70.3 %
:RPS:PDB   46->163 3bn6A PDBj 3e-08 12.0 %
:RPS:PDB   312->641 3ecqA PDBj 1e-07 8.4 %
:RPS:PDB   942->1015 3bn6A PDBj 4e-06 18.4 %
:RPS:PDB   1074->1317 3cqoA PDBj 1e-07 10.7 %
:RPS:PDB   1370->1628 3cqoA PDBj 6e-21 14.4 %
:RPS:PDB   2019->2102 2ed8A PDBj 3e-10 28.6 %
:RPS:SCOP  51->163 1jhjA  b.18.1.9 * 3e-12 15.4 %
:RPS:SCOP  304->740 1gowA  c.1.8.4 * 2e-10 12.0 %
:RPS:SCOP  926->1067 1k12A  b.18.1.15 * 1e-10 12.3 %
:RPS:SCOP  1070->1207 1jhjA  b.18.1.9 * 4e-11 11.3 %
:RPS:SCOP  1212->1349 1jhjA  b.18.1.9 * 9e-10 14.8 %
:RPS:SCOP  1368->1502 1eutA2  b.18.1.1 * 1e-18 28.9 %
:RPS:SCOP  1519->1628 1tvgA  b.18.1.9 * 2e-12 13.3 %
:RPS:SCOP  2018->2102 1x5lA1  b.1.2.1 * 4e-11 24.7 %
:HMM:SCOP  32->165 1tvgA_ b.18.1.9 * 7e-24 28.4 %
:HMM:SCOP  928->1046 1w8oA2 b.18.1.1 * 5.7e-16 26.5 %
:HMM:SCOP  1072->1212 1tvgA_ b.18.1.9 * 1e-16 23.0 %
:HMM:SCOP  1214->1354 1tvgA_ b.18.1.9 * 4.3e-17 24.4 %
:HMM:SCOP  1364->1505 1k3iA2 b.18.1.1 * 4.1e-31 33.8 %
:HMM:SCOP  1506->1631 1k3iA2 b.18.1.1 * 3e-20 27.2 %
:HMM:SCOP  2018->2102 1fnhA1 b.1.2.1 * 1.8e-11 26.5 %
:RPS:PFM   55->115 PF00754 * F5_F8_type_C 3e-06 34.3 %
:RPS:PFM   243->900 PF05089 * NAGLU e-174 49.8 %
:RPS:PFM   949->1028 PF00754 * F5_F8_type_C 2e-07 29.6 %
:RPS:PFM   1033->1097 PF05568 * ASFV_J13L 4e-04 29.7 %
:RPS:PFM   1374->1496 PF00754 * F5_F8_type_C 3e-11 31.7 %
:RPS:PFM   1524->1612 PF00754 * F5_F8_type_C 4e-07 30.5 %
:RPS:PFM   1667->2005 PF12128 * DUF3584 6e-06 30.1 %
:RPS:PFM   2019->2091 PF00041 * fn3 5e-05 34.2 %
:HMM:PFM   243->906 PF05089 * NAGLU 7.4e-230 43.1 645/671  
:HMM:PFM   45->159 PF00754 * F5_F8_type_C 8.2e-20 27.8 115/129  
:HMM:PFM   937->1046 PF00754 * F5_F8_type_C 4.5e-19 29.1 110/129  
:HMM:PFM   1090->1205 PF00754 * F5_F8_type_C 5e-08 21.2 113/129  
:HMM:PFM   1227->1327 PF00754 * F5_F8_type_C 2.1e-07 25.3 99/129  
:HMM:PFM   1373->1498 PF00754 * F5_F8_type_C 2.4e-27 32.5 123/129  
:HMM:PFM   1516->1617 PF00754 * F5_F8_type_C 9e-20 29.4 102/129  
:HMM:PFM   1809->1848 PF07554 * FIVAR 0.00013 20.0 40/51  
:HMM:PFM   1888->1922 PF07554 * FIVAR 3.2e-07 28.6 35/51  
:HMM:PFM   2018->2091 PF00041 * fn3 2.6e-11 25.7 74/85  
:BLT:SWISS 15->249 OGA_CLOPE 2e-09 26.2 %
:BLT:SWISS 265->911 ANAG_HUMAN 1e-76 30.2 %
:BLT:SWISS 926->1012 NANH_MICVI 5e-05 25.8 %
:BLT:SWISS 1344->1562 OGA_CLOPE 4e-26 31.8 %
:BLT:SWISS 1634->2104 OGA_CLOPE 7e-34 32.8 %
:PROS 1549->1561|PS00018|EF_HAND_1
:COIL
:REPEAT 4|865->1100|1101->1242|1243->1393|1434->1672
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAB80572.1 GT:GENE CPE0866 GT:PRODUCT probable alpha-N-acetylglucosaminidase GT:DATABASE GIB00075CH01 GT:ORG cper0 GB:ACCESSION GIB00075CH01 GB:LOCATION 1061148..1067462 GB:FROM 1061148 GB:TO 1067462 GB:DIRECTION + GB:GENE CPE0866 GB:PRODUCT probable alpha-N-acetylglucosaminidase GB:NOTE 2104 aa, partially similar to sp:ANAG_HUMAN ALPHA-N-ACETYLGLUCOSAMINIDASE PRECURSOR (EC 3.2.1.50) (N-ACETYL-ALPHA- GLUCOSAMINIDASE) (NAG) from Homo sapiens (743 aa); 29.4% identity in 704 aa overlap GB:PROTEIN_ID BAB80572.1 LENGTH 2104 SQ:AASEQ MFSKKFKKQMAYVLASTFVFGLVNPSAIKVRASTGVEITEGVTVTAKGNTEGNTADLAIDGDLSTYWESSNDYKWIEVDLGGIYELSKIEIFNKDEAVYKYNIYASEDGENFNKIAYKNNDNVSDSNGNVHTIDNVRAGKIRIDVVQNSNSDRVNIAEINVFGKNTGESLPEIKKIATSNFSETPWATEYEKFNSDIAYANEKTLNEIKNLVGRVIGEEFKDKFIFEIRDQLNGNDVFEVSDSRDGKVLIKGNNGVSLASGFNYYLKNYCNVSYNPIMGSNLKMPETMPSVGERVVIDTPYEYRYALNFCTYSYTMSFWDWDQYEEFLDWCAMNGVNLVLDIIGQEEVLRRTLNEFGYSDEEVKEFISGPAYFAWFYMQNMTGFGGPLPNDWFEQRAELGRKMHDRMQSFGINPVLQGYSGMVPRDFKEKNPEAQTISQGGWCGFDRPDMLKTYVNEGEVDYFQNVADVFYEKQKEVFGDVTNFYGVDPFHEGGNTGDLDNGKIYEIIQNKMIEHDNDAVWVIQNWQGNPSNNKLEGLTKKDQAMVLDLFSEVSPDWNRLEERDLPWIWNMLHNFGGRMGMDAAPEKLATEIPKALANSEHMVGIGITPEAINTNPLAHELLFDMAWTRDQINFRTWTEDYIERRYGKTNKEILDAWNIILDTAYKKRNDYYQGAAESIINARPGFGIKSASTWGHSKIVYDKSEFEKAIEIFAKNYDEFKDSDAFLYDFADILKQLLANSAQEYYEVMCNAYNNGNGEKFKFVSGKFLELIKLQERVLSTRPEFLIGNWIEDARTMLKDSDDWTKDLFEFNARALVTTWGSRNNADGGGLKDYSNRQWSGLTEDYYYARWEKWINGLQAELDGGAKAPNIDWFKMEYDWVNKKSDTDKLYPTEASNENLGELAKIAMESYSVTNMDKILGENESVERVNIALGKPVSSETHGETEANPLTNITDGNTGTMWVADKEGYPASVTVDLQGVKSVDGIEFAFRNQAGDRAVAYKVEVMDESGQWKTVSDKSEDYSSKGVIEKVDFTGKAQKVKVSLTNVDLNLSPSYKIPELAEIMVYGGKEKEDEYTNVALGKPVTGAEAENGKPLANITDGDLNSLWVSNNGQTPATTSIDLQETENVEFLELHFEKPGLRFQFKVEVEDANGNKETLLDMTSNKEDNEKSYKIPVGKDINKVHVTMTGKAEGGQHPGAWAAIAEVKAMSKEKPANYVNIAENKNVSGSNSQSGNPLSNITDGDLSSLWISDNGAMPANATIDLEGNSFVDFLELHFEKEGFRFKFKVEVEDESGNRETVLDMTSNTEDNKKSYNIPVKKEISKIHATITGKADGGEYPLAWAAIAEIKAMSKEAINKFEQASIALPQGNMKATATSEHPDVGNEGLAKFAIDGKENTIWHTKYNPVEELPQSITLELGGSYEINKFTYLPRSGAKNGNITKYELHVSEDGNNFRKISEGNWDDSGSLKTLKFNSTKATHVKLVALEGVGGFASAAELNVFAIPENLAMKDETKVEVTSNNSEANNLRDGNENTLWIPEQEEEKSVTFDLSKEKDISAIDIVSKGNSPLKYSIEISNDGTEWTKIVDENNNEENKAVYSNILKSGKIGRFVRFNFNSENVKIGEIKIYKGDSTSSLDSYIRVVEDIYNSAVVGDMAGNYTEEAKESLGNAIDEAKLALGNDINSKEANEVMSTLKSALNEFYKGFVQISRTKLAALISDVDILLNEILPSLMKSMNYNEKAIVNAEIQKLKLENNEAKEVYNKKQVSQSEIDTAYDELKNTLDSYYDAVSAETAYKSMVLLAKEKVENAVVGNGNGQYPKEAVDALNEAIRIAEEGFESSTSLEDIRNITRTLKEAIDTFVESVNVIDKAQLEEIISSIESKLENAEGVYIPNAIEELRKALDKAKEVLNNEGANEENINKAISDLTEAEAKFELSKVPNKDELNSEIERAYDVLEKLKGFDHLEGIKIKLEDAILEAERVKNDENSLKVDVDKVLGELKIVIEEALKSIDSSEVIVSPVRDFKATNISKKNVTVQWSAPENSFGLEGYVLYKDGKKVAELGKDETTYKFKGLNRHTIYNFKIAAKYNNGELSSKESITLRTER GT:EXON 1|1-2104:0| BL:SWS:NREP 5 BL:SWS:REP 15->249|OGA_CLOPE|2e-09|26.2|213/1001| BL:SWS:REP 265->911|ANAG_HUMAN|1e-76|30.2|623/743| BL:SWS:REP 926->1012|NANH_MICVI|5e-05|25.8|85/647| BL:SWS:REP 1344->1562|OGA_CLOPE|4e-26|31.8|214/1001| BL:SWS:REP 1634->2104|OGA_CLOPE|7e-34|32.8|445/1001| PROS 1549->1561|PS00018|EF_HAND_1|PDOC00018| COIL:NAA 24 COIL:NSEG 1 COIL:REGION 1900->1923| NREPEAT 1 REPEAT 4|865->1100|1101->1242|1243->1393|1434->1672| SEG 34->45|tgveitegvtvt| SEG 119->130|nndnvsdsngnv| SEG 1873->1881|eeiissies| BL:PDB:NREP 6 BL:PDB:REP 46->920|2vcaA|0.0|97.5|875/886| BL:PDB:REP 926->1012|2berA|2e-05|25.8|85/601| BL:PDB:REP 1365->1501|2v72A|5e-28|45.5|132/137| BL:PDB:REP 1515->1699|2vcaA|1e-09|24.4|184/886| BL:PDB:REP 1685->1925|3g6bB|2e-04|23.0|209/212| BL:PDB:REP 2012->2102|2w1nA|4e-33|70.3|91/228| RP:PDB:NREP 6 RP:PDB:REP 46->163|3bn6A|3e-08|12.0|115/158| RP:PDB:REP 312->641|3ecqA|1e-07|8.4|321/1313| RP:PDB:REP 942->1015|3bn6A|4e-06|18.4|74/158| RP:PDB:REP 1074->1317|3cqoA|1e-07|10.7|242/293| RP:PDB:REP 1370->1628|3cqoA|6e-21|14.4|257/293| RP:PDB:REP 2019->2102|2ed8A|3e-10|28.6|84/106| RP:PFM:NREP 8 RP:PFM:REP 55->115|PF00754|3e-06|34.3|61/126|F5_F8_type_C| RP:PFM:REP 243->900|PF05089|e-174|49.8|636/664|NAGLU| RP:PFM:REP 949->1028|PF00754|2e-07|29.6|80/126|F5_F8_type_C| RP:PFM:REP 1033->1097|PF05568|4e-04|29.7|64/183|ASFV_J13L| RP:PFM:REP 1374->1496|PF00754|3e-11|31.7|120/126|F5_F8_type_C| RP:PFM:REP 1524->1612|PF00754|4e-07|30.5|89/126|F5_F8_type_C| RP:PFM:REP 1667->2005|PF12128|6e-06|30.1|326/1179|DUF3584| RP:PFM:REP 2019->2091|PF00041|5e-05|34.2|73/85|fn3| HM:PFM:NREP 10 HM:PFM:REP 243->906|PF05089|7.4e-230|43.1|645/671|NAGLU| HM:PFM:REP 45->159|PF00754|8.2e-20|27.8|115/129|F5_F8_type_C| HM:PFM:REP 937->1046|PF00754|4.5e-19|29.1|110/129|F5_F8_type_C| HM:PFM:REP 1090->1205|PF00754|5e-08|21.2|113/129|F5_F8_type_C| HM:PFM:REP 1227->1327|PF00754|2.1e-07|25.3|99/129|F5_F8_type_C| HM:PFM:REP 1373->1498|PF00754|2.4e-27|32.5|123/129|F5_F8_type_C| HM:PFM:REP 1516->1617|PF00754|9e-20|29.4|102/129|F5_F8_type_C| HM:PFM:REP 1809->1848|PF07554|0.00013|20.0|40/51|FIVAR| HM:PFM:REP 1888->1922|PF07554|3.2e-07|28.6|35/51|FIVAR| HM:PFM:REP 2018->2091|PF00041|2.6e-11|25.7|74/85|fn3| GO:PFM:NREP 4 GO:PFM GO:0007155|"GO:cell adhesion"|PF00754|IPR000421| GO:PFM GO:0007155|"GO:cell adhesion"|PF00754|IPR000421| GO:PFM GO:0007155|"GO:cell adhesion"|PF00754|IPR000421| GO:PFM GO:0007155|"GO:cell adhesion"|PF00754|IPR000421| RP:SCP:NREP 8 RP:SCP:REP 51->163|1jhjA|3e-12|15.4|113/161|b.18.1.9| RP:SCP:REP 304->740|1gowA|2e-10|12.0|410/489|c.1.8.4| RP:SCP:REP 926->1067|1k12A|1e-10|12.3|134/158|b.18.1.15| RP:SCP:REP 1070->1207|1jhjA|4e-11|11.3|137/161|b.18.1.9| RP:SCP:REP 1212->1349|1jhjA|9e-10|14.8|137/161|b.18.1.9| RP:SCP:REP 1368->1502|1eutA2|1e-18|28.9|135/142|b.18.1.1| RP:SCP:REP 1519->1628|1tvgA|2e-12|13.3|110/136|b.18.1.9| RP:SCP:REP 2018->2102|1x5lA1|4e-11|24.7|85/98|b.1.2.1| HM:SCP:REP 32->165|1tvgA_|7e-24|28.4|134/0|b.18.1.9|1/6|Galactose-binding domain-like| HM:SCP:REP 928->1046|1w8oA2|5.7e-16|26.5|117/0|b.18.1.1|2/6|Galactose-binding domain-like| HM:SCP:REP 1072->1212|1tvgA_|1e-16|23.0|135/0|b.18.1.9|3/6|Galactose-binding domain-like| HM:SCP:REP 1214->1354|1tvgA_|4.3e-17|24.4|135/0|b.18.1.9|4/6|Galactose-binding domain-like| HM:SCP:REP 1364->1505|1k3iA2|4.1e-31|33.8|142/0|b.18.1.1|5/6|Galactose-binding domain-like| HM:SCP:REP 1506->1631|1k3iA2|3e-20|27.2|125/0|b.18.1.1|6/6|Galactose-binding domain-like| HM:SCP:REP 2018->2102|1fnhA1|1.8e-11|26.5|83/0|b.1.2.1|1/1|Fibronectin type III| OP:NHOMO 211 OP:NHOMOORG 121 OP:PATTERN -------------------------------------------------------------------- 1---2----------------------------------------11--------------------21-------------------5561--------12---2---3-----------------------------------------------------------------------------------------1------1------------------------11--------------------1---1-------------------------------------------------------------------------------------983-------------------------------11------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------1----12---------------------------------------------------------------6 ----11---------1-1--2211-1-11-----------------21222212-----------------------------------22----------------1--2121-1--11111111121281-212-11121121-1-1111-12111113--122111161111----8----11122-11--22221 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 2040 STR:RPRED 97.0 SQ:SECSTR ##############HHHcccccccccEEEEEEccc##########cGGGcTTccGGGGGcccccccGGGcccccEEEEEEEEEEEEEEEEEEcGGGTTEEEEEEcccGGGGTTccccTTccccccEEccccccccEEEEEEEEEEEEEEccccccEEEEEEEEEEcccccccccccccccGGGcHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHTcccGGGccEEEEHHHHHcTTcccccEEETTEEEEEEccHHHHHHHHHHHHHHccTTEEEEEEEEcTTcGGGcccccccEEEEccEcccccEEEEETcccGGGTHHHHHHHHHHHHHTTTEEEEEEEccTTcEccEEcTTcccccTTTccccTTccccEEEEcccEEEEcHHHHHHTTHHHHHHHHHHHHcTTccEEEEEcTTccTTccccHHHHHHHHHHHHTTTcEEEEcccccccHHHHccccccTTccccccHHHHHHHTTTccccccccGGGcGGGcccTTccccEEcccccGGGccccHHHHHHHHHHHHHHHHTTcEEEEEEEcccccEEEETTEEEEEccEEEEEEcTTccEEEEEEccccTTcGGGGcEEEEETTEEEEETTEEEEEEcccTTcccccGGGcEEEEEccccEEEEEcHHHHHHHHHHHHHHHHHHccHHHHHHHHHHcccccccGGGcccccccccccTTccccccccHHHHHHHHHHHHHTHHHHTTcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTcHHHHHHHHHHHHHHHHHHHHHHTTcGGGcHHHHHHHHHHccccccHHHHHHHHHHHHHHTTTcccHHHHTTTccTTTTcccccTHHHHTHHHHHHHHHHHHHHHHTTccccccccHHHHHHHHHTccTTTTcccccccccccHHHHHHHHHHHcccTTHHHHc#####ccGGGcEEEEEcccEEGGGcccGGGccTTcGGGTcccEccccEEccEEEEEEEEEEEEEEEEEEcccccGGTTEEEEEEcccGGGGTTccEEEEEccccTTcEEEEEEEEEEEEEEEEcTTcEEccc#######ccEEEEEE######ccEEGGGGcEEEcccccTTccGGGGGcccccccGGGcccccccEEEEEETTTHHHHHHHHHHHHHHcccccccccccEEEccccccccccccccccccEEcccccccEEEEccccccccEEEEEcccEEEEEccccccccccEEEEEEEEccccTTccccccccEEEEEEccTTcEEcHHHHccTTccccEETTEEEEEEccccccccEEEEEEEEcccccccccEEEETTEEEEEEEEEEcccTcccccccEEEEcTTcccEEEEEEEEHHHccccccTTTHHHHHHHHHcccGGGcEEEEccccccTTccGGGGGGGcccccccGGGccccccccccEEEEEEEEEEEEEEEEEEccccccGGGTEEEEEEcccGGGGcEEEEEccccTTcEEEEEcccccEEEEEEEEcccccccccccEEEEEEEEccccccGGGGcEEEEccccTccccccGGGTcccccccEEccEEEEEEEEEEEEEEEEEEGGGGTTEEEEEEcccGGGGTTccEEEEEccccTTcEEEEEEEEEEEEEEEEETcEEcccccEEEEEEEEcccccccccccccccGGGcHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHTcGHHHHHHHHHHHHHHHHHHHHH#HHHHHHHHHHHHTTTTHHHHHHHHHHHH#HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHH#HHH##HHHHHHHHHHHHHHHHHHHHHHHHHHHHH###HHHHHHHHHHHHHHHHHHHHHHHHHHHH#############ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTcTTccH#HHHHHHHHHHHHHHHHHHHHHHHcccTTccTTTccEEEEEEccccTTcEEEEEEcccTEEEEEEEEGGGGEEccccccccccEEEEEEcccTTEEEEEEEcccccccccEEEEETTTccEEEEEEccccEEEEcccTTcEEEEEEEEEccccEEEEcccEEEEccc DISOP:02AL 1-4, 43-52, 890-893, 895-896, 938-947, 2013-2014, 2088-2104| PSIPRED ccccccccEEEEEEEEEccEEcccccEEEEEcccccHHHcccEEEEccccccccccEEEccccccccccccccEEEEEEcccEEEEEEEEEEcccccEEEEEEEEEcccccEEEEEEccccccccccEEEEEEccccEEEEEEEEEccccccEEEEEEEEEEccccccccccccccccccccccccccccHHHccHHHcccccccHHHHHHHHHHcccccccEEEEEEEcccccccEEEEEEccccEEEEEcccHHHHHHHHHHHHHHHHccEEccccccccccccccccccccEEEEcccccEEEEEEEcccEEEccccHHHHHHHHHHHHHccccHHHHHccHHHHHHHHHHHccccHHHHHHHcccccHHHHHHHcccccccccccHHHHHHHHHHHHHHHHHHHHccccEEccHHcccccHHHHHHccccEEEEccccccccccccccccccccccHHHHHHHHHHHHHHHHHHccccccccccccccccccccccHHHHHHHHHHHHHHHcccEEEEEEcccccHHHHHHHHcccccEEEEEEEccccccccccHHHccccEEEEEEEccccccccEEcHHHHHccHHHHccccccEEEEEcccccccccHHHHHHHHHHccccccccHHHHHHHHHHHccccccHHHHHHHHHHHHHHccccHHHccccccEEEEEcccccccEEEccccccccccHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHHcccHHHHHHHHcccccEEEEEEEccccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHcccccccccccccccccHHHHHHHHHHHccccEEEEEEEEccccccccccccccEEEEEEcccccccccEEEEEcccccEEEccccccccEEEEEcccEEEEEEEEEEEcccccccEEEEEEEEEccccEEEEEEEEEEEccccccEEEEccccEEEEEEEEEEEccccccccccEEEEEEEEEcccccccccccccccccEEEEEcccccccHHHHccccccccEEccccccccEEEEEcccEEEEEEEEEEEEccccEEEEEEEEEEcccccEEEEEccccccccEEEEEEEcccEEEEEEEEEEcccccccccccEEEEccEEEcccccccccHHHccccEEEccccccccccccccccccccEEEccccccccEEEEEcccEEEEEEEEEEEEccccEEEEEEEEEcccccccccccccccccccEEEEEEEccccccEEEEEEEEEccccccccEEEEEEEEEEccccccccccccccEEccccEEEEEEEccccccccccHHHEEccccccEEEEcccccccccEEEEEEcccEEEEEEEEEEEccccccccEEEEEEEEEccccEEEEEEEEEcccccEEEEEEEcccEEEEEEEEEEccccccEEEEEEEEEEcccccccccccccccccccccHHHHHHcccccccccccccccEEEEEccccEEEEEEEEEEcccccEEEEEEEEcccccEEEEEEcccccccccEEEEEEccccEEEEEEEEccccccEEEEEEEEcccccccccccccEEEEccccEEEEEcccccccHHHHHHHcccccEEEEcccccccccccHHHHHHHcccHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHccccccccHHHHHHccccHHHHHHccccccccccccccccccccccccccccccccHHHccccEEccccccccEEcccccccccHHHHHcccEEEEEcccHHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHccccccccccccccHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHccccccccccccEEEEHHHHHHHHHHccccEEEEEEEccccccccccccEEEccccccccccccccccEEEEcccEEEEEEEEcccccccEEEEEEEccccEEEEEcccEEEEEEcccccccEEEEEEEEEEccccccccccEEEEEcc //