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Clostridium perfringens str. 13 (cper0)
Gene : cpdA
DDBJ      :cpdA         2', 3'-cyclic nucleotide 2'-phosphodiesterase
Swiss-Prot:             

Homologs  Archaea  12/68 : Bacteria  526/915 : Eukaryota  130/199 : Viruses  0/175   --->[See Alignment]
d.114.1d.159.1
:1215 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   51->320 3gveA PDBj 1e-30 36.0 %
:BLT:PDB   629->1069 1ushA PDBj 5e-46 32.0 %
:RPS:PDB   48->582 3c9fB PDBj 4e-43 11.7 %
:RPS:PDB   628->1104 3c9fB PDBj 1e-55 14.3 %
:RPS:SCOP  52->336 2z1aA2  d.159.1.2 * 3e-31 19.0 %
:RPS:SCOP  375->579 2z1aA1  d.114.1.1 * 2e-21 15.5 %
:RPS:SCOP  635->921 2z1aA2  d.159.1.2 * 4e-37 25.9 %
:RPS:SCOP  922->1102 2z1aA1  d.114.1.1 * 8e-39 33.7 %
:HMM:SCOP  45->344 1hp1A2 d.159.1.2 * 6e-75 39.7 %
:HMM:SCOP  353->581 1hp1A1 d.114.1.1 * 7.8e-26 25.8 %
:HMM:SCOP  628->924 1hp1A2 d.159.1.2 * 1.2e-81 37.6 %
:HMM:SCOP  925->1112 1hp1A1 d.114.1.1 * 5e-47 36.3 %
:RPS:PFM   411->526 PF02872 * 5_nucleotid_C 1e-07 25.0 %
:RPS:PFM   942->1069 PF02872 * 5_nucleotid_C 8e-30 45.3 %
:HMM:PFM   355->528 PF02872 * 5_nucleotid_C 2.7e-32 27.3 132/151  
:HMM:PFM   928->1070 PF02872 * 5_nucleotid_C 8e-40 35.5 141/151  
:HMM:PFM   54->269 PF00149 * Metallophos 9.6e-18 22.1 181/200  
:HMM:PFM   636->851 PF00149 * Metallophos 4.6e-16 16.9 189/200  
:BLT:SWISS 27->581 CN16_HAEIN 1e-51 32.3 %
:BLT:SWISS 622->1139 YHCR_BACSU 4e-56 33.5 %
:PROS 53->65|PS00785|5_NUCLEOTIDASE_1
:PROS 130->141|PS00786|5_NUCLEOTIDASE_2
:TM
:REPEAT 2|29->566|612->1097
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAB81657.1 GT:GENE cpdA GT:PRODUCT 2', 3'-cyclic nucleotide 2'-phosphodiesterase GT:DATABASE GIB00075CH01 GT:ORG cper0 GB:ACCESSION GIB00075CH01 GB:LOCATION complement(2236515..2240162) GB:FROM 2236515 GB:TO 2240162 GB:DIRECTION - GB:GENE cpdA GB:PRODUCT 2', 3'-cyclic nucleotide 2'-phosphodiesterase GB:NOTE 1215 aa, similar to gp:AB028630_4 2', 3'-cyclic nucleotide 2'-phosphodiesterase from Clostridium perfringens (865 aa); 99.9% identity in 865 aa overlap. Putative N-terminal signal sequence and 1 putative transmembrane region were found by PSORT CPE1951 GB:PROTEIN_ID BAB81657.1 LENGTH 1215 SQ:AASEQ MLKKFSNKKITALMVVLAMVFSFILPIPVKAAEISETKNSNVTEKTDKKTVNIQILATSDLHGKFMDYDYAQGEESVGGLNQIATVVKEAKKENPNTLVLDNGDTIQGNYNHLFMNKENPMILAMNTIGYDVFSLGNHEFNFGMDKLHNIIGQANPNLHVLCGNLYRNGERVFNPYTIKDVDGIKVAIIGVVTPHIMQWDSQNLKGYEAKNPTEEVKKIIGEIKANGGADVYVVTSHASLNGEYGDGDSAAGIAEANPEVSVVVAGHSHDTVKSELRGNAIISEPASRAKYVSKFNLTVEKDESGTKVLDKNADLISLKGVQGDPELTEKLKPFHEAAINDATAKIGELKGGDLAKPDEVKGIPQSIVEDQGVTDFINEVQLYNSKKFLQTKGIDPNNVYMVSSAALFSPKANLKEGPISKADVSNIYKFDNKLYVIKTNGKQLKKYMEENSKFFNKYKDGDLTISFDENVRMYKYDMFEGVNYEINIAKDPGERIENLKFSKDGKPVEDSDVVYLSVNDYRYNSGLAAGIMDSGEHEKIYDTVNDDISAIRDLISDYIINVKHGVINRNVDGNWKITGNNWNPEQRALAVKLINEGKIKLPTSSNGRTPNVKSVTWGEVSKFAEALPEEKKEVEIPILTFNDFHGSLKESGGNPGAAKFVGELKKVKEKNPNTIVVSGGDMYQGSALSNLLKGKPVSDMNKALGVQFSSVGNHEFDWGYDLIPGWAKDGGFEFLASNIYEKATGEPVKWAKPYGVVEKGGKKIGFIGLATPETAYKTNPDNVKDLEFRDPNTEAEKWVKHLREVEKVDAVIALTHIGSQQDRKTGEITGEVVNLTKVPGLDAIVSAHSHMPVKGIVNGVPIVQAYKNGRAIGLIDLKFDKDGKLSVEAQRMDISKNIKDLPVDKEMEETLGKYEKELSPILDVKVADLSEDLPHNRDAGVSPMGATVTETMRKIVDADIAINNGGGVRAPLKKGVITVGDMYTILPFDNTIVTMDMKGSDIIKVLEHGIAPKDFGWGQHAGLKFWYNPDAEPGNRITSVRLLDGSKLDPNKYYKLATNDFMAAGGDGYDFSAARNIKDTNKVLREGISDYWKNHGINPITNLATLIEPGEDKGEAVKPVEPENPSVDSNKPVEQEKPSIDTNKPMDPTIDDINTDKPEISNPDNNSNNEENKKDDLIKLPNTGNPFGAEVFAAMGVLATIGGSIILKKKHNDAA GT:EXON 1|1-1215:0| BL:SWS:NREP 2 BL:SWS:REP 27->581|CN16_HAEIN|1e-51|32.3|533/657| BL:SWS:REP 622->1139|YHCR_BACSU|4e-56|33.5|507/1217| PROS 53->65|PS00785|5_NUCLEOTIDASE_1|PDOC00627| PROS 130->141|PS00786|5_NUCLEOTIDASE_2|PDOC00627| TM:NTM 1 TM:REGION 10->32| NREPEAT 1 REPEAT 2|29->566|612->1097| SEG 1158->1176|peisnpdnnsnneenkkdd| BL:PDB:NREP 2 BL:PDB:REP 51->320|3gveA|1e-30|36.0|264/328| BL:PDB:REP 629->1069|1ushA|5e-46|32.0|431/515| RP:PDB:NREP 2 RP:PDB:REP 48->582|3c9fB|4e-43|11.7|501/540| RP:PDB:REP 628->1104|3c9fB|1e-55|14.3|462/540| RP:PFM:NREP 2 RP:PFM:REP 411->526|PF02872|1e-07|25.0|104/158|5_nucleotid_C| RP:PFM:REP 942->1069|PF02872|8e-30|45.3|128/158|5_nucleotid_C| HM:PFM:NREP 4 HM:PFM:REP 355->528|PF02872|2.7e-32|27.3|132/151|5_nucleotid_C| HM:PFM:REP 928->1070|PF02872|8e-40|35.5|141/151|5_nucleotid_C| HM:PFM:REP 54->269|PF00149|9.6e-18|22.1|181/200|Metallophos| HM:PFM:REP 636->851|PF00149|4.6e-16|16.9|189/200|Metallophos| GO:PFM:NREP 4 GO:PFM GO:0009166|"GO:nucleotide catabolic process"|PF02872|IPR008334| GO:PFM GO:0016787|"GO:hydrolase activity"|PF02872|IPR008334| GO:PFM GO:0009166|"GO:nucleotide catabolic process"|PF02872|IPR008334| GO:PFM GO:0016787|"GO:hydrolase activity"|PF02872|IPR008334| RP:SCP:NREP 4 RP:SCP:REP 52->336|2z1aA2|3e-31|19.0|276/302|d.159.1.2| RP:SCP:REP 375->579|2z1aA1|2e-21|15.5|174/205|d.114.1.1| RP:SCP:REP 635->921|2z1aA2|4e-37|25.9|282/302|d.159.1.2| RP:SCP:REP 922->1102|2z1aA1|8e-39|33.7|181/205|d.114.1.1| HM:SCP:REP 45->344|1hp1A2|6e-75|39.7|290/0|d.159.1.2|1/2|Metallo-dependent phosphatases| HM:SCP:REP 353->581|1hp1A1|7.8e-26|25.8|186/0|d.114.1.1|1/2|5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain| HM:SCP:REP 628->924|1hp1A2|1.2e-81|37.6|295/0|d.159.1.2|2/2|Metallo-dependent phosphatases| HM:SCP:REP 925->1112|1hp1A1|5e-47|36.3|182/0|d.114.1.1|2/2|5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain| OP:NHOMO 1415 OP:NHOMOORG 668 OP:PATTERN -----------------------1322-1-11--1--------13-21-------------------- --2--1-13321-------------------------11-----2211111-112-1---11221-1222-----321--1-1111114423-211---222242--2-2---------------111---1-11-11111---3----1---1111------31--1---------------43211113123339484564655665333333566131332322222244133434333333333222323223223-3321-11221--2--1112331111122-----------11111111111112443314442-4121-------3-424--133232---1--------21--1-111-2-22-----------1-3331-121222------------1221212-12--222222222212-1---3232122333--------1----111-------------------------------1--------111111-111111--11111111-211211222212222-1---2114---3------------11-11---2-111---1---1----111-163111--1-------1-11111111--13--441-11-11213333333533333334344-----11------22221222224255522-222255424225322222332333323344444443433434242333213--311113313211---------1111112-3333232-22211--2111-111---1------1--11-1-1---1--------134454344365343--------------1114--------------211------11-1---1111---1----2222212111-11 --11--1-----4632222222211111111113231111111111--22222232222222---------------------------1--242111-1---111-223D3121121-1111-211113B1-111-1-111-121111-1--211111123533359AAB--13-32----12-----2--1-33351 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 1012 STR:RPRED 83.3 SQ:SECSTR ###############################################cccccEEEEEEccccccccTTcccHHccHHHHHHHHHHHHHHHHHHccccEEEEcccccTTTcccHHHHTTTTcccHHHHcccEEEcccHHHHTccHHHHHHGGGTcccEEcccccEEEEEEcTTcccEEEEEEcccEEEEHHHHHccccTTccccccccccHHHHHHHHHHHHHHHHHccccEEEEEccccccccccccccHHHHHHHHTTccEEEEcccccEEEEEcTTccEEEEEccccccccccTTGGGccTTcEEEEccTTcccEEEEEEEccEEEEEEEETTccEEEEEEHHHHHHHHHTTTTcEEEEEEccccccccccTTcTTcHHHHHHHTTGGGccccTTccEEEEEEGGGGcccccccEEEEHHHHHHHccccccEEEEEEEHHHHTTHHHHHHcccccccGGGGccccccTTcccccTTTTccccccccccTTccccccTTccEEEEEccccccEcccccTTcccccHHccccEEccccccccEEEEEcccccccEEEEEEEGGGHHHHHHHHHHTTcccccc#############################################ccccccccEEEEEEcccTTcTGcccHHHHHHHHHHHHHHHHHTTcEEEEEEccccccccHHHHccTTTTTHHHHTTccccEEcccGGGTccHHHHHHHHHHHTTTTcccccEEEEcTTccEEEccEEEEcTTTccEEEEEEcccccccccTTEEEccHHHHTccccHTTcHHHHHHTTccccEEEEEccccccTTTcHHHHHHHHHHHHcTTcEEEEEEcccccEEEEEEETTEEEEEccTTcEEEEEEEccccGGGcccHHHHEEEEEEEccHHHHHHHHTccTTcccHHHHHHHHHHHHHHHHTTTTcEEEEEcHHTTGGGccccTTccEEEEEEGGGcccccccEEEEHHHHHHHccccccEEEEEEEHHHHTTHHHHcccccccccTTTTccccccccccTTccccccTTcccccccccEcEEcccccTTcccccccccccccccEEEEEEcccccEEEEEEEGGGHHHHHHH############################################################################################################### DISOP:02AL 1-5, 36-46, 1115-1178, 1212-1215| PSIPRED ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccccEEEEEEEEccEEEEEccccccccccccccHHHHHHHHHHHHHccccEEEEEccccccccccccccccccHHHHHHHHcccEEEEEccHHHHccHHHHHHHHHHHcccccEEEEEEEcccccccccEEEEEEccEEEEEEEEEccHHHHHccccccccEEEcHHHHHHHHHHHHHHHccccEEEEEEccccccccccHHHHHHHHHHccccEEEEccccccEEEccccccEEEEEccccccEEEEEEEEEEEccccEEEEEEccEEEEEccccccHHHHHHHHHHHHHHHHHHccccEEEEccccccccEEccccHHccccccHHHHHHHHHHHHHHHHHHHcccccccEEEEEcccccccccccccccccHHHHHHHHccccEEEEEEEcHHHHHHHHHHHHHHHccccccccEEEcccccccccccEEEEEEEEEEccccccccEEEEEEEEccEEEccccEEEEEEEEEEEcccccccccccccccEEEEcccccHHHHHHHHHHHHHHHcccEEEEEEcccEEEEEcccccccHHHHHHHHcccccEEEEccccccccccccccccccccccccccccccEEEEEEEEccEEEEEEcccccccHHHHHHHHHHHHHccccEEEEEccccccccEEEEEcccHHHHHHHHHccccEEEcccccccccHHHHHHHHHHccccEEEEEEEEccccccccccccEEEEEEccEEEEEEEcccHHHHHccccccccccEEEcHHHHHHHHHHHHHHHccccEEEEEEcccccccHHHHHHHHHHHHHHcccccEEEEcccccEEEEEEcccEEEEEccccccEEEEEEEEEEcccEEEEEEEEEEEccccccccccHHHHHHHHHHHHHHHHHHccccEEEccccccccccccccHHHHHHHHHHHHHcccEEEEEccccccccccccccHHHHHHHHccccEEEEEEEcHHHHHHHHHHHHccccccccEEccEEEEEEcccccccEEEEEEEEccEEcccccEEEEEEEEEEcccccccccccccccccccccHHHHHHHHHHHccccccccccEEEccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccHHHHHHHHHHHHHHHHHHHHHHHccccc //