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Clostridium perfringens str. 13 (cper0)
Gene : ddlA
DDBJ      :ddlA         D-alanine-D-alanine ligase
Swiss-Prot:DDLA_CLOPE   RecName: Full=D-alanine--D-alanine ligase A;         EC=6.3.2.4;AltName: Full=D-alanylalanine synthetase A;AltName: Full=D-Ala-D-Ala ligase A;

Homologs  Archaea  3/68 : Bacteria  868/915 : Eukaryota  13/199 : Viruses  0/175   --->[See Alignment]
c.30.1d.142.1
:301 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->293 1iovA PDBj 5e-49 36.3 %
:RPS:PDB   1->296 3e5nA PDBj 1e-39 35.5 %
:RPS:SCOP  2->92 1ehiA1  c.30.1.2 * 3e-24 31.9 %
:RPS:SCOP  94->297 1e4eA2  d.142.1.1 * 1e-44 29.9 %
:HMM:SCOP  1->93 1e4eA1 c.30.1.2 * 1.9e-29 45.2 %
:HMM:SCOP  94->293 1e4eA2 d.142.1.1 * 1.8e-44 37.6 %
:RPS:PFM   1->83 PF01820 * Dala_Dala_lig_N 6e-16 50.6 %
:RPS:PFM   101->293 PF07478 * Dala_Dala_lig_C 6e-40 43.0 %
:HMM:PFM   109->293 PF07478 * Dala_Dala_lig_C 1.8e-52 39.1 184/203  
:HMM:PFM   1->45 PF01820 * Dala_Dala_lig_N 2e-15 46.7 45/117  
:HMM:PFM   50->84 PF01820 * Dala_Dala_lig_N 6.7e-13 48.6 35/117  
:BLT:SWISS 1->301 DDLA_CLOPE e-171 100.0 %
:PROS 61->72|PS00843|DALA_DALA_LIGASE_1
:PROS 239->266|PS00844|DALA_DALA_LIGASE_2

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAB81021.1 GT:GENE ddlA GT:PRODUCT D-alanine-D-alanine ligase GT:DATABASE GIB00075CH01 GT:ORG cper0 GB:ACCESSION GIB00075CH01 GB:LOCATION complement(1555884..1556789) GB:FROM 1555884 GB:TO 1556789 GB:DIRECTION - GB:GENE ddlA GB:PRODUCT D-alanine-D-alanine ligase GB:NOTE 301 aa, similar to sp:DDL_HAEIN D-ALANINE-D-ALANINE LIGASE (EC 6.3.2.4) (D-ALANYLALANINE SYNTHETASE) (D-ALA-D-ALA LIGASE) from Haemophilus influenzae Rd (306 aa); 40.7% identity in 295 aa overlap CPE1315 GB:PROTEIN_ID BAB81021.1 LENGTH 301 SQ:AASEQ MKVGVIMGGISSEREISIQSGNSVVHALDKDKYEAIPIVLNEKEDLIEKVKGIDFALLALHGKFGEDGTVQSVLKTLGIPFSGCGPLSSAICMDKDMTKRILAFGNVRTARWEMVSSVDEIDYEKIENLGYPVFVKPNNGGSSVATTLVESKEAVKDAVLEALKYDTEVMIEEYIKGDEITCPIIDGKMLPVLAIKPKGKFFDIASKYGDGGADEFIVELNEDLHKEVEKMALETYKLLKCDVYARVDMLVKDNIPYVLEVNTLPGMTKNSLFPKSAAGINMSFEELLDTIIEKSLKVNRE GT:EXON 1|1-301:0| SW:ID DDLA_CLOPE SW:DE RecName: Full=D-alanine--D-alanine ligase A; EC=6.3.2.4;AltName: Full=D-alanylalanine synthetase A;AltName: Full=D-Ala-D-Ala ligase A; SW:GN Name=ddlA; OrderedLocusNames=CPE1315; SW:KW ATP-binding; Cell shape; Cell wall biogenesis/degradation;Complete proteome; Cytoplasm; Ligase; Magnesium; Manganese;Metal-binding; Nucleotide-binding; Peptidoglycan synthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->301|DDLA_CLOPE|e-171|100.0|301/301| GO:SWS:NREP 8 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0008360|"GO:regulation of cell shape"|Cell shape| GO:SWS GO:0007047|"GO:cellular cell wall organization"|Cell wall biogenesis/degradation| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0009252|"GO:peptidoglycan biosynthetic process"|Peptidoglycan synthesis| PROS 61->72|PS00843|DALA_DALA_LIGASE_1|PDOC00659| PROS 239->266|PS00844|DALA_DALA_LIGASE_2|PDOC00659| BL:PDB:NREP 1 BL:PDB:REP 2->293|1iovA|5e-49|36.3|292/306| RP:PDB:NREP 1 RP:PDB:REP 1->296|3e5nA|1e-39|35.5|282/340| RP:PFM:NREP 2 RP:PFM:REP 1->83|PF01820|6e-16|50.6|83/108|Dala_Dala_lig_N| RP:PFM:REP 101->293|PF07478|6e-40|43.0|193/199|Dala_Dala_lig_C| HM:PFM:NREP 3 HM:PFM:REP 109->293|PF07478|1.8e-52|39.1|184/203|Dala_Dala_lig_C| HM:PFM:REP 1->45|PF01820|2e-15|46.7|45/117|Dala_Dala_lig_N| HM:PFM:REP 50->84|PF01820|6.7e-13|48.6|35/117|Dala_Dala_lig_N| GO:PFM:NREP 5 GO:PFM GO:0005618|"GO:cell wall"|PF01820|IPR011127| GO:PFM GO:0008716|"GO:D-alanine-D-alanine ligase activity"|PF01820|IPR011127| GO:PFM GO:0009252|"GO:peptidoglycan biosynthetic process"|PF01820|IPR011127| GO:PFM GO:0008716|"GO:D-alanine-D-alanine ligase activity"|PF07478|IPR011095| GO:PFM GO:0009252|"GO:peptidoglycan biosynthetic process"|PF07478|IPR011095| RP:SCP:NREP 2 RP:SCP:REP 2->92|1ehiA1|3e-24|31.9|91/132|c.30.1.2| RP:SCP:REP 94->297|1e4eA2|1e-44|29.9|201/211|d.142.1.1| HM:SCP:REP 1->93|1e4eA1|1.9e-29|45.2|93/0|c.30.1.2|1/1|PreATP-grasp domain| HM:SCP:REP 94->293|1e4eA2|1.8e-44|37.6|197/0|d.142.1.1|1/1|Glutathione synthetase ATP-binding domain-like| OP:NHOMO 1101 OP:NHOMOORG 884 OP:PATTERN ----------------------------------------------1-----1--------------1 111-311111121111111-11111111111111111111211312112331111111112232222121211111112221212211111111112--111111111211111111111111111111111112111111111111211112111111111111111111111111111111111111111111111122212222221111112221112111111111331111111111111111111121111111111111111111111111111111111111111121111111111111111111111111111421111111111111211122132111111112211111111222111111-211111111114221111111122222222221-111111111211211123222211111111131111111111111111111111111--------111111111111111111111111111111111111111111112111111211111111111111222111111111111211111111111111112111121111111111111111222233221111111111111111111111111111111111111212111111122111111111-1111111----22112212222222222-2222222222222122222222111112221222222222212222222221121111111111111111111111111122111111111111111111111111111122221212121331222111-111111222211111111112212222222111111112211111111111111--------------------------1212213112121 -----------------------2-21--------------------------------111-----------------------------------------------------------------------------------------------------1---------1----1------2--2--1------1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 297 STR:RPRED 98.7 SQ:SECSTR EEEEEEEEcccTTHHHHHHHHHHHHHHccTTTEEEEEEEEcTccccEEEcTTccEEEEEEccHHHHccHHHHHHHHTTcccccccHHHHHHHHcHHHHHHHHHHTTcccccEEEEETTccHHHHHHHHHcccEEEEEccccccTTcEEEccGGGHHHHHHHHTTTccEEEEEEccccEEEEEEEEEccccEEEEEEEEcccccEEEEEEEEcccEEcccccHHHHHHHHHHHHHHHHHHTcccEEEEEEEcTTccEEEEEEEccccccTTcHHHHHHHTTTccHHHHHHHHHHHHHc#### DISOP:02AL 299-301| PSIPRED cEEEEEEccccccHHHHHHHHHHHHHHHHHccEEEEEEEccccHHHHHHHHcccEEEEcccccccccHHHHHHHHHccccEEcccHHHHHHHHcHHHHHHHHHHccccccccEEEccHHHHHHHHHHHccccEEEEEccccccEEEEEEccHHHHHHHHHHHHHccccEEEEEcccccEEEEEEEcccEEEEEEEEEcccEEccccccccccEEEEcccccHHHHHHHHHHHHHHHHHHccccEEEEEEEEEcccEEEEEEccccccccccHHHHHHHHccccHHHHHHHHHHHHHHcccc //