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Clostridium perfringens str. 13 (cper0)
Gene : folA/folK
DDBJ      :folA/folK    bifunctional folate synthesis protein
Swiss-Prot:             

Homologs  Archaea  1/68 : Bacteria  756/915 : Eukaryota  116/199 : Viruses  0/175   --->[See Alignment]
d.58.30d.96.1
:273 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->267 2cg8C PDBj 2e-47 42.1 %
:RPS:PDB   1->267 2cg8A PDBj 2e-53 41.4 %
:RPS:SCOP  1->118 1dhnA  d.96.1.3 * 6e-28 30.5 %
:RPS:SCOP  120->269 1cbkA  d.58.30.1 * 1e-49 33.6 %
:HMM:SCOP  1->120 1dhnA_ d.96.1.3 * 2.1e-35 41.7 %
:HMM:SCOP  119->273 1cbkA_ d.58.30.1 * 1.7e-52 41.3 %
:RPS:PFM   4->116 PF02152 * FolB 3e-15 37.8 %
:RPS:PFM   123->249 PF01288 * HPPK 6e-28 42.9 %
:HMM:PFM   123->249 PF01288 * HPPK 2.6e-45 44.9 127/127  
:HMM:PFM   4->117 PF02152 * FolB 2.7e-33 39.8 113/113  
:BLT:SWISS 1->271 SULD_STRR6 5e-62 44.1 %
:PROS 206->217|PS00794|HPPK
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAB80728.1 GT:GENE folA/folK GT:PRODUCT bifunctional folate synthesis protein GT:DATABASE GIB00075CH01 GT:ORG cper0 GB:ACCESSION GIB00075CH01 GB:LOCATION 1224445..1225266 GB:FROM 1224445 GB:TO 1225266 GB:DIRECTION + GB:GENE folA/folK GB:PRODUCT bifunctional folate synthesis protein GB:NOTE 273 aa, similar to sp:SULD_STRPN BIFUNCTIONAL FOLATE SYNTHESIS PROTEIN [INCLUDES: DIHYDRONEOPTERIN ALDOLASE (EC 4.1.2.25) (DHNA) from Streptococcus pneumoniae (270 aa); 43.9% identity in 271 aa overlap CPE1022 GB:PROTEIN_ID BAB80728.1 LENGTH 273 SQ:AASEQ MDKIIIKDFEVFGNHGVFEEEKRLGQKFVLSIELFLDTREAGVTGDLSKSVHYGELAHKVEEEFKKQSYDLIETAAEKLCEFILLEYPLVKKVKVSLKKPWAPILRSLDTVSIEIERGWNEAYLSYGSNIGDKKYYIEEALKEINKAYHTEIIKKSNLIETEPWGYTEQDEFLNGACKIKTLLNPKELIKFLLSIEQKLKRERKIKWGPRTIDLDVIFFNDLISEDEEIILPHPRMHERSFVLEPLNEIAPYKIHPLYRKRVFELLEELNKNK GT:EXON 1|1-273:0| BL:SWS:NREP 1 BL:SWS:REP 1->271|SULD_STRR6|5e-62|44.1|270/270| PROS 206->217|PS00794|HPPK|PDOC00631| SEG 89->99|lvkkvkvslkk| BL:PDB:NREP 1 BL:PDB:REP 1->267|2cg8C|2e-47|42.1|247/248| RP:PDB:NREP 1 RP:PDB:REP 1->267|2cg8A|2e-53|41.4|239/240| RP:PFM:NREP 2 RP:PFM:REP 4->116|PF02152|3e-15|37.8|111/112|FolB| RP:PFM:REP 123->249|PF01288|6e-28|42.9|126/126|HPPK| HM:PFM:NREP 2 HM:PFM:REP 123->249|PF01288|2.6e-45|44.9|127/127|HPPK| HM:PFM:REP 4->117|PF02152|2.7e-33|39.8|113/113|FolB| GO:PFM:NREP 4 GO:PFM GO:0004150|"GO:dihydroneopterin aldolase activity"|PF02152|IPR006157| GO:PFM GO:0006760|"GO:folic acid and derivative metabolic process"|PF02152|IPR006157| GO:PFM GO:0003848|"GO:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"|PF01288|IPR000550| GO:PFM GO:0009396|"GO:folic acid and derivative biosynthetic process"|PF01288|IPR000550| RP:SCP:NREP 2 RP:SCP:REP 1->118|1dhnA|6e-28|30.5|118/121|d.96.1.3| RP:SCP:REP 120->269|1cbkA|1e-49|33.6|149/160|d.58.30.1| HM:SCP:REP 1->120|1dhnA_|2.1e-35|41.7|120/121|d.96.1.3|1/1|Tetrahydrobiopterin biosynthesis enzymes-like| HM:SCP:REP 119->273|1cbkA_|1.7e-52|41.3|155/0|d.58.30.1|1/1|6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK| OP:NHOMO 1078 OP:NHOMOORG 873 OP:PATTERN -------1------------------------------------------------------------ -11-12222222111111---1---211111-11112211122111111112222212----2121122221---111111221111111111111----11111111111111111111----11111111111111111111-211112212111-11---11111-111--1----111-11111111122222222222222222222222222212222222222222222222222222221111112--1--11-1-1111--1--1--1112222222122111111111112222222222222122222222212-111111111-1-22111111--2-12--11222221--221111111-1-1111-----112121221221211111111111-22222222111-1221111111112212-1--111111111111111111111111111111111----------------------11-111111111111111111111111111111111-1111--1111-11111111111111111111111111-111111-11111111111111111---11111111111111111111111111111-12221222112111111111111112111211-11121------11111111111111111-1111111111111111111111111211111111111111111111111111111111111111111121111111112211111111111111111111111111111222121111111111-111--------1111222222112112211111111212111--111111-------------1----------------------11-1111111111 ----11------11111-11111-11111111111111111111--1111111111111111111111111111111-1111111111-11111111111111111-13-4-----------------------------------------------------------3----1-1-71112224431221111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 272 STR:RPRED 99.6 SQ:SECSTR cEEEEEEEEEEEEcccccHHHHHHcEEEEEEEEEEEccHHHHHHTHHHHcccHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHcTTccEEEEEEEETTcccccccccEEEEEEEEcEEEEEEEEEccccHHHHHHHHHHHHHHTTTcEEEEEcccccccccccccccccEEEEEEEEEcccHHHHHHHHHHHHHHTTcccccTTcccccEEEEEEETTccccccccccccTTGGGcHHHHHHHHHHcTTcccTTTcccHHHHHTGGccT# DISOP:02AL 271-273| PSIPRED ccEEEEEEEEEEEEEcccHHHHHcccEEEEEEEEEEccccccccccHHHHccHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHcccccEEEEEEEEccccccccccEEEEEEEEEEEEEEEEEccccccHHHHHHHHHHHHHHccccEEEEEcccEEccccccccccccccEEEEEEEcccHHHHHHHHHHHHHHcccccccccccccEEEEEEEEccEEEcccccEEccHHHHccHHHHHHHHHHccccccccccHHHHHHHHHHHccc //