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Clostridium perfringens str. 13 (cper0)
Gene : folC
DDBJ      :folC         folyl-polyglutamate synthetase
Swiss-Prot:             

Homologs  Archaea  11/68 : Bacteria  857/915 : Eukaryota  181/199 : Viruses  0/175   --->[See Alignment]
c.59.1c.72.2
:440 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->425 1o5zA PDBj 4e-64 35.6 %
:RPS:PDB   21->429 2am1A PDBj 2e-45 10.5 %
:RPS:SCOP  1->296 1o5zA2  c.72.2.2 * 6e-65 37.7 %
:RPS:SCOP  297->427 1o5zA1  c.59.1.2 * 5e-17 26.4 %
:HMM:SCOP  1->296 1o5zA2 c.72.2.2 * 3.4e-105 47.6 %
:HMM:SCOP  297->429 1o5zA1 c.59.1.2 * 1.9e-35 37.0 %
:RPS:PFM   44->203 PF08245 * Mur_ligase_M 2e-13 50.4 %
:HMM:PFM   44->268 PF08245 * Mur_ligase_M 6.1e-24 33.0 176/188  
:HMM:PFM   297->373 PF02875 * Mur_ligase_C 3.9e-13 27.6 76/91  
:BLT:SWISS 3->428 FOLC_BACSU 1e-61 31.6 %
:PROS 42->65|PS01011|FOLYLPOLYGLU_SYNT_1
:PROS 140->155|PS01012|FOLYLPOLYGLU_SYNT_2
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAB81624.1 GT:GENE folC GT:PRODUCT folyl-polyglutamate synthetase GT:DATABASE GIB00075CH01 GT:ORG cper0 GB:ACCESSION GIB00075CH01 GB:LOCATION complement(2196988..2198310) GB:FROM 2196988 GB:TO 2198310 GB:DIRECTION - GB:GENE folC GB:PRODUCT folyl-polyglutamate synthetase GB:NOTE 440 aa, similar to gp:CPFOLC_1 folC gene product from Clostridium perfringens (148 aa); 98.6% identity in 145 aa overlap. 1 putative transmembrane region was found by PSORT CPE1918 GB:PROTEIN_ID BAB81624.1 LENGTH 440 SQ:AASEQ MNYDEAMEYIVTASRFGMNLGLDRIEKVLEFLGNPHKDTKFIHIGGTNGKGSTTAMISSVLREAGFKVGMYTSPYLEEFEERIQINGENINKDDLAILMGDVKKAIDKVMELGYESPTQFEIITALMFYYFSKKKVDYAVLEVGLGGRLDATNVVLPEVVVLTSISLDHMNILGNTIEEIAKEKCGIIKSGVPVISYPQEEKALEVIKERCNELGCNLEVVNTEDIKNIIIDKEKHVQKIEVSLEDEILEIDLGLLGDHQVKNFLVALKTLIKLRNNGVNISNEAIKQGFKKVRWIGRMEVLNENPLVVIDGAHNIDGIRNLRNSIDKYFNFKNITLILGVLGDKQVDEMVEEITRGVDKVVIVEPHSDRAEDIEDLYIKVEKYVKEVFKFKDYKEAYNKAYSFTNDDDLLLICGSLYMVGDMRKAIRNNDNTSLRSIKY GT:EXON 1|1-440:0| BL:SWS:NREP 1 BL:SWS:REP 3->428|FOLC_BACSU|1e-61|31.6|424/430| PROS 42->65|PS01011|FOLYLPOLYGLU_SYNT_1|PDOC00773| PROS 140->155|PS01012|FOLYLPOLYGLU_SYNT_2|PDOC00773| SEG 224->235|edikniiidkek| SEG 244->258|ledeileidlgllgd| SEG 380->396|kvekyvkevfkfkdyke| BL:PDB:NREP 1 BL:PDB:REP 1->425|1o5zA|4e-64|35.6|404/421| RP:PDB:NREP 1 RP:PDB:REP 21->429|2am1A|2e-45|10.5|351/442| RP:PFM:NREP 1 RP:PFM:REP 44->203|PF08245|2e-13|50.4|115/187|Mur_ligase_M| HM:PFM:NREP 2 HM:PFM:REP 44->268|PF08245|6.1e-24|33.0|176/188|Mur_ligase_M| HM:PFM:REP 297->373|PF02875|3.9e-13|27.6|76/91|Mur_ligase_C| GO:PFM:NREP 2 GO:PFM GO:0005524|"GO:ATP binding"|PF08245|IPR013221| GO:PFM GO:0009058|"GO:biosynthetic process"|PF08245|IPR013221| RP:SCP:NREP 2 RP:SCP:REP 1->296|1o5zA2|6e-65|37.7|281/284|c.72.2.2| RP:SCP:REP 297->427|1o5zA1|5e-17|26.4|125/137|c.59.1.2| HM:SCP:REP 1->296|1o5zA2|3.4e-105|47.6|292/296|c.72.2.2|1/1|MurD-like peptide ligases, catalytic domain| HM:SCP:REP 297->429|1o5zA1|1.9e-35|37.0|127/137|c.59.1.2|1/1|MurD-like peptide ligases, peptide-binding domain| OP:NHOMO 1358 OP:NHOMOORG 1049 OP:PATTERN ------------------------21111111-----------------------------111---- 1111111111111111111-11111-1111111111111111111111111111111111111111111111111111111111111111111111---11111111111--------------111111111111111111111211112211111111111111211111111111111112212211121111111111111111111111111111121111111111111111111111111121111111211221212222112113211111112111222222222222222222222222222222222222111211111111111111111111111111111111111111111111212111111111111111111111122211111111111-211111111111211111111111111121111111111111111111111111111111111111111111111111111-11111111111111111111111111111111-1111111111111121111111111111111111111111111111-11111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111-11111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--111111111111111111111111111111111111111111111111111111111111111111111111111111111--------111--1-1---1--------1-------1211111111121 11--111-311-2223322244334323453334333323332232543333433332232222222222222223313322222222-23232232222232223-2-12111-1211-11112-13-8D2-311-1-111-3-111111--11111224212111221133111122A3122232262662122221 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 429 STR:RPRED 97.5 SQ:SECSTR HHHHHHHHHHHTcccccHHTcHHHHHHHHHHHHHHHHccEEEEEEcccccccHHHHHHHHTTTccccccccEEEccTTcccTTHHHHHHHTcTTcHHHHHHHHHHHHHHTTcTTTccccccHHHHHHHHHHHHHcEEEEEccccTTHHHHHHHHHcccEEEEccccccccTTccccHHHHHHHHGGGTTcTTcEEEEEccGGGGGGcccccEEEEEcTTcccTTTccccEEEEEEccccEEEEETTcccEEEEccccHHHHHHHHHHHHHHHHTHHHHTTccHHHHHHHGGGccccccccEEccTcEEEEEcccccHHHHHHHHHHTTcccccccEEEEEEEcHHHHHHGGGccTTTccEEEEEEcTTHHHHHHHHHcTTcEEEEEccccccTHHHHHHHHHHHccTTEEEEEEccccHHHHHHHHHHc########### DISOP:02AL 434-438| PSIPRED ccHHHHHHHHHHcccccccccHHHHHHHHHHHcccccccEEEEEEcccccHHHHHHHHHHHHHccccEEEcccccEEccccEEEEccEEccHHHHHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHccccEEEEEcccccHHHHHEEcccEEEEEEcccHHHHHHccccHHHHHHHHHHHHccccEEEEEcccHHHHHHHHHHHHHEEEEEEEEccccEEEEEEEEccccEEEEEEEccEEEEEEEcccccHHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHccccccEEEEccccEEEEEccccHHHHHHHHHHHHHHcccccEEEEEcccccccHHHHHHHHHHHccEEEEEcccccccccHHHHHHHHHHHcccEEEEccHHHHHHHHHHHcccccEEEEEcHHHHHHHHHHHHHHcccccEEEEcc //