Clostridium perfringens str. 13 (cper0)
Gene : hemA
DDBJ :hemA glutamyl-tRNA reductase
Swiss-Prot:HEM1_CLOPE RecName: Full=Glutamyl-tRNA reductase; Short=GluTR; EC=1.2.1.70;
Homologs Archaea 36/68 : Bacteria 579/915 : Eukaryota 18/199 : Viruses 0/175 --->[See Alignment]
c.2.1
d.58.39
:400 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB 22->70 1yb3A PDBj 8e-04 30.6 %
:BLT:PDB 41->279 1gpjA PDBj 3e-20 32.0 %
:RPS:PDB 90->218 2eggB PDBj 7e-06 10.3 %
:RPS:SCOP 2->152 1gpjA3 d.58.39.1 * 7e-34 25.9 %
:RPS:SCOP 173->279 1omoA c.2.1.13 * 1e-07 16.8 %
:HMM:SCOP 1->152 1gpjA3 d.58.39.1 * 9.4e-35 34.3 %
:HMM:SCOP 173->300 1gpjA2 c.2.1.7 * 6.6e-18 23.4 %
:RPS:PFM 5->149 PF05201 * GlutR_N 1e-20 36.6 %
:RPS:PFM 308->398 PF00745 * GlutR_dimer 2e-04 30.8 %
:HMM:PFM 8->150 PF05201 * GlutR_N 2.8e-41 34.8 141/152
:HMM:PFM 172->289 PF01488 * Shikimate_DH 7.3e-26 33.9 118/135
:HMM:PFM 306->398 PF00745 * GlutR_dimer 1.1e-08 25.8 93/101
:BLT:SWISS 1->400 HEM1_CLOPE 0.0 100.0 %
:PROS 93->116|PS00747|GLUTR
:SEG
SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAB81143.1
GT:GENE hemA
GT:PRODUCT glutamyl-tRNA reductase
GT:DATABASE GIB00075CH01
GT:ORG cper0
GB:ACCESSION GIB00075CH01
GB:LOCATION complement(1694559..1695761)
GB:FROM 1694559
GB:TO 1695761
GB:DIRECTION -
GB:GENE hemA
GB:PRODUCT glutamyl-tRNA reductase
GB:NOTE 400 aa, similar to sp:HEM1_CLOPE GLUTAMYL-TRNA REDUCTASE (EC 1.2.1.-) (GLUTR) from Clostridium perfringens (400 aa); 91% identity in 400 aa overlap CPE1437
GB:PROTEIN_ID BAB81143.1
LENGTH 400
SQ:AASEQ MIGVIGVKRNVDIAIREKLALYPKKHKKYVGELLNSFKEVVILNTCNRTEIYFNCTEEISEDEIFDKIFNVFNWNDDLKKYMFLSKEKRAVTHLMEVICGFHSRILGEDQILGQIKDAYKTAISDNSISSELQKMFEIAIACGKKFKTECKMFEVPVSSVSISINSALLKGCRKFMVLGYGEIGKLAIKHLLSHKVECIYLIVRDKSKASDLEGEIVEVLDFNEKNQVINEVDCIVSCTAAPHTVVRNEDIKTEGDIIHIYDLAVPRDVDKELSEKERVILKDIDEISKIDDKNKKIRKERMEEYKHIVEESIEEFLNWLKIREVSSKIRNIKIRENEICSERIKTFSNKGNGENAKLAERMIKSTADAYVNRAIELLKSEALKGSDSSCAEIIEKIFLT
GT:EXON 1|1-400:0|
SW:ID HEM1_CLOPE
SW:DE RecName: Full=Glutamyl-tRNA reductase; Short=GluTR; EC=1.2.1.70;
SW:GN Name=hemA; OrderedLocusNames=CPE1437;
SW:KW Complete proteome; NADP; Oxidoreductase; Porphyrin biosynthesis.
SW:EXACT T
SW:FUNC +
BL:SWS:NREP 1
BL:SWS:REP 1->400|HEM1_CLOPE|0.0|100.0|400/400|
GO:SWS:NREP 3
GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase|
GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase|
GO:SWS GO:0006779|"GO:porphyrin biosynthetic process"|Porphyrin biosynthesis|
PROS 93->116|PS00747|GLUTR|PDOC00608|
SEG 157->166|vssvsisins|
SEG 280->299|ilkdideiskiddknkkirk|
BL:PDB:NREP 2
BL:PDB:REP 22->70|1yb3A|8e-04|30.6|49/163|
BL:PDB:REP 41->279|1gpjA|3e-20|32.0|228/399|
RP:PDB:NREP 1
RP:PDB:REP 90->218|2eggB|7e-06|10.3|126/166|
RP:PFM:NREP 2
RP:PFM:REP 5->149|PF05201|1e-20|36.6|145/152|GlutR_N|
RP:PFM:REP 308->398|PF00745|2e-04|30.8|91/101|GlutR_dimer|
HM:PFM:NREP 3
HM:PFM:REP 8->150|PF05201|2.8e-41|34.8|141/152|GlutR_N|
HM:PFM:REP 172->289|PF01488|7.3e-26|33.9|118/135|Shikimate_DH|
HM:PFM:REP 306->398|PF00745|1.1e-08|25.8|93/101|GlutR_dimer|
GO:PFM:NREP 8
GO:PFM GO:0008883|"GO:glutamyl-tRNA reductase activity"|PF05201|IPR015895|
GO:PFM GO:0033014|"GO:tetrapyrrole biosynthetic process"|PF05201|IPR015895|
GO:PFM GO:0050661|"GO:NADP or NADPH binding"|PF05201|IPR015895|
GO:PFM GO:0055114|"GO:oxidation reduction"|PF05201|IPR015895|
GO:PFM GO:0008883|"GO:glutamyl-tRNA reductase activity"|PF00745|IPR015896|
GO:PFM GO:0033014|"GO:tetrapyrrole biosynthetic process"|PF00745|IPR015896|
GO:PFM GO:0050661|"GO:NADP or NADPH binding"|PF00745|IPR015896|
GO:PFM GO:0055114|"GO:oxidation reduction"|PF00745|IPR015896|
RP:SCP:NREP 2
RP:SCP:REP 2->152|1gpjA3|7e-34|25.9|139/143|d.58.39.1|
RP:SCP:REP 173->279|1omoA|1e-07|16.8|107/320|c.2.1.13|
HM:SCP:REP 1->152|1gpjA3|9.4e-35|34.3|140/0|d.58.39.1|1/1|Glutamyl tRNA-reductase catalytic, N-terminal domain|
HM:SCP:REP 173->300|1gpjA2|6.6e-18|23.4|128/0|c.2.1.7|1/1|NAD(P)-binding Rossmann-fold domains|
OP:NHOMO 662
OP:NHOMOORG 633
OP:PATTERN ---1--11---------1-1---111111-111111111111111-1-111111-------11----1 121-1111111-1111111-11111111111111111-1111111-1-------------111-11-1-11--------1-1111111-----------11211111111-111111-------11111111111111111---11111111111111111111111111111111111111111111---11111111111111111111111111111111111111111111111111111111111111-------------11---------------------------------------------1---------11111-------1-11-111111211---1-2111111--1111--1-11-11----------------------------------------------------------------------------------------------------------------------------11111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111--11111------11111111111111111-1111111111111111111111111111111111111-111111111111111111111111111---111111111111111111111-----11111111111111111111111111111111111111111111111111111111111111111111111111----------------------------------------------11-----111 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111I111113114-31-1----1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
STR:NPRED 254
STR:RPRED 63.5
SQ:SECSTR #####################EEGGGHHHHHHHHHHccEEEEEEETTEEEEEEEccTTcHHHHHHHTTHT####cTTHHHHHHHHTTccEEEEEEEccTTHHHHHHHHTccEEEEcTTcTTTTGGGGGccEEcHHHHHHTcccEEEEETTEEEEEccHHHHHHHHHHHHTTTTccccccccccHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHccccHHHHHTcTTccEEEEcccGGGHHHHHHHHHTTTcEEEEcccccccHHHHHHHHHHHHT#########################################################################################################################
DISOP:02AL 351-355, 379-388|
PSIPRED cEEEEEEcccccHHHHHHHcccHHHHHHHHHHHHHHHccEEEEEccccEEEEEEEcccccHHHHHHHHHHHccccHHHHHHHHHcccHHHHHHHHHHHccccccccccHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHcccccEEEEEEccHHHHHHHHHHHHccccEEEEEcccHHHHHHHHHHHccEEcHHHHHHHHccccEEEEccccccccccHHHHccccccEEEEEccccccccHHHcccccEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHccc
//
[GTOP]
