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Clostridium perfringens str. 13 (cper0)
Gene : nanJ
DDBJ      :nanJ         exo-alpha-sialidase
Swiss-Prot:             

Homologs  Archaea  0/68 : Bacteria  55/915 : Eukaryota  40/199 : Viruses  0/175   --->[See Alignment]
b.1.2b.18.1b.2.2b.29.1b.68.1
:1173 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   44->180 2v72A PDBj 2e-75 100.0 %
:BLT:PDB   185->367 2v73A PDBj e-102 97.8 %
:BLT:PDB   381->821 2bf6A PDBj e-158 61.5 %
:BLT:PDB   945->1079 2vo8A PDBj 6e-71 99.3 %
:BLT:PDB   1088->1171 1x5gA PDBj 1e-04 25.0 %
:RPS:PDB   48->179 3bn6A PDBj 1e-13 18.1 %
:RPS:PDB   210->356 3b3qE PDBj 6e-08 13.0 %
:RPS:PDB   382->821 2bf6A PDBj 7e-13 53.6 %
:RPS:PDB   1080->1172 2ed8A PDBj 3e-09 20.4 %
:RPS:SCOP  42->179 1gofA2  b.18.1.1 * 5e-21 30.7 %
:RPS:SCOP  203->366 1sliA1  b.29.1.9 * 1e-17 28.2 %
:RPS:SCOP  482->590 1v0eA1  b.68.1.2 * 3e-04 33.0 %
:RPS:SCOP  567->821 1eurA  b.68.1.1 * 3e-51 34.1 %
:RPS:SCOP  945->1079 2vo8A1  b.2.2.2 * 2e-08 99.3 %
:RPS:SCOP  1083->1172 1x5lA1  b.1.2.1 * 7e-10 26.7 %
:HMM:SCOP  44->182 1k3iA2 b.18.1.1 * 4.5e-29 35.3 %
:HMM:SCOP  182->368 2sliA1 b.29.1.9 * 8e-26 26.6 %
:HMM:SCOP  382->825 1so7A_ b.68.1.1 * 6.3e-77 37.6 %
:HMM:SCOP  1087->1172 1fnhA1 b.1.2.1 * 8.1e-11 27.4 %
:RPS:PFM   54->174 PF00754 * F5_F8_type_C 5e-10 36.4 %
:RPS:PFM   192->356 PF02973 * Sialidase 2e-16 37.7 %
:HMM:PFM   199->367 PF02973 * Sialidase 1.1e-44 36.3 168/190  
:HMM:PFM   55->176 PF00754 * F5_F8_type_C 9.6e-26 38.7 119/129  
:HMM:PFM   573->583 PF02012 * BNR 0.0001 72.7 11/12  
:HMM:PFM   637->647 PF02012 * BNR 0.0002 54.5 11/12  
:HMM:PFM   975->998 PF12135 * Sialidase_penC 1.2e-09 45.8 24/25  
:HMM:PFM   1088->1160 PF00041 * fn3 5.7e-09 24.7 73/85  
:BLT:SWISS 1->953 NANH_CLOSE 0.0 52.0 %
:BLT:SWISS 936->1173 OGA_CLOPE 6e-48 43.6 %

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAB80259.1 GT:GENE nanJ GT:PRODUCT exo-alpha-sialidase GT:DATABASE GIB00075CH01 GT:ORG cper0 GB:ACCESSION GIB00075CH01 GB:LOCATION 681830..685351 GB:FROM 681830 GB:TO 685351 GB:DIRECTION + GB:GENE nanJ GB:PRODUCT exo-alpha-sialidase GB:NOTE 1173 aa, similar to sp:NANH_CLOSE SIALIDASE PRECURSOR (EC 3.2.1.18) (NEURAMINIDASE) from Clostridium septicum (1014 aa); 50.9% identity in 953 aa overlap. Putative N-terminal signal sequence was found by PSORT CPE0553 GB:PROTEIN_ID BAB80259.1 LENGTH 1173 SQ:AASEQ MKSKKIIATLVASLVISNMGGYLVKANPNVNHKAVIIEDRQAIIETAIPQSEMTASATSEEGQDPASSAIDGNINTMWHTKWNGSDALPQSLSVNLGKARKVSSIAITPRTSGNNGFITKYEIHAINNGVETLVAEGTWEENNLVKTVTFDSPIDAEEIKITAIQGVGGFASIAELNVYEIKGEVDEIANYGNLKITKEEERLNITGDLEKFSSLDEGTIVTRFNMNDTSIQSLIGLSDGNKANNYFSLYVSGGKVGYELRRQEGNGDFNVHHSADVTFNKGINTLALKIEKGVGAKIFLNGSLVKTVSDPNIKFLNAINLNSGFIGKTDRANGYNEYLFRGNIDFMNIYDKPVSDNYLLRKTGETKAPSEDSLLPDDVYKTQPVELFYPGYLESRGYRIPALETTKKGTVLASIDVRNNGDHDAPNNNIDVGIRRKEVNGEWEEGKVILDYPGKSAAIDTSLMSATIEENGIEKERIFLIVTHFPEGYGFPNTEGGSGYKEIDGKYYFILKDAQNNEYTVREDGIVYNSEGNQTDYVMKNDKTLIQNGEEVGNALLSNSPLKAVGTAHIEMIYSDDDGKTWSEPEDLNPGLKKEWMKFFGTAPGKGIQIKNGEHKGRLVFPIYYTNQNNFQSSAVIYSDDFGETWKLGESPIDTASVSSETVSSGTQLTECQVVEMPNGQLKLFMRNTGSYTKIATSFDGGATWHDEVPEDTSLREPYCQLSVINYSGKINGKDAIIFSNPDASSRVNGSVKVGLINENGTYDNGEPRYEFDWIYNKTVKPGSFAYSCLTELPDGNLGLFYEGEGAGRMAYTEFDLNYLKFNASEDSPSASVQSIEVLDEDLAYNSGEEVSIKVNFNQLVSIIGDRKITLDIGGVDVPLNMVNYEGKSSAIFKGTIPEGINQGNYEIKLKENNTLELNTVYNKVSTFNGLDNTGINVQIGELKTTVGNSTIKVNDEVQVGSAFEAILGIEGLNGDTEVYSAEYLFEYNVEAFILNEITSFNDSLFVKSKEVEPGKVRILVASLGNEIEKDSDLVKVNLTPKISSELEVLGLTTALVGAGDGNTHDLELSSKEVKINEEASGEIVVNPVQNFEIPEINKKNVKLTWNAPITTEGLEGYVIYKDGKKLSEVPAESTEFVVSKLNRHTIYNFKVAAKYSNGELSAKESKTIRTAR GT:EXON 1|1-1173:0| BL:SWS:NREP 2 BL:SWS:REP 1->953|NANH_CLOSE|0.0|52.0|929/1014| BL:SWS:REP 936->1173|OGA_CLOPE|6e-48|43.6|236/1001| BL:PDB:NREP 5 BL:PDB:REP 44->180|2v72A|2e-75|100.0|137/137| BL:PDB:REP 185->367|2v73A|e-102|97.8|183/183| BL:PDB:REP 381->821|2bf6A|e-158|61.5|434/448| BL:PDB:REP 945->1079|2vo8A|6e-71|99.3|135/135| BL:PDB:REP 1088->1171|1x5gA|1e-04|25.0|84/116| RP:PDB:NREP 4 RP:PDB:REP 48->179|3bn6A|1e-13|18.1|127/158| RP:PDB:REP 210->356|3b3qE|6e-08|13.0|138/187| RP:PDB:REP 382->821|2bf6A|7e-13|53.6|433/448| RP:PDB:REP 1080->1172|2ed8A|3e-09|20.4|93/106| RP:PFM:NREP 2 RP:PFM:REP 54->174|PF00754|5e-10|36.4|118/126|F5_F8_type_C| RP:PFM:REP 192->356|PF02973|2e-16|37.7|162/183|Sialidase| HM:PFM:NREP 6 HM:PFM:REP 199->367|PF02973|1.1e-44|36.3|168/190|Sialidase| HM:PFM:REP 55->176|PF00754|9.6e-26|38.7|119/129|F5_F8_type_C| HM:PFM:REP 573->583|PF02012|0.0001|72.7|11/12|BNR| HM:PFM:REP 637->647|PF02012|0.0002|54.5|11/12|BNR| HM:PFM:REP 975->998|PF12135|1.2e-09|45.8|24/25|Sialidase_penC| HM:PFM:REP 1088->1160|PF00041|5.7e-09|24.7|73/85|fn3| GO:PFM:NREP 3 GO:PFM GO:0007155|"GO:cell adhesion"|PF00754|IPR000421| GO:PFM GO:0004308|"GO:exo-alpha-sialidase activity"|PF02973|IPR004124| GO:PFM GO:0005975|"GO:carbohydrate metabolic process"|PF02973|IPR004124| RP:SCP:NREP 6 RP:SCP:REP 42->179|1gofA2|5e-21|30.7|137/150|b.18.1.1| RP:SCP:REP 203->366|1sliA1|1e-17|28.2|163/196|b.29.1.9| RP:SCP:REP 482->590|1v0eA1|3e-04|33.0|97/516|b.68.1.2| RP:SCP:REP 567->821|1eurA|3e-51|34.1|226/361|b.68.1.1| RP:SCP:REP 945->1079|2vo8A1|2e-08|99.3|135/135|b.2.2.2| RP:SCP:REP 1083->1172|1x5lA1|7e-10|26.7|90/98|b.1.2.1| HM:SCP:REP 44->182|1k3iA2|4.5e-29|35.3|139/0|b.18.1.1|1/1|Galactose-binding domain-like| HM:SCP:REP 182->368|2sliA1|8e-26|26.6|184/0|b.29.1.9|1/1|Concanavalin A-like lectins/glucanases| HM:SCP:REP 382->825|1so7A_|6.3e-77|37.6|343/0|b.68.1.1|1/1|Sialidases| HM:SCP:REP 1087->1172|1fnhA1|8.1e-11|27.4|84/0|b.1.2.1|1/1|Fibronectin type III| OP:NHOMO 218 OP:NHOMOORG 95 OP:PATTERN -------------------------------------------------------------------- --1-2-2-111-1---------------------------------2-----221--------3--2331-----2------------6631-111----1------1-6-----------------------------------------------------------------------------------------1------1------------------------1-----------------------------------------------111-111---33344334243-------------------------------------------B93-----------------------------2-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------1------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------4 ------2-------------11-1-1---------------------1--2212----1---------------------------------------------------O11--4-1--1-1-1--21851-11----1--111111111-13---1-----1----------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 1109 STR:RPRED 94.5 SQ:SECSTR ########################HHHHHHHccccccTTHGGGccccccGGGEEEcccccGGGcGGccTTcccccccEEcccccTcccTccEEEEEEEEEEEEEEEEEcEEETEEEEEEEEEEEEEcccccccccEEccccccccEEEEEEEEEEEEEEEEEEEEEEcccccEEEEEEEEEEccccccEEEEEEEEccGGGcEEcGGGGTccccccEEEEEEEEEEcccEcEEEEEEEEcTTcccEEEEEEETTEEEEEEEcEcccccEEEEcccccccccccEEEEEEEETTEEEEEEccccccEEEccccccccccccEEEEEEccTTTTcccccccccEEEEEEEETTEEHHHHHHTTcTTGGc###HHTTccTTccccccEEEEcTTGGGccEEEEEEEEEcTTccEEEEEEEETTccccTTcccEEEEEEEccTTccccccEEEEcccTTcEEEEEEEEEcTTTccEEEEEEEEcTTccTTTccccccEEEETTEEEEEEEcTTccEEEEETTEEcGGGcccEcTTccEEEEEEcTTcEEEETTEEEEETTccccccEEccccEEEEEEEccTTccccccEEcHHHHccTTcccEEEccEEcEEccccTTTTcEEEEEEEEcTTccEEEEEEEEccTTcccEEcccTTTTEEcTTcccccTTcEEEEEEEEcTTccEEEEEEEcccEEEEEEEccTTcccccccEEEEEEEccccccEEEEcccccTTccEEEEEEEcccccEEEEEEEEEEEEEEEcTTccEEEEEEEEEEEEEEEEEcccEEEEEcTTccEEEEEcccccccEEEEEEcHHHHTEEHHHHTcccccEEc####ccEEEcTTcEEEEEEEEccccccccccEEEEEEEEEEccc#cTTcEEEEEEEE##EccTTcccEEEEE##############################cccccccccEEEEEEcccEEETTccEEEEEEEEcccTTccEEEEEEEEEccTTTEEEEEEEEccTTEEEEEEEEETTEEEEEEEEccccccTTcEEEEEEEEEcccEEEEEEEEEEEEEEEEEcccccccccccccccGGGccccccccccEEEEEEcccTTEEEEEEEcccccccccEEEEETTTccEEEEEEccccEEEEcccTTcEEEEEEEEEccccEEEEcccEEEEccT DISOP:02AL 1-4, 37-46, 57-62, 829-830, 832-833, 1074-1084, 1167-1168| PSIPRED ccccEEEEEEEccEEEEEcccEEEEEcHHHccEEEEEcccccccHHHcccccEEEEEccccccccEEEEEEcccccEEEEcccccccccEEEEEEcccEEEEEEEEEEEccccccccEEEEEEEEEccccEEEEEEEEccccccEEEEEccccccEEEEEEEEEccccccEEEEEEEEEcccccccccccccEEEEccccccccccHHHHHccccccEEEEEEEEcccccEEEEEEEccccccccEEEEEEEccEEEEEEEcccccEEEcccEEEEEEEEccEEEEEEEEEcccEEEEEEccEEEEEEcccccEEcccccccEEEcccEEEccccEEEEcccEEEEEEEEcccccHHHHHEEEEEEEEEcccccccccccccccEEEEEcccccccEEEccEEEEEcccEEEEEEEEcccccccccccccEEEEEEEccccEEcccEEEEcccccccccccccccEEEEEccccccEEEEEEEEccccEEEEccccccccccccccEEEEEEEEcccEEEEEcccEEEcccccccEEEEccccEEEEccEEEEEEEEccccEEEccccEEEEEEEEcccEEEcccEEccccccccccEEEEccccEEEEEcccccccEEEEEEEEEcccccEEEEEEEEcccccEEEEccccccccccccccccccccccccEEEEEcccEEEEEEEcccccEEEEEEcccccccccccccccccccccccEEEEEEcccccccEEEEEEcccccccccEEEEEEEEEccEEEEcccEEcccccccccEEEcccccccEEEEEccccEEEEEEEcccccEEEEEEEHHHHHcccccccccccccccEEcccEEEcccccEEEEEEEEcccccccccEEEEEEEccEEEccEEEEEccccccccccEEEEEcccccEEEEEccccccEEEcccccEEEcccccEEEEEEEEEEEEcccEEEEEEEcEEEEcccEEEEEEEcccccccEEEEEEcccccccccccccccccccccEEEEEEccccccEEEEEccccccccccccEEEEEEEccEEEEcEEEEEEEEEccccccEEEEEcccccEEEEEccccccccccccccccEEEEEcccEEEEEEEcccccccEEEEEEEEcccEEEEEcccccEEEEcccccccEEEEEEEEEEccccccccccEEEEEcc //