[GTOP] [HELP] [ORGANISMS] [SEARCH] [SUMMARY]
Clostridium perfringens str. 13 (cper0)
Gene : topA.1
DDBJ      :topA         DNA topoisomerase I
Swiss-Prot:             

Homologs  Archaea  66/68 : Bacteria  895/915 : Eukaryota  111/199 : Viruses  1/175   --->[See Alignment]
e.10.1g.41.3g.54.1
:700 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   4->609 2gaiA PDBj e-115 44.0 %
:RPS:PDB   2->569 1eclA PDBj e-153 42.7 %
:RPS:PDB   617->683 3a43A PDBj 1e-10 18.0 %
:RPS:SCOP  2->548 1cy0A  e.10.1.1 * e-142 43.5 %
:RPS:SCOP  559->620 1yuaA1  g.41.3.3 * 3e-12 22.6 %
:RPS:SCOP  617->667 1nltA3  g.54.1.1 * 2e-08 17.6 %
:RPS:SCOP  651->683 1yuaA1  g.41.3.3 * 3e-05 17.6 %
:HMM:SCOP  2->588 1mw9X_ e.10.1.1 * 2.3e-201 46.7 %
:RPS:PFM   4->98 PF01751 * Toprim 4e-10 42.5 %
:RPS:PFM   127->541 PF01131 * Topoisom_bac 3e-89 47.5 %
:RPS:PFM   577->609 PF01396 * zf-C4_Topoisom 3e-09 54.5 %
:RPS:PFM   617->646 PF01396 * zf-C4_Topoisom 5e-07 50.0 %
:HMM:PFM   128->545 PF01131 * Topoisom_bac 6.5e-135 45.8 393/404  
:HMM:PFM   576->609 PF01396 * zf-C4_Topoisom 3e-15 47.1 34/39  
:HMM:PFM   616->651 PF01396 * zf-C4_Topoisom 1.2e-17 60.0 35/39  
:HMM:PFM   655->691 PF01396 * zf-C4_Topoisom 3.2e-08 41.7 36/39  
:HMM:PFM   4->111 PF01751 * Toprim 9.7e-32 48.4 95/96  
:BLT:SWISS 1->678 TOP1_BACSU 0.0 55.4 %
:PROS 279->302|PS00396|TOPOISOMERASE_I_PROK
:REPEAT 3|564->604|606->644|646->683
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAB81408.1 GT:GENE topA.1 GT:PRODUCT DNA topoisomerase I GT:DATABASE GIB00075CH01 GT:ORG cper0 GB:ACCESSION GIB00075CH01 GB:LOCATION complement(1980439..1982541) GB:FROM 1980439 GB:TO 1982541 GB:DIRECTION - GB:GENE topA GB:PRODUCT DNA topoisomerase I GB:NOTE 700 aa, similar to sp:TOP1_BACSU DNA TOPOISOMERASE I (EC 5.99.1.2) (OMEGA-PROTEIN) (RELAXING ENZYME) (UNTWISTING ENZYME) (SWIVELASE) from Bacillus subtilis (691 aa); 53.7% identity in 678 aa overlap CPE1702 GB:PROTEIN_ID BAB81408.1 LENGTH 700 SQ:AASEQ MGQKLVIVESPAKAKTIEKYLGKNYVVEASMGHVRDLPKSQLGVDIENEYNPKYITIRGKGELLSKLRKLAKKSDKIYLATDPDREGEAISWHLANVLKIDENENCRIEFNEITKDAVKNSIKHPRKINCNLVDAQQARRVLDRLVGYEISPLLWRNVKWGLSAGRVQSAALKLICDREEEIKKFNPEEYWTVDVKLKKGKKSFPVKLTTKNKKKIEIKNKEQADQIIDELKENEYIVSKIKKGTKNKNPLAPFTTSTLQQEASKKLNFMTKKTMSVAQQLYEGVEVKKFGTVGLITYMRTDSVRISKEAQEKALNFIDETYGKEYVPEESRVYKGKKNIQDAHEAIRPTYVEITPEIAKANLSNDQYKLYALIWKRFIASQMATCILNTNSLEIKNGDYTLRASGSTIKFDGFMKVYEYISGEEEESVLLPELEENEVLKEESIEGKQHFTQPPARYSEAAFVKLLEEKGIGRPSTYVPTISTLISRKYVDREKKILIPTELGFIVNDILSNYFKQIVDTDFTAEMEVKLDNVEAGKESWTHIVDEFFTPLKEDIEKAEKEISKVIIEDKVSDVPCDKCGRLMVIKHGRFGDFLACPGYPECQNTKPIVEEVDANCPLCGGKILVKRSKKGNRFYGCSNYPECNFVSWYEPTNEKCPECGSYMVKRYSKSKGEYLQCSDKECKYEKIIEKNNDENNSEK GT:EXON 1|1-700:0| BL:SWS:NREP 1 BL:SWS:REP 1->678|TOP1_BACSU|0.0|55.4|675/691| PROS 279->302|PS00396|TOPOISOMERASE_I_PROK|PDOC00333| NREPEAT 1 REPEAT 3|564->604|606->644|646->683| SEG 63->76|llsklrklakksdk| SEG 209->222|ttknkkkieiknke| SEG 424->446|eeeesvllpeleenevlkeesie| SEG 684->699|kyekiieknndennse| BL:PDB:NREP 1 BL:PDB:REP 4->609|2gaiA|e-115|44.0|564/581| RP:PDB:NREP 2 RP:PDB:REP 2->569|1eclA|e-153|42.7|543/552| RP:PDB:REP 617->683|3a43A|1e-10|18.0|61/138| RP:PFM:NREP 4 RP:PFM:REP 4->98|PF01751|4e-10|42.5|87/110|Toprim| RP:PFM:REP 127->541|PF01131|3e-89|47.5|400/407|Topoisom_bac| RP:PFM:REP 577->609|PF01396|3e-09|54.5|33/39|zf-C4_Topoisom| RP:PFM:REP 617->646|PF01396|5e-07|50.0|29/39|zf-C4_Topoisom| HM:PFM:NREP 5 HM:PFM:REP 128->545|PF01131|6.5e-135|45.8|393/404|Topoisom_bac| HM:PFM:REP 576->609|PF01396|3e-15|47.1|34/39|zf-C4_Topoisom| HM:PFM:REP 616->651|PF01396|1.2e-17|60.0|35/39|zf-C4_Topoisom| HM:PFM:REP 655->691|PF01396|3.2e-08|41.7|36/39|zf-C4_Topoisom| HM:PFM:REP 4->111|PF01751|9.7e-32|48.4|95/96|Toprim| GO:PFM:NREP 12 GO:PFM GO:0003677|"GO:DNA binding"|PF01131|IPR013497| GO:PFM GO:0003916|"GO:DNA topoisomerase activity"|PF01131|IPR013497| GO:PFM GO:0005694|"GO:chromosome"|PF01131|IPR013497| GO:PFM GO:0006265|"GO:DNA topological change"|PF01131|IPR013497| GO:PFM GO:0003677|"GO:DNA binding"|PF01396|IPR013498| GO:PFM GO:0003916|"GO:DNA topoisomerase activity"|PF01396|IPR013498| GO:PFM GO:0005694|"GO:chromosome"|PF01396|IPR013498| GO:PFM GO:0006265|"GO:DNA topological change"|PF01396|IPR013498| GO:PFM GO:0003677|"GO:DNA binding"|PF01396|IPR013498| GO:PFM GO:0003916|"GO:DNA topoisomerase activity"|PF01396|IPR013498| GO:PFM GO:0005694|"GO:chromosome"|PF01396|IPR013498| GO:PFM GO:0006265|"GO:DNA topological change"|PF01396|IPR013498| RP:SCP:NREP 4 RP:SCP:REP 2->548|1cy0A|e-142|43.5|526/534|e.10.1.1| RP:SCP:REP 559->620|1yuaA1|3e-12|22.6|62/65|g.41.3.3| RP:SCP:REP 617->667|1nltA3|2e-08|17.6|51/74|g.54.1.1| RP:SCP:REP 651->683|1yuaA1|3e-05|17.6|32/65|g.41.3.3| HM:SCP:REP 2->588|1mw9X_|2.3e-201|46.7|561/0|e.10.1.1|1/1|Prokaryotic type I DNA topoisomerase| OP:NHOMO 1667 OP:NHOMOORG 1073 OP:PATTERN 333333323333333322221222111111111112211111111111122222222222211123-- 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111123-322333311341--1131112221211111111111111111111111111111111111132321111111111111111222211111111111111111222112234344333333334331222243413422221222223332222221232222222222211111211111211112211121111141122111111111111111111111121111111111111123333222333333326333333131221222133341211121122112111111111111111111111111111111111111-111121121121111111111111111111111111111111111111111111111111111111111111111111111111111111----1111111111111111111111141111211111-31211111111111112111211111121311112111221122221111111111111111111111111211111232121111221212322313232224343233322222232231-111121--11122233312222222222-2222222222222222222223322443222222232332322521222112-233233333533--1111111111111112221222232222322211211111111122222221122311111111111111232233333433331111111111211111211111111111111111111111-111-111111111111111211212122211- 1--111--4311111-----111-----1-----------------1-1---1--1----1--11111111-1111----1111------2----111111-11-1-111412112-111--1-23-3-7G2-32111--1-22-----12---13222115-42--1-1222-21111G111113113113311---- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- STR:NPRED 682 STR:RPRED 97.4 SQ:SECSTR #ccEEEEEccHHHHHHHHTTccTTEEEEEcccccEEcccHHHcEETTTTTEEccEEcTTTHHHHHHHHHHHHHccEEEEcccccHHHHHHHHHHHHHHcccGGGEEEcccccccHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHTcTTccccTTHHHHHHHHHHHHHHHHTccccEEEEEEEEEcTTccEEEEEEEEETTEEcccccHHHHHHHHHHHHHccEEEEEEEEEEEEEcccccccHHHHHHHHHHHHcccHHHHHHHHHHHHHTTcTTGcGGcTcccccccccccccHHHHHHHHHHHHHHTcGGGcccccccccccccccccccccccccTTccGGGccccccHHHHHHHHHHHHHHHHHTcccEEEEEEEEEEEETTEEEEEEEEEEEEcGGGGTccccccccccccccccccTTcEEEEEEEEEEEEEccccccccHHHHHHHHHHTTcccTTTHHHHHHHHHHTTcEEEETTEEEEcHHHHHHHHHHHHHcHHHHcHHHHHHHHHHHHHHHTTcccHHHHHHHHHHHHHHHHHHHTccGGGTcccccccccccGGGTcccEEEEEEEEEcccTTTcccHHHHHHHHHHcEEEEEcccEEcHHHHHTTcccEEEccHHHHHHHHHHHHHHHHHHHHcTcTTTTccTTccHHHHTTTHHHH################# DISOP:02AL 244-247, 330-341, 684-700| PSIPRED cccEEEEEEccHHHHHHHHHcccccEEEEEEccEEEcccccccccHHHcccccEEccccHHHHHHHHHHHHHHccEEEEEccccccHHHHHHHHHHHHccccccEEEEEEEcccHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccHHHHHHHHHHHHHHHHccccccEEEEEEEEEccccEEEEEEEEccccccccccHHHHHHHHHHHHcccEEEEEEEEEEEEEcccccccHHHHHHHHHHHHcccHHHHHHHHHHHHccccccccccEEEccccccccEEccHHHHHHHHHHHHHHHHHHHcccccccccccccccccccccccccccccHHHHHHcccHHHHHHHHHHHHHHHHHHccccEEEEEEEEEEEccEEEEEEEEEEEEccHHHHcccccccccccccccccccccEEEEEEEEEEccEEcccccccHHHHHHHHHHcccccccccHHHHHHHHHcccEEEEccEEEEcHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccHHccccEEEEEccccccccccccccccccccccccccccccccccEEEEEEcccccEEEEEcccccccccccccccccccccccccEEEEEEccccEEEEccccccccccccccccccccccc //