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Desulfotomaculum reducens MI-1 (dred0)
Gene : ABO48792.1
DDBJ      :             DNA-directed RNA polymerase, alpha subunit
Swiss-Prot:RPOA_DESRM   RecName: Full=DNA-directed RNA polymerase subunit alpha;         Short=RNAP subunit alpha;         EC=2.7.7.6;AltName: Full=Transcriptase subunit alpha;AltName: Full=RNA polymerase subunit alpha;

Homologs  Archaea  0/68 : Bacteria  910/915 : Eukaryota  10/199 : Viruses  0/175   --->[See Alignment]
a.60.3d.181.1d.74.3
:315 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   15->224 1ynjB PDBj 1e-58 53.1 %
:BLT:PDB   240->311 3gfkB PDBj 5e-29 80.6 %
:RPS:PDB   1->229 3dxjA PDBj 4e-63 49.1 %
:RPS:PDB   244->312 1doqA PDBj 8e-21 31.9 %
:RPS:SCOP  2->67 1bdfA1  d.74.3.1 * 2e-06 42.4 %
:RPS:SCOP  50->171 1bdfA2  d.181.1.1 * 2e-34 39.2 %
:RPS:SCOP  244->312 1doqA  a.60.3.1 * 3e-21 31.9 %
:HMM:SCOP  50->171 1i6vA2 d.181.1.1 * 4.1e-46 58.7 %
:HMM:SCOP  245->316 1cooA_ a.60.3.1 * 1.6e-23 56.9 %
:RPS:PFM   25->221 PF01193 * RNA_pol_L 1e-29 49.5 %
:RPS:PFM   239->299 PF03118 * RNA_pol_A_CTD 6e-16 59.0 %
:HMM:PFM   240->305 PF03118 * RNA_pol_A_CTD 1.6e-30 59.1 66/67  
:HMM:PFM   26->224 PF01193 * RNA_pol_L 3e-27 50.6 83/86  
:HMM:PFM   217->262 PF09059 * TyeA 0.00059 21.7 46/87  
:BLT:SWISS 1->315 RPOA_DESRM e-170 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABO48792.1 GT:GENE ABO48792.1 GT:PRODUCT DNA-directed RNA polymerase, alpha subunit GT:DATABASE GIB00494CH01 GT:ORG dred0 GB:ACCESSION GIB00494CH01 GB:LOCATION 245294..246241 GB:FROM 245294 GB:TO 246241 GB:DIRECTION + GB:PRODUCT DNA-directed RNA polymerase, alpha subunit GB:NOTE KEGG: dsy:DSY0499 hypothetical protein TIGRFAM: DNA-directed RNA polymerase, alpha subunit PFAM: RNA polymerase, alpha subunit domain protein; RNA polymerase, dimerisation; RNA polymerase, insert SMART: RNA polymerase, RpoA/D/Rpb3-type GB:PROTEIN_ID ABO48792.1 GB:DB_XREF GI:134050821 InterPro:IPR011260 InterPro:IPR011261 InterPro:IPR011262 InterPro:IPR011263 InterPro:IPR011773 LENGTH 315 SQ:AASEQ MLEIEKPKIEIVEQSEDNTYGKFVVEPLERGYGITLGNSLRRILLSSLPGAAVTSVKIEGVLHEFATVPGVQEDVTDIILNLKNLCLKIHSDEEKVLRVEAQTEGPVTAGDIIHDADVEILNPDLHLATLDTGGRLFMEISVNKGRGYSSAEKNKKGEHIIGVIPIDSIYTPVRRVNYNVENTRVGQITDYDKLTLEVWTNGSIRPDEATSLSAKILSEHLRLFIGLTETVNDVEIMVEKEEEQKDKILEMTIEELDMSVRSYNCLKRAGINTVEELIQRNEEDMMKVRNLGKKSLEEVINKLHELGLSLRQEDE GT:EXON 1|1-315:0| SW:ID RPOA_DESRM SW:DE RecName: Full=DNA-directed RNA polymerase subunit alpha; Short=RNAP subunit alpha; EC=2.7.7.6;AltName: Full=Transcriptase subunit alpha;AltName: Full=RNA polymerase subunit alpha; SW:GN Name=rpoA; OrderedLocusNames=Dred_0243; SW:KW Complete proteome; DNA-directed RNA polymerase;Nucleotidyltransferase; Transcription; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->315|RPOA_DESRM|e-170|100.0|315/315| GO:SWS:NREP 4 GO:SWS GO:0003899|"GO:DNA-directed RNA polymerase activity"|DNA-directed RNA polymerase| GO:SWS GO:0016779|"GO:nucleotidyltransferase activity"|Nucleotidyltransferase| GO:SWS GO:0006350|"GO:transcription"|Transcription| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| SEG 78->89|iilnlknlclki| BL:PDB:NREP 2 BL:PDB:REP 15->224|1ynjB|1e-58|53.1|209/225| BL:PDB:REP 240->311|3gfkB|5e-29|80.6|72/76| RP:PDB:NREP 2 RP:PDB:REP 1->229|3dxjA|4e-63|49.1|228/231| RP:PDB:REP 244->312|1doqA|8e-21|31.9|69/69| RP:PFM:NREP 2 RP:PFM:REP 25->221|PF01193|1e-29|49.5|194/207|RNA_pol_L| RP:PFM:REP 239->299|PF03118|6e-16|59.0|61/67|RNA_pol_A_CTD| HM:PFM:NREP 3 HM:PFM:REP 240->305|PF03118|1.6e-30|59.1|66/67|RNA_pol_A_CTD| HM:PFM:REP 26->224|PF01193|3e-27|50.6|83/86|RNA_pol_L| HM:PFM:REP 217->262|PF09059|0.00059|21.7|46/87|TyeA| GO:PFM:NREP 6 GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF01193|IPR011261| GO:PFM GO:0006350|"GO:transcription"|PF01193|IPR011261| GO:PFM GO:0046983|"GO:protein dimerization activity"|PF01193|IPR011261| GO:PFM GO:0003677|"GO:DNA binding"|PF03118|IPR011260| GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF03118|IPR011260| GO:PFM GO:0006350|"GO:transcription"|PF03118|IPR011260| RP:SCP:NREP 3 RP:SCP:REP 2->67|1bdfA1|2e-06|42.4|65/105|d.74.3.1| RP:SCP:REP 50->171|1bdfA2|2e-34|39.2|120/121|d.181.1.1| RP:SCP:REP 244->312|1doqA|3e-21|31.9|69/69|a.60.3.1| HM:SCP:REP 50->171|1i6vA2|4.1e-46|58.7|121/0|d.181.1.1|1/1|Insert subdomain of RNA polymerase alpha subunit| HM:SCP:REP 245->316|1cooA_|1.6e-23|56.9|72/0|a.60.3.1|1/1|C-terminal domain of RNA polymerase alpha subunit| OP:NHOMO 938 OP:NHOMOORG 920 OP:PATTERN -------------------------------------------------------------------- 1111111111111111111-11111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112222222221111111111111111111111111111111111112111111111111111111-11111111111111111111111111111111 --------------1-----------------------------------------------------------------------------------------------------------------------------------------------1----------------1-1------12111--1------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 312 STR:RPRED 99.0 SQ:SECSTR cccccccccEEEEEEccccEEEEEEEEEcTTHHHHHHHHHHHHHHTTcEEEEEEEEEETTcccTTcccTTccccHHHHHHHHHTccEEEccTTccEEEEEEcccEEEcGGGccccTTEEEccTTcccEEEcTTccEEEEEEEEEEEcEEcTTTcccccccTTcEEccEEcccEEEEEEEEcccccccccccEEEEEEEEEcccccHHHHHHHHHHHHHHHHHTTccccccccccEEEEEEEEEcccHHHEEEHHHHHHHHHHHHHHHHTTcccHHHHHHHccccHHTcHHHHHHTTTGGHHHHHHHcccccc### DISOP:02AL 1-1,231-248,313-316| PSIPRED ccccccccEEEEEEccccEEEEEEEEcccccHHHHHHHHHHHHHHHcccccEEEEEEEccEEccccccccccccHHHHHHHHHccEEEEEccccEEEEEEEEccEEEEHHHEEcccccEEEcccEEEEEEccccEEEEEEEEEEccccccccccccccccccEEEEccccccEEEEEEEEEEcccccccccEEEEEEEEEcccccHHHHHHHHHHHHHHHHHHHHccccccccccccccccccccHHHHcccHHHHcccHHHHHHHHHcccccHHHHHHccHHHHHHccccccccHHHHHHHHHHcccccccccc //