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Desulfotomaculum reducens MI-1 (dred0)
Gene : ABO48837.1
DDBJ      :             3-isopropylmalate dehydrogenase
Swiss-Prot:             

Homologs  Archaea  58/68 : Bacteria  772/915 : Eukaryota  188/199 : Viruses  0/175   --->[See Alignment]
c.77.1
:356 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   3->355 1v5bB PDBj e-112 59.3 %
:RPS:PDB   2->355 1cnzA PDBj e-122 51.6 %
:RPS:SCOP  1->355 1a05A  c.77.1.1 * 2e-98 56.5 %
:HMM:SCOP  1->358 1a05A_ c.77.1.1 * 3.3e-133 49.6 %
:RPS:PFM   4->334 PF00180 * Iso_dh 3e-72 50.0 %
:HMM:PFM   3->351 PF00180 * Iso_dh 3.6e-143 59.8 343/347  
:BLT:SWISS 2->355 LEU3_CARHZ e-120 60.7 %
:PROS 243->262|PS00470|IDH_IMDH
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABO48837.1 GT:GENE ABO48837.1 GT:PRODUCT 3-isopropylmalate dehydrogenase GT:DATABASE GIB00494CH01 GT:ORG dred0 GB:ACCESSION GIB00494CH01 GB:LOCATION 298047..299117 GB:FROM 298047 GB:TO 299117 GB:DIRECTION + GB:PRODUCT 3-isopropylmalate dehydrogenase GB:NOTE KEGG: swo:Swol_2140 3-isopropylmalate dehydrogenase TIGRFAM: 3-isopropylmalate dehydrogenase PFAM: isocitrate/isopropylmalate dehydrogenase GB:PROTEIN_ID ABO48837.1 GB:DB_XREF GI:134050866 InterPro:IPR001804 InterPro:IPR004429 LENGTH 356 SQ:AASEQ MYKVALLPGDGIGPEIVPQAVRVLQAIGEKYKREFSFQTALIGGAAYDATGHPLPEETLAVCRNSDAILLGAVGGPKWDNLEPQLRPERGALLPLRKKLGLYANVRPASVNSALAEASPLKEELVSGLDILIIRELTGGLYFGQKHREDIPGGGQKAVETLEYTTEEVERVARLGFEMASKRNKKLMSVDKANVLESSRLWREVVEEVAKDYPDVELSHMYVDNCAMQLVRYPKQFDVMVTENMFGDILTDLASQLTGSIGMLPSASLGGEVALYEPIHGSAPDIAGKNLANPIATILSAAMMLRISFGLETEAAAIEQAVAKVLDQGYRTGDIMQPGKTKVGTVEVTDAIIKALG GT:EXON 1|1-356:0| BL:SWS:NREP 1 BL:SWS:REP 2->355|LEU3_CARHZ|e-120|60.7|354/374| PROS 243->262|PS00470|IDH_IMDH|PDOC00389| SEG 158->171|vetleytteeverv| BL:PDB:NREP 1 BL:PDB:REP 3->355|1v5bB|e-112|59.3|351/357| RP:PDB:NREP 1 RP:PDB:REP 2->355|1cnzA|e-122|51.6|353/363| RP:PFM:NREP 1 RP:PFM:REP 4->334|PF00180|3e-72|50.0|318/338|Iso_dh| HM:PFM:NREP 1 HM:PFM:REP 3->351|PF00180|3.6e-143|59.8|343/347|Iso_dh| GO:PFM:NREP 4 GO:PFM GO:0000287|"GO:magnesium ion binding"|PF00180|IPR001804| GO:PFM GO:0016616|"GO:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"|PF00180|IPR001804| GO:PFM GO:0051287|"GO:NAD or NADH binding"|PF00180|IPR001804| GO:PFM GO:0055114|"GO:oxidation reduction"|PF00180|IPR001804| RP:SCP:NREP 1 RP:SCP:REP 1->355|1a05A|2e-98|56.5|354/357|c.77.1.1| HM:SCP:REP 1->358|1a05A_|3.3e-133|49.6|357/0|c.77.1.1|1/1|Isocitrate/Isopropylmalate dehydrogenase-like| OP:NHOMO 2321 OP:NHOMOORG 1018 OP:PATTERN 11-2--2222222222-22222222--222222222222222222222323332221-1--2112-22 4443111111111221111-111113111111133322531111211-1111121111--111-13411111111111-22-322121111211---11--2-1111131--------------111111111121222222224321321122211111111112222322122222122222333311131222222222322222232222222221322--11111121-1111111111111111111-------1------------12-221-------222-1111111111-------------222222222-23-21111111111122111---2-11-311222211212-221112--32221111-1--1117441132222111111111111-23422433222-3222225424221111131241342112222222253322221111111111111111111111111111111131113543445554433333554533331333745532222553444444674333222212111111122223312311121222222-111111121111124131111111111-1111111111211122221221312312222222222222222222-1-2432-11--121221112221211122-2212211222212222222233111211111111111111111122211121-122222222222111111111222223232111113-111-2112222221112111222233232232323431-1--1---111111111111111222222222222222211112222-------------------------------------22--1-111212 ----224-1---3347867778688876645555555555455544546777896665444433444434425442433344444424-46484456564416667-3235583333223127233232Ed6-5452223823641332331166323536424333A3794453333191112374986931121111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 356 STR:RPRED 100.0 SQ:SECSTR EEEEEEEEEcTTHHHHHHHHHHHHHHHHHHHTccEEEEEcccTHHHHHHHcccccHHHHHHHHTccEEEEEEcccGGGTTccGGGcTTHHHHHHHHHHHTccEEEEEEEccTTcGGGccccHHHHHccEEEEEEEcccGGGTccccEEEccGGGcEEEccccccHHHHHHHHHHHHHHHHTTTcEEEEEEcTTTcHHHHHHHHHHHHHHTTcTTcEEEEEEHHHHHHHHHHcGGGccEEEEcHHHHHHHHHHHHHHHTcGGGcEEEEEcTTcEEEEEcccccGGGTTTTccccHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHTTcccGGGTcTTTTcccHHHHHHHHHHHHT PSIPRED cEEEEEEccccccHHHHHHHHHHHHHHHccccccEEEEEEEccHHHHHHHcccccHHHHHHHHHccEEEEccccccccccccccccccccHHHHHHHHHccEEEEEEEEEEcccccccccccccccccEEEEEEccccccccccccEEEcccccEEEEEEEEccHHHHHHHHHHHHHHHHHcccEEEEEEcHHHHHHcHHHHHHHHHHHHHccccEEEEEEHHHHHHHHHHccccccEEEEcccHHHHHHHHHHHHcccHHHccccccccccEEEEEcccccccccccccccHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHcccccHHHcccccccccHHHHHHHHHHHHc //