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Desulfotomaculum reducens MI-1 (dred0)
Gene : ABO49212.1
DDBJ      :             UDP-N-acetylmuramoylalanine--D-glutamate ligase
Swiss-Prot:MURD_DESRM   RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase;         EC=6.3.2.9;AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase;AltName: Full=D-glutamic acid-adding enzyme;

Homologs  Archaea  0/68 : Bacteria  862/915 : Eukaryota  7/199 : Viruses  0/175   --->[See Alignment]
c.5.1c.59.1c.72.2c.78.2
:456 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->450 2uagA PDBj 1e-37 32.1 %
:RPS:PDB   1->40 3dfzB PDBj 7e-05 22.5 %
:RPS:PDB   15->436 2am1A PDBj 7e-51 13.4 %
:RPS:SCOP  7->109 1b73A1  c.78.2.1 * 9e-08 16.7 %
:RPS:SCOP  98->309 1e0dA3  c.72.2.1 * 1e-28 28.2 %
:RPS:SCOP  310->450 1e0dA2  c.59.1.1 * 7e-43 38.0 %
:HMM:SCOP  1->97 2uagA1 c.5.1.1 * 1.2e-16 39.8 %
:HMM:SCOP  98->308 2uagA3 c.72.2.1 * 3.6e-57 40.6 %
:HMM:SCOP  310->451 2uagA2 c.59.1.1 * 1.2e-42 47.8 %
:RPS:PFM   143->283 PF08245 * Mur_ligase_M 3e-15 38.2 %
:HMM:PFM   113->291 PF08245 * Mur_ligase_M 2.2e-49 46.2 173/188  
:HMM:PFM   311->381 PF02875 * Mur_ligase_C 1.3e-10 34.3 70/91  
:HMM:PFM   4->88 PF01488 * Shikimate_DH 1.3e-05 26.2 84/135  
:BLT:SWISS 1->456 MURD_DESRM 0.0 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABO49212.1 GT:GENE ABO49212.1 GT:PRODUCT UDP-N-acetylmuramoylalanine--D-glutamate ligase GT:DATABASE GIB00494CH01 GT:ORG dred0 GB:ACCESSION GIB00494CH01 GB:LOCATION 726618..727988 GB:FROM 726618 GB:TO 727988 GB:DIRECTION + GB:PRODUCT UDP-N-acetylmuramoylalanine--D-glutamate ligase GB:NOTE TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein KEGG: chy:CHY_2071 UDP-N-acetylmuramoylalanine--D-glutamate ligase GB:PROTEIN_ID ABO49212.1 GB:DB_XREF GI:134051241 InterPro:IPR004101 InterPro:IPR005762 InterPro:IPR013221 LENGTH 456 SQ:AASEQ MNFLGKRVLVVGAGLSGQAVCKFLQEKQSVVTLTDTRTREQIGQAIVQLSELGIELILGEYPSVDKGQYDMLVMSPGVPLTILPVVQAKKFDIPVLGELELAYRFAKAPIVAITGTNGKTTTTTLTGQLFRDAGFKTLVAGNIGLPMVSEIENYQVGDIVVAEVSSFQLETTEYFAPKVAVMLNLTPDHLDRHGSMEEYIKAKSCIFIHQKPSDYVVLNYDDLALRELAKSCPSQVIFFSRQHIIEKGSFIQNDKIMVSGKGGPEEVIDVNALRIPGPHNLENALAATAAAYTLGLSPRDIAGTLGRFTGVAHRLEFVANINGVEYVNDSKGTNPDAAIKALESYDAPIILIAGGKNKGISFNDFAKKIKEKVRVLITLGVHGYQIEEAAREQGFTNIYPVEDYAQAVQLARKQAKPGEIVLLSPACTSWDMFKSFEERGELFKKLVLEMQKNESF GT:EXON 1|1-456:0| SW:ID MURD_DESRM SW:DE RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; EC=6.3.2.9;AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase;AltName: Full=D-glutamic acid-adding enzyme; SW:GN Name=murD; OrderedLocusNames=Dred_0673; SW:KW ATP-binding; Cell cycle; Cell division; Cell shape;Cell wall biogenesis/degradation; Complete proteome; Cytoplasm;Ligase; Nucleotide-binding; Peptidoglycan synthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->456|MURD_DESRM|0.0|100.0|456/456| GO:SWS:NREP 9 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0007049|"GO:cell cycle"|Cell cycle| GO:SWS GO:0051301|"GO:cell division"|Cell division| GO:SWS GO:0008360|"GO:regulation of cell shape"|Cell shape| GO:SWS GO:0007047|"GO:cellular cell wall organization"|Cell wall biogenesis/degradation| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0009252|"GO:peptidoglycan biosynthetic process"|Peptidoglycan synthesis| SEG 51->60|elgielilge| SEG 114->127|tgtngktttttltg| SEG 284->294|alaataaaytl| BL:PDB:NREP 1 BL:PDB:REP 2->450|2uagA|1e-37|32.1|420/428| RP:PDB:NREP 2 RP:PDB:REP 1->40|3dfzB|7e-05|22.5|40/199| RP:PDB:REP 15->436|2am1A|7e-51|13.4|411/442| RP:PFM:NREP 1 RP:PFM:REP 143->283|PF08245|3e-15|38.2|136/187|Mur_ligase_M| HM:PFM:NREP 3 HM:PFM:REP 113->291|PF08245|2.2e-49|46.2|173/188|Mur_ligase_M| HM:PFM:REP 311->381|PF02875|1.3e-10|34.3|70/91|Mur_ligase_C| HM:PFM:REP 4->88|PF01488|1.3e-05|26.2|84/135|Shikimate_DH| GO:PFM:NREP 2 GO:PFM GO:0005524|"GO:ATP binding"|PF08245|IPR013221| GO:PFM GO:0009058|"GO:biosynthetic process"|PF08245|IPR013221| RP:SCP:NREP 3 RP:SCP:REP 7->109|1b73A1|9e-08|16.7|102/105|c.78.2.1| RP:SCP:REP 98->309|1e0dA3|1e-28|28.2|195/196|c.72.2.1| RP:SCP:REP 310->450|1e0dA2|7e-43|38.0|137/140|c.59.1.1| HM:SCP:REP 1->97|2uagA1|1.2e-16|39.8|93/93|c.5.1.1|1/1|MurCD N-terminal domain| HM:SCP:REP 98->308|2uagA3|3.6e-57|40.6|202/204|c.72.2.1|1/1|MurD-like peptide ligases, catalytic domain| HM:SCP:REP 310->451|2uagA2|1.2e-42|47.8|138/140|c.59.1.1|1/1|MurD-like peptide ligases, peptide-binding domain| OP:NHOMO 926 OP:NHOMOORG 869 OP:PATTERN -------------------------------------------------------------------- 11111111111111-1111-11111111111121111111111111111--1111111111111211121111111111111211111111111111--21111111111111111111111111111111111111--21---111111111111111111111111111111111111111111112112111111112221211121211111222114111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112331111111111112211111111311211121133213122113111111-111111111111111111111111111111111-111111111111111111111111111111111111111111111111--1111111--------11111111111111111111111111111111111111111111111111111111111111111111111111111112111111111121111121111111112222211211111111111111-111111111111111111111111111111111111111111111111111111111-1111111-11111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111--------------------------1111111111111 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---1------2--1--3--1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 450 STR:RPRED 98.7 SQ:SECSTR cccTTccEEEEcccccHHHHHHHHTcccccTTccccccccTEEccGGGccTTcEEcccccccHTcGGGGHHHHHHHTccEEEEccccccccEEEcccHHHHHHHHHccEEEEEEcccccccHHHHHHHHTTTccEEEccTTcccTTHHHHHHHTcTTcEEEEEccccTTHHHHHHcccEEEEccccccccTTcccHHHHHHHHGGGTTGGTcTTcEEEEEccGGGGGGcccccEEEEEcTTccccEEEEEEccccEEEEETTcccEEEEGGEEccccHHHHHHHHHHHHHHHHTTccHHHHHHHGGGcccccccccEEccTTTcEEEEEcccccHHHHHTTcccccccEEEEEEcTTHHHHHHHGGGccTTTccEEEEEEcTTHHHHcTTcEEEEEccccccTHHHHHHHHHHHccTTEEEEEEccccHHHHHHHHHHHHHHHHHHHHHH###### DISOP:02AL 1-1,452-457| PSIPRED ccccccEEEEEEEcHHHHHHHHHHHHcccEEEEEEcccccccHHHHHHHHHcccEEEEccccHHHcccccEEEEccccccccHHHHHHHHcccHHHHHHHHHHHHccccEEEEEcccccHHHHHHHHHHHHHccccEEEEcccHHHHHHHHHccccccEEEEEccccHHHHHcccccEEEEEccccHHHHHHcccHHHHHHHHHHHHHHcccccEEEEccccHHHHHHHHHccccEEEEccccccccccEEEccEEEEEEEccccEEEcHHHcccccHHHHHHHHHHHHHHHHccccHHHHHHHHHHcccccccEEEEEccccEEEEEEcccccHHHHHHHHHHccccEEEEEccccccccHHHHHHHHHHcccEEEEEcccHHHHHHHHHHcccccEEEEccHHHHHHHHHHHcccccEEEEEccHHHHHHHHHHHHHHHHHHHHHHHHHHcccc //