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Desulfotomaculum reducens MI-1 (dred0)
Gene : ABO49946.1
DDBJ      :             DNA helicase/exodeoxyribonuclease V, subunit A
Swiss-Prot:ADDA_DESRM   RecName: Full=ATP-dependent helicase/nuclease subunit A;         EC=3.6.1.-;AltName: Full=ATP-dependent helicase/nuclease addA;

Homologs  Archaea  8/68 : Bacteria  419/915 : Eukaryota  5/199 : Viruses  0/175   --->[See Alignment]
c.37.1c.52.1
:1244 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   344->827 3pjrA PDBj 1e-19 29.2 %
:RPS:PDB   465->739 3bm3A PDBj 5e-17 10.0 %
:RPS:PDB   718->905 3dmnA PDBj 1e-09 14.8 %
:RPS:SCOP  47->143,591->913 1qhh.1  c.37.1.19 * 4e-26 24.9 %
:RPS:SCOP  396->500 1pjrA1  c.37.1.19 * 2e-07 31.0 %
:RPS:SCOP  1031->1244 1w36B3  c.52.1.24 * 3e-19 16.0 %
:HMM:SCOP  4->904 1qhh.1 c.37.1.19 * 3e-107 32.7 %
:HMM:SCOP  1030->1236 1w36B3 c.52.1.24 * 1.1e-35 29.2 %
:RPS:PFM   50->152,302->682 PF00580 * UvrD-helicase 1e-32 38.6 %
:HMM:PFM   6->741 PF00580 * UvrD-helicase 5.7e-121 34.4 520/533  
:BLT:SWISS 1->1244 ADDA_DESRM 0.0 100.0 %
:COIL
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABO49946.1 GT:GENE ABO49946.1 GT:PRODUCT DNA helicase/exodeoxyribonuclease V, subunit A GT:DATABASE GIB00494CH01 GT:ORG dred0 GB:ACCESSION GIB00494CH01 GB:LOCATION 1533786..1537520 GB:FROM 1533786 GB:TO 1537520 GB:DIRECTION + GB:PRODUCT DNA helicase/exodeoxyribonuclease V, subunit A GB:NOTE TIGRFAM: UvrD-like DNA helicase, C terminal PFAM: UvrD/REP helicase KEGG: cno:NT01CX_1236 ATP-dependent nuclease subunit A GB:PROTEIN_ID ABO49946.1 GB:DB_XREF GI:134051975 InterPro:IPR000212 InterPro:IPR014016 InterPro:IPR014017 LENGTH 1244 SQ:AASEQ MSDKKWTAEQLAAITTRDTNLLVAAAAGAGKTAVLVERIIGLITDPHRPVDVDQLLIVTFTNAAAAEMRERIGQALSKALQENPHSKRLARQLTMLNRASITTLHSFCLDLLRRYFYQLDLDPGFRVADEVEAELLRLDVLEELFERRYNQDNVEVFARLVDSYGGQRDDSRLQDLVLELYRFSGSHPLPVQWLTSLAENYVIPEGKTLDDQTWIVQIKKTIFQEVEGVLGLLKQAQWLAKQPGGPEPYSKTLTEDIINIKPLTNNDWDASWEKLYRSITAIKWSKLSPCRGEIDDQLKNKAQNLRNKAKEKFNDIINTYFSAEPTVILEDLRSLQPLIADLAKLTIEFMELYQKKKQAKGLVDFGDLEHYCLTILLDKENDAAEFRPSAVAIELQQQYAEVLVDEYQDINAVQETILRLVSKKNNRFMVGDVKQSIYRFRLAEPKLFLSKSELYANTDNCQGTRIGLSKNFRSRLEVVNAVNFIFRQIMTKKAGEITYDELEELHCGADYPQAEDVKTATGPVEVYLIDRKDAQLEEQNTDSAEEKLTDGEEQEDLDSDQAEARLIGRRIQAMVKGTDKAMGPEFKVWDKEIGKYRPVSYRDIVILLRATTGRANTFLEELRTMGVPTYAEVGTGYFEAVEVETFLSLLKIIDNPRQDVPLAGVLRSPVVGLKASDLAEIRLCSKEGDFYDAVRIAAAADLGDVAVTLTKFLRQLENWRSRARRDTLADLIWLLYRETGYYDYVGGMVGGTQRQANLRVLYHRAKQFEATSFRGLFRFLRFVERLKDSGSDLGAARSLSENEDVVRIMSIHKSKGLEFPVLFVAGLGKRFNMMDLNKDMLMHKELGLGPQIIHLGSRVSYPSLPKLLIKQQIRKESVAEEMRVLYVALTRAREKLILVGAVRDLEKSLEKWCTSTYQAGWTLPDAELMAAKCYLDWLCPAIARHHNGHELRSLAKTEGQPFSEVATDPSAWQLVFQALKDIKNQTQENKEQSQGLLVKIKDMEPFEDAGLIKEVERRLSWQYPRAEVTTRPAKAAVTEVKHKFDELARQEAGVMSYRPKISGRPRFLQQDKGLTPAERGSAIHLVMQHIPLDKLPDEEGVQVLLQNLIQKEILLPQQAAAINPNHITGFFASSIGQRVLQAPKVERELPFSLALPATEVYQELPECGDEMVLVQGVIDCLVDEGDGFLLIDYKSDAVYPGQDSPVDRYRGQINLYARAVQDILGKPVKDRVIYLFNNGQIVHI GT:EXON 1|1-1244:0| SW:ID ADDA_DESRM SW:DE RecName: Full=ATP-dependent helicase/nuclease subunit A; EC=3.6.1.-;AltName: Full=ATP-dependent helicase/nuclease addA; SW:GN Name=addA; OrderedLocusNames=Dred_1416; SW:KW ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding;Exonuclease; Helicase; Hydrolase; Nuclease; Nucleotide-binding. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->1244|ADDA_DESRM|0.0|100.0|1244/1244| GO:SWS:NREP 9 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0006974|"GO:response to DNA damage stimulus"|DNA damage| GO:SWS GO:0006281|"GO:DNA repair"|DNA repair| GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0004527|"GO:exonuclease activity"|Exonuclease| GO:SWS GO:0004386|"GO:helicase activity"|Helicase| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0004518|"GO:nuclease activity"|Nuclease| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| COIL:NAA 27 COIL:NSEG 1 COIL:REGION 977->1003| SEG 21->36|llvaaaagagktavlv| SEG 740->751|gyydyvggmvgg| BL:PDB:NREP 1 BL:PDB:REP 344->827|3pjrA|1e-19|29.2|397/646| RP:PDB:NREP 2 RP:PDB:REP 465->739|3bm3A|5e-17|10.0|221/257| RP:PDB:REP 718->905|3dmnA|1e-09|14.8|142/159| RP:PFM:NREP 1 RP:PFM:REP 50->152,302->682|PF00580|1e-32|38.6|380/449|UvrD-helicase| HM:PFM:NREP 1 HM:PFM:REP 6->741|PF00580|5.7e-121|34.4|520/533|UvrD-helicase| GO:PFM:NREP 4 GO:PFM GO:0003677|"GO:DNA binding"|PF00580|IPR000212| GO:PFM GO:0004003|"GO:ATP-dependent DNA helicase activity"|PF00580|IPR000212| GO:PFM GO:0005524|"GO:ATP binding"|PF00580|IPR000212| GO:PFM GO:0006281|"GO:DNA repair"|PF00580|IPR000212| RP:SCP:NREP 3 RP:SCP:REP 47->143,591->913|1qhh.1|4e-26|24.9|346/623|c.37.1.19| RP:SCP:REP 396->500|1pjrA1|2e-07|31.0|100/315|c.37.1.19| RP:SCP:REP 1031->1244|1w36B3|3e-19|16.0|213/276|c.52.1.24| HM:SCP:REP 4->904|1qhh.1|3e-107|32.7|578/0|c.37.1.19|1/1|P-loop containing nucleoside triphosphate hydrolases| HM:SCP:REP 1030->1236|1w36B3|1.1e-35|29.2|202/0|c.52.1.24|1/1|Restriction endonuclease-like| OP:NHOMO 586 OP:NHOMOORG 432 OP:PATTERN --------------------------1-------2-----11--1111-------------------- --2---11111-----------------------------1---2-21---1-----1--------1--1-----1--12-11--1--111--1---------1-1--11--------------1--1--11--11--------1--11111111--111---2-------1--1-----11------22122233333333133334331221233222212111111112311111111111111121111121211211112211112112111111111111111111111111111111111111111111111111113232222222222232223222333113332121-11112111111-1--1-2111111-1-11--2112121111111111111-----3-1-1-1-111--3111211-3222111-1--11----------11-----1121211111111111-111-111-2122121121----1-------------1----------111111111------11---11-11--1----1----21---3112-1--1------2-2111113--------11-1-11------1122-31----122-------1----------------------------1---------------------------------------------------1----------------------------------------111111---------------1-------------------122121-----1---------------11-1------11---11--------------1-222222---1-11122----------1-1-111-----1---1--221-1-1--- --------------------------------------------------1----------------------------------------------------1-1--1----------------------------------------------------------------------------1------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 679 STR:RPRED 54.6 SQ:SECSTR ####################################HHHHHHHH##HHHcccHHHHHHHHHHHHHHTccEEEcccccccccccHHHHHHHHHcHccccccEEEcHHHHHHHHHHHHHHHHHHHccccccHHH####HHHHHHHHTcTTccccHH#HHHHHHHHHHHHHTT######################################################################################################################################################cTHHHHHTTccc#ccHHHH##HHHHHHHHHHHHHHHHHHHHHTccEEEHHHHTTEETTEEcccccHH###HHHHccccccEEEEccGGGccHHHHHHHTTccTTcEEEEEEcTTcccccccHHHHccEEEcccccHHHHTcTcccccccTTccGGGGcccHHHHHHHHHHHHTHHHHHHTTTcccTTccTTcccccTTcccccccHHGGGTccHHHHTcccccccccHHHHEETTHHHHHHHHHHHHHHHHHHHHHHcEEEEEcHHHHTTccHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTccccccccEEccTTcccEEcccEEHHHHEccHHHHHHcGGGcEEEEEEcccTTTHHHHHHHHHHHHHcTTccEEEEccTTccHHHHHHHHTTccEEEEcHHHHHHHHTcccTTEEEEEEEEEEEccEEEccHHHHHHHHTTccTTcEEEEcTTcHHHHHHHTTcEEEEccccEEEEccccGGGccccccccccccccEETccTTTc########TTT#cTTTTT##################EEEEcHHHHHHHHHHHHHTTccEEEEEEETTEEEEEE################################################################################################################################################################################################################################################################################################################################################### DISOP:02AL 1-4,791-802,907-917,981-993| PSIPRED cccccccHHHHHHHHcccccEEEEEcccccHHHHHHHHHHHHHHcccccccHHHEEEEEEcHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHcccccEEEEHHHHHHHHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHccccHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHccHHHcccccHHccHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHcccccccccccHHHHHHHHccccEEEEccHHHccHHHHHHHHHHcccccEEEEEcccHHHHHHccccHHHHHHHHHHcccccccccEEEEEccccccHHHHHHHHHHHHHHccccccccccccccHHHcccccccccHHHHcccccEEEEccccccccccccccccccccccccccccccccHHHHHHHHHHHHHHHHHccccccccHHHHHHHHHcccccccHHHEEEEEEccccHHHHHHHHHHHccccEEEEccccHHHHHHHHHHHHHHHHHHcccccHHHHHHHccccccccHHHHHHHHHHHccccHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHccHHHHHHccccHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHcccccHHHHccccccccEEEEEEccccccccccEEEEEcccccccccccccccccccccccccccccccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEcccccccccccccHHHHHHccccHHHHHHHccHHHHHHHHHHHHHHHHHHHHcccccccccccccccccccEEEccccccccHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHcccHHHccccccccHHHHHHHccccccHHHHHHHHccccccccccccccccccccHHHHHHHHHHHHccccccccHHHHHHHHHHHHHcccccHHHHHcccHHHHHHHHccHHHHHHcccHHccHHHHHHHcccHHHHHcccccccccEEEEEEEEEEEEEEccEEEEEEcccccccccHHHHHHHHHHHHHHHHHHHHHHHcccccEEEEEEEccccEEEc //