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Desulfotomaculum reducens MI-1 (dred0)
Gene : ABO50084.1
DDBJ      :             GAF sensor hybrid histidine kinase
Swiss-Prot:             

Homologs  Archaea  30/68 : Bacteria  853/915 : Eukaryota  117/199 : Viruses  1/175   --->[See Alignment]
a.154.1a.26.1a.274.1a.30.2c.23.1d.110.2d.110.3d.122.1
:1021 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   608->825 3dgeA PDBj 2e-32 36.3 %
:BLT:PDB   854->971 1mvoA PDBj 2e-15 38.3 %
:RPS:PDB   201->246 2aswA PDBj 2e-04 30.4 %
:RPS:PDB   308->455 3eeaA PDBj 2e-11 15.5 %
:RPS:PDB   469->531 2btvA PDBj 1e-04 11.1 %
:RPS:PDB   502->614 1dp8A PDBj 9e-08 9.7 %
:RPS:PDB   605->748 3ckeD PDBj 2e-17 9.7 %
:RPS:PDB   735->933 2dvyF PDBj 8e-41 12.1 %
:RPS:PDB   940->971 1d2iB PDBj 6e-04 9.4 %
:RPS:SCOP  203->251 2aswA1  a.274.1.1 * 5e-05 26.5 %
:RPS:SCOP  232->293 1l8wA  a.154.1.1 * 2e-07 9.7 %
:RPS:SCOP  301->480 1mc0A1  d.110.2.1 * 1e-12 14.7 %
:RPS:SCOP  481->603 3c2wA3  d.110.3.9 * 3e-07 14.3 %
:RPS:SCOP  585->673 1csgA  a.26.1.2 * 7e-11 9.1 %
:RPS:SCOP  673->840 1bxdA  d.122.1.3 * 9e-29 19.6 %
:RPS:SCOP  855->971 1a0oA  c.23.1.1 * 4e-22 24.1 %
:HMM:SCOP  294->480 1mc0A1 d.110.2.1 * 9.6e-22 20.7 %
:HMM:SCOP  465->603 1ew0A_ d.110.3.2 * 3.8e-08 27.4 %
:HMM:SCOP  593->679 2c2aA1 a.30.2.1 * 3.2e-20 43.7 %
:HMM:SCOP  666->830 1jm6A2 d.122.1.4 * 1.1e-44 42.7 %
:HMM:SCOP  854->971 1s8nA_ c.23.1.1 * 9.3e-28 36.8 %
:RPS:PFM   198->246 PF00672 * HAMP 8e-06 38.8 %
:RPS:PFM   313->449 PF01590 * GAF 4e-04 30.4 %
:RPS:PFM   435->504 PF04888 * SseC 3e-04 30.0 %
:RPS:PFM   614->675 PF00512 * HisKA 1e-05 37.1 %
:RPS:PFM   724->831 PF02518 * HATPase_c 5e-25 45.4 %
:RPS:PFM   856->966 PF00072 * Response_reg 6e-14 38.0 %
:HMM:PFM   721->830 PF02518 * HATPase_c 1.8e-33 39.4 109/111  
:HMM:PFM   611->676 PF00512 * HisKA 1.9e-24 47.0 66/68  
:HMM:PFM   856->965 PF00072 * Response_reg 1.5e-21 37.4 107/112  
:HMM:PFM   184->248 PF00672 * HAMP 8.9e-14 32.8 64/70  
:HMM:PFM   494->602 PF00989 * PAS 6.9e-06 28.0 107/113  
:HMM:PFM   314->448 PF01590 * GAF 0.00034 25.2 135/154  
:HMM:PFM   261->311 PF04156 * IncA 0.00045 25.5 51/191  
:BLT:SWISS 198->323 TLPA_BACSU 5e-06 23.8 %
:BLT:SWISS 441->528 SYNE2_HUMAN 2e-04 31.2 %
:BLT:SWISS 584->998 ARCB_SHIFL 4e-43 32.1 %
:TM
:COIL
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABO50084.1 GT:GENE ABO50084.1 GT:PRODUCT GAF sensor hybrid histidine kinase GT:DATABASE GIB00494CH01 GT:ORG dred0 GB:ACCESSION GIB00494CH01 GB:LOCATION 1690466..1693531 GB:FROM 1690466 GB:TO 1693531 GB:DIRECTION + GB:PRODUCT GAF sensor hybrid histidine kinase GB:NOTE TIGRFAM: PAS sensor protein PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein KEGG: sth:STH843 two-component sensor histidine kinase GB:PROTEIN_ID ABO50084.1 GB:DB_XREF GI:134052113 InterPro:IPR000014 InterPro:IPR001789 InterPro:IPR003594 InterPro:IPR003660 InterPro:IPR003661 InterPro:IPR004358 InterPro:IPR005467 LENGTH 1021 SQ:AASEQ MNMGKKLFASYMVFVLIIGIIVSTDYYDSKMTKKHTVEIAELKPLNDVIQNLSYDFLMQRNSINQYIVSKDLAALDTYREYHLKAEKDITHLKDFTNKFPEISTEIEAAIMESRQQNKALNEIVNQAVFEGVQDSKILFSNSRHQDDEFLFALNNLQNKTQNIIRNSLNKMVQQSEDLHQFNYLLLILSLPLGVILGYVLSKRYTNPIRKLIKATAKDENGNYKTIHGVLPKDEVGILATAFNDMVITINNEHSLLKEQNLKLLSQQEEMSAQNEEIRAQQEELSAILDQVNAEQDKLLQLHEFNTLLNESIELTVLSDTILRYCLKAFKADAGALLVKDPDEEAIYIAASAGLDASVGETIPMDNLRGLVKRCYLEQQSIIVSYPATEVSAGIRLAETQRSAHEVYVPFTFNSQKLGFIILSKLSGNRFHDNEVTLLEAQMSQGAMAINNALVYKRIEKMYEDILEQAALVEQLNAQLETEKDNLSRAREITRSVVESINEAIVMVNIDDEVVAVNKRWQELFEYEGDLRGSSSEVLFRTSIDCLENSAEAYNKLTEIMAHPMNQGEFNAVQENRVLRVWTGPVLDRAENLIGRLYVFRDITIEAEVDRMKSEFVSTVSHELRTPLSSILGFSELLLIKKLSEEARTKYTKTIHKEAKRLTDLVNDFLDLQRMELGKQVYDKEDFIALDLLAEVVESFAASGVDHDITLQTVERFFINADKERVTQVLINLLSNAVKFSPKGTKITLGVTPDEEYAKFFIKDQGLGIPKDVQDNLFSKFYRVDNSDRRKIGGTGLGLSICKEIVEAHGGKIWVESEHGHGSVFYFTVKLSEKSITGDAEINSAPRLQKDKSIKRVLLVEDDRSLALLFKEHLADCGYRVEVRATGEEALKTIKHSKPDVIILDILLAGEMNGWTILQTLKQDKSTENIPIIVSSCLPEKEQALALGANEYLIKPFEPQLLIRIVKDLLSREKDSQTFMIVPKNQKVSQLLVMRLKEKGFFVKDIIDEKEAILVSMDKPID GT:EXON 1|1-1021:0| BL:SWS:NREP 3 BL:SWS:REP 198->323|TLPA_BACSU|5e-06|23.8|126/662| BL:SWS:REP 441->528|SYNE2_HUMAN|2e-04|31.2|77/6885| BL:SWS:REP 584->998|ARCB_SHIFL|4e-43|32.1|408/778| COIL:NAA 83 COIL:NSEG 2 COIL:REGION 255->303| COIL:REGION 459->492| TM:NTM 2 TM:REGION 7->26| TM:REGION 180->201| SEG 184->197|lllilslplgvilg| SEG 634->645|selllikklsee| BL:PDB:NREP 2 BL:PDB:REP 608->825|3dgeA|2e-32|36.3|215/237| BL:PDB:REP 854->971|1mvoA|2e-15|38.3|115/121| RP:PDB:NREP 7 RP:PDB:REP 201->246|2aswA|2e-04|30.4|46/56| RP:PDB:REP 308->455|3eeaA|2e-11|15.5|148/153| RP:PDB:REP 469->531|2btvA|1e-04|11.1|63/845| RP:PDB:REP 502->614|1dp8A|9e-08|9.7|113/118| RP:PDB:REP 605->748|3ckeD|2e-17|9.7|144/284| RP:PDB:REP 735->933|2dvyF|8e-41|12.1|199/211| RP:PDB:REP 940->971|1d2iB|6e-04|9.4|32/213| RP:PFM:NREP 6 RP:PFM:REP 198->246|PF00672|8e-06|38.8|49/69|HAMP| RP:PFM:REP 313->449|PF01590|4e-04|30.4|135/143|GAF| RP:PFM:REP 435->504|PF04888|3e-04|30.0|70/300|SseC| RP:PFM:REP 614->675|PF00512|1e-05|37.1|62/69|HisKA| RP:PFM:REP 724->831|PF02518|5e-25|45.4|108/112|HATPase_c| RP:PFM:REP 856->966|PF00072|6e-14|38.0|108/111|Response_reg| HM:PFM:NREP 7 HM:PFM:REP 721->830|PF02518|1.8e-33|39.4|109/111|HATPase_c| HM:PFM:REP 611->676|PF00512|1.9e-24|47.0|66/68|HisKA| HM:PFM:REP 856->965|PF00072|1.5e-21|37.4|107/112|Response_reg| HM:PFM:REP 184->248|PF00672|8.9e-14|32.8|64/70|HAMP| HM:PFM:REP 494->602|PF00989|6.9e-06|28.0|107/113|PAS| HM:PFM:REP 314->448|PF01590|0.00034|25.2|135/154|GAF| HM:PFM:REP 261->311|PF04156|0.00045|25.5|51/191|IncA| GO:PFM:NREP 11 GO:PFM GO:0004871|"GO:signal transducer activity"|PF00672|IPR003660| GO:PFM GO:0007165|"GO:signal transduction"|PF00672|IPR003660| GO:PFM GO:0016021|"GO:integral to membrane"|PF00672|IPR003660| GO:PFM GO:0009405|"GO:pathogenesis"|PF04888|IPR006972| GO:PFM GO:0000155|"GO:two-component sensor activity"|PF00512|IPR003661| GO:PFM GO:0007165|"GO:signal transduction"|PF00512|IPR003661| GO:PFM GO:0016020|"GO:membrane"|PF00512|IPR003661| GO:PFM GO:0005524|"GO:ATP binding"|PF02518|IPR003594| GO:PFM GO:0000156|"GO:two-component response regulator activity"|PF00072|IPR001789| GO:PFM GO:0000160|"GO:two-component signal transduction system (phosphorelay)"|PF00072|IPR001789| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF00072|IPR001789| RP:SCP:NREP 7 RP:SCP:REP 203->251|2aswA1|5e-05|26.5|49/54|a.274.1.1| RP:SCP:REP 232->293|1l8wA|2e-07|9.7|62/271|a.154.1.1| RP:SCP:REP 301->480|1mc0A1|1e-12|14.7|177/187|d.110.2.1| RP:SCP:REP 481->603|3c2wA3|3e-07|14.3|112/113|d.110.3.9| RP:SCP:REP 585->673|1csgA|7e-11|9.1|88/120|a.26.1.2| RP:SCP:REP 673->840|1bxdA|9e-29|19.6|158/161|d.122.1.3| RP:SCP:REP 855->971|1a0oA|4e-22|24.1|116/128|c.23.1.1| HM:SCP:REP 294->480|1mc0A1|9.6e-22|20.7|184/0|d.110.2.1|1/1|GAF domain-like| HM:SCP:REP 465->603|1ew0A_|3.8e-08|27.4|117/130|d.110.3.2|1/1|PYP-like sensor domain (PAS domain)| HM:SCP:REP 593->679|2c2aA1|3.2e-20|43.7|87/0|a.30.2.1|1/1|Homodimeric domain of signal transducing histidine kinase| HM:SCP:REP 666->830|1jm6A2|1.1e-44|42.7|164/190|d.122.1.4|1/1|ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase| HM:SCP:REP 854->971|1s8nA_|9.3e-28|36.8|114/190|c.23.1.1|1/1|CheY-like| OP:NHOMO 18202 OP:NHOMOORG 1001 OP:PATTERN -----------------------4M5454G6D--42-1232257D-9P7SH5C-1-11---------7 Fn*4H3667775555AA99-9C44CB888889FCDC59GB9CEF7783677499A46811CET4K5DLKJ7455555574KBB238ABlk*h-r223--G7gCQH*Zxaq-------1--11113984CA58GDTA**ysmOCF*5*r**mlLOPIJ567999bjNe***T785876796866VKC55687GHJiijikgkkTniqqocPRKJIIlpvGLPZDMJECCDCE**CAA9A99999AAA99A78A8D7B7AB866488877BA778997575FGF98796667677776777756666666676667556645559AkRW*VVUaadZcXWJgffGIMHVTU88HLOL9nlhTND7CC9FCG844BZQWmggR98898LMicfKFGXUXTWEEEDDDDDEEI-bThUXceqIPU6PPPWQQNWdVQQLMJKSGCHJILJDREFFFFFFFFB87AA*aS44544223445A233323442322443444BHH89AB86IfcehmfVJIJHhgqoPPPPDOkhqSYWe16SYPmPSEEaabXV5IRXGMHGVA221121399JOg*Y**YMJrOC*qTRd4*******Onqj*q**LrA4455333322-1-------GD56H88QLCeOdf8eVKQJNONMONPKKMSMLROUZ--4ECIJ------IGDDHGBKKKLKMKNIK-KNLJJJJIJLKKKIJKJJHPOPDFDDAGGFGGIGGFHHGHGGIIHGDHGHK8-JHIJKJIGGJKJ--4D787778988ALzBc333333121123124IHEHJBG6A9SQgghgdxtsYmpulgkmn322214312FMPNXMNNNNUWRabUVWTXTTLOO8655--*4XXIMQQ211111123-1-------------------------6G867AAA8A8*5 --1-CD1------1KAAFB678696864433333334444344444BB88776B57644787331111-2-1221------2222223-262A352343375388D-71N------------------------------------------------6----4---------4--565R13134k47JEAJ71F2432 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------4- STR:NPRED 812 STR:RPRED 79.5 SQ:SECSTR ########################################################################################################################################################################################################HHHHHHHHHHHHHHHHHHHTTcTTccTTTTcccHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccHHHHHHHGGGGccHHHHHHHHHHHHHHHccccEEEEEEEccccEEEEEEEcccGGGHHHHccccTTTcHHHHHHHHHTccEEEccGGGcTTccHHHHHHTTTEEEEEEEEEETTEEEEEEEEEETTcccccHHHHHHHHHHHHHHHHHHHHHHTccccc#########HGGHHHHHHHHTTcccHHHHHHHHHHHHHHHHHHHHHHHTTccHHHccTTHHHHHHHHTccccccHHHHHHHHTTcccccHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHTccHHHHTcHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHTTTHHHHHHHHHHHHHHHTcccHHHHHHHHHHHHHHHHHHHHHHHHHcccTTcEEEEEHHHHHHHHHHHHHHHHHHHHcccccEEEEEEEccccEEEEcHHHHHHHHHHHHHcEEEccTTccEEEEccccccccEEEEEEccccEEEccTTccccccGGGTTcEEEEcccccccHHHHHHHHHHHTccccTTHHHHHHHHHTTccccHHccEEEccccEETTEEccEEEcccEEcccTTccEEEEEEcccccEEEEEEccGGGEEcccccccccTTccEEEEccHHHHHHHHHTTcHHHHHHHHHHHHHccHHHHHHHHHHHHTTcccHHHHHHHHHHHHHHHTccEEEEHEETTccccTTHHHHHHHHHHHHHHHEcEEEEEETTEEcccEEHHHHHH DISOP:02AL 1-4,113-113,214-228,643-644,786-788,841-845,970-980,1020-1022| PSIPRED cccHHHHHHHHHHHHHHHHHHHHEEEcccccccEEEEEEHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHccccHHHHHHHcccHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccEEEEEEEEccccEEEEEEEccccHHHHHHHHHHccccHHHHHHHcccEEEEEccccccccccccccccccHHEEEEEEEEccEEEEEEEEEccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccEEEEEEccccEEEEcHHHHHHHcccHHHccccHHHHHcccHHHHHHHHHHHHHHHHHHcccccEEEEEEEcccEEEEEEEEEEEcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccEEEEEEEccHHHHHHHHHHHHHHHHHHcccEEEcccccEEEEcHHHHHHHHHHHHcccEEEcccccEEEEEEEEEccEEEEEEEEccccccHHHHHHHHHHHHHccccccccccccccHHHHHHHHHHHcccEEEEEEEccccEEEEEEEEcccccccccccccccccccccccccEEEEEcccHHHHHHHHHHHHHcccEEEEEccHHHHHHHHHcccccEEEEEccccccccHHHHHHHHHHcccccccEEEEEcccHHHHHHHHccccEEEEccccHHHHHHHHHHHHccccccccEEEEcccHHHHHHHHHHHHHcccEEEEEccHHHHHHHHHHcccc //