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Desulfotomaculum reducens MI-1 (dred0)
Gene : ABO50321.1
DDBJ      :             D-alanine--D-alanine ligase
Swiss-Prot:DDL_DESRM    RecName: Full=D-alanine--D-alanine ligase;         EC=6.3.2.4;AltName: Full=D-alanylalanine synthetase;AltName: Full=D-Ala-D-Ala ligase;

Homologs  Archaea  5/68 : Bacteria  869/915 : Eukaryota  18/199 : Viruses  0/175   --->[See Alignment]
c.30.1d.142.1
:312 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->309 1iovA PDBj 2e-63 42.1 %
:RPS:PDB   4->312 1ehiA PDBj 8e-39 32.1 %
:RPS:SCOP  3->95 1ehiA1  c.30.1.2 * 9e-28 33.3 %
:RPS:SCOP  97->311 1e4eA2  d.142.1.1 * 8e-50 37.6 %
:HMM:SCOP  1->97 1iowA1 c.30.1.2 * 2e-30 58.3 %
:HMM:SCOP  98->306 1iowA2 d.142.1.1 * 1.2e-50 40.0 %
:RPS:PFM   3->87 PF01820 * Dala_Dala_lig_N 2e-17 60.7 %
:RPS:PFM   104->307 PF07478 * Dala_Dala_lig_C 8e-51 49.5 %
:HMM:PFM   105->307 PF07478 * Dala_Dala_lig_C 7.6e-62 40.7 199/203  
:HMM:PFM   4->43 PF01820 * Dala_Dala_lig_N 8.4e-13 51.3 39/117  
:HMM:PFM   53->87 PF01820 * Dala_Dala_lig_N 3e-16 65.7 35/117  
:BLT:SWISS 1->312 DDL_DESRM e-175 100.0 %
:PROS 64->75|PS00843|DALA_DALA_LIGASE_1
:PROS 253->280|PS00844|DALA_DALA_LIGASE_2

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABO50321.1 GT:GENE ABO50321.1 GT:PRODUCT D-alanine--D-alanine ligase GT:DATABASE GIB00494CH01 GT:ORG dred0 GB:ACCESSION GIB00494CH01 GB:LOCATION 1968987..1969925 GB:FROM 1968987 GB:TO 1969925 GB:DIRECTION + GB:PRODUCT D-alanine--D-alanine ligase GB:NOTE KEGG: chy:CHY_1346 D-alanine--D-alanine ligase TIGRFAM: D-alanine--D-alanine ligase PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; D-alanine--D-alanine ligase domain protein GB:PROTEIN_ID ABO50321.1 GB:DB_XREF GI:134052350 InterPro:IPR000115 InterPro:IPR000291 InterPro:IPR003135 InterPro:IPR003806 InterPro:IPR005905 InterPro:IPR011095 InterPro:IPR011127 InterPro:IPR011761 LENGTH 312 SQ:AASEQ MALRIGVLCGGRSAEREVSLRSGEAVYQALMAAGYNDVVKIDVGYDLVEQLKGNEIQVAFLALHGKYGEDGTIQGLLEMLDIPYTGSGVLASALAINKIATKKIFKMEGIPTPAFSVITKKEVEDKSLQEAALRAIKEVGVPAVVKANTQGSTIGITFVHVKEKMAEAIESALKYDQDVLVEQFVAGTEVTASVLGNNSPEALPLIEITSVTGVYDYQSKYTPGMSDHIIPPRLPQDIQEKIKELAIKSFLSLGCRGLGRIDFIIRDNQPYALEVNTLPGMTATSLFPDAANYAGISFPELTDRLIKLALEQ GT:EXON 1|1-312:0| SW:ID DDL_DESRM SW:DE RecName: Full=D-alanine--D-alanine ligase; EC=6.3.2.4;AltName: Full=D-alanylalanine synthetase;AltName: Full=D-Ala-D-Ala ligase; SW:GN Name=ddl; OrderedLocusNames=Dred_1796; SW:KW ATP-binding; Cell shape; Cell wall biogenesis/degradation;Complete proteome; Cytoplasm; Ligase; Magnesium; Manganese;Metal-binding; Nucleotide-binding; Peptidoglycan synthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->312|DDL_DESRM|e-175|100.0|312/312| GO:SWS:NREP 8 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0008360|"GO:regulation of cell shape"|Cell shape| GO:SWS GO:0007047|"GO:cellular cell wall organization"|Cell wall biogenesis/degradation| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0009252|"GO:peptidoglycan biosynthetic process"|Peptidoglycan synthesis| PROS 64->75|PS00843|DALA_DALA_LIGASE_1|PDOC00659| PROS 253->280|PS00844|DALA_DALA_LIGASE_2|PDOC00659| BL:PDB:NREP 1 BL:PDB:REP 1->309|1iovA|2e-63|42.1|304/306| RP:PDB:NREP 1 RP:PDB:REP 4->312|1ehiA|8e-39|32.1|305/360| RP:PFM:NREP 2 RP:PFM:REP 3->87|PF01820|2e-17|60.7|84/108|Dala_Dala_lig_N| RP:PFM:REP 104->307|PF07478|8e-51|49.5|198/199|Dala_Dala_lig_C| HM:PFM:NREP 3 HM:PFM:REP 105->307|PF07478|7.6e-62|40.7|199/203|Dala_Dala_lig_C| HM:PFM:REP 4->43|PF01820|8.4e-13|51.3|39/117|Dala_Dala_lig_N| HM:PFM:REP 53->87|PF01820|3e-16|65.7|35/117|Dala_Dala_lig_N| GO:PFM:NREP 5 GO:PFM GO:0005618|"GO:cell wall"|PF01820|IPR011127| GO:PFM GO:0008716|"GO:D-alanine-D-alanine ligase activity"|PF01820|IPR011127| GO:PFM GO:0009252|"GO:peptidoglycan biosynthetic process"|PF01820|IPR011127| GO:PFM GO:0008716|"GO:D-alanine-D-alanine ligase activity"|PF07478|IPR011095| GO:PFM GO:0009252|"GO:peptidoglycan biosynthetic process"|PF07478|IPR011095| RP:SCP:NREP 2 RP:SCP:REP 3->95|1ehiA1|9e-28|33.3|93/132|c.30.1.2| RP:SCP:REP 97->311|1e4eA2|8e-50|37.6|205/211|d.142.1.1| HM:SCP:REP 1->97|1iowA1|2e-30|58.3|96/0|c.30.1.2|1/1|PreATP-grasp domain| HM:SCP:REP 98->306|1iowA2|1.2e-50|40.0|205/0|d.142.1.1|1/1|Glutathione synthetase ATP-binding domain-like| OP:NHOMO 1157 OP:NHOMOORG 892 OP:PATTERN --------------------------------1-------------1---1-1--------------1 1211311111131111111-11111111111111111111221312112331111111112232222121211111112221221212111111112--111111111211111111111111111111111112111111111111111111111111111111111113111111111111111111111111132322212222221111112222112111111111331111111111111111111121111121222111111112111111111111111111111121111222222222222211111111121421111111111121211122132111112112211111111222111111-211122222115221111111133333333331-111111111211211123222211111111131111111111111111111111111--------111111111111111111111111111111111111111111112111111211111111111111111111111111111211111111111111112211221111111111111121222244221111111111111111111111111111111111111212111111111111111111-1211111----22112212222222222-2222222222222122222222111112221222222222212222222221121111111111111111111111111121111111111111111111111111111122221212121331222111-111111111211111111112212222222111111112211221111111111--------------------------1212213112121 ------2-----111-------------------------------------------1111-----------------------------------------------------------------------------------------------------1---------1----1------3112-31------1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 312 STR:RPRED 100.0 SQ:SECSTR ccEEEEEEEEcccTTHHHHHHHHHHHHHHHHHHccEEEETcccTTcTTcTTTTccccEEEEEcccTTTcccHHHHHHHHTTcccccccHHHHHHHHcHHHHHHHHHTTTcccccEEEEcTTGHTTHGGGccHHHHHHHHcccEEEEEccccTTTTEEEEccHHHHHHHHHHHTTTcccEEEEEccccccEEEEEEEEccccEEEEETcccccccccHHHHTTccTTcEEEcccccHHHHHHHHHHHHHHHHHTTccEEEEEEEEETTccEEEEEEEccccccTTcGGGTGGGGGTccHHHHHHHHHHHHHHH DISOP:02AL 1-1,312-313| PSIPRED ccEEEEEEEcccHHHHHHHHHHHHHHHHHHHHccccEEEEccccHHHHHHHHHccccEEEEEccccccccHHHHHHHHHccccEEcccHHHHHHHccHHHHHHHHHHcccccccccEEcHHHccccccHHHHHHHHHHccccEEEEEcccccccEEEEEccHHHHHHHHHHHHHHccEEEEEEccccEEEEEEEEEccccEEEEEEEEccccccccHHHHcccccEEEEccccccHHHHHHHHHHHHHHHHHcccccEEEEEEEEEccEEEEEEEcccccccHHHHHHHHHHHccccHHHHHHHHHHHHHcc //