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Desulfotomaculum reducens MI-1 (dred0)
Gene : ABO50406.1
DDBJ      :             DNA mismatch repair protein MutL
Swiss-Prot:MUTL_DESRM   RecName: Full=DNA mismatch repair protein mutL;

Homologs  Archaea  18/68 : Bacteria  748/915 : Eukaryota  195/199 : Viruses  0/175   --->[See Alignment]
a.27.1d.122.1d.14.1d.292.1
:640 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   4->307 1nhjA PDBj 2e-57 41.1 %
:RPS:PDB   3->326 1b63A PDBj 4e-30 40.4 %
:RPS:PDB   339->445 2cmzB PDBj 2e-04 8.7 %
:RPS:SCOP  4->200 1b62A2  d.122.1.2 * 1e-66 49.7 %
:RPS:SCOP  214->326 1b62A1  d.14.1.3 * 3e-26 28.8 %
:RPS:SCOP  313->354 1u0bB1  a.27.1.1 * 3e-04 23.8 %
:RPS:SCOP  452->640 1x9zA  d.292.1.1 * 5e-32 17.5 %
:HMM:SCOP  1->216 1b63A2 d.122.1.2 * 2.9e-52 35.2 %
:HMM:SCOP  190->327 1h7sA1 d.14.1.3 * 7.1e-34 39.7 %
:HMM:SCOP  451->640 1x9zA_ d.292.1.1 * 8.6e-50 44.8 %
:RPS:PFM   212->326 PF01119 * DNA_mis_repair 1e-22 40.0 %
:RPS:PFM   458->595 PF08676 * MutL_C 2e-21 41.9 %
:HMM:PFM   458->597 PF08676 * MutL_C 9e-37 43.3 134/142  
:HMM:PFM   211->326 PF01119 * DNA_mis_repair 2.8e-36 39.7 116/119  
:HMM:PFM   20->88 PF02518 * HATPase_c 9.6e-13 29.4 68/111  
:BLT:SWISS 1->640 MUTL_DESRM 0.0 100.0 %
:PROS 94->100|PS00058|DNA_MISMATCH_REPAIR_1

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABO50406.1 GT:GENE ABO50406.1 GT:PRODUCT DNA mismatch repair protein MutL GT:DATABASE GIB00494CH01 GT:ORG dred0 GB:ACCESSION GIB00494CH01 GB:LOCATION complement(2067779..2069701) GB:FROM 2067779 GB:TO 2069701 GB:DIRECTION - GB:PRODUCT DNA mismatch repair protein MutL GB:NOTE TIGRFAM: DNA mismatch repair protein MutL PFAM: ATP-binding region, ATPase domain protein domain protein; DNA mismatch repair protein, C-terminal domain protein KEGG: sth:STH1748 DNA mismatch repair protein GB:PROTEIN_ID ABO50406.1 GB:DB_XREF GI:134052435 InterPro:IPR002099 InterPro:IPR003594 InterPro:IPR013507 LENGTH 640 SQ:AASEQ MSNITILDEATANKIAAGEVVERPVSVVKELVENSLDAGANRISVELTQGGITGIKVVDNGYGMPAEDVQLCFLRHATSKIKRAEDLNSILTLGFRGEALPSIAAVSKVTLTTRTEDELAGTTMQIEGGYMQNVVPTGCPVGTIIEIKDLFFNTPARRKFLKTANAETSQVSDLITRLAMARPDVRFELRSGNRVLFSSPGTGSLKDTAAVIFGLDNVRSMLEIGYQGKLLSVAGLISKPVLTRASRHYQNFFINGRYIRSGFLSSILQQAYDTLIPAGRFPIAILHIDIDPTQVDVNVHPTKMEIRMAREGEIQEELLAALSDSLNVPTAITGLWEIMPGRTKNTATDQRAENLEVKPDSKEKELQPKESQHPRLVACDLPSGKIMPPRHDQEQLHFSSRRIAPVRGKNSLLPDEGSSINREEIPPVVDVKEQQLKENPNTYQPAETLGFPVLVPAGQVPPTYVLAHGEGGLYIIDQHAAHERVLYEKYLYLLGNYVEAQMLLEPLTLEIPHHEAQLIIKHIVDFNELGFILEHFGGDTFLLRGVPTNAITEPKEVFLDLLARLQENPSQKVEKNLVLDHLAAAMACRDAVKSGQHFSAVETKALLDGLARCQKPYTCPHGRPTLIQISQEELKKRFKR GT:EXON 1|1-640:0| SW:ID MUTL_DESRM SW:DE RecName: Full=DNA mismatch repair protein mutL; SW:GN Name=mutL; OrderedLocusNames=Dred_1884; SW:KW Complete proteome; DNA damage; DNA repair. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->640|MUTL_DESRM|0.0|100.0|640/640| GO:SWS:NREP 2 GO:SWS GO:0006974|"GO:response to DNA damage stimulus"|DNA damage| GO:SWS GO:0006281|"GO:DNA repair"|DNA repair| PROS 94->100|PS00058|DNA_MISMATCH_REPAIR_1|PDOC00057| BL:PDB:NREP 1 BL:PDB:REP 4->307|1nhjA|2e-57|41.1|304/333| RP:PDB:NREP 2 RP:PDB:REP 3->326|1b63A|4e-30|40.4|324/333| RP:PDB:REP 339->445|2cmzB|2e-04|8.7|104/410| RP:PFM:NREP 2 RP:PFM:REP 212->326|PF01119|1e-22|40.0|115/119|DNA_mis_repair| RP:PFM:REP 458->595|PF08676|2e-21|41.9|136/146|MutL_C| HM:PFM:NREP 3 HM:PFM:REP 458->597|PF08676|9e-37|43.3|134/142|MutL_C| HM:PFM:REP 211->326|PF01119|2.8e-36|39.7|116/119|DNA_mis_repair| HM:PFM:REP 20->88|PF02518|9.6e-13|29.4|68/111|HATPase_c| GO:PFM:NREP 3 GO:PFM GO:0005524|"GO:ATP binding"|PF01119|IPR013507| GO:PFM GO:0006298|"GO:mismatch repair"|PF01119|IPR013507| GO:PFM GO:0030983|"GO:mismatched DNA binding"|PF01119|IPR013507| RP:SCP:NREP 4 RP:SCP:REP 4->200|1b62A2|1e-66|49.7|197/216|d.122.1.2| RP:SCP:REP 214->326|1b62A1|3e-26|28.8|111/113|d.14.1.3| RP:SCP:REP 313->354|1u0bB1|3e-04|23.8|42/146|a.27.1.1| RP:SCP:REP 452->640|1x9zA|5e-32|17.5|177/182|d.292.1.1| HM:SCP:REP 1->216|1b63A2|2.9e-52|35.2|216/218|d.122.1.2|1/1|ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase| HM:SCP:REP 190->327|1h7sA1|7.1e-34|39.7|131/134|d.14.1.3|1/1|Ribosomal protein S5 domain 2-like| HM:SCP:REP 451->640|1x9zA_|8.6e-50|44.8|181/0|d.292.1.1|1/1|DNA mismatch repair protein MutL| OP:NHOMO 1576 OP:NHOMOORG 961 OP:PATTERN ------------------------11112121-----------1111111111--------------- 111-------------------------------------------------------------------------------21-12-111111111111111111111111111111111111111111111111111111111211111111111------11111111------------111111111111111111111111111111111111111111111111111111111-11-1111111111111111111111111111111-1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111112112-11111111111111111111111111111111111111--11111112111111111111111111111111111111112111111111111111111111111111-------------------------111111111111111111111111111111111-1111111-11111111111111111111-1111111111111-11111111111111111111111111111111111111-111111111111--31111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111--1111111111111111-11-------------------------1111111111111 2212233-52233333333333343333323333322333333233233333333334333332343343443333424443333322-233322233332224312252976445833343446E3A2b*6-H8B3442A346334343513B455344892854-223852543143G2222232323322232213 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 436 STR:RPRED 68.1 SQ:SECSTR HcccccccHHHHHHHHHHHHcccHHHHHHHHHHHHHHTTccEEEEEEEGGGTcEEEEEEccccccGGGHHHHHcTTcccccccHHHHHTcccccccccHHHHHHTTcEEEEEEEcTTcccEEEEEEETTTTEEEEEEccccEEEEEEEcTTTTcHHHHHTcccHHHHHHHHHHHHHHHHHHcTTcEEEETEEEEEEccccTTccTHHHHHHHHcHHHHHHEEEEEEEETTEEEEEEEEcGGGccTTGGGcEEEEETEEcccHHHHHHHHHHHHHHccccccccEEEEEEccGGGEEcTTcTTccccEETTHHHHHHHHHHHHHHHTHHHHHH######EccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTccccHHHHHHHcccccEEEEEEEEEEEEEEEEEEEEcccEEcccEEEETTcccEEEc###ccccEEETTEEEc################################################################################################################################################################################################### DISOP:02AL 1-1,133-137,336-451| PSIPRED ccccEEccHHHHHHHccccccccHHHHHHHHHHccHHccccEEEEEEEcccEEEEEEEEccccccHHHHHHHcccccccccccccccccEEEcccccHHHHHHHccEEEEEEEEEccccEEEEEEEEccEEEEEEEcccccccEEEEEEcccccHHHHHHHcccHHHHHHHHHHHHHHHHHccccEEEEEEccEEEEEEcccccHHHHHHHHHcHHHHHHHEEEEEEcccEEEEEEEcccccccccccEEEEEEccEEEccHHHHHHHHHHHHHHccccccEEEEEEEEccHHHEEEEEcccccEEEEccHHHHHHHHHHHHHHHHcccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccHHHccccccccHHHHccccccccccccccccccEEEEEEcccEEEEEEccEEEEEEEHHHHHHHHHHHHHHHHccccccccccccEEEEccHHHHHHHHHHHHHHHHcccEEEEccccEEEEEEccccccccHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHcccccccccccEEEEEEcHHHHHHHccc //