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Francisella tularensis subsp. mediasiatica FSC147 (ftul2)
Gene : ACD30124.1
DDBJ      :             3-hydroxyisobutyrate dehydrogenase family protein
Swiss-Prot:             

Homologs  Archaea  27/68 : Bacteria  469/915 : Eukaryota  106/199 : Viruses  0/175   --->[See Alignment]
a.100.1c.2.1
:292 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   3->286 2uyyD PDBj 2e-22 25.8 %
:RPS:PDB   4->288 3ckyC PDBj 3e-46 20.9 %
:RPS:SCOP  4->163 1vpdA2  c.2.1.6 * 1e-22 20.8 %
:RPS:SCOP  166->289 3cumA1  a.100.1.1 * 2e-13 14.5 %
:HMM:SCOP  2->169 1pgjA2 c.2.1.6 * 1.9e-30 28.0 %
:HMM:SCOP  165->291 1vpdA1 a.100.1.1 * 2.7e-16 20.5 %
:RPS:PFM   4->156 PF03446 * NAD_binding_2 3e-11 27.5 %
:HMM:PFM   3->162 PF03446 * NAD_binding_2 1.7e-34 27.0 159/163  
:BLT:SWISS 5->288 3HIDH_MOUSE 8e-23 25.2 %
:PROS 66->78|PS00109|PROTEIN_KINASE_TYR

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ACD30124.1 GT:GENE ACD30124.1 GT:PRODUCT 3-hydroxyisobutyrate dehydrogenase family protein GT:DATABASE GIB00719CH01 GT:ORG ftul2 GB:ACCESSION GIB00719CH01 GB:LOCATION 7112..7990 GB:FROM 7112 GB:TO 7990 GB:DIRECTION + GB:PRODUCT 3-hydroxyisobutyrate dehydrogenase family protein GB:PROTEIN_ID ACD30124.1 GB:DB_XREF GI:187711827 LENGTH 292 SQ:AASEQ MSKQVGIIGLGNMGSVVIDHLLTSGYEIFIHNRTKAKAEKWLRNTQVVWCDSPKELAENCEIIICCLYNDIAAKNVYLSKNGLTSINLVNHTILDASTLSVSCFEQLNKVVTQNNGKLIDMPISGNPAALQEKRALIMLGATEEECKSFVHFLEALSNKILYLDIAGSALKEKLCINEMLFTQWFSYCEAMLLAENNGIKTEDFFKAMSQSVISSPLLVQRSQYFFGYNVNLSDLNMILKDIDIIEDFVNKSKTKVTLLQKFREVVEYAIKHDFTNQDFYGLYRAYKEIYKK GT:EXON 1|1-292:0| BL:SWS:NREP 1 BL:SWS:REP 5->288|3HIDH_MOUSE|8e-23|25.2|278/335| PROS 66->78|PS00109|PROTEIN_KINASE_TYR|PDOC00100| BL:PDB:NREP 1 BL:PDB:REP 3->286|2uyyD|2e-22|25.8|279/291| RP:PDB:NREP 1 RP:PDB:REP 4->288|3ckyC|3e-46|20.9|278/296| RP:PFM:NREP 1 RP:PFM:REP 4->156|PF03446|3e-11|27.5|149/160|NAD_binding_2| HM:PFM:NREP 1 HM:PFM:REP 3->162|PF03446|1.7e-34|27.0|159/163|NAD_binding_2| GO:PFM:NREP 3 GO:PFM GO:0004616|"GO:phosphogluconate dehydrogenase (decarboxylating) activity"|PF03446|IPR006115| GO:PFM GO:0006098|"GO:pentose-phosphate shunt"|PF03446|IPR006115| GO:PFM GO:0055114|"GO:oxidation reduction"|PF03446|IPR006115| RP:SCP:NREP 2 RP:SCP:REP 4->163|1vpdA2|1e-22|20.8|159/161|c.2.1.6| RP:SCP:REP 166->289|3cumA1|2e-13|14.5|124/134|a.100.1.1| HM:SCP:REP 2->169|1pgjA2|1.9e-30|28.0|164/0|c.2.1.6|1/1|NAD(P)-binding Rossmann-fold domains| HM:SCP:REP 165->291|1vpdA1|2.7e-16|20.5|127/0|a.100.1.1|1/1|6-phosphogluconate dehydrogenase C-terminal domain-like| OP:NHOMO 997 OP:NHOMOORG 602 OP:PATTERN ----111122222221-311111----1-1-------------1------1----1------11--11 111--1--------11111-11--12111111232311231--1---1-------1----------------------1---2111-------------------1-1----------------------------21122---12221-222----12211-11--111--111---1-11-----1----121111222222222222122222222222221111111211-------------------1---11-1---11--111111111-1---------------------------------------------1-11-------1-1-1---11------111--33-----1---------1111--------3253312232121--11-111113-11111221112-1--2224222331-2-1112-1--123111111113--211-------------------------------32222-122-433334311111447621221331B3643-411-22-1122211111-1--1--1111111111--1--2--11-1-1--1-1-1-111-111111--11-------------111-11-----11--222-121221111112111111111111---1--2------1111-1-2222232322-222232221222222222112111---1111111111111111-1111111---11111111111---------1111-22121112-1---------22222121112-4434-1-2222221212-121--1-1-21111111122222----------------2---1111--------1-1------------------1----------------2-1 ----11----1-21121----11-----------1-------------11-111-----------------------------------22-111------1-1-1-2423543431111-111321416F2-33512112-222121122123-32222234211-328-111111218--1-13475153125333- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 291 STR:RPRED 99.7 SQ:SECSTR cccEEEEEcccTTHHHHHHHHHHTTcEEEEEcccHHHHHHHHTTcEEcccccHHHHHHHccEEEEccccHHHHHHHHTcTTcHHHHccTTcEEEEcccccHHHHHHHHHHHHHTTcEEEEccEEcHHHHHHHTcEEEEEEccHHHHHHHHHHHHHHEEEEEEEEcTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTccHHHHHHHHHTcTTccHHHccTccccccccHHHccHHHHHHHHHHHHHHHHHHTcccHHHHHHHHHHHHHHHTTcTTccGGGGHHHHHHTcc# PSIPRED cccEEEEEEccHHHHHHHHHHHHcccEEEEEcccHHHHHHHHHHcccEEcccHHHHHHcccEEEEEcccHHHHHHHHHcHHHHHHccccccEEEEcccccHHHHHHHHHHHHHcccEEEEccccccHHHcccccEEEEEcccHHHHHHHHHHHHHHcccEEEEccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHccccHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHcc //