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Francisella tularensis subsp. mediasiatica FSC147 (ftul2)
Gene : gyrA
DDBJ      :gyrA         DNA gyrase, A subunit
Swiss-Prot:             

Homologs  Archaea  22/68 : Bacteria  910/915 : Eukaryota  187/199 : Viruses  9/175   --->[See Alignment]
b.68.10e.11.1
:868 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   30->522 1ab4A PDBj e-157 60.7 %
:BLT:PDB   537->843 1zi0B PDBj 5e-84 56.3 %
:RPS:PDB   30->522 1ab4A PDBj e-174 65.5 %
:RPS:PDB   528->643 3dwpC PDBj 4e-31 12.4 %
:RPS:PDB   651->743 3dwpC PDBj 1e-05 5.0 %
:RPS:PDB   741->845 3dwpC PDBj 2e-11 9.0 %
:RPS:SCOP  30->522 1ab4A  e.11.1.1 * e-175 65.5 %
:RPS:SCOP  535->848 1wp5A  b.68.10.1 * e-101 29.8 %
:HMM:SCOP  2->526 1bjtA_ e.11.1.1 * 7.8e-181 57.4 %
:HMM:SCOP  534->859 1wp5A_ b.68.10.1 * 1.7e-107 46.7 %
:RPS:PFM   32->501 PF00521 * DNA_topoisoIV e-148 66.7 %
:RPS:PFM   795->843 PF03989 * DNA_gyraseA_C 6e-06 38.8 %
:HMM:PFM   32->500 PF00521 * DNA_topoisoIV 6.5e-156 52.6 420/426  
:HMM:PFM   538->584 PF03989 * DNA_gyraseA_C 3.4e-08 29.8 47/50  
:HMM:PFM   588->638 PF03989 * DNA_gyraseA_C 3.5e-08 25.0 48/50  
:HMM:PFM   646->690 PF03989 * DNA_gyraseA_C 1e-09 22.2 45/50  
:HMM:PFM   694->741 PF03989 * DNA_gyraseA_C 1.5e-20 50.0 48/50  
:HMM:PFM   746->789 PF03989 * DNA_gyraseA_C 8.7e-13 30.2 43/50  
:HMM:PFM   795->842 PF03989 * DNA_gyraseA_C 3.3e-17 41.7 48/50  
:BLT:SWISS 1->842 GYRA_PSEAE 0.0 60.0 %
:REPEAT 3|681->732|733->781|782->834

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ACD30376.1 GT:GENE gyrA GT:PRODUCT DNA gyrase, A subunit GT:DATABASE GIB00719CH01 GT:ORG ftul2 GB:ACCESSION GIB00719CH01 GB:LOCATION 359184..361790 GB:FROM 359184 GB:TO 361790 GB:DIRECTION + GB:GENE gyrA GB:PRODUCT DNA gyrase, A subunit GB:PROTEIN_ID ACD30376.1 GB:DB_XREF GI:187712079 GB:GENE:GENE gyrA LENGTH 868 SQ:AASEQ MSIITKESSSINIEKELKQSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNELSNYYNRPYKKSARVVGDVIGKYHPHGDTAVYDTIVRMAQPFSLRYTLVDGQGNFGSVDGDSPAAMRYTEIRMEKLTHELLIDIDKETVDFSPNYDNTELVPDVLPTRVPNLLVNGSSGIAVGMATNIPPHNMTEVINGTIALIDNPNLTIEELIEYIPAPDFPTGSYINGTDGILEAYKTGRGRVIMRAKADIHEDEASGKAQIIVTEIPYQVNKAKLVEKIAELVKDKKVAGISELRDESDKDGIRVVIDLKRDESPEVVLNTLYAQTQLQCSFGINMVALSDNRPKLLNLKEILEQFIKHRKEVVTRRTIFELRKSKERAHILEGLLLSLANIDEMIELIKASPSPADAKESMLARSWNGSMVKSMLEGVDVKMYRKETLASHYGIQVDSSYNLTEEQADAILALRLHRLTGLEQDKIVNEFKELIDRIKYLISILSDIKELIRVVKDELVEIRDNYGDQRKSEIIESRLDLTREDLIAEEDMVVTLSMDGYVKTQPLSMYNAQKRGGVGKSATKTKEEDSIFKLMLASTHDTMLCFSSLGRVYWSKVYDFPVASRISKGRPINNILPLEKDERITAMMPISQFNEGWYVFMATKLGRVKKVDLSEFARPRSTGKIAIGLNDGDELSYVALTDGNKQIMMFSDAGKAIRFDESDVRAMGRSAAGVTGMRLHHNQKIVSVIVTNPDEGIVLAATENGYGKRTAVSEYRKTKRASQGVIAISTSERNGKVVVAALVENDEDIVMITDNGTLVRTSSDEVRECGRSAQGVRLINLRNNEKLISLKVVKQDDVEDNQDIENNEDIESSDVTVQSE GT:EXON 1|1-868:0| BL:SWS:NREP 1 BL:SWS:REP 1->842|GYRA_PSEAE|0.0|60.0|839/923| NREPEAT 1 REPEAT 3|681->732|733->781|782->834| BL:PDB:NREP 2 BL:PDB:REP 30->522|1ab4A|e-157|60.7|476/477| BL:PDB:REP 537->843|1zi0B|5e-84|56.3|295/296| RP:PDB:NREP 4 RP:PDB:REP 30->522|1ab4A|e-174|65.5|476/477| RP:PDB:REP 528->643|3dwpC|4e-31|12.4|113/120| RP:PDB:REP 651->743|3dwpC|1e-05|5.0|93/120| RP:PDB:REP 741->845|3dwpC|2e-11|9.0|104/120| RP:PFM:NREP 2 RP:PFM:REP 32->501|PF00521|e-148|66.7|430/434|DNA_topoisoIV| RP:PFM:REP 795->843|PF03989|6e-06|38.8|49/50|DNA_gyraseA_C| HM:PFM:NREP 7 HM:PFM:REP 32->500|PF00521|6.5e-156|52.6|420/426|DNA_topoisoIV| HM:PFM:REP 538->584|PF03989|3.4e-08|29.8|47/50|DNA_gyraseA_C| HM:PFM:REP 588->638|PF03989|3.5e-08|25.0|48/50|DNA_gyraseA_C| HM:PFM:REP 646->690|PF03989|1e-09|22.2|45/50|DNA_gyraseA_C| HM:PFM:REP 694->741|PF03989|1.5e-20|50.0|48/50|DNA_gyraseA_C| HM:PFM:REP 746->789|PF03989|8.7e-13|30.2|43/50|DNA_gyraseA_C| HM:PFM:REP 795->842|PF03989|3.3e-17|41.7|48/50|DNA_gyraseA_C| GO:PFM:NREP 10 GO:PFM GO:0003677|"GO:DNA binding"|PF00521|IPR002205| GO:PFM GO:0003918|"GO:DNA topoisomerase (ATP-hydrolyzing) activity"|PF00521|IPR002205| GO:PFM GO:0005524|"GO:ATP binding"|PF00521|IPR002205| GO:PFM GO:0005694|"GO:chromosome"|PF00521|IPR002205| GO:PFM GO:0006265|"GO:DNA topological change"|PF00521|IPR002205| GO:PFM GO:0003677|"GO:DNA binding"|PF03989|IPR006691| GO:PFM GO:0003916|"GO:DNA topoisomerase activity"|PF03989|IPR006691| GO:PFM GO:0005524|"GO:ATP binding"|PF03989|IPR006691| GO:PFM GO:0005694|"GO:chromosome"|PF03989|IPR006691| GO:PFM GO:0006265|"GO:DNA topological change"|PF03989|IPR006691| RP:SCP:NREP 2 RP:SCP:REP 30->522|1ab4A|e-175|65.5|476/477|e.11.1.1| RP:SCP:REP 535->848|1wp5A|e-101|29.8|309/323|b.68.10.1| HM:SCP:REP 2->526|1bjtA_|7.8e-181|57.4|472/760|e.11.1.1|1/1|Type II DNA topoisomerase| HM:SCP:REP 534->859|1wp5A_|1.7e-107|46.7|321/0|b.68.10.1|1/1|GyrA/ParC C-terminal domain-like| OP:NHOMO 1982 OP:NHOMOORG 1128 OP:PATTERN -----------------------111111111-----------1111111111--------111---- 1111211111111111112-12111211111122221111211122222222222222222222221222222222221111111111222212222112222222222222222222222222211111111111111111111122222222222222222222222222222222222221111111112222222222222222222222222222212222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222212122222222222221222222222111221122111121111111111112222222222222222222222222222222222-22223222222222222222222222222222222222222222222222222221111111111112222222222222111112222222222222222222222222222222232222222222222222222222221121222222222111222112121111111111111111111111122111111111111111111111111111222223222222222222222222222222221-2222211111122222222222222222-22222222222222222222222222222222222222222222222222221222222222222112222222222222222222222222112222222122222222222222222222222222222222222222222222222322222222222222222212222222222222221211112-22222222222222222231111111111122 221122114121112111111111111111111111111121111111111111111111111-1111-1111-1111111-111111-12111111111-2111111222122134112122122-319I2-42621-12-223221121113-422113912121111-44113222F2233232131233443222 ---1---------------1---------------111-1----------------------------------------------------------------------------------------------------------------------------------111-- STR:NPRED 845 STR:RPRED 97.4 SQ:SECSTR HHHHHHHcccccccccccTHHHHHHHHHHcTTTcccTTTcccHHHHHHHHHHHHTTcccccccEEHHHHHHHHHHHTccccHHHHHHHHHHTTcTTTcccccEEEEcccccTTccccccTTTcEEEEcTTHHHHcTTTTTTcccEEEcTTcccEEEccccccccHHHHHcEEEccccccEEEccccHHHHHHHHHHHHHcTTccHHHHTTTccccccccccEEcccHHHHHHHHHcEEEEEEEcEEEEEcccccETTEEEEEEccTTccHHHHHHHHHHHHTTTcccccccEEEccccccccEEEcccHHHHcHHHHHHHHHHcTTEEEEEEEcEEEETTEEEEccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHcccHHHHHHHHHHccEEccGGGTTcccccccTTccTTcEEcHccEEccEEEccHHHHHHHHTccGGGGcHHHHHHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHccccccEEHHHHHHHHHHccGGGcccEEEEccGGGHHEEccTGGGHHHHHTTTcTTcEEEEEcccccGGGGGGcHHHHHHccEEEEEETTTTGGGTccHHHHHHHHHHHHHHHHcHHHHcTTccEccccccHHHTcccTTccccTTcccccccHcHHHHHHHHHHHHHHHHHHHHHHTccGGGccHHHHHHHHHHHHHHHHHHHcccEEEEEccccccccccccccEEEEEEEEEEEEEEETTEEEEEEEEEcTTccEEEEEEETTTccTTGGGHHHHHHHHHHHHHHccEEEETTccccHHHHHHcccEEEEEccccccccccccccccc####################### PSIPRED cccccccEEEEEHHHHHHHHHHHHHHHHHHHHccccHHccccHHHHHHHHHHHHccccccccHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHcccEEEccccccccccccccHHHHHHHHHHHHHHHHHHHHccccccccEEcccccEEcccEEcccccEEEEEccccEEEccccccccccHHHHHHHHHHHHHcccccHHHHHHHccccccccccccccHHHHHHHHHccccEEEEEEEEEEEEEcccccEEEEEEcccccccHHHHHHHHHHHHHccccccHHHHHHHcccccEEEEEEEcccccHHHHHHHHHHHccccEEEEEEEEEEEccccEEccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHccccccccHHHHHHccccccccccccccccccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHccccccccccccccccHHHccccccEEEEEcccccEEEEEcccccccccccccccccccccccEEEEEEEEEcccEEEEEEccccEEEEEHHHccccccccccEEEHHHcccccccEEEEEEEccccccccEEEEEEcccEEEEEEHHHHcccccccEEEEEcccccEEEEEEEcccccEEEEEEcccEEEEEEHHHccccccccccEEEEEEccccEEEEEEEEcccccEEEEEEcccccccccHHHccccccccccEEEEEEccccccEEEEEEEccccEEEEEEcccEEEEEEHHHcccccccccccEEEEEccccEEEEEEEEccccccccccccccccccccccccccc //