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Francisella tularensis subsp. mediasiatica FSC147 (ftul2)
Gene : hemE
DDBJ      :hemE         uroporphyrinogen decarboxylase
Swiss-Prot:DCUP_FRATM   RecName: Full=Uroporphyrinogen decarboxylase;         Short=URO-D;         Short=UPD;         EC=4.1.1.37;

Homologs  Archaea  11/68 : Bacteria  683/915 : Eukaryota  182/199 : Viruses  0/175   --->[See Alignment]
c.1.22
:344 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   5->343 3cyvA PDBj 2e-90 47.9 %
:RPS:PDB   2->343 2ejaB PDBj 3e-65 37.3 %
:RPS:SCOP  4->343 1jphA  c.1.22.1 * e-128 43.2 %
:HMM:SCOP  2->345 1uroA_ c.1.22.1 * 1e-110 41.8 %
:RPS:PFM   6->341 PF01208 * URO-D 6e-84 46.1 %
:HMM:PFM   3->342 PF01208 * URO-D 1e-121 41.6 334/343  
:BLT:SWISS 1->344 DCUP_FRATM 0.0 100.0 %
:PROS 18->27|PS00906|UROD_1
:PROS 137->153|PS00907|UROD_2

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ACD30209.1 GT:GENE hemE GT:PRODUCT uroporphyrinogen decarboxylase GT:DATABASE GIB00719CH01 GT:ORG ftul2 GB:ACCESSION GIB00719CH01 GB:LOCATION 119311..120345 GB:FROM 119311 GB:TO 120345 GB:DIRECTION + GB:GENE hemE GB:PRODUCT uroporphyrinogen decarboxylase GB:PROTEIN_ID ACD30209.1 GB:DB_XREF GI:187711912 GB:GENE:GENE hemE LENGTH 344 SQ:AASEQ MRKLFLDAFGEKKLDKPPVWIMRQAGRYLPEYRAVRAKFDNFMDMCRNADACCEVALHPLQRYDLDAAIVFSDILTIPEAMGMDLKFIKGTGPVFSEPIQSQKDLDKLKSIEDSIGSLDYVYNAVKTTSSAINVPLIGFTGSPWTLAAYMIEGSGSKQFNKLRKMMYANPQLMHSLLQRLADITIIYLLEQVKAGASSVMIFDTWGGILPLEHYKNFSLKYKEYIAKNVKQKINIPIVFFTKGGSNFFEEIKDKSCDGVGVDWSVTLKQARHRIGVGKVLQGNFDPAFLYGSKQSIRETVRANIEFIQSDKLNNYIVNLGHGIYPDIDPDSVRVMIDAIREFSA GT:EXON 1|1-344:0| SW:ID DCUP_FRATM SW:DE RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37; SW:GN Name=hemE; OrderedLocusNames=FTM_0110; SW:KW Complete proteome; Cytoplasm; Decarboxylase; Lyase;Porphyrin biosynthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->344|DCUP_FRATM|0.0|100.0|344/344| GO:SWS:NREP 4 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016831|"GO:carboxy-lyase activity"|Decarboxylase| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| GO:SWS GO:0006779|"GO:porphyrin biosynthetic process"|Porphyrin biosynthesis| PROS 18->27|PS00906|UROD_1|PDOC00705| PROS 137->153|PS00907|UROD_2|PDOC00705| BL:PDB:NREP 1 BL:PDB:REP 5->343|3cyvA|2e-90|47.9|336/352| RP:PDB:NREP 1 RP:PDB:REP 2->343|2ejaB|3e-65|37.3|332/336| RP:PFM:NREP 1 RP:PFM:REP 6->341|PF01208|6e-84|46.1|330/339|URO-D| HM:PFM:NREP 1 HM:PFM:REP 3->342|PF01208|1e-121|41.6|334/343|URO-D| GO:PFM:NREP 2 GO:PFM GO:0004853|"GO:uroporphyrinogen decarboxylase activity"|PF01208|IPR000257| GO:PFM GO:0006779|"GO:porphyrin biosynthetic process"|PF01208|IPR000257| RP:SCP:NREP 1 RP:SCP:REP 4->343|1jphA|e-128|43.2|336/357|c.1.22.1| HM:SCP:REP 2->345|1uroA_|1e-110|41.8|340/0|c.1.22.1|1/1|UROD/MetE-like| OP:NHOMO 1015 OP:NHOMOORG 876 OP:PATTERN -----------------------------1--------2111--------111--------111---- 1111111111111111111-111111111111111111111111111111111111111111111111111------------11111-----------111111111111111111111111111111111111111111---1111111111111111111111111111111111111111-1111--11111111111111111111111111111111111111111111111111111111111111-----------------------------------------------------------------------------------------------1------------2--11-------1111111-----111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111---1----------121111111111111--111111111111111111111111111111111111111111111111111111111--11111------11111111111111111-11111111111111111111111111111111111111111111111111111111111111111--1111111111111111111111-----11111111111111111111111111111111111111111111111111111111111111111111111111-111111-----------------------------------------------1- 11--111-1---11111111111111111-11111112211111111111111111111111111111-1111111112111111111-11111111111111111-13-231111--111111111315D1-3111111111111111111-111112111131112132--222234w4443332541423321113 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 342 STR:RPRED 99.4 SQ:SECSTR #ccHHHHHHTTccccccccccTTcccTTcHHHHHHHTTcccHHHHHHcHHHHHHHHHHHHHHHccccEEccccTTGGGGGGTcEEEEETTTEEEEEcccEcTTcGGGcccccccGGGGHHHHHHHHHHHHHccccEEEEEEcHHHHHHHHHTTTcccccHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHHHTTccEEEEEETTGGGccHHHHHHHTHHHHHHHHHHHHHHccccEEEEEccHHHHHHHHTTccccEEEccTTccHHHHHHHHHccccEEccccGGGGGccHHHHHHHHHHHHTTccccccccEEccccccccTTccHHHHHHHHHHHHTcc# DISOP:02AL 344-345| PSIPRED ccHHHHHHHcccccccccEEEEccccHHHHHHHHHHHHcccHHHHHccHHHHHHHHHHHHHHccccEEEEEHHHHHHHHHcccEEEEccccccccccccccHHHHHccccccccHHHHHHHHHHHHHHHHHHcccEEEEcccHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccEEEEEccHHccccHHHHHHHHHHHHHHHHHHHHHcccccEEEEccccHHHHHHHHHccccEEEEcccccHHHHHHHHcccEEEEccccHHHHcccHHHHHHHHHHHHHHHHHcccccEEEEEcccccccccHHHHHHHHHHHHHHcc //