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Francisella tularensis subsp. mediasiatica FSC147 (ftul2)
Gene : hemH
DDBJ      :hemH         ferrochelatase
Swiss-Prot:HEMH_FRATW   RecName: Full=Ferrochelatase;         EC=4.99.1.1;AltName: Full=Protoheme ferro-lyase;AltName: Full=Heme synthetase;

Homologs  Archaea  1/68 : Bacteria  578/915 : Eukaryota  174/199 : Viruses  0/175   --->[See Alignment]
c.92.1
:333 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   58->304 2po7A PDBj 2e-25 32.4 %
:RPS:PDB   9->329 2c8jA PDBj 3e-65 23.5 %
:RPS:SCOP  9->329 1ak1A  c.92.1.1 * 9e-67 21.8 %
:HMM:SCOP  7->329 1hrkA_ c.92.1.1 * 8.4e-96 45.0 %
:RPS:PFM   10->327 PF00762 * Ferrochelatase 1e-71 46.8 %
:HMM:PFM   10->328 PF00762 * Ferrochelatase 2.8e-106 41.2 308/316  
:BLT:SWISS 1->333 HEMH_FRATW 0.0 100.0 %
:PROS 197->216|PS00534|FERROCHELATASE

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ACD31156.1 GT:GENE hemH GT:PRODUCT ferrochelatase GT:DATABASE GIB00719CH01 GT:ORG ftul2 GB:ACCESSION GIB00719CH01 GB:LOCATION 1397246..1398247 GB:FROM 1397246 GB:TO 1398247 GB:DIRECTION + GB:GENE hemH GB:PRODUCT ferrochelatase GB:PROTEIN_ID ACD31156.1 GB:DB_XREF GI:187712859 GB:GENE:GENE hemH LENGTH 333 SQ:AASEQ MQQYSSKYNKQAILLVNLGTPDNYDTKSIKRYLKEFLSDPRVIEANPVLWKIILNLIILPIRAKKNVHTYKTVWNKQHNKSPLLFYTENLADKLDKKLDNYIVDYAMRYGNPSIESKIKSLQDQGATEIIIFPLYPQYSATTTATVYDEVYRVLSKLRWQPTIKGINPYYDNKFHIQTISQQIKEHLKKLDSTPDTVLFSFHGLPKEYFDKGDPYYCHCYKTYRLVKEELQNEYPNIDFELSFQSRFGPKKWLEPYTTVKLEEFAKQNKSVVVIAPGFSADCLETLEELAISEKENFIKKGGKEFSLIPCLNDSNQHVDMLYNIIDEEICLKK GT:EXON 1|1-333:0| SW:ID HEMH_FRATW SW:DE RecName: Full=Ferrochelatase; EC=4.99.1.1;AltName: Full=Protoheme ferro-lyase;AltName: Full=Heme synthetase; SW:GN Name=hemH; OrderedLocusNames=FTW_1172; SW:KW Complete proteome; Cytoplasm; Heme biosynthesis; Iron; Lyase;Metal-binding; Porphyrin biosynthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->333|HEMH_FRATW|0.0|100.0|333/333| GO:SWS:NREP 5 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006783|"GO:heme biosynthetic process"|Heme biosynthesis| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0006779|"GO:porphyrin biosynthetic process"|Porphyrin biosynthesis| PROS 197->216|PS00534|FERROCHELATASE|PDOC00462| BL:PDB:NREP 1 BL:PDB:REP 58->304|2po7A|2e-25|32.4|241/359| RP:PDB:NREP 1 RP:PDB:REP 9->329|2c8jA|3e-65|23.5|293/311| RP:PFM:NREP 1 RP:PFM:REP 10->327|PF00762|1e-71|46.8|308/315|Ferrochelatase| HM:PFM:NREP 1 HM:PFM:REP 10->328|PF00762|2.8e-106|41.2|308/316|Ferrochelatase| GO:PFM:NREP 2 GO:PFM GO:0004325|"GO:ferrochelatase activity"|PF00762|IPR001015| GO:PFM GO:0006783|"GO:heme biosynthetic process"|PF00762|IPR001015| RP:SCP:NREP 1 RP:SCP:REP 9->329|1ak1A|9e-67|21.8|293/308|c.92.1.1| HM:SCP:REP 7->329|1hrkA_|8.4e-96|45.0|311/0|c.92.1.1|1/1|Chelatase| OP:NHOMO 822 OP:NHOMOORG 753 OP:PATTERN ---------------------------------------------------------1---------- ----------------------------------------------------------------------1--------111-11111------11---11111111121111111111111111-------------------1131111111111111111111111111111111111111-1-----1-11111111111111111122--11-111-----------11-------------------1---11-----111111----1-111--------11--------------------------------------------------------------1------------1--------11-1111-----111111111111111111111111-111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111---1----------11111111111111---11-111111111111111111111111111111111111222211222222222221--11111------11111111111111111-1111111111111111111-111111111111111111111111111111111111111111111--1111111111111111111111-111-1111111111111111111111111111111111111111111111111111111111111111111111111111111-1-----------------------------------------------1- 11--11--31--22111111111111111111111111-11-1-1--111111111111111111111-1111111111111111111-11111111111111111-14121111111--11112211-2A2-21311-11111111-1-1-121211211-111113111--11111191111132241221121111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 321 STR:RPRED 96.4 SQ:SECSTR ########EEEEEEEEEccccccGGGGGHHHHHHHHTTTccccHHHHccHHHHHHHHccHHHHHHHHHHHHHTTccTTccHHHHHHHHHHHHHHHHHHHEEEEEEEEccccccHHHHHHHHHHTTccEEEEEEccccccHHHHHHTHHHHHHHHHHHccccEEEEccccTTcHHHHHHHHHHHHHHHHTccHHHEEEEEEEEcccTHHHHHTccHHHHHHHHHHHHHHHHTcccTcccEEEEEEccccccccccccHHHHHHHHHHHTcEEEEEcTTcccccHHHHTTTTTHHHHHHHHHTccEEEcccccTTcHHHHHHHHHHHHHHH#### PSIPRED ccccccccccEEEEEEEccccccccHHHHHHHHHHHccccccccccHHHHHHHHHHHHHccccHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHcccccEEEEEccccccHHHHHHHHHHHcccEEEEEEcccHHHHccHHHHHHHHHHHHHHccccccEEEEccccccHHHHHHHHHHHHHHHHHccccccEEEEEcccccHHHHHccccHHHHHHHHHHHHHHHHccccccccEEEEEEccccccccccccHHHHHHHHHHccccEEEEEcHHHHHHHHHHHHHHHHHHHHHHHccccEEEEcccccccHHHHHHHHHHHHHHHHHcc //