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Francisella tularensis subsp. mediasiatica FSC147 (ftul2)
Gene : hisS
DDBJ      :hisS         histidyl-tRNA synthetase
Swiss-Prot:SYH_FRATM    RecName: Full=Histidyl-tRNA synthetase;         EC=6.1.1.21;AltName: Full=Histidine--tRNA ligase;         Short=HisRS;

Homologs  Archaea  66/68 : Bacteria  865/915 : Eukaryota  107/199 : Viruses  0/175   --->[See Alignment]
c.23.6c.51.1d.104.1
:421 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   7->406 1kmmC PDBj 1e-99 50.4 %
:RPS:PDB   4->420 1adjA PDBj 4e-53 36.1 %
:RPS:SCOP  16->311 1usyA  d.104.1.1 * 1e-57 20.3 %
:RPS:SCOP  300->394 1e1cB2  c.23.6.1 * 6e-17 15.1 %
:HMM:SCOP  3->325 1kmmA2 d.104.1.1 * 1.1e-94 38.8 %
:HMM:SCOP  324->419 1kmmA1 c.51.1.1 * 1e-14 34.0 %
:RPS:PFM   35->160 PF00587 * tRNA-synt_2b 1e-11 37.1 %
:RPS:PFM   181->262 PF03717 * PBP_dimer 5e-04 32.1 %
:RPS:PFM   357->420 PF03129 * HGTP_anticodon 2e-06 33.3 %
:HMM:PFM   25->181 PF00587 * tRNA-synt_2b 6.2e-24 22.1 154/173  
:HMM:PFM   346->420 PF03129 * HGTP_anticodon 1.6e-11 23.0 74/94  
:BLT:SWISS 1->421 SYH_FRATM 0.0 100.0 %
:TM
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ACD30214.1 GT:GENE hisS GT:PRODUCT histidyl-tRNA synthetase GT:DATABASE GIB00719CH01 GT:ORG ftul2 GB:ACCESSION GIB00719CH01 GB:LOCATION 125531..126796 GB:FROM 125531 GB:TO 126796 GB:DIRECTION + GB:GENE hisS GB:PRODUCT histidyl-tRNA synthetase GB:PROTEIN_ID ACD30214.1 GB:DB_XREF GI:187711917 GB:GENE:GENE hisS LENGTH 421 SQ:AASEQ MSKLTIVRGFNDVLPLDSYKWQLLESKVKLILDRYNYSETRLPIVERSELFHRSVGESSDIVSKETYDFQDRNGDSLTLRPEGTAGCVRMVIENNLATRGQTQKLWYCGPMFRYERPQKGRYRQFYQLGVEAYGFDGIAIDLEVIAIAWSLFKELGISEYVTLELNSLGSSLNRQEYTQALLQYLKPYHAELDEDSIKRLDKNPLRILDSKIEKTQKILANAPKLIDFIDHDLRLRFKQTCQYLDALGVRYKLNENLVRGLDYYTGLVFEWTTDKLGSQSAICAGGRYDGLVENLGGQKTAAIGFAIGMERLLLLLEDLGKLPNQDNACDVFFILDSAQLHQSLAIVENIRQELPQLKIDMDLKFGSFKSQFKKADKSGAKVAIIIGQDELDNGFAGIKFLQQNEEQQQVAFNELINFLER GT:EXON 1|1-421:0| SW:ID SYH_FRATM SW:DE RecName: Full=Histidyl-tRNA synthetase; EC=6.1.1.21;AltName: Full=Histidine--tRNA ligase; Short=HisRS; SW:GN Name=hisS; OrderedLocusNames=FTM_0116; SW:KW Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm;Ligase; Nucleotide-binding; Protein biosynthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->421|SYH_FRATM|0.0|100.0|421/421| GO:SWS:NREP 6 GO:SWS GO:0004812|"GO:aminoacyl-tRNA ligase activity"|Aminoacyl-tRNA synthetase| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006412|"GO:translation"|Protein biosynthesis| TM:NTM 1 TM:REGION 132->154| SEG 312->322|llllledlgkl| BL:PDB:NREP 1 BL:PDB:REP 7->406|1kmmC|1e-99|50.4|365/387| RP:PDB:NREP 1 RP:PDB:REP 4->420|1adjA|4e-53|36.1|413/420| RP:PFM:NREP 3 RP:PFM:REP 35->160|PF00587|1e-11|37.1|124/170|tRNA-synt_2b| RP:PFM:REP 181->262|PF03717|5e-04|32.1|81/188|PBP_dimer| RP:PFM:REP 357->420|PF03129|2e-06|33.3|63/91|HGTP_anticodon| HM:PFM:NREP 2 HM:PFM:REP 25->181|PF00587|6.2e-24|22.1|154/173|tRNA-synt_2b| HM:PFM:REP 346->420|PF03129|1.6e-11|23.0|74/94|HGTP_anticodon| GO:PFM:NREP 10 GO:PFM GO:0000166|"GO:nucleotide binding"|PF00587|IPR002314| GO:PFM GO:0004812|"GO:aminoacyl-tRNA ligase activity"|PF00587|IPR002314| GO:PFM GO:0005524|"GO:ATP binding"|PF00587|IPR002314| GO:PFM GO:0005737|"GO:cytoplasm"|PF00587|IPR002314| GO:PFM GO:0006412|"GO:translation"|PF00587|IPR002314| GO:PFM GO:0006418|"GO:tRNA aminoacylation for protein translation"|PF00587|IPR002314| GO:PFM GO:0008658|"GO:penicillin binding"|PF03717|IPR005311| GO:PFM GO:0004812|"GO:aminoacyl-tRNA ligase activity"|PF03129|IPR004154| GO:PFM GO:0005524|"GO:ATP binding"|PF03129|IPR004154| GO:PFM GO:0006412|"GO:translation"|PF03129|IPR004154| RP:SCP:NREP 2 RP:SCP:REP 16->311|1usyA|1e-57|20.3|261/275|d.104.1.1| RP:SCP:REP 300->394|1e1cB2|6e-17|15.1|93/163|c.23.6.1| HM:SCP:REP 3->325|1kmmA2|1.1e-94|38.8|322/322|d.104.1.1|1/1|Class II aaRS and biotin synthetases| HM:SCP:REP 324->419|1kmmA1|1e-14|34.0|94/99|c.51.1.1|1/1|Class II aaRS ABD-related| OP:NHOMO 1226 OP:NHOMOORG 1038 OP:PATTERN --111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-11111111111111111111------------------11---11-1111--------11111112211111-1111--1-11111111111111111111111111111111111222222222222222221111111111122-11121121122111111111122112233333232123333332221233322222111221223111111111111111111111111111111111122111111211111111111211111111111111111111111111211112111113123222221212221112111212112122112221222222221111111111111111--1--1111111111111111111-1111111-1111111111-11111111-111111111111111111111111-1111111111111111111111111111111-1111-111111111111111111111111111111111211111111121211111111211111111111211111111111111111112221221121111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111311111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111 1-1122--3111-111-1-1111-1--11-111---11-1111---1111-1--22---1---11111111--11-1--11-111--------------11--2-1-1221------111--1-111---2---21----2------11-11-21-1-213--1-----1-----1-11P2221222422221123222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 421 STR:RPRED 100.0 SQ:SECSTR TGGccccTTcccccHHHHHHHHHHHHHHHHHHHHTTcEEcccccEEEHHHHHHHHcTTcHHHHHcccEEEcTTccEEEEccccHHHHHHHHHHTTGGGccccEEEEEEEEEEcccccccccccEEEEEEEEEEccccHHHHHHHHHHHHHHHHHTTcccccEEEEEEcccHHHHHHHHHHHHHHHGGGGGGccHHHHHHTTccGGGGTTcccHHHHHHHHTcccGGGGccHHHHHHHHHHHHHHHHTTccEEEcccccccccccccEEEEEEccccccccEEEEEEEcTTHHHHTTcccccEEEEEEEHHHHHHHHHHTTccccccccccEEEEEccHHHHHHHHHHHHHHTTHHTccEEEccccccHHHHHHHHHHTTccEEEEEcHHHHHHTEEEEEETTTTccEEEEETTHHHHHHHc PSIPRED ccccccccccccccccHHHHHHHHHHHHHHHHHHcccEEEEccccccHHHHHHcccccccccccccEEEEEccccEEEEccccHHHHHHHHHHcccccccccEEEEEEEEEEcccccccccccEEEEEEEEEEccccHHHHHHHHHHHHHHHHHccccccEEEEEccccccccHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHcccEEEEEccccccccccccEEEEEEEccccccEEEEEcccHHHHHHHHccccccEEEEcccHHHHHHHHHHccccccccccccEEEEccHHHHHHHHHHHHHHHHcccccEEEEEEccccHHHHHHHHHHccccEEEEEcHHHHHccEEEEEEcccccEEEEEcHHHHHHHHcc //