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Francisella tularensis subsp. mediasiatica FSC147 (ftul2)
Gene : ileS
DDBJ      :ileS         isoleucyl-tRNA synthetase
Swiss-Prot:SYI_FRATM    RecName: Full=Isoleucyl-tRNA synthetase;         EC=6.1.1.5;AltName: Full=Isoleucine--tRNA ligase;         Short=IleRS;

Homologs  Archaea  68/68 : Bacteria  912/915 : Eukaryota  197/199 : Viruses  0/175   --->[See Alignment]
a.128.1a.27.1b.51.1c.26.1
:935 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   3->920 1ffyA PDBj 0.0 41.7 %
:RPS:PDB   18->860 2bteA PDBj e-115 15.8 %
:RPS:SCOP  5->197 1n1bA2  a.128.1.3 * 2e-37 9.8 %
:RPS:SCOP  204->402 1ffyA2  b.51.1.1 * 1e-47 38.2 %
:RPS:SCOP  398->647 1li5A2  c.26.1.1 * 5e-24 14.5 %
:RPS:SCOP  649->924 1ffyA1  a.27.1.1 * 5e-76 35.1 %
:HMM:SCOP  2->648 1ffyA3 c.26.1.1 * 1.8e-133 36.1 %
:HMM:SCOP  649->925 1ffyA1 a.27.1.1 * 3.4e-66 34.6 %
:RPS:PFM   31->630 PF00133 * tRNA-synt_1 e-144 44.0 %
:RPS:PFM   682->817 PF08264 * Anticodon_1 3e-16 32.6 %
:HMM:PFM   28->637 PF00133 * tRNA-synt_1 3e-217 42.4 587/601  
:HMM:PFM   682->839 PF08264 * Anticodon_1 2e-27 25.5 149/152  
:HMM:PFM   896->922 PF06827 * zf-FPG_IleRS 1.5e-08 37.0 27/30  
:BLT:SWISS 1->935 SYI_FRATM 0.0 100.0 %
:PROS 58->69|PS00178|AA_TRNA_LIGASE_I
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ACD30520.1 GT:GENE ileS GT:PRODUCT isoleucyl-tRNA synthetase GT:DATABASE GIB00719CH01 GT:ORG ftul2 GB:ACCESSION GIB00719CH01 GB:LOCATION complement(546547..549354) GB:FROM 546547 GB:TO 549354 GB:DIRECTION - GB:GENE ileS GB:PRODUCT isoleucyl-tRNA synthetase GB:PROTEIN_ID ACD30520.1 GB:DB_XREF GI:187712223 GB:GENE:GENE ileS LENGTH 935 SQ:AASEQ MSDYKDTLNLPKTSFSMKGNLANKEPMILNKWEKQGIYKKIREHFAGREKFILHDGPPYANGSIHVGHAVNKILKDIIIKSKTLSGYDAPFTPTWDCHGLPIELQVEKKHGKAGQSISEDDFRKECRKYAKKQVEIQKKDFKRLGVLGDWEQPYLTINFDYEANMIRTLAKIIENGHLSKGFKPVHWCTDCGSALAEAEVEYADKVSPAIDVKFKIKDKDKLAQAFGLDSLNHDAFAIIWTTTPWTLPANQAIAVNNQLNYSLIKIEDFYIILAENLVEQTLKRYAIENAQIIATTTGNKLTGIIAEHPFYSRHVPILHGDHVTDDSGTGLVHTAPTHGVDDFTLGKEHNLSMEIFVKGNGCYSENTKLFAGEFIFKANDRIIELLGEKKRLMNSDKIKHSYPHCWRHKTPLMFRATPQWFISMEKQGLRDKALQAIKETSWAPSWGQARIEGMVKDRPDWCISRQRTWGVPLSLFIHKETEELHPNTIEILYKVAEKIEKDGIEAWFNADDCEFITETAQYKSVKDTLDVWFDSGSSSMCILDLDKRLSYPADLYLEGSDQHRGWFQTSLLVAMSAKGSQPYKEVFTHGFVVDEHGRKMSKSLGNVTSPQDIYNTLGADILRLWTASTDYKSEMAVSDQILKRTADTYRRLRNTARFLLSNLDGFNPVTDIIEFDKLVKLDQWAIAKTKEFQDKIIEAYDKYQTHTVAQLIHHFCSIEMGSFYLDIIKDRQYTAKTDGHPRKSAQTAIYHIVHALVRWMAPILSFTADEIWDATLKTTDLPIQLCEWYTGLKSFDQDAELDLEYWAKIQEIRSEVNRVLEIKRNEDVIKASLEAEITIYADKYNYKLLEKLGNELRFLLISSKADLKVIEESTSSSIAANIPGLLIEITKIEEPKCERCWHRSSTVGDNPQYKDICSRCVENITTEAGESREFA GT:EXON 1|1-935:0| SW:ID SYI_FRATM SW:DE RecName: Full=Isoleucyl-tRNA synthetase; EC=6.1.1.5;AltName: Full=Isoleucine--tRNA ligase; Short=IleRS; SW:GN Name=ileS; OrderedLocusNames=FTM_0503; SW:KW Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm;Ligase; Metal-binding; Nucleotide-binding; Protein biosynthesis; Zinc. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->935|SYI_FRATM|0.0|100.0|935/935| GO:SWS:NREP 7 GO:SWS GO:0004812|"GO:aminoacyl-tRNA ligase activity"|Aminoacyl-tRNA synthetase| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006412|"GO:translation"|Protein biosynthesis| PROS 58->69|PS00178|AA_TRNA_LIGASE_I|PDOC00161| SEG 210->221|idvkfkikdkdk| BL:PDB:NREP 1 BL:PDB:REP 3->920|1ffyA|0.0|41.7|897/917| RP:PDB:NREP 1 RP:PDB:REP 18->860|2bteA|e-115|15.8|802/876| RP:PFM:NREP 2 RP:PFM:REP 31->630|PF00133|e-144|44.0|575/593|tRNA-synt_1| RP:PFM:REP 682->817|PF08264|3e-16|32.6|135/153|Anticodon_1| HM:PFM:NREP 3 HM:PFM:REP 28->637|PF00133|3e-217|42.4|587/601|tRNA-synt_1| HM:PFM:REP 682->839|PF08264|2e-27|25.5|149/152|Anticodon_1| HM:PFM:REP 896->922|PF06827|1.5e-08|37.0|27/30|zf-FPG_IleRS| GO:PFM:NREP 12 GO:PFM GO:0000166|"GO:nucleotide binding"|PF00133|IPR002300| GO:PFM GO:0004812|"GO:aminoacyl-tRNA ligase activity"|PF00133|IPR002300| GO:PFM GO:0005524|"GO:ATP binding"|PF00133|IPR002300| GO:PFM GO:0005737|"GO:cytoplasm"|PF00133|IPR002300| GO:PFM GO:0006412|"GO:translation"|PF00133|IPR002300| GO:PFM GO:0006418|"GO:tRNA aminoacylation for protein translation"|PF00133|IPR002300| GO:PFM GO:0000166|"GO:nucleotide binding"|PF08264|IPR013155| GO:PFM GO:0004812|"GO:aminoacyl-tRNA ligase activity"|PF08264|IPR013155| GO:PFM GO:0005524|"GO:ATP binding"|PF08264|IPR013155| GO:PFM GO:0005737|"GO:cytoplasm"|PF08264|IPR013155| GO:PFM GO:0006412|"GO:translation"|PF08264|IPR013155| GO:PFM GO:0006418|"GO:tRNA aminoacylation for protein translation"|PF08264|IPR013155| RP:SCP:NREP 4 RP:SCP:REP 5->197|1n1bA2|2e-37|9.8|193/315|a.128.1.3| RP:SCP:REP 204->402|1ffyA2|1e-47|38.2|191/194|b.51.1.1| RP:SCP:REP 398->647|1li5A2|5e-24|14.5|249/299|c.26.1.1| RP:SCP:REP 649->924|1ffyA1|5e-76|35.1|268/273|a.27.1.1| HM:SCP:REP 2->648|1ffyA3|1.8e-133|36.1|443/451|c.26.1.1|1/1|Nucleotidylyl transferase| HM:SCP:REP 649->925|1ffyA1|3.4e-66|34.6|269/273|a.27.1.1|1/1|Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases| OP:NHOMO 3236 OP:NHOMOORG 1177 OP:PATTERN 22223222222222333322322233342323323222222222222323333233333333333222 3333222222222222222-2222222222222222222222222322222223323322332222222222222222333323423322222222212222222222322333333222222223322222222322233223332222222222222222222222222322222223232222333322334444444434444442333234443332433222222433333333334333332332332322223222332222222233222222222222222222222222222222222222222222222223332222223322322322222222322322333333334333222333323223323333322222332222223333333333212222222223324223332333223333322322222222222222232232322222222222222222222222222222223222222222222222223443222244442222222222222222222222222222233323222222222222223333333333333333333333333235233322322222222222222222232222333223232222333322233332222322212223222222223333222222222222-22222222222222222222222222322222222222222222222222222222222222222222322222222233234333323332333232222222222222222222222222222222333333332333333333333332222222222222232232222332223223222222223-22332323333322322223233433333222 4522444-82222223343333433344433333333333233333533432323334333333333314334333313333333344-3433333333333344423A5746464A334243464374n*51644343384363244325215433346CG46463745C74644344f4554446BC4554575745 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 935 STR:RPRED 100.0 SQ:SECSTR cTEccEEEEEEEEEEEEcccHHHHHHHHHHHHHHHTccccccccTcTTcEEEEEEccccccccccHHHHHHHHHHHHHHHHHHHTTcEEEcccccccccHHHHHHHHHEccTTTTHHHHHHTTccHHHHHHHHHHHHHHHHHHTTccccGGGcccTTcHHHHHHHHHHHHHHHHTTcEEEEEEEEEEETTTTEEEcGcccEEEEEEEEEEcGGGGHHHHHHTTTTccccHHHHHcEEEEEEccGGGGGGccEEEEcTTcTHHHHcccHHHHHHHHHHHHHHHHccHHHcHTTcTTccccEEEEEEEEcTTTccEEEEEEcTTccTTcTTcEEEEcGGGcHHHHHHHHHTTccccccEEccccEEcccGGGTTccHHHHHHHHHHHHHHHTcEEEEEEccccccccEEcccccHHccccEEEETTTEEEcccTTccccccccccHHHHccccccGGGGcHHHHEEEccccccEEEccTTHHHHTTcTTcccccccHHHHHHHccccEEEEcGGGTTTHHHHHHHHHHHTTcccccccccccEEccEEEEEEETTEEEccHHHHHHHcccccEEEHHHHHHTTcEEEEcTTccEEEEEcccccTTTTccccHHHHHHHccHHHHHHHHccccTTccEEEcHHHHHHHHHHHHHHHHHHHHTHHHHHTccccTcccccTTccTHHHHHHHHHHHHHHHHHHHHHTTcHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHTTTcHHHHHHHHHTTccccHHHGGGTccccccHHHHccccEEcEEEEETTEEEEEEEEcccccHHHHHHHHTTccccHHHHcccccEEEEETTTEEEEEcTHHHHHHHHHHHHHHHHHHHccTTccccccTHTcccccTTTccccccccccccccccEEEEccTTcEEEEEcTTT PSIPRED ccccccccccccccccccccHHHHHHHHHHHHHHcccccccccccccccEEEEEEccccccccccHHHHHHHHHHHHHHHHHHHcccEEccccccccccHHHHHHHHHHccccHHHccHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccEEcccHHHHHHHHHHHHHHHHcccEEcccEEEEccccccccccHHHHHccccccccccccccccccccHHHHccccccccccEEEEEcccccEEEcccEEEEcccccEEEEEEccccEEHHHHHHHHHHHHccccccEEEcccccccccccEEEccccccEEEEEEcccccccccccEEEEcccccHHHHHHHHHHcccEEEEEccccccccccHHHccccHHHccHHHHHHHHHcccEEccccccccccEEcccccEEEEEEHHHHHccccHHHHHHHHHHHHcccccccHHHHHHHHHHHccccccEEEEEcccccccccEEcccccEEEcccHHHHHHHHHHcccccccccccccHHHccccccccEEccccEEEEccccccHHHHccccHHccccEEEEEEEHHHHHHHHHHHHHHHHHHcccccHHHEEEEccEEccccccccccccccccHHHHHHHcccHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccccccHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHcccccccEEccccccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccEEEEEcccccHHHHHHHHHHHHHHHHHHccEEcccccccHHHHHHHcccEEEEEEcccccccccccccccccccccccccccHHHHHHHccccccccccc //