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Francisella tularensis subsp. mediasiatica FSC147 (ftul2)
Gene : ilvD
DDBJ      :ilvD         dihydroxy-acid dehydratase
Swiss-Prot:ILVD_FRATM   RecName: Full=Dihydroxy-acid dehydratase;         Short=DAD;         EC=4.2.1.9;

Homologs  Archaea  54/68 : Bacteria  742/915 : Eukaryota  117/199 : Viruses  0/175   --->[See Alignment]
c.8.2d.334.1
:560 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   84->525 2gp4A PDBj 2e-24 30.3 %
:RPS:PDB   34->292 2cwlB PDBj 4e-33 12.0 %
:RPS:PDB   339->525 3ejfA PDBj 8e-27 10.7 %
:RPS:SCOP  51->379 2gp4A2  d.334.1.1 * 9e-82 29.1 %
:RPS:SCOP  381->559 2gp4A1  c.8.2.2 * 4e-32 28.5 %
:HMM:SCOP  5->379 2gp4A2 d.334.1.1 * 1.1e-134 49.9 %
:HMM:SCOP  380->559 2gp4A1 c.8.2.2 * 3.7e-57 53.1 %
:RPS:PFM   37->554 PF00920 * ILVD_EDD e-141 49.2 %
:HMM:PFM   37->555 PF00920 * ILVD_EDD 2.5e-217 53.9 519/521  
:BLT:SWISS 1->560 ILVD_FRATM 0.0 100.0 %
:PROS 125->135|PS00886|ILVD_EDD_1
:PROS 466->477|PS00887|ILVD_EDD_2
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ACD31091.1 GT:GENE ilvD GT:PRODUCT dihydroxy-acid dehydratase GT:DATABASE GIB00719CH01 GT:ORG ftul2 GB:ACCESSION GIB00719CH01 GB:LOCATION complement(1302806..1304488) GB:FROM 1302806 GB:TO 1304488 GB:DIRECTION - GB:GENE ilvD GB:PRODUCT dihydroxy-acid dehydratase GB:PROTEIN_ID ACD31091.1 GB:DB_XREF GI:187712794 GB:GENE:GENE ilvD LENGTH 560 SQ:AASEQ MKKILNKYSRRLTEDKSQGASQAMLYGTGMNDADMHKPQIGIGSVWYEGNTCNMHLNQLAQFVKDSVEKENLKGMRFNTIGVSDGISMGTDDMSYSLQSRDLIADSIETVMSAHWYDGLVSIPGCDKNMPGCMMALGRLNRPGFVIYGGTIQAGVMRGKPIDIVTAFQSYGACLSGQITEQERQETIKKACPGAGACGGMYTANTMACAIEALGMSLPFSSSTPATSVEKVQECDKAGETIKNLLELDIKPRDIMTRKAFENAMVLITVMGGSTNAVLHLLAMASSVDVDLSIDDFQEIANKTPVLADFKPSGKYVMANLHAIGGTPAVMKMLLKAGMLHGDCLTVTGKTLAENLENVADLPEDNTIIHKLDNPIKKTGHLQILKGNVAPEGSVAKITGKEGEIFEGVANVFDSEEEMVAAVETGKVKKGDVIVIRYEGPKGGPGMPEMLKPTSLIMGAGLGQDVALITDGRFSGGSHGFIVGHITPEAYEGGMIALLENGDKITIDAINNVINVDLSDQEIAQRKSKWRASKQKASRGTLKKYIKTVSSASKGCVTDLD GT:EXON 1|1-560:0| SW:ID ILVD_FRATM SW:DE RecName: Full=Dihydroxy-acid dehydratase; Short=DAD; EC=4.2.1.9; SW:GN Name=ilvD; OrderedLocusNames=FTM_1218; SW:KW 4Fe-4S; Amino-acid biosynthesis;Branched-chain amino acid biosynthesis; Complete proteome; Iron;Iron-sulfur; Lyase; Metal-binding. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->560|ILVD_FRATM|0.0|100.0|560/560| GO:SWS:NREP 6 GO:SWS GO:0051539|"GO:4 iron, 4 sulfur cluster binding"|4Fe-4S| GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0009082|"GO:branched chain family amino acid biosynthetic process"|Branched-chain amino acid biosynthesis| GO:SWS GO:0051536|"GO:iron-sulfur cluster binding"|Iron-sulfur| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| PROS 125->135|PS00886|ILVD_EDD_1|PDOC00690| PROS 466->477|PS00887|ILVD_EDD_2|PDOC00690| SEG 190->199|acpgagacgg| SEG 438->452|egpkggpgmpemlkp| BL:PDB:NREP 1 BL:PDB:REP 84->525|2gp4A|2e-24|30.3|393/509| RP:PDB:NREP 2 RP:PDB:REP 34->292|2cwlB|4e-33|12.0|234/298| RP:PDB:REP 339->525|3ejfA|8e-27|10.7|159/166| RP:PFM:NREP 1 RP:PFM:REP 37->554|PF00920|e-141|49.2|518/521|ILVD_EDD| HM:PFM:NREP 1 HM:PFM:REP 37->555|PF00920|2.5e-217|53.9|519/521|ILVD_EDD| GO:PFM:NREP 2 GO:PFM GO:0003824|"GO:catalytic activity"|PF00920|IPR000581| GO:PFM GO:0008152|"GO:metabolic process"|PF00920|IPR000581| RP:SCP:NREP 2 RP:SCP:REP 51->379|2gp4A2|9e-82|29.1|285/332|d.334.1.1| RP:SCP:REP 381->559|2gp4A1|4e-32|28.5|179/190|c.8.2.2| HM:SCP:REP 5->379|2gp4A2|1.1e-134|49.9|369/0|d.334.1.1|1/1|IlvD/EDD N-terminal domain-like| HM:SCP:REP 380->559|2gp4A1|3.7e-57|53.1|177/0|c.8.2.2|1/1|LeuD/IlvD-like| OP:NHOMO 1760 OP:NHOMOORG 913 OP:PATTERN 11-1--1111111111-11111111--11211111111111111111111211111-----1--1-11 2131211211111121111-121114111111211133332113242-211123111111121-23423211111111-11-111111111112---11--211211212---------------11111111111111111111111111111111111111111121111111111111111111111-11111111111111111121111111111111--1111111211111111111111111112---------------------1-111-------11111111111111-------------111222111-14-23111111111121112---2-1--1211122111111111111--12135444-22-2526771134543333333333225-33433537851-5554536666775522233423444342122222251122111-----------------------------2226222552746656452222557A222223447664512552325336463982211222212232222111311-2212111111111-1111111111111-3111111111112111111111111111222243323-2322322322233332222322-1-121111111122212314222422222-2232222222233223222222211123232323333323222322222221-22222222222211-------111122246111111-111111114444423111422222223322224333311-1-11-1121312222222123222222222222221111111111--------------------------------------1--1-111131 ------1-------134224464575622222222222222222222234334434333222111111111111111-1121111111-23242222222112222--3----------------------------------------------------------------1-1111I1111111342121133332 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 535 STR:RPRED 95.5 SQ:SECSTR #######################ccccccccccccccccccccccHHHHccccHHHHHHHGGGTTcTTcHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHcccTTcccHHcccccGGGcTTGGGGcccccHHHHTcccccccccTTcccccGGGccccccHHHHHHHHHHHHHHHHHHHHHHHTTcccHHHHHHHHHHHHHHHHHHTTcHHHHHHHHHHHHHHHHHHHHHHcccGGGGcccccccGGGcHHHHTTTEEHHHHTTTTcEEEEccccccTTGGHHHHHHHHHHHHHHHcHHHHHHHHHHHHHTcGGHHHHHHHHHHHTccccEEEGcHHHHHHHHHHHTTccccccccccccccTccccccHHTcccccHHHHHHHHHHcHHTTHHHHHHHHHHHHHccccEEEEccccTTEEEEEEEccccTTcccHHHHHHHHHHHHHHHHHTTccTTccEEEEEcccTTcTTccHHHHHHHHHHHHTTcccEHHHHHHHcEEEEEccHHHHHHTcHHHHHHHHHHHHHHHHHHHHHHTTcGGGTTc## PSIPRED ccccHHHHHHHHcccccHHHHHHHHHHccccHHHHcccEEEEEEcccccccccccHHHHHHHHHHHHHHcccEEEEcccccHHHcccccHHHHHHHHHHHHHHHHHHHHHHHcccccEEEEEccccccHHHHHHHHHHccccEEEEEcccccccccccEEcccHHHHHHHHHHHcccccHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHHHHHHccccHHHHccHHHHHHHHHHHHHHcccHHHHHHHHHHHHHccccccHHHHHHHHccccEEEEEccccHHHHHHHHHcccHHHHHHHHHHcccccccccccccccHHHHHHccccccccccEEccHHHHccccccEEEEEcccccccEEEEEEcccccEEEEEEEEEccHHHHHHHHHccccccccEEEEcccccccccccHHHHHccHHHHHccccccccEEEcccccccccccccccccHHHHccccEEEEEcccEEEEEccccEEEEEccHHHHHHHHHHccccccccccHHHHHHHHHcccHHHccEEccc //