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Francisella tularensis subsp. mediasiatica FSC147 (ftul2)
Gene : metK
DDBJ      :metK         S-adenosylmethionine synthetase
Swiss-Prot:METK_FRATO   RecName: Full=S-adenosylmethionine synthetase;         EC=2.5.1.6;AltName: Full=Methionine adenosyltransferase;AltName: Full=AdoMet synthetase;AltName: Full=MAT;

Homologs  Archaea  2/68 : Bacteria  874/915 : Eukaryota  191/199 : Viruses  0/175   --->[See Alignment]
d.130.1
:386 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   5->384 1p7lA PDBj e-142 65.1 %
:RPS:PDB   65->303 1dxjA PDBj 2e-57 10.6 %
:RPS:SCOP  4->104 1fugA1  d.130.1.1 * 1e-45 70.3 %
:RPS:SCOP  106->232 1fugA2  d.130.1.1 * 8e-53 59.8 %
:RPS:SCOP  234->386 1fugA3  d.130.1.1 * 2e-71 65.6 %
:HMM:SCOP  3->104 1mxaA1 d.130.1.1 * 1e-44 67.6 %
:HMM:SCOP  110->233 1mxaA2 d.130.1.1 * 3.2e-47 60.5 %
:HMM:SCOP  234->379 1qm4A3 d.130.1.1 * 1e-77 73.8 %
:RPS:PFM   4->101 PF00438 * S-AdoMet_synt_N 7e-38 72.4 %
:RPS:PFM   114->232 PF02772 * S-AdoMet_synt_M 1e-41 58.0 %
:RPS:PFM   234->373 PF02773 * S-AdoMet_synt_C 1e-54 70.3 %
:HMM:PFM   234->373 PF02773 * S-AdoMet_synt_C 1.8e-71 66.7 138/138  
:HMM:PFM   115->232 PF02772 * S-AdoMet_synt_M 2.6e-51 58.5 118/120  
:HMM:PFM   3->101 PF00438 * S-AdoMet_synt_N 1.2e-44 66.7 99/100  
:BLT:SWISS 1->386 METK_FRATO 0.0 100.0 %
:PROS 117->127|PS00376|ADOMET_SYNTHETASE_1
:PROS 260->268|PS00377|ADOMET_SYNTHETASE_2
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ACD30294.1 GT:GENE metK GT:PRODUCT S-adenosylmethionine synthetase GT:DATABASE GIB00719CH01 GT:ORG ftul2 GB:ACCESSION GIB00719CH01 GB:LOCATION complement(238774..239934) GB:FROM 238774 GB:TO 239934 GB:DIRECTION - GB:GENE metK GB:PRODUCT S-adenosylmethionine synthetase GB:PROTEIN_ID ACD30294.1 GB:DB_XREF GI:187711997 GB:GENE:GENE metK LENGTH 386 SQ:AASEQ MSKNYLFTSESVSEGHPDKLADQISDAILDEILKQDKNARVACETLVKTGMALVAGEITTSAWVDIEELVRNVITETGYDNASKGIDGRTCSVINAIGKQSRDIAQGVDRGSLEDLGAGDQGLMFGFATNETPTLMPSAIYYSHLLMRKQAELRKSGKLAWLRPDAKAQVTLAYENDKPKFIDTIVLSTQHNESISQKELHDAVIEEIVKKVIPNELITKDTKYHINPTGVFLIGGPQGDCGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSGAYMGRYIAKNIVAAGLADKCEVQVAYAIGVAKPVSLMVNTFGTGKITDNQIEKLVAEVFDLRVGKIIENLDLLRPIYRKTSNYGHFGRELPEFTWEKIDKADILKSAARI GT:EXON 1|1-386:0| SW:ID METK_FRATO SW:DE RecName: Full=S-adenosylmethionine synthetase; EC=2.5.1.6;AltName: Full=Methionine adenosyltransferase;AltName: Full=AdoMet synthetase;AltName: Full=MAT; SW:GN Name=metK; OrderedLocusNames=FTH_1678; SW:KW ATP-binding; Cobalt; Complete proteome; Cytoplasm; Magnesium;Metal-binding; Nucleotide-binding; One-carbon metabolism; Potassium;Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->386|METK_FRATO|0.0|100.0|386/386| GO:SWS:NREP 6 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006730|"GO:one-carbon metabolic process"|One-carbon metabolism| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 117->127|PS00376|ADOMET_SYNTHETASE_1|PDOC00369| PROS 260->268|PS00377|ADOMET_SYNTHETASE_2|PDOC00369| SEG 254->263|ggaahhggga| BL:PDB:NREP 1 BL:PDB:REP 5->384|1p7lA|e-142|65.1|378/383| RP:PDB:NREP 1 RP:PDB:REP 65->303|1dxjA|2e-57|10.6|226/242| RP:PFM:NREP 3 RP:PFM:REP 4->101|PF00438|7e-38|72.4|98/100|S-AdoMet_synt_N| RP:PFM:REP 114->232|PF02772|1e-41|58.0|119/120|S-AdoMet_synt_M| RP:PFM:REP 234->373|PF02773|1e-54|70.3|138/138|S-AdoMet_synt_C| HM:PFM:NREP 3 HM:PFM:REP 234->373|PF02773|1.8e-71|66.7|138/138|S-AdoMet_synt_C| HM:PFM:REP 115->232|PF02772|2.6e-51|58.5|118/120|S-AdoMet_synt_M| HM:PFM:REP 3->101|PF00438|1.2e-44|66.7|99/100|S-AdoMet_synt_N| GO:PFM:NREP 9 GO:PFM GO:0004478|"GO:methionine adenosyltransferase activity"|PF00438|IPR002133| GO:PFM GO:0005524|"GO:ATP binding"|PF00438|IPR002133| GO:PFM GO:0006730|"GO:one-carbon metabolic process"|PF00438|IPR002133| GO:PFM GO:0004478|"GO:methionine adenosyltransferase activity"|PF02772|IPR002133| GO:PFM GO:0005524|"GO:ATP binding"|PF02772|IPR002133| GO:PFM GO:0006730|"GO:one-carbon metabolic process"|PF02772|IPR002133| GO:PFM GO:0004478|"GO:methionine adenosyltransferase activity"|PF02773|IPR002133| GO:PFM GO:0005524|"GO:ATP binding"|PF02773|IPR002133| GO:PFM GO:0006730|"GO:one-carbon metabolic process"|PF02773|IPR002133| RP:SCP:NREP 3 RP:SCP:REP 4->104|1fugA1|1e-45|70.3|101/102|d.130.1.1| RP:SCP:REP 106->232|1fugA2|8e-53|59.8|127/129|d.130.1.1| RP:SCP:REP 234->386|1fugA3|2e-71|65.6|151/152|d.130.1.1| HM:SCP:REP 3->104|1mxaA1|1e-44|67.6|102/102|d.130.1.1|1/1|S-adenosylmethionine synthetase| HM:SCP:REP 110->233|1mxaA2|3.2e-47|60.5|124/124|d.130.1.1|1/1|S-adenosylmethionine synthetase| HM:SCP:REP 234->379|1qm4A3|1e-77|73.8|141/144|d.130.1.1|1/1|S-adenosylmethionine synthetase| OP:NHOMO 1349 OP:NHOMOORG 1067 OP:PATTERN ------------------------------------------------------------------11 1221111111211111111-1111111111111111111112211111111111111111111222211111111111111111111111111111---11111111111---------------111111111112112211211111122111111111111111221111111111111111111--1111111111211111111111111111111111111111111111111111111111111111111111111111111111111111112111111121111111111111112111111111111111111121121111111121213311111111111111112111121121111111111111111111-1111111211111111111111-11111111121111111111111111111111111111111111111111111121121111111---1----2---211111111111111111111111111111111111111111111111111111111111111111111111111111112111131111111111111221111111111111111111111111111111111121122111111111111111111111111111111111-111221--11111111111112111211-111111211112111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112---11-11111111111111111111111111111111 1111111-429111111111111212111111111111111-11111-1111111111111111111111221111222211111111-11111111111111112-12337C55581242222322328I2-32412123212122221213322322-3911232A21368411111N211115358154-231116 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 384 STR:RPRED 99.5 SQ:SECSTR cccEEEEEEEEEEEccEEEEcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHTccHHHHcGGGEEcGGGTcHHHHHHHTTTTTcTTccccccccHHHHHHHHTTcTHTTTTcccHHHHHHHHHHHHHHHHHHTccccTTcGGcTTccccccccccccccTTccccTTccTcccHHHHHHHHHHHHHTccTTTcTTHHHHcHHHHHHHHHHcccTTcccHHHHHTTcccccHHHHHTTccccHHHHHHHHHHHTTTTccccccHHccccccHHHHHHHHHHHHHHHHHTcccccccccTTcccccTTcccccEEEEEcTTcccccHHHHHHHHHHHccccHHHHHHHHTccccccGGGGcccccccTcTTcTTTcccHHHHHHHTc## DISOP:02AL 386-387| PSIPRED ccccEEEEccccccccHHHHHHHHHHHHHHHHHHHccccEEEEEEEEEccEEEEEEEEEcccEEEHHHHHHHHHHHcccccHHcccccccEEEEEcccccccHHHcccccccHHHccccccEEEEEEEcccccccccHHHHHHHHHHHHHHHHHHcccccccccccEEEEEEEEEccEEEEEEEEEEEEEccccccHHHHHHHHHHHHHHHHccHHHcccccEEEEcccccEEcccccccccccccEEEEEccccccccccccccccccccHHHHHHHHHHHHHHHHHHccccEEEEEEEEEEcccccccEEEEEEcccccccHHHHHHHHHHHccccHHHHHHHccccccccccccccccccccccccccccHHHHHHHHHHHcc //