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Francisella tularensis subsp. mediasiatica FSC147 (ftul2)
Gene : pnp
DDBJ      :pnp          polyribonucleotide nucleotidyltransferase
Swiss-Prot:PNP_FRATM    RecName: Full=Polyribonucleotide nucleotidyltransferase;         EC=2.7.7.8;AltName: Full=Polynucleotide phosphorylase;         Short=PNPase;

Homologs  Archaea  34/68 : Bacteria  862/915 : Eukaryota  83/199 : Viruses  0/175   --->[See Alignment]
a.4.9b.40.4d.101.1d.14.1d.26.2d.51.1
:693 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   8->544 3h1cG PDBj e-148 50.7 %
:BLT:PDB   532->607 2annA PDBj 9e-04 30.7 %
:BLT:PDB   625->690 1sroA PDBj 4e-08 37.9 %
:RPS:PDB   8->576 1e3hA PDBj e-163 40.7 %
:RPS:PDB   557->690 2e3uA PDBj 5e-09 16.8 %
:RPS:SCOP  13->86 1e44A  d.26.2.1 * 5e-16 7.5 %
:RPS:SCOP  148->235 1e3hA5  d.101.1.1 * 5e-21 23.9 %
:RPS:SCOP  241->321 1e3hA1  a.4.9.1 * 3e-20 33.8 %
:RPS:SCOP  298->473 2nn6E1  d.14.1.4 * 3e-42 18.5 %
:RPS:SCOP  459->572 2nn6A2  d.101.1.1 * 2e-28 12.6 %
:RPS:SCOP  548->597 2ctkA1  d.51.1.1 * 3e-08 16.0 %
:RPS:SCOP  625->690 1sroA  b.40.4.5 * 2e-10 37.9 %
:HMM:SCOP  1->143 1e3hA2 d.14.1.4 * 2e-52 53.1 %
:HMM:SCOP  144->237 1e3hA5 d.101.1.1 * 1.6e-28 44.7 %
:HMM:SCOP  225->328 1whuA_ a.4.9.1 * 1.1e-22 37.6 %
:HMM:SCOP  316->467 1oysA1 d.14.1.4 * 2.2e-39 35.6 %
:HMM:SCOP  456->563 1udsA2 d.101.1.1 * 4.3e-30 37.5 %
:HMM:SCOP  543->639 1we8A_ d.51.1.1 * 1.3e-20 31.2 %
:HMM:SCOP  611->692 1q46A2 b.40.4.5 * 3.2e-13 32.9 %
:RPS:PFM   241->321 PF03726 * PNPase 3e-12 42.0 %
:RPS:PFM   327->459 PF01138 * RNase_PH 5e-16 35.2 %
:RPS:PFM   462->530 PF03725 * RNase_PH_C 2e-05 51.6 %
:RPS:PFM   625->691 PF00575 * S1 6e-05 34.3 %
:HMM:PFM   13->143 PF01138 * RNase_PH 2.1e-25 36.6 123/132  
:HMM:PFM   326->459 PF01138 * RNase_PH 1.6e-19 26.4 129/132  
:HMM:PFM   147->209 PF03725 * RNase_PH_C 3.4e-17 41.3 63/68  
:HMM:PFM   463->530 PF03725 * RNase_PH_C 2.1e-12 38.1 63/68  
:HMM:PFM   241->321 PF03726 * PNPase 2e-23 38.3 81/83  
:HMM:PFM   560->615 PF00013 * KH_1 1.2e-11 31.5 54/57  
:HMM:PFM   622->689 PF00575 * S1 1.6e-10 32.4 68/74  
:BLT:SWISS 1->693 PNP_FRATM 0.0 100.0 %
:PROS 633->643|PS00136|SUBTILASE_ASP
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ACD31221.1 GT:GENE pnp GT:PRODUCT polyribonucleotide nucleotidyltransferase GT:DATABASE GIB00719CH01 GT:ORG ftul2 GB:ACCESSION GIB00719CH01 GB:LOCATION complement(1487575..1489656) GB:FROM 1487575 GB:TO 1489656 GB:DIRECTION - GB:GENE pnp GB:PRODUCT polyribonucleotide nucleotidyltransferase GB:PROTEIN_ID ACD31221.1 GB:DB_XREF GI:187712924 GB:GENE:GENE pnp LENGTH 693 SQ:AASEQ MKIFREVFELGNKEIILETGGMARQADGSVTVSCGNNIVLVTTVVKKSVADGTDFFPLSVHYLEKTYAAGKIPGGFLRREGRPSEEQILISRLIDRSIRPSFPDGFFNEIQIVATVLSYDGAFSPDILALIGASASLAISGAPYDDVVAGVRVGYTNGKYILNPNKQDLRDSDLDLVVSGTDDAILMVESEANSLPESVMLGGILYAHKHLKTIINSINRLAKVASKPRMEYSIYQINKFLKSQIKSQFFGEIKNAYTIASKQERNLKLNAIRKNVLEYIFSSDVDGNEYTEKEILEAFHDIEKDLVRSNILEGKPRIDGRCTETIRPINVKIGVLPGVHGSALFTRGETQALVVTTLGSDRDAQLVESLDGIEKCRYMLHYNFPPYSVGECGMVGMAPKRREIGHANLAKRATQAVFPNEEAYPYVVRVVSEILESNGSSSMATVCGSSLSMMDAGVPIAEPVAGIAMGLIKDGAKYAVLSDILGDEDHLGDMDFKVAGTRYGVTALQMDIKIKGISREILEQALEQARVGRLHILGIMNEVIKEHKEAVSDVAPQIHVMNINPAKIKDVVGRGGATVKGIVEKTGAQIDTSDSGEVKVFAKDKKSMDMAVAMIEEIVAEVEEGQVYKGKIVKLLDSGVFVNLLGSQDGYLPFSEIEQAGMKTNSLVEGQGLEVLVQNIDRGGRVKLSLVAR GT:EXON 1|1-693:0| SW:ID PNP_FRATM SW:DE RecName: Full=Polyribonucleotide nucleotidyltransferase; EC=2.7.7.8;AltName: Full=Polynucleotide phosphorylase; Short=PNPase; SW:GN Name=pnp; OrderedLocusNames=FTM_1385; SW:KW Complete proteome; Cytoplasm; Nucleotidyltransferase; RNA-binding;Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->693|PNP_FRATM|0.0|100.0|693/693| GO:SWS:NREP 4 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016779|"GO:nucleotidyltransferase activity"|Nucleotidyltransferase| GO:SWS GO:0003723|"GO:RNA binding"|RNA-binding| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 633->643|PS00136|SUBTILASE_ASP|PDOC00125| SEG 88->99|ilisrlidrsir| SEG 127->142|ilaligasaslaisga| SEG 168->179|dlrdsdldlvvs| SEG 610->624|mavamieeivaevee| BL:PDB:NREP 3 BL:PDB:REP 8->544|3h1cG|e-148|50.7|533/543| BL:PDB:REP 532->607|2annA|9e-04|30.7|75/148| BL:PDB:REP 625->690|1sroA|4e-08|37.9|66/76| RP:PDB:NREP 2 RP:PDB:REP 8->576|1e3hA|e-163|40.7|551/585| RP:PDB:REP 557->690|2e3uA|5e-09|16.8|131/166| RP:PFM:NREP 4 RP:PFM:REP 241->321|PF03726|3e-12|42.0|81/83|PNPase| RP:PFM:REP 327->459|PF01138|5e-16|35.2|128/130|RNase_PH| RP:PFM:REP 462->530|PF03725|2e-05|51.6|64/68|RNase_PH_C| RP:PFM:REP 625->691|PF00575|6e-05|34.3|67/74|S1| HM:PFM:NREP 7 HM:PFM:REP 13->143|PF01138|2.1e-25|36.6|123/132|RNase_PH| HM:PFM:REP 326->459|PF01138|1.6e-19|26.4|129/132|RNase_PH| HM:PFM:REP 147->209|PF03725|3.4e-17|41.3|63/68|RNase_PH_C| HM:PFM:REP 463->530|PF03725|2.1e-12|38.1|63/68|RNase_PH_C| HM:PFM:REP 241->321|PF03726|2e-23|38.3|81/83|PNPase| HM:PFM:REP 560->615|PF00013|1.2e-11|31.5|54/57|KH_1| HM:PFM:REP 622->689|PF00575|1.6e-10|32.4|68/74|S1| GO:PFM:NREP 10 GO:PFM GO:0000175|"GO:3'-5'-exoribonuclease activity"|PF03726|IPR015848| GO:PFM GO:0003723|"GO:RNA binding"|PF03726|IPR015848| GO:PFM GO:0006396|"GO:RNA processing"|PF03726|IPR015848| GO:PFM GO:0000175|"GO:3'-5'-exoribonuclease activity"|PF01138|IPR001247| GO:PFM GO:0003723|"GO:RNA binding"|PF01138|IPR001247| GO:PFM GO:0006396|"GO:RNA processing"|PF01138|IPR001247| GO:PFM GO:0000175|"GO:3'-5'-exoribonuclease activity"|PF03725|IPR015847| GO:PFM GO:0003723|"GO:RNA binding"|PF03725|IPR015847| GO:PFM GO:0006396|"GO:RNA processing"|PF03725|IPR015847| GO:PFM GO:0003723|"GO:RNA binding"|PF00575|IPR003029| RP:SCP:NREP 7 RP:SCP:REP 13->86|1e44A|5e-16|7.5|67/84|d.26.2.1| RP:SCP:REP 148->235|1e3hA5|5e-21|23.9|88/111|d.101.1.1| RP:SCP:REP 241->321|1e3hA1|3e-20|33.8|77/83|a.4.9.1| RP:SCP:REP 298->473|2nn6E1|3e-42|18.5|168/181|d.14.1.4| RP:SCP:REP 459->572|2nn6A2|2e-28|12.6|111/118|d.101.1.1| RP:SCP:REP 548->597|2ctkA1|3e-08|16.0|50/91|d.51.1.1| RP:SCP:REP 625->690|1sroA|2e-10|37.9|66/76|b.40.4.5| HM:SCP:REP 1->143|1e3hA2|2e-52|53.1|143/149|d.14.1.4|1/2|Ribosomal protein S5 domain 2-like| HM:SCP:REP 144->237|1e3hA5|1.6e-28|44.7|94/111|d.101.1.1|1/2|Ribonuclease PH domain 2-like| HM:SCP:REP 225->328|1whuA_|1.1e-22|37.6|101/0|a.4.9.1|1/1|Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3| HM:SCP:REP 316->467|1oysA1|2.2e-39|35.6|146/151|d.14.1.4|2/2|Ribosomal protein S5 domain 2-like| HM:SCP:REP 456->563|1udsA2|4.3e-30|37.5|104/105|d.101.1.1|2/2|Ribonuclease PH domain 2-like| HM:SCP:REP 543->639|1we8A_|1.3e-20|31.2|96/0|d.51.1.1|1/1|Eukaryotic type KH-domain (KH-domain type I)| HM:SCP:REP 611->692|1q46A2|3.2e-13|32.9|82/0|b.40.4.5|1/1|Nucleic acid-binding proteins| OP:NHOMO 1047 OP:NHOMOORG 979 OP:PATTERN 111----11111111111-----1--------111-------------11-1111111111111---1 1111111111111111111-111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111----------------------11111111111111111111111-1111111111111111111111114111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111-1111111111111111111111111111-1111111111111111111111111111111--1---111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111---------------------1111111111111 -----11-------------------------------------------------------------------------------1---------------------1121111-1111111112121791-13111-111111111112-11-1111---12-12311231212-12J222111113-322221111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 693 STR:RPRED 100.0 SQ:SECSTR cccEEEEGGGcEEEEEEEEccccTTccEEEEEEETTTEEEEEEEEcccccTTcccccEEEEEEEEcGGGTcccccTTcccccccHHHHHHHHHHHHHHHHHccTTccccEEEEEEEEEccTTcccHHHHHHHHHHHHHHTTcccccccEEEEEEEETTEEEEcccHHHHTTEEEEEEEEEcTTHHHHHHTTcccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccHHHHHHHHHHHHHHHHHHTTcccHHHHHHHHHHHHHHHHHHTTTTcHHccTTcHHHHHHHHHHHHHHHHHHHHHHTcccTTcccTTccccEEEEEcccccccEEEEEEETTEEEEEEEEEEGGcGcEEccccccccEEcEEEEEEccGGGGTccccccccccHHHHHHHHHHHHHHGGGcccTTTccEEEEEEEEEEEccccHHHHHHHHHHHHHHHHTcccccccEEEEEEEEEEEEEEEEEcccccHHHHHccEEEEEEEccccEEEEEEEEccccccHHHHHHHHHHHHHHHHHHHHHHHHHcHcccccccTTccccccHHHHccccccccccccccHHccGGGTccccccHHHHHHHHHHHHcTTccHHHHHTcccGGGccTHHHHccccEEEcccccEEcccccccccccccGGcccccccHHcccccccccccccccccccEEEEccTc DISOP:02AL 693-694| PSIPRED cccEEEEEEEccEEEEEEEEEEEEccccEEEEEEcccEEEEEEEEcccccccccccEEEEEEEcccccccccccccEEccccccccEEEEEEEccccccccccccccccEEEEEEEEEEcccccHHHHHHHHHHHHHHHccccccccEEEEEEEEEccEEEEcccHHHHHHccccEEEEEccccEEEEEEccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccHHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHcccccccccHHHHHHHHHHHHHHHHHHHHHcccccccccccccEEEEEEEEcccccccEEEEEEEcccEEEEEEEcccccccccccccccccEEEEEEEEEEccccccccccccccccHHHHHHHHHHHHHHHHHccHHHcccEEEEEEEEEEEccccHHHHHHHHHHHHHHHccccccccccEEEEEEEEcccccEEEEcccHHHHHHcccEEEEEEccccEEEEEEEcccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccEEEEEEcHHHHHHHccccHHHHHHHHHHHcccEEEccccEEEEEEEcHHHHHHHHHHHHHHHcccccccEEEEEEEEEEccEEEEEEccccEEEEEEEEcccccccccEEEcccEEEEEEEEEcccccEEEEEccc //