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Francisella tularensis subsp. mediasiatica FSC147 (ftul2)
Gene : putA
DDBJ      :putA         bifunctional proline dehydrogenase, pyrroline-5-carboxylate dehydrogenase
Swiss-Prot:             

Homologs  Archaea  56/68 : Bacteria  794/915 : Eukaryota  190/199 : Viruses  0/175   --->[See Alignment]
a.176.1c.1.23c.82.1
:1354 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   28->521 1k87A PDBj e-143 55.3 %
:BLT:PDB   575->1021 1uzbA PDBj 2e-59 32.4 %
:BLT:PDB   1100->1289 2iluA PDBj 2e-11 27.2 %
:RPS:PDB   154->475 2ekgB PDBj 7e-79 30.9 %
:RPS:PDB   571->1028 2bhpA PDBj 6e-90 34.2 %
:RPS:PDB   1060->1311 3ed6A PDBj 4e-26 20.2 %
:RPS:SCOP  20->181 1k87A1  a.176.1.1 * 3e-49 39.1 %
:RPS:SCOP  183->521 1k87A2  c.1.23.2 * e-128 59.9 %
:RPS:SCOP  571->1028 1uzbA  c.82.1.1 * 2e-92 34.7 %
:RPS:SCOP  1060->1297 1euhA  c.82.1.1 * 9e-26 18.9 %
:HMM:SCOP  12->182 1k87A1 a.176.1.1 * 5.8e-59 47.4 %
:HMM:SCOP  183->528 1k87A2 c.1.23.2 * 1.5e-127 47.1 %
:HMM:SCOP  571->1033 1uzbA_ c.82.1.1 * 4.7e-127 38.5 %
:HMM:SCOP  1073->1311 1uzbA_ c.82.1.1 * 1.6e-36 26.8 %
:RPS:PFM   169->486 PF01619 * Pro_dh 4e-76 51.9 %
:RPS:PFM   579->1016 PF00171 * Aldedh 1e-70 39.7 %
:RPS:PFM   1080->1292 PF00171 * Aldedh 3e-17 27.2 %
:HMM:PFM   573->1027 PF00171 * Aldedh 5.4e-122 38.6 446/462  
:HMM:PFM   1071->1307 PF00171 * Aldedh 1.2e-37 28.0 232/462  
:HMM:PFM   154->489 PF01619 * Pro_dh 1.7e-109 40.8 331/345  
:BLT:SWISS 20->1024,1178->1352 PUTA_SALTY 0.0 51.8 %
:BLT:SWISS 1078->1160 LPHN2_MOUSE 3e-05 28.4 %
:PROS 830->841|PS00070|ALDEHYDE_DEHYDR_CYS
:REPEAT 2|351->808|854->1311

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ACD30792.1 GT:GENE putA GT:PRODUCT bifunctional proline dehydrogenase, pyrroline-5-carboxylate dehydrogenase GT:DATABASE GIB00719CH01 GT:ORG ftul2 GB:ACCESSION GIB00719CH01 GB:LOCATION 909164..913228 GB:FROM 909164 GB:TO 913228 GB:DIRECTION + GB:GENE putA GB:PRODUCT bifunctional proline dehydrogenase, pyrroline-5-carboxylate dehydrogenase GB:PROTEIN_ID ACD30792.1 GB:DB_XREF GI:187712495 GB:GENE:GENE putA LENGTH 1354 SQ:AASEQ MNDLLNHSGEYPISKEIMNISKYWLIDEKEAMTKLVEKAHMSSVQKAQVRERAYGLVEKVRKNRLKKSGIDAFMIEYDLSSEEGIVLMCLAEALLRVPDKYTIDLLIKDKLTSAAWKNHVGMEKHLFVNAATWSLMLTGKILKDPHRSYRKVFQNFLKKTSEPVIRQAMKQAMKIVSKQYVLGETIEEALKVSEAKVARGYSYSYDMLGEAAMTMDDAEYYYSQYLHAIHELAKYATNTEIKKNPGISIKLSALHPRYEVAKHQRVHTELYPKLLKLTQLAKDYNVGMNIDAEETERLQISLELVERLAHEPSLEGFNGIGIVVQAYQKRAPYVLDYLANLAKKTNRRFMIRLVKGAYWDAEIKHAQEQGLAGYPVFTRKYHTDVSYQACVKQLFENHQYIYPQFATHNAQTVAVVFELANGNRDFEFQCLHGMGDALYDNVVGKEGYEDIPCRIYAPVGGHKHLLAYLVRRLLENGANSSFVNRIVDENLPIEELIEDPVKKAIDHGCGQHPNIPYPKDIVSPRLNSQGHNTNDFAVLADMYKQIEKYTHKNTYKAKPIVSGIDLDKTITESVINPNTNEVIGSVINADAKIAKRALKNAQSAFEEWSNTPATKRADILEKFADLLEQDTNKFIAIAMIEAGKTLANAIDEVREAVDFCRYYAAQARKEFNGPIELPALSDHLKQIEFTGRGAMVCISPWNFPLAIFLGQITAVLAAGNTVVAKPAEQTPIIAYKAVKLLFKAGLPKNVLQFTPGDGATVGSALVKSPVCKGVIFTGSTEVAAIINQTLANKSSEIVPFIAETGGQNAMIVDSSSLPEQVTADVIHSAFDSAGQRCSALRILCLQEDIADNYIKMIVGAMKELKIGDSKYIDTDVGPVIDKEAADNLNAYIEEKKSQFKLIYQAQPNQDTQKGTFVMPTAFEIDKISDLGREQFGPILHILRFKANQLDKLINDINATGYGLTAGVHSRINEVMNYVKNNLKAGNIYVNRNIVGAVVGVQPFGGQGKSGTGPKAGGPYYMHRLANEKLSGVGAVEEIYNPEKIAEDEKQTNKLIKDKYTITNIVAGEKAKKDKYTNLKAANGKTIGKKYVASVNTVDNAIEIASKEVEIWNHVNAEQRAATIEKFLELLEKERHLIASSLVVESNISVEDAHIQIDKTIQQVAYYCLQAKKEFAHPQLLPGPTGEIDELSLKGRGVVVSMCSSSDLLIRFVGQTAAALLAGNTVVAKPAYTGNLTAYNIVKLMLKAGIDSKVLHLVLSDDEEITSALLFNSKVALVAFSGSVSAVKQVHQALVLRRGAIIPFVAESVAKNGKCTSLAIETASPLYLRRFVVEKTVSVDTTASGGNASLMSLEE GT:EXON 1|1-1354:0| BL:SWS:NREP 2 BL:SWS:REP 20->1024,1178->1352|PUTA_SALTY|0.0|51.8|1135/1320| BL:SWS:REP 1078->1160|LPHN2_MOUSE|3e-05|28.4|81/891| PROS 830->841|PS00070|ALDEHYDE_DEHYDR_CYS|PDOC00068| NREPEAT 1 REPEAT 2|351->808|854->1311| BL:PDB:NREP 3 BL:PDB:REP 28->521|1k87A|e-143|55.3|483/514| BL:PDB:REP 575->1021|1uzbA|2e-59|32.4|442/516| BL:PDB:REP 1100->1289|2iluA|2e-11|27.2|188/476| RP:PDB:NREP 3 RP:PDB:REP 154->475|2ekgB|7e-79|30.9|278/298| RP:PDB:REP 571->1028|2bhpA|6e-90|34.2|453/516| RP:PDB:REP 1060->1311|3ed6A|4e-26|20.2|248/502| RP:PFM:NREP 3 RP:PFM:REP 169->486|PF01619|4e-76|51.9|310/329|Pro_dh| RP:PFM:REP 579->1016|PF00171|1e-70|39.7|426/440|Aldedh| RP:PFM:REP 1080->1292|PF00171|3e-17|27.2|211/440|Aldedh| HM:PFM:NREP 3 HM:PFM:REP 573->1027|PF00171|5.4e-122|38.6|446/462|Aldedh| HM:PFM:REP 1071->1307|PF00171|1.2e-37|28.0|232/462|Aldedh| HM:PFM:REP 154->489|PF01619|1.7e-109|40.8|331/345|Pro_dh| GO:PFM:NREP 10 GO:PFM GO:0004657|"GO:proline dehydrogenase activity"|PF01619|IPR002872| GO:PFM GO:0006537|"GO:glutamate biosynthetic process"|PF01619|IPR002872| GO:PFM GO:0006562|"GO:proline catabolic process"|PF01619|IPR002872| GO:PFM GO:0055114|"GO:oxidation reduction"|PF01619|IPR002872| GO:PFM GO:0008152|"GO:metabolic process"|PF00171|IPR015590| GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF00171|IPR015590| GO:PFM GO:0055114|"GO:oxidation reduction"|PF00171|IPR015590| GO:PFM GO:0008152|"GO:metabolic process"|PF00171|IPR015590| GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF00171|IPR015590| GO:PFM GO:0055114|"GO:oxidation reduction"|PF00171|IPR015590| RP:SCP:NREP 4 RP:SCP:REP 20->181|1k87A1|3e-49|39.1|151/163|a.176.1.1| RP:SCP:REP 183->521|1k87A2|e-128|59.9|339/351|c.1.23.2| RP:SCP:REP 571->1028|1uzbA|2e-92|34.7|453/516|c.82.1.1| RP:SCP:REP 1060->1297|1euhA|9e-26|18.9|238/474|c.82.1.1| HM:SCP:REP 12->182|1k87A1|5.8e-59|47.4|171/175|a.176.1.1|1/1|N-terminal domain of bifunctional PutA protein| HM:SCP:REP 183->528|1k87A2|1.5e-127|47.1|346/0|c.1.23.2|1/1|FAD-linked oxidoreductase| HM:SCP:REP 571->1033|1uzbA_|4.7e-127|38.5|457/516|c.82.1.1|1/2|ALDH-like| HM:SCP:REP 1073->1311|1uzbA_|1.6e-36|26.8|239/516|c.82.1.1|2/2|ALDH-like| OP:NHOMO 9809 OP:NHOMOORG 1040 OP:PATTERN 221-1-4754454653-312111-B4432-521-11111111211222124431-1--1-13351--1 7AA5L94788C547JPJ9A-9N22Kd99999GSQWSOV**9M6T67781744SIPDA7--DDP3DENMKLB----111-122H11111--12-211---63747494756--------------12211211212266687---6445533431311-11312232455441111-111111177855-1-CAAAAAAA9BBBBAA998FEAA6DACCAIGEFA7222221D64666666666666668778811112311111121122-11122---2221111-2211111111111111-1112111121--111---2-11162223223221-211-2222-12-41---2211---1--1---1119-5HEEA11111B6GBK546AA897FGHHFDHCHGH-45D43J6ANOB-NJJKLLVRNWQQEAAC5BHOCAAC8JJEDEEEEEEADC6475822111111----1111-1111-11-11118APcB2BOKDEcYaaYaQIIIFZZaeNNLLAMuVuMaTL14GCFCADA8GDMCKP333-112A62444444132AC654514331322222-33334254433338A15211322211211111111112-11132971894K7DB9A99998AC777987BA9BD-1-5421------A967587B998B878BC-9CAC988C7B98ABBABB9IJI998A4A98998999A77A797I773667621466687657888--1622112888717DKZ222112-----2223MLMHK8H8DAH1KKJKKPPUHTSPOCKHJ3211132122544B566669B88B8999987555------11441111--------2-2----1---1-12-111-11--111111112-2-2-331 ----CBA-A53-9B8HIKJRNQKRSSREEACCCEEDEFDEDEEBDDCDKUUb*jLLDCDDDCC9B6AA4B88C9A994998AA8AC57-HSDICGCDCA9A9GGCE-9HBTMaGINKB9BAEJDMO6SBp*P-QNRAD97MDDKDAEBE8G77YDFEEMKbWDNDF9SBCGAKJC5774*6555AKDaUKIR88TFMIB ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 1305 STR:RPRED 96.4 SQ:SECSTR ###################HHHHTTccHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHTTTTccHHHHHHHHHHHHHHHTcccHHHHHHHHHHTTTTTH#####ccccTTTTcccHHHHHHccH#####HHHHHHHHHHHHHHHHcHHHHHHHHHHcHHHHHHHcccccHHHHHHHHHHHHHTTcEEEEEEcccccccHHHHHHHHHHHHHHHHHHTTHHTTcHHHHcccccEEEEEGGGGGGGccTTTTcHHHHHHHHHHHHHHGGGTEEEEEccccGGGHHHHHHHHHHHHHcGGGTTcccEEEEEETTcTTHHHHHHHHHHHHHHGGGcccEEEEcccccccTHHHHHHHTcccTTccccHHHHHHHHHHHHHHHHHHTTTccEEEEcccHHHHHHHHHHHHcGGGEEEEEETTccHHHHHHHHcHTTcTcccEEEEEEEccGTTHHHHHHHHHTcHHcTTcHHHHTTcTTccHHHHTccHHHHHHccTTcccTTcccTTcc##cccEEccccGGGccEEEcTTcEEEEEccGGGccccHHHHEEccccEEEEEEEcTcTTcEEEEEEcccHHHHHHHHHHHHHHHHHHTTccHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHGGGGccccccccccTTEEEEEEEEEccEEEEEcccccTTHHHHHHHHHHHHTTcEEEEEccGGGHHHHHHHHHHHHHHTccTTcEEEccccTTTHHHHHHHcTTccEEEEEccHHHHHHHHHHHTcccccccEEEEEccccEEEEEcTTccHHHHHHHHHHHHHGGGGccTTcEEEEEEEHHHHHHHHHHHHHHHTTcccccGGGGcccccccccHHHHHHHHHHHHHHTTTcEEEEccccccccccccccccEEEEcccTTGGTccccccEEEEEEEcEccHHHHHHHHHccccccEEEEEcccHHHHHHHHHHccccEEEEccccccccTTTccccccGGGccccccTcHHHHHTTEEEEEEEEEcccccccccHHHHHHHHHHHHHTcccccEEEEEEccccGGGccEEcccccccccccEEEEEcHHHHHHHHHHHHHHHHTTccHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHGGGGccccccccccTTEEEEEEEEEccEEEEEcccccTTHHHHHHHHHHHHTTcEEEEEccGGGHHHHHHHHHHHHHHTccTTcEEEccccTTTHHHHHHHcTTccEEEEEccHHHHHHHHHHHTcccTTcccccEEEEEccccEEEEEcTTcHHHHHHHHHHHHHG################## PSIPRED cccHHccccccccHHHHHHccccccccHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHcccHHHHHHHHHHHHHHHccccHHHHHHHHHHHHcccHHHHHcccccccHHHHHHHHHHHcccccccccccHHHHHHHHHcccccHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHcccEEEEEcHHHHHccHHHHHHHHHHHHHHHHHHHHHccccccccccEEEEEEccccccccHHcHHHHHHHHHHHHHHHHHHHHHccccEEEEHHHHHHHHHHHHHHHHHHccHHHccccccEEEEEccccccHHHHHHHHHHHHHcccccEEEEEccccHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHHHcccccEEEEccccHHHHHHHHHHHcccccEEEEEEcccHHHHHHHHHHHccccccEEEEEcccccccccHHHHHHHHHHccccHHHHHHHHcccccHHHHHHcHHHHHHHccccccccccccHHHccccccccccccccHHHHHHHHHHHHHHHcccccccccccccEEcccccEEEEEccccccEEEEEccccHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHHcccEEcccccccEEEEEEEEcccEEEEEccccHHHHHHHHHHHHHHHHccEEEEEcccccHHHHHHHHHHHHHccccccEEEEccccHHHHHHHHHccccccEEEEEccHHHHHHHHHHHHHcccccEEEEEEccccccEEEcccccHHHHHHHHHHHHHHHcccEEEcccEEEEEcHHHHHHHHHHHHHHHHccccccccccccccccccHHHHHHHHHHHHHHHHcccEEEEccccccccccEEEccEEEEccccHHHHHcccccEEEEEEEccccHHHHHHHHcccccccEEEEEcccHHHHHHHHHHccccEEEEcccccccccccccccccccccccccccccHHHHHHHHHHHHcccccccccccccccccHHHHHHHHccccccccEEccccccccEEEEEccccccEEEEEccccHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHcHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHHHcccEEcccccccEEEEEEEcccEEEEEccccHHHHHHHHHHHHHHHHccEEEEEcccccHHHHHHHHHHHHHccccccEEEEccccHHHHHHHHHccccccEEEEEccHHHHHHHHHHHHHHcccccEEEEEccccHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHcccc //