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Lactobacillus salivarius UCC118 (lsal0)
Gene : glyA
DDBJ      :glyA         Serine hydroxymethyltransferase
Swiss-Prot:GLYA_LACS1   RecName: Full=Serine hydroxymethyltransferase;         Short=Serine methylase;         Short=SHMT;         EC=2.1.2.1;

Homologs  Archaea  61/68 : Bacteria  896/915 : Eukaryota  191/199 : Viruses  1/175   --->[See Alignment]
c.67.1
:417 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   7->406 1kkjA PDBj e-149 64.6 %
:RPS:PDB   4->412 1cj0A PDBj 4e-82 47.2 %
:RPS:SCOP  4->412 1bj4A  c.67.1.4 * e-148 46.7 %
:HMM:SCOP  2->416 2a7vA1 c.67.1.4 * 2e-174 59.8 %
:RPS:PFM   5->381 PF00464 * SHMT e-160 70.2 %
:HMM:PFM   4->381 PF00464 * SHMT 3.6e-177 62.0 376/399  
:BLT:SWISS 1->417 GLYA_LACS1 0.0 100.0 %
:PROS 217->233|PS00096|SHMT

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABD99688.1 GT:GENE glyA GT:PRODUCT Serine hydroxymethyltransferase GT:DATABASE GIB00337CH01 GT:ORG lsal0 GB:ACCESSION GIB00337CH01 GB:LOCATION complement(902617..903870) GB:FROM 902617 GB:TO 903870 GB:DIRECTION - GB:GENE glyA GB:PRODUCT Serine hydroxymethyltransferase GB:NOTE COG0112 [E] Glycine/serine hydroxymethyltransferase GB:PROTEIN_ID ABD99688.1 GB:DB_XREF GI:90821049 GB:GENE:GENE glyA LENGTH 417 SQ:AASEQ MDFKKLDPELWQAIANEEQRQQNNIELIASENIVSKNVLDAQGSVLTNKYAEGYPGRRYYGGCQFIDVVENLAIDRAKQLFGAKYVNVQPHSGSQANAAAYMSLVEPGDTIMGMDLAAGGHLTHGSPVNFSGKTYNFVSYGVDKKTEMLDYDEIARLAREHQPKLIVAGASAYSRIIDFSKFREIADEVGAKLMVDMAHIAGLVAVGLHPNPVPYADITTTTTHKTLRGPRGGMILTNDENLAKKINSNVFPGTQGGPLEHVIAGKAAAFGEALTPEFKEYGEQIIRNTQEMALCFADNEKARLVSNGSDNHLLLLDVRNFGLNGKEAEKLLDQVNITVNKNSIPFETLSPFKTSGIRIGTPAITSRGFNEEDSYQVAKLILTVLANKDDEQVLADVKRQVKELTDAHPIYAEYSIR GT:EXON 1|1-417:0| SW:ID GLYA_LACS1 SW:DE RecName: Full=Serine hydroxymethyltransferase; Short=Serine methylase; Short=SHMT; EC=2.1.2.1; SW:GN Name=glyA; OrderedLocusNames=LSL_0878; SW:KW Complete proteome; Cytoplasm; One-carbon metabolism;Pyridoxal phosphate; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->417|GLYA_LACS1|0.0|100.0|417/417| GO:SWS:NREP 3 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006730|"GO:one-carbon metabolic process"|One-carbon metabolism| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 217->233|PS00096|SHMT|PDOC00090| BL:PDB:NREP 1 BL:PDB:REP 7->406|1kkjA|e-149|64.6|398/405| RP:PDB:NREP 1 RP:PDB:REP 4->412|1cj0A|4e-82|47.2|407/464| RP:PFM:NREP 1 RP:PFM:REP 5->381|PF00464|e-160|70.2|376/378|SHMT| HM:PFM:NREP 1 HM:PFM:REP 4->381|PF00464|3.6e-177|62.0|376/399|SHMT| GO:PFM:NREP 3 GO:PFM GO:0004372|"GO:glycine hydroxymethyltransferase activity"|PF00464|IPR001085| GO:PFM GO:0006544|"GO:glycine metabolic process"|PF00464|IPR001085| GO:PFM GO:0006563|"GO:L-serine metabolic process"|PF00464|IPR001085| RP:SCP:NREP 1 RP:SCP:REP 4->412|1bj4A|e-148|46.7|407/470|c.67.1.4| HM:SCP:REP 2->416|2a7vA1|2e-174|59.8|413/0|c.67.1.4|1/1|PLP-dependent transferases| OP:NHOMO 1674 OP:NHOMOORG 1149 OP:PATTERN 1111111111111111-111111111121211111111-----1111111111111111112221-11 1111111111111111122-2111212222221111124412221111111133311211111112233311---111-111211111111111111--1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111-11-11-111111111111111111111111111111111111111111111111111111111111121111111111111121111111-11111111111111111111111-11111111111111121111121211111211111111112114112221122212111222221112211111313111111111111111211111111111111111111111111111111111122113222242222222352222123421211111121211131112111111111111111111111111111111112211111111111111111211121111111111111111111211111111111141111111112111111111111111111121111-111111111111111111-11111111111111111121112211111212121111212111111111111111111111111111111111111111211111111-11111111111111111111333333323232213221111111111111222222222221111111111111111111111111111111111111111-1111111111111111---1111111111111 1122222-52--22222222222222222222222222222222222222333322222222221222222122222-2222222222-1212111111112122222524324321222122223272AY3-648222222221-2222211121223333323222124-2223333s3333275DB2943342223 -----------------------------------1------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 413 STR:RPRED 99.0 SQ:SECSTR ccHHHHcHHHHHHHHHHHHHHHHcEEccTTcccccHHHHHHTTcGGGGcccccccccccccccTTHHHHHHHHHHHHHHHTTccTEEcccccHHHHHHHHHHHHccTTcEEEEEcTTTTccGGGcccccHHHHHcEEEEEcccTTTccccHHHHHHHHHHHcccEEEEccccccccccHHHHHHHHHHHTcEEEEEcTTTHHHHHHTccccGGGTccEEEEEccccccccccEEEEEEcccHHHHHHHHHTTTTcccccHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHHTTTcEETTccccccEEEEEGGGGTccHHHHHHHHHHTTEEcEEEccTTccccTTcccEEEEEcHHHHTTTccHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHcccccH#### DISOP:02AL 1-1,416-418| PSIPRED ccHHHccHHHHHHHHHHHHHHHcccEEEEccccccHHHHHHHHHHHHHHHcccccccccccccHHHHHHHHHHHHHHHHHHcccEEEEEEccHHHHHHHHHHHHcccccEEEEEccccccHHHHHHHHHHcccccEEEEcccccccccccHHHHHHHHHHHcccEEEEccccccccccHHHHHHHHHHcccEEEEEccHHcccHHccccccccccccEEEEEcccccccccEEEEEcccHHHHHHHHHHccccccccccHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHcccccEEEcccccccEEEEEEEcccccHHHHHHHHHHcccEEccccccccccccccccccccccHHHHHccccHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHcccccccccc //