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Lactobacillus salivarius UCC118 (lsal0)
Gene : metK
DDBJ      :metK         S-adenosylmethionine synthetase
Swiss-Prot:METK_LACS1   RecName: Full=S-adenosylmethionine synthetase;         EC=2.5.1.6;AltName: Full=Methionine adenosyltransferase;AltName: Full=AdoMet synthetase;AltName: Full=MAT;

Homologs  Archaea  2/68 : Bacteria  874/915 : Eukaryota  191/199 : Viruses  0/175   --->[See Alignment]
d.130.1
:396 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   4->391 1p7lA PDBj e-123 59.3 %
:RPS:PDB   65->313 1dxjA PDBj 1e-59 11.5 %
:RPS:SCOP  4->104 1fugA1  d.130.1.1 * 1e-31 51.5 %
:RPS:SCOP  118->243 1fugA2  d.130.1.1 * 6e-52 56.0 %
:RPS:SCOP  244->394 1fugA3  d.130.1.1 * 2e-69 63.8 %
:HMM:SCOP  3->104 1mxaA1 d.130.1.1 * 2e-45 66.7 %
:HMM:SCOP  123->243 1qm4A2 d.130.1.1 * 3.9e-51 64.5 %
:HMM:SCOP  244->389 1qm4A3 d.130.1.1 * 4.8e-77 74.5 %
:RPS:PFM   5->102 PF00438 * S-AdoMet_synt_N 5e-25 53.1 %
:RPS:PFM   123->242 PF02772 * S-AdoMet_synt_M 2e-46 65.0 %
:RPS:PFM   244->383 PF02773 * S-AdoMet_synt_C 5e-56 71.7 %
:HMM:PFM   244->383 PF02773 * S-AdoMet_synt_C 2.5e-74 72.5 138/138  
:HMM:PFM   123->242 PF02772 * S-AdoMet_synt_M 3.8e-57 64.2 120/120  
:HMM:PFM   4->102 PF00438 * S-AdoMet_synt_N 2.8e-46 67.7 99/100  
:BLT:SWISS 1->396 METK_LACS1 0.0 100.0 %
:PROS 126->136|PS00376|ADOMET_SYNTHETASE_1
:PROS 270->278|PS00377|ADOMET_SYNTHETASE_2
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABD99251.1 GT:GENE metK GT:PRODUCT S-adenosylmethionine synthetase GT:DATABASE GIB00337CH01 GT:ORG lsal0 GB:ACCESSION GIB00337CH01 GB:LOCATION 487146..488336 GB:FROM 487146 GB:TO 488336 GB:DIRECTION + GB:GENE metK GB:PRODUCT S-adenosylmethionine synthetase GB:NOTE COG0192 [H] S-adenosylmethionine synthetase GB:PROTEIN_ID ABD99251.1 GB:DB_XREF GI:90820612 GB:GENE:GENE metK LENGTH 396 SQ:AASEQ MTEKHLFTSESVSEGHPDKIADQISDSILDAMLEQDPEARVAVETTVTTGLVVVVGEVSTTAHIDIQKVVRETIKEIGYKNGKYGFDGDNCAVITAIDEQSPDIALGVDNSLEVKNGDVDPLDQIGAGDQGMMFGYAINETPELMPLPISLSHHLMKKVAEVRKNGTLAYLGPDAKAQVTVEYDDNNQPLRIDTVVLSTQHDENISLDQIRKDVMDQVITKVIPDKYLDSNTKYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYAHHGGGAFSGKDATKVDRSASYAARYIAKNIVAAGLASQVEVQISYAIGVAQPVSVSVNTFGSGKVPNQKLVDAIRKVFDLRPAGIIKMLDLRRPIYKKTAAYGHFGRTDIDLPWEKTDKINELKKELDF GT:EXON 1|1-396:0| SW:ID METK_LACS1 SW:DE RecName: Full=S-adenosylmethionine synthetase; EC=2.5.1.6;AltName: Full=Methionine adenosyltransferase;AltName: Full=AdoMet synthetase;AltName: Full=MAT; SW:GN Name=metK; OrderedLocusNames=LSL_0441; SW:KW ATP-binding; Cobalt; Complete proteome; Cytoplasm; Magnesium;Metal-binding; Nucleotide-binding; One-carbon metabolism; Potassium;Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->396|METK_LACS1|0.0|100.0|396/396| GO:SWS:NREP 6 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006730|"GO:one-carbon metabolic process"|One-carbon metabolism| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 126->136|PS00376|ADOMET_SYNTHETASE_1|PDOC00369| PROS 270->278|PS00377|ADOMET_SYNTHETASE_2|PDOC00369| SEG 38->62|earvavettvttglvvvvgevstta| SEG 263->273|yggyahhggga| BL:PDB:NREP 1 BL:PDB:REP 4->391|1p7lA|e-123|59.3|376/383| RP:PDB:NREP 1 RP:PDB:REP 65->313|1dxjA|1e-59|11.5|226/242| RP:PFM:NREP 3 RP:PFM:REP 5->102|PF00438|5e-25|53.1|98/100|S-AdoMet_synt_N| RP:PFM:REP 123->242|PF02772|2e-46|65.0|120/120|S-AdoMet_synt_M| RP:PFM:REP 244->383|PF02773|5e-56|71.7|138/138|S-AdoMet_synt_C| HM:PFM:NREP 3 HM:PFM:REP 244->383|PF02773|2.5e-74|72.5|138/138|S-AdoMet_synt_C| HM:PFM:REP 123->242|PF02772|3.8e-57|64.2|120/120|S-AdoMet_synt_M| HM:PFM:REP 4->102|PF00438|2.8e-46|67.7|99/100|S-AdoMet_synt_N| GO:PFM:NREP 9 GO:PFM GO:0004478|"GO:methionine adenosyltransferase activity"|PF00438|IPR002133| GO:PFM GO:0005524|"GO:ATP binding"|PF00438|IPR002133| GO:PFM GO:0006730|"GO:one-carbon metabolic process"|PF00438|IPR002133| GO:PFM GO:0004478|"GO:methionine adenosyltransferase activity"|PF02772|IPR002133| GO:PFM GO:0005524|"GO:ATP binding"|PF02772|IPR002133| GO:PFM GO:0006730|"GO:one-carbon metabolic process"|PF02772|IPR002133| GO:PFM GO:0004478|"GO:methionine adenosyltransferase activity"|PF02773|IPR002133| GO:PFM GO:0005524|"GO:ATP binding"|PF02773|IPR002133| GO:PFM GO:0006730|"GO:one-carbon metabolic process"|PF02773|IPR002133| RP:SCP:NREP 3 RP:SCP:REP 4->104|1fugA1|1e-31|51.5|101/102|d.130.1.1| RP:SCP:REP 118->243|1fugA2|6e-52|56.0|125/129|d.130.1.1| RP:SCP:REP 244->394|1fugA3|2e-69|63.8|149/152|d.130.1.1| HM:SCP:REP 3->104|1mxaA1|2e-45|66.7|102/102|d.130.1.1|1/1|S-adenosylmethionine synthetase| HM:SCP:REP 123->243|1qm4A2|3.9e-51|64.5|121/124|d.130.1.1|1/1|S-adenosylmethionine synthetase| HM:SCP:REP 244->389|1qm4A3|4.8e-77|74.5|141/144|d.130.1.1|1/1|S-adenosylmethionine synthetase| OP:NHOMO 1350 OP:NHOMOORG 1067 OP:PATTERN ------------------------------------------------------------------11 1221111111211111111-1111111111111111111112211111111111111111111222211111111111111111111111111111---11111111111---------------111111111112112211211111122111111111111111221111111111111111111--1111111111211111111111111111111111111111111111111111111111111111111111111111111111111111112111111121111111111111112111111111111111111121121111111121213311111111111111112111121121111111111111111111-1111111211111111111111-11111111121111111111111111111111111111111111111111111121121111111---1----2---211111111111111111111111111111111111111111111111111111111111111111111111111111112111131111111111111221111111111111111111111111111111111121122111111111111111111111111111111111-111221--11111111111112111211-111111211112111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112---11-11111111111111111111111111111111 1111111-429111111111111212111111111111111-11111-1111111111111111111111221111222211111111-11111111111111112-12337C55581242222322328J2-32412123212122221213322322-3911232A21368411111N211115358154-231116 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 391 STR:RPRED 98.7 SQ:SECSTR ccccEEEEEEEEEEccEEEEcccHHHHHHHHHHHHHHTTcccTTcEEEEEEEEEcccEEcccEHcGGGTcHHHHHHHTTTTTcTTccccccccHHHHHHHHTTcTHTTTTcHHHHHccHHHEHHHHHHHHHHHHHHHHHHTccccTTGGGcTTccccccccccccccTTccccTTccTcccHHHHHHHHHHHHHHTccTTTcTTHHHHcHHHHHHHHHHcccTTcccHHHHHTTcccccHHHHHTTccccHHHHHHHHHHHTTTTccccccHHccccccHHHHHHHHHHHHHHHHHTcccccccccTTcccccTTcccccEEEEEcTTcccccHHHHHHHHHHHccccHHHHHHHHTccccccGGGGcccccccTcTTcTTTcccHHHHHH##### DISOP:02AL 1-3| PSIPRED cccccEEEccccccccHHHHHHHHHHHHHHHHHHHcccccEEEEEEEccEEEEEEEEccccEEEcHHHHHHHHHHHccccHHHcccccccEEEEEcccccccHHHccccccccccccccccHHHccccccEEEEEEEcccccccccHHHHHHHHHHHHHHHHHHccccccccccccEEEEEEEEcccccEEEEEEEEEEEccccccHHHHHHHHHHHHHHHHccccccccccEEEEcccccEEcccccccccccccEEEEEccccccccccccccccccccHHHHHHHHHHHHHHHHHHcccccEEEEEEEEEccccccEEEEEEEcccccccHHHHHHHHHHHccccHHHHHHHccccccccccccccccccccccccccccHHHHHHHHHHHcc //