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Lactobacillus salivarius UCC118 (lsal0)
Gene : rpoA
DDBJ      :rpoA         DNA-directed RNA polymerase alpha chain
Swiss-Prot:RPOA_LACS1   RecName: Full=DNA-directed RNA polymerase subunit alpha;         Short=RNAP subunit alpha;         EC=2.7.7.6;AltName: Full=Transcriptase subunit alpha;AltName: Full=RNA polymerase subunit alpha;

Homologs  Archaea  0/68 : Bacteria  911/915 : Eukaryota  13/199 : Viruses  0/175   --->[See Alignment]
a.289.1a.60.3d.181.1d.74.3
:314 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   3->226 1ynjB PDBj 5e-58 48.9 %
:BLT:PDB   240->311 3gfkB PDBj 1e-30 86.1 %
:RPS:PDB   1->227 1bdfB PDBj 1e-71 48.9 %
:RPS:PDB   245->311 1doqA PDBj 3e-19 34.3 %
:RPS:SCOP  2->66 1bdfA1  d.74.3.1 * 2e-05 42.4 %
:RPS:SCOP  48->171 1bdfA2  d.181.1.1 * 3e-41 44.2 %
:RPS:SCOP  142->303 2q0zX1  a.289.1.1 * 5e-26 13.6 %
:HMM:SCOP  48->171 1i6vA2 d.181.1.1 * 1.3e-46 54.5 %
:HMM:SCOP  245->316 1cooA_ a.60.3.1 * 1.8e-23 55.6 %
:RPS:PFM   23->226 PF01193 * RNA_pol_L 6e-40 53.7 %
:RPS:PFM   239->300 PF03118 * RNA_pol_A_CTD 3e-14 56.5 %
:HMM:PFM   240->304 PF03118 * RNA_pol_A_CTD 9.5e-32 56.9 65/67  
:HMM:PFM   23->224 PF01193 * RNA_pol_L 4.8e-29 51.2 84/86  
:BLT:SWISS 1->314 RPOA_LACS1 e-178 100.0 %

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABE00213.1 GT:GENE rpoA GT:PRODUCT DNA-directed RNA polymerase alpha chain GT:DATABASE GIB00337CH01 GT:ORG lsal0 GB:ACCESSION GIB00337CH01 GB:LOCATION complement(1482888..1483832) GB:FROM 1482888 GB:TO 1483832 GB:DIRECTION - GB:GENE rpoA GB:PRODUCT DNA-directed RNA polymerase alpha chain GB:NOTE COG0202 [K] DNA-directed RNA polymerase, alpha subunit/40 kD subunit GB:PROTEIN_ID ABE00213.1 GB:DB_XREF GI:90821574 GB:GENE:GENE rpoA LENGTH 314 SQ:AASEQ MIEFEKPKIHKIEEDNNYGKFVIEPLERGYGTTLGNSLRRILLSSLPGAAITDVQIDGVLHEFSTIPGVLEDVTLIILNLKKVALSMESEDSQALEINVTGPMEVTAGDIQSNSDVEVLNPEQYICTVADGAELHVRMNANKGRGYVSANDNKALADDMPIGVLPIDSIYTPIERVNYQVEKTRVGQKNDYDKLTLDVWTNGSITPSEAISLSAKILTEHLALFVDLTDEAKNAEIMVEKEETHKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELTNKSEADMMKVRNLGRKSLDEVKAKLADLGLSLRHDD GT:EXON 1|1-314:0| SW:ID RPOA_LACS1 SW:DE RecName: Full=DNA-directed RNA polymerase subunit alpha; Short=RNAP subunit alpha; EC=2.7.7.6;AltName: Full=Transcriptase subunit alpha;AltName: Full=RNA polymerase subunit alpha; SW:GN Name=rpoA; OrderedLocusNames=LSL_1409; SW:KW Complete proteome; DNA-directed RNA polymerase;Nucleotidyltransferase; Transcription; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->314|RPOA_LACS1|e-178|100.0|314/314| GO:SWS:NREP 4 GO:SWS GO:0003899|"GO:DNA-directed RNA polymerase activity"|DNA-directed RNA polymerase| GO:SWS GO:0016779|"GO:nucleotidyltransferase activity"|Nucleotidyltransferase| GO:SWS GO:0006350|"GO:transcription"|Transcription| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| BL:PDB:NREP 2 BL:PDB:REP 3->226|1ynjB|5e-58|48.9|221/225| BL:PDB:REP 240->311|3gfkB|1e-30|86.1|72/76| RP:PDB:NREP 2 RP:PDB:REP 1->227|1bdfB|1e-71|48.9|225/232| RP:PDB:REP 245->311|1doqA|3e-19|34.3|67/69| RP:PFM:NREP 2 RP:PFM:REP 23->226|PF01193|6e-40|53.7|201/207|RNA_pol_L| RP:PFM:REP 239->300|PF03118|3e-14|56.5|62/67|RNA_pol_A_CTD| HM:PFM:NREP 2 HM:PFM:REP 240->304|PF03118|9.5e-32|56.9|65/67|RNA_pol_A_CTD| HM:PFM:REP 23->224|PF01193|4.8e-29|51.2|84/86|RNA_pol_L| GO:PFM:NREP 6 GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF01193|IPR011261| GO:PFM GO:0006350|"GO:transcription"|PF01193|IPR011261| GO:PFM GO:0046983|"GO:protein dimerization activity"|PF01193|IPR011261| GO:PFM GO:0003677|"GO:DNA binding"|PF03118|IPR011260| GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF03118|IPR011260| GO:PFM GO:0006350|"GO:transcription"|PF03118|IPR011260| RP:SCP:NREP 3 RP:SCP:REP 2->66|1bdfA1|2e-05|42.4|65/105|d.74.3.1| RP:SCP:REP 48->171|1bdfA2|3e-41|44.2|120/121|d.181.1.1| RP:SCP:REP 142->303|2q0zX1|5e-26|13.6|162/176|a.289.1.1| HM:SCP:REP 48->171|1i6vA2|1.3e-46|54.5|121/0|d.181.1.1|1/1|Insert subdomain of RNA polymerase alpha subunit| HM:SCP:REP 245->316|1cooA_|1.8e-23|55.6|72/0|a.60.3.1|1/1|C-terminal domain of RNA polymerase alpha subunit| OP:NHOMO 945 OP:NHOMOORG 924 OP:PATTERN -------------------------------------------------------------------- 1111111111111111111-11111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112222222221111111111111111111111111111111111112111111111111111111-11111111111111111111111111111111 22------2-----1-----------------------------------------------------------------------------------------------------------------------------------------------1----------------1-1------12111--1------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 311 STR:RPRED 99.0 SQ:SECSTR ccccccccEEEEEEcccEEEEEEEEEcTTHHHHHHHHHHHHHTTccccEEEEEEEETTcccTTcccTTccccHHHHHHHHHTccEEEccccEEEEEEEEEEEEEEEGGGccccccEEEccTTcEEEEEEEEEEEEEEEEEEEcccEEccGGGcEEccccTTTcEEccEEcccEEEEEEEccccccccccccEEEEEEEEEcccccHHHHHHHHHHHHHHHGGGGTcccccTccTcccEEEEEEcccHHHEEEHHHHHHHHHHHHHHHHTTcccHHHHHHHccccHHHcTHHHHHHHHHHHHHHHHHccccc### DISOP:02AL 231-247,312-315| PSIPRED cccccccEEEEEEccccEEEEEEEcccccHHHHHHHHHHHHHHHcccccEEEEEEEccccccccccccccccHHHHHHHHcccEEEEcccccEEEEEEEEccEEEEEHHEEcccccEEEcccEEEEEEccccEEEEEEEEEEcccEEEEHHHccccccccccEEEEccccccEEEEEEEEEEEcccccccEEEEEEEEEEcccccHHHHHHHHHHHHHHHHHHHccccccccccccccccccccccHHHcccHHHHcccHHHHHHHHHcccccHHHHHHccHHHHHHccccccccHHHHHHHHHHccccccccc //