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Lactobacillus salivarius UCC118 (lsal0)
Gene : thyA
DDBJ      :thyA         Thymidylate synthase
Swiss-Prot:TYSY_LACS1   RecName: Full=Thymidylate synthase;         Short=TS;         Short=TSase;         EC=2.1.1.45;

Homologs  Archaea  15/68 : Bacteria  610/915 : Eukaryota  181/199 : Viruses  11/175   --->[See Alignment]
d.117.1
:318 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   3->318 1lcaA PDBj e-138 69.9 %
:RPS:PDB   3->318 1bo7A PDBj e-134 69.6 %
:RPS:SCOP  6->318 1aiqA  d.117.1.1 * e-120 57.8 %
:HMM:SCOP  3->318 1tsyA_ d.117.1.1 * 6.2e-134 55.4 %
:RPS:PFM   8->317 PF00303 * Thymidylat_synt e-100 68.2 %
:HMM:PFM   5->318 PF00303 * Thymidylat_synt 7e-127 65.9 264/266  
:BLT:SWISS 1->318 TYSY_LACS1 0.0 100.0 %
:PROS 180->208|PS00091|THYMIDYLATE_SYNTHASE

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABD99518.1 GT:GENE thyA GT:PRODUCT Thymidylate synthase GT:DATABASE GIB00337CH01 GT:ORG lsal0 GB:ACCESSION GIB00337CH01 GB:LOCATION 755698..756654 GB:FROM 755698 GB:TO 756654 GB:DIRECTION + GB:GENE thyA GB:PRODUCT Thymidylate synthase GB:NOTE COG0207 [F] Thymidylate synthase GB:PROTEIN_ID ABD99518.1 GB:DB_XREF GI:90820879 GB:GENE:GENE thyA LENGTH 318 SQ:AASEQ MSIVEEPYLQLIRDILEKGHEKSDRTGTGTKSLFGYQMRFNLAEGFPLLTTKKVPFGLIKSELLWFLRGDTNIRFLLEHNNHIWDEWAFKNWVESDEYHGPDMTNFGLRAQEDDNFNKVYQDEKKKFCQKIVEDQEFANKFGNLGDVYGAQWRHWQTRNGETIDQIKDVIETIKNNPDSRRMIVTAWNPEDVPLSALPPCHTLFQFYVNDGKLSCQLYQRSADVFLGVPFNIASYALLTHMIARETGLEVGEFVHTLGDAHIYLNHLDQVNEQLQRKPNDAPTLWLNPEKKNIMDFEMEDIKVKNYHSHSAIKAPVAV GT:EXON 1|1-318:0| SW:ID TYSY_LACS1 SW:DE RecName: Full=Thymidylate synthase; Short=TS; Short=TSase; EC=2.1.1.45; SW:GN Name=thyA; OrderedLocusNames=LSL_0708; SW:KW Complete proteome; Cytoplasm; Methyltransferase;Nucleotide biosynthesis; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->318|TYSY_LACS1|0.0|100.0|318/318| GO:SWS:NREP 4 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0008168|"GO:methyltransferase activity"|Methyltransferase| GO:SWS GO:0009165|"GO:nucleotide biosynthetic process"|Nucleotide biosynthesis| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 180->208|PS00091|THYMIDYLATE_SYNTHASE|PDOC00086| BL:PDB:NREP 1 BL:PDB:REP 3->318|1lcaA|e-138|69.9|316/316| RP:PDB:NREP 1 RP:PDB:REP 3->318|1bo7A|e-134|69.6|316/316| RP:PFM:NREP 1 RP:PFM:REP 8->317|PF00303|e-100|68.2|261/264|Thymidylat_synt| HM:PFM:NREP 1 HM:PFM:REP 5->318|PF00303|7e-127|65.9|264/266|Thymidylat_synt| GO:PFM:NREP 2 GO:PFM GO:0004799|"GO:thymidylate synthase activity"|PF00303|IPR000398| GO:PFM GO:0006231|"GO:dTMP biosynthetic process"|PF00303|IPR000398| RP:SCP:NREP 1 RP:SCP:REP 6->318|1aiqA|e-120|57.8|263/265|d.117.1.1| HM:SCP:REP 3->318|1tsyA_|6.2e-134|55.4|316/316|d.117.1.1|1/1|Thymidylate synthase/dCMP hydroxymethylase| OP:NHOMO 912 OP:NHOMOORG 817 OP:PATTERN -----------------------1---11-11--1-111--1---1--1-111--------------- ----111111111111111-11112111111111111111----11111--1121111----11-------11111111---------111111111--11111111111-------------------------------------------------------------------------1-1------11111111111111111111112111111111111111111111111111111111112111111111111111111211112111111111111111111111111111111111111111111111111---11---1-1-2-11---------1--1-1----1------------11--1211111111111111111111311111111111-111111111111111111111111-1111---111111--------------11-------------------------------11111111111111111111111111111111121111111111211111121111112111111111111111111---------------------------1------------------------------1111111111111111111111111111111-1111111-11111111111111111111-11111111111111111111111111111111111211211112111111111111111111111--1111111111111111111111111111111111112111111111111111113111111111111111111111111111111111111111111111-1----------------111111------11---1-1111-------------1-1 1111--1-311-11211111111111-11111111-1211-111111111111111111111111111111111111-1111111111-1211111111111111131211212-1411-111111331381-31411-15112-111111--21121223111121111-11211121M1111112-51312111111 ---1---------------1-1-------------111-1------------------------------------------------------------------------------------------------------------------------1---1-----1-1-- STR:NPRED 318 STR:RPRED 100.0 SQ:SECSTR cccTTHHHHHHHHHHHTTcEEEccTTcccEEEEEEEEEEEETTccccccccccccHHHHHHHHHHHHTTcccTHHHHTTTccTTHHHHHHHHHTcTTccccccTTHHHHHHHcTTHHHHHHHHHHHHHHHHHHcHHHHHHHTcccccHHHHHHcEEcTTccEEcHHHHHHHHHHHcTTccccEEEcccTTTTTTccccccEEEEEEEEETTEEEEEEEEEEEETTTTHHHHHHHHHHHHHHHHHHTTcEEEEEEEEEEEEEEEGGGHHHHHHHTTcccccccEEEEccccccGGGccGGGEEEEcccccccccccccc DISOP:02AL 1-1| PSIPRED cccHHHHHHHHHHHHHHccEEccccccccEEEEEcccEEEEcccccEEEEEcccHHHHHHHHHHHHHHccccHHHHHHccccEEccccHHHHHccccccccccccccccccccccccHHHHHHHHHHHcccccHHHHHHHcccEEEcccccHHcccccccccHHHHHHHHHHHHccccccEEEEEEccHHHHHHccccccEEEEEEEEEccEEEEEEEEEEccccHHHHHHHHHHHHHHHHHHHHHccccEEEEEEEEEEEEcHHHHHHHHHHHccccccccEEEEccccccHHHcccccEEEEcccccccccccccc //