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Nocardia farcinica IFM 10152 (nfar0)
Gene : BAD55564.1
DDBJ      :             putative non-ribosomal peptide synthetase
Swiss-Prot:             

Homologs  Archaea  50/68 : Bacteria  725/915 : Eukaryota  186/199 : Viruses  0/175   --->[See Alignment]
a.28.1c.43.1c.69.1e.23.1
:3030 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   26->600 2vsqA PDBj 9e-79 35.1 %
:BLT:PDB   626->1661 2vsqA PDBj e-110 30.1 %
:BLT:PDB   1687->2877 2vsqA PDBj e-125 31.7 %
:RPS:PDB   22->524 1amuB PDBj 1e-66 30.8 %
:RPS:PDB   537->606 2cgqA PDBj 2e-10 20.0 %
:RPS:PDB   622->1048 3b30A PDBj 1e-68 9.3 %
:RPS:PDB   1068->1586 1amuA PDBj 4e-67 30.2 %
:RPS:PDB   1591->1665 1dnyA PDBj 4e-11 38.7 %
:RPS:PDB   1683->2111 3b30A PDBj 4e-61 9.1 %
:RPS:PDB   2130->2660 1amuB PDBj 5e-74 33.3 %
:RPS:PDB   2660->2737 2afdA PDBj 3e-11 25.6 %
:RPS:PDB   2763->2866 3bf8A PDBj 1e-10 16.3 %
:RPS:SCOP  22->523 1md9A  e.23.1.1 * 1e-61 20.3 %
:RPS:SCOP  529->604 1dnyA  a.28.1.2 * 9e-16 35.5 %
:RPS:SCOP  626->802 1l5aA1  c.43.1.2 * 4e-41 20.1 %
:RPS:SCOP  833->1053 1q9jA2  c.43.1.2 * 1e-17 13.0 %
:RPS:SCOP  1027->1606 1pg3A  e.23.1.1 * 9e-72 15.8 %
:RPS:SCOP  1591->1665 1dnyA  a.28.1.2 * 8e-17 38.7 %
:RPS:SCOP  1687->1863 1l5aA1  c.43.1.2 * 3e-31 15.8 %
:RPS:SCOP  1897->2029 1q9jA2  c.43.1.2 * 1e-13 12.4 %
:RPS:SCOP  2089->2680 1pg3A  e.23.1.1 * 1e-77 18.6 %
:RPS:SCOP  2668->2734 1dnyA  a.28.1.2 * 8e-18 32.8 %
:RPS:SCOP  2760->3018 1jmkC  c.69.1.22 * 9e-27 21.7 %
:HMM:SCOP  19->545 1pg4A_ e.23.1.1 * 3.8e-157 41.9 %
:HMM:SCOP  529->638 1klpA_ a.28.1.1 * 1.5e-16 32.7 %
:HMM:SCOP  626->819 1l5aA1 c.43.1.2 * 8.5e-49 43.7 %
:HMM:SCOP  808->1083 1l5aA2 c.43.1.2 * 2.3e-61 44.0 %
:HMM:SCOP  1051->1607 1pg4A_ e.23.1.1 * 5.2e-167 40.6 %
:HMM:SCOP  1591->1699 1klpA_ a.28.1.1 * 3.4e-23 35.8 %
:HMM:SCOP  1687->1882 1l5aA1 c.43.1.2 * 1.5e-49 43.3 %
:HMM:SCOP  1871->2146 1l5aA2 c.43.1.2 * 2e-58 41.9 %
:HMM:SCOP  2114->2680 1pg4A_ e.23.1.1 * 2.7e-171 38.0 %
:HMM:SCOP  2664->2739 1dnyA_ a.28.1.2 * 6e-18 48.7 %
:HMM:SCOP  2753->3019 1xktA_ c.69.1.22 * 1.6e-50 35.5 %
:RPS:PFM   50->449 PF00501 * AMP-binding 1e-41 38.0 %
:RPS:PFM   543->600 PF00550 * PP-binding 2e-05 42.4 %
:RPS:PFM   625->919 PF00668 * Condensation 9e-57 56.2 %
:RPS:PFM   1116->1501 PF00501 * AMP-binding 1e-33 34.1 %
:RPS:PFM   1605->1664 PF00550 * PP-binding 2e-04 43.5 %
:RPS:PFM   1686->1982 PF00668 * Condensation 3e-45 45.3 %
:RPS:PFM   2183->2581 PF00501 * AMP-binding 1e-39 34.4 %
:RPS:PFM   2675->2737 PF00550 * PP-binding 1e-07 47.6 %
:RPS:PFM   2770->2870 PF00975 * Thioesterase 7e-20 55.4 %
:HMM:PFM   50->453 PF00501 * AMP-binding 6.6e-109 38.9 396/418  
:HMM:PFM   1116->1515 PF00501 * AMP-binding 3e-114 37.6 396/418  
:HMM:PFM   2183->2583 PF00501 * AMP-binding 4.1e-120 37.3 397/418  
:HMM:PFM   622->923 PF00668 * Condensation 9.1e-69 39.2 293/301  
:HMM:PFM   1683->1986 PF00668 * Condensation 1.2e-69 33.8 293/301  
:HMM:PFM   541->603 PF00550 * PP-binding 1.2e-12 34.9 63/67  
:HMM:PFM   1602->1661 PF00550 * PP-binding 8.6e-14 41.7 60/67  
:HMM:PFM   2674->2735 PF00550 * PP-binding 5.9e-14 45.2 62/67  
:HMM:PFM   2771->3007 PF00975 * Thioesterase 6.6e-36 31.4 207/229  
:BLT:SWISS 22->2737 TYCC_BREPA 0.0 37.3 %
:BLT:SWISS 2761->2879 PKSR_BACSU 1e-15 39.3 %
:PROS 562->577|PS00012|PHOSPHOPANTETHEINE
:PROS 1623->1638|PS00012|PHOSPHOPANTETHEINE
:PROS 2696->2711|PS00012|PHOSPHOPANTETHEINE
:PROS 177->188|PS00455|AMP_BINDING
:PROS 1238->1249|PS00455|AMP_BINDING
:PROS 2305->2316|PS00455|AMP_BINDING
:PROS 1101->1111|PS00639|THIOL_PROTEASE_HIS
:TM
:REPEAT 3|530->603|1592->1664|2665->2737
:REPEAT 3|23->529|1093->1591|2156->2664
:REPEAT 2|604->1092|1665->2155
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAD55564.1 GT:GENE BAD55564.1 GT:PRODUCT putative non-ribosomal peptide synthetase GT:DATABASE GIB00210CH01 GT:ORG nfar0 GB:ACCESSION GIB00210CH01 GB:LOCATION 755856..764948 GB:FROM 755856 GB:TO 764948 GB:DIRECTION + GB:PRODUCT putative non-ribosomal peptide synthetase GB:PROTEIN_ID BAD55564.1 LENGTH 3030 SQ:AASEQ MTRPTRVRPARTRRPRLTALPQLMAKAVEANPAGVAVLCADAIDTLGQLTYAELDERSTRLARALIARGIGPEDLVALGIPRSVDSVLACWAVAKTGAGFVPVDPNYPADRVAHMLGDSGAVVGITVADVRDDLPGDVEWLVLDDPATVDLLAAQSGEPVTGADRVRPLLAEHPAYVIYTSGSTGLPKGVVVTQAGLASFCEEQRERYRVTEESRTLHFASPSFDASVLELLLALGGAATMVVVSPTVYGGAELAGLLRRTGVTHAFITPAALASIDPTGLDDLRVVVAGGEACPPELVRRWAVPLAGGSVREFYNGYGPTETTIMTNISEPLRPGELVTIGAPIRNVAAYVLDSRLRLVPTGVVGELYLSGAQLARGYGNRPGMTAGRFVANPFTGDGARMYRTGDLVRRTASGALEYLGRNDFQVKIRGFRIELGEIDAVLASHENVDFAVTVGHRLDNGSTILAAYVHAADGSPLDTAELTALAEQQLPAHMVPTSITVLDEIPLTPVGKLDRRALPAPALHTKEFRAPAGRFEEMVAQVFDDVVGDGSPIGAADDFFELGGNSLIATQVAARLGALLETKVPTRLIFEAPTVARLAERIAELSGQGGRTELRSGPRPERIPLSLAQQRMWFLNRFEPESAAYNIPIAIRLSGALDVPALGQAIADLVGRHEVLRTVYPETAHGPVQVILPAGDASPELEVRDVAPEQVRAAVAELLGAGFDVTREVPLRVVLFRVTAEDFVLAMSVHHISGDGSSGGPLTRDLMTAYAARAAGHAPEWAPLPVQYADYSIWQREVLGSEDDPESPAAKQIAYWRDQLAGLPDQLDLPTDRPRPAVQSFQGSVVDIRIDAELHRGLVELARAEGATLFMVVHTALAVLLARLSGGDDVAVGTPIAGRGEAVLDDLIGMFVNTLVFRSRVDGAEPFTELLARQRETDLQAFAHADVPFERLVEVLNPVRSTARHPLFQVGLSFQNLAEASLELPGLRVSGLDVDVHVSQFDLHWIVGDRYDESGAPAGMGGALTYATALFDRATAEVFVERFVRLLRAVVAAPRTAVGDLDLLEPAERQRLLVDVNATDHPLTPGTLADLLDASAAAASGHAVALVGPDGGRVSWPELDARVDSVARVLISRGVGPEDRVALALRRGVDLVVAMYAVARAGGAYVPVDPDQAAERTDYILRTAAPVLVLTDAATGFTTDIAPVLAVDGAEVAVTPPAPITDADRLAPLRPDHTAYVIFTSGSTGRPKGVAVPHAAVVNQLRWKVSEFELTADDAVLLKTAATFDLSVWEFWSAAACGGRLVIASPDGHRDPAYLTELMAREGVTTLHLVPSMLDALLTASGDALPGSLRRVLAIGEALPAASAQRALRTGTALFNLYGPTEAAVSITNHLVTEADRSTVPIGAPEWNSRVYVLDGRLRPVPVGVSGELYLAGTQLARGYFGRPELTAERFVANPFTPGARMYRTGDVVAWNAAGELDYRGRTDFQVKIRGFRIELGEIEAVLQAQPGVAAAAVAAHSDPHTGDRLVGYVVPADPAAEVDTAAIKTALATELPSYMVPSAFVVLDALPLNVNGKLDRKALPEPVFEPREFRAPTTPVEEIVAEIFTDVLGVERVGADDDFFALGGNSLIATQAAARIGAALDTEVPVRLLFEAATVAALAVRVEAQAGAGRRPALTPRPRPERIPLSPAQQRMWLLNGIDGGAAVYNIPAAVRLTGTLSVPALQQAVADVLARHEVLRTVYPAHDGTAHQVVLPVDHVVPDLTPRVVPAAALREHIAAELGTGFDVTREVPVRAVLFRVAEDPAEHVLVLVVHHIAADGWSMAPFTRDLMVAYAAREIGEAPSWQPLPVQYADFSLWQRELLGDENDPASPAARQLAYWRTALAGLPDALSLPFDRPRPAIQETAARAVAVHIDARTHRALLELARAQHATLFMVVHTALAVLLARWSRADDIAIGTPVAGRGDAALDDLVGMFVNTLVLRTRVDSATLFTELLARQRDTDLAAYANADVPFEHLVDVLNPVRSTARHPVFQVMLAFQNQARAGLELPGLSVSAMEFESEQTEYDLQLMVADGYDEHGEPTGIAGKVVYPTSLFDAATIEGFARRFERVLAALAEEPGRPVGDVDWLTDAERTEVLTTRNATAHPLDESATLVSLVATGTRIDPDAVALVDGALTDQRSEVSYAEFDARANRLARHLISLGVGPGSRVVVALHRSVDLLVAIHAVLRTGAAYVPVDPDHPAERTAYVLDLSEPSCVLTHAAADFRTERAPVLHVDALDLSGYPADPVTDADRRAPLRPADTAYILFTSGSTGRPKGVAVPHRAVANHVRWFVAEYGIGAADVSLFKTTITFDMSVWDVFVPFVTGGRVVIAGRDGHRDPRYLAEVIAAERVTVIPFVPSMLRAIVDTLDGAALDTLRVIWLAGEALSAETAAAARRVSRARLDNLYGPTETAVVTMTARVPADAAGIVPIGAPIWNVRAYVLDDRLRPVPVGVAGELYHAGIQLSHGYFGRPDLTAARFVASPFGDGERLYRTGDLVRWTTDGQVEYLGRTDFQVKVRGLRIELGEIETALLGHDAVRQAVVVVHTDAQLGDQLVGYVVPEPGGVAQDGGELDAEALRAHLAALVPSYMVPAAFVLLAELPLNANGKLDRKMLPEPEFAARSQRQARTPLERTITGVFAEVLGLESVGMDDSFFELGGNSLVATRAAARLGEELGLRVPVVWLFTTPTPAGIAGQVLGAGAAERADGAPAFDAGAAFDVLLPLRAGTGAPLFCIHPFGGIAWSFAGLAAHLGGDRPIYGLQSPALGSDETLPDSTEKWALRYLEEIRSVQPRGPYHLLGWSLGGVLAHAIAVQLQAEGEQVELLAMMDSYLRSEIAESAIPAGEAPLAELLGGLLGDDAPGVDLAVGDGVDGADPAGLARRLAELPEPFASFGADRIARVLDAAVRSATVTERYRPRRFAGELVYFAAAEDDPTGSVGAATWVDAVDGPIRTVPVPTTHWRMTTAAGLAVIGRTLDELNAAREAATDRT GT:EXON 1|1-3030:0| BL:SWS:NREP 2 BL:SWS:REP 22->2737|TYCC_BREPA|0.0|37.3|2609/6486| BL:SWS:REP 2761->2879|PKSR_BACSU|1e-15|39.3|117/2543| PROS 562->577|PS00012|PHOSPHOPANTETHEINE|PDOC00012| PROS 1623->1638|PS00012|PHOSPHOPANTETHEINE|PDOC00012| PROS 2696->2711|PS00012|PHOSPHOPANTETHEINE|PDOC00012| PROS 177->188|PS00455|AMP_BINDING|PDOC00427| PROS 1238->1249|PS00455|AMP_BINDING|PDOC00427| PROS 2305->2316|PS00455|AMP_BINDING|PDOC00427| PROS 1101->1111|PS00639|THIOL_PROTEASE_HIS|PDOC00126| TM:NTM 1 TM:REGION 226->248| NREPEAT 3 REPEAT 3|530->603|1592->1664|2665->2737| REPEAT 3|23->529|1093->1591|2156->2664| REPEAT 2|604->1092|1665->2155| SEG 2->21|trptrvrpartrrprltalp| SEG 229->239|lelllalggaa| SEG 1089->1109|ladlldasaaaasghavalvg| SEG 1502->1517|avlqaqpgvaaaavaa| SEG 1631->1641|atqaaarigaa| SEG 1750->1763|hqvvlpvdhvvpdl| SEG 1807->1815|hvlvlvvhh| SEG 2422->2442|lagealsaetaaaarrvsrar| SEG 2739->2759|gagaaeradgapafdagaafd| SEG 2882->2920|pageaplaellggllgddapgvdlavgdgvdgadpagla| BL:PDB:NREP 3 BL:PDB:REP 26->600|2vsqA|9e-79|35.1|551/1273| BL:PDB:REP 626->1661|2vsqA|e-110|30.1|997/1273| BL:PDB:REP 1687->2877|2vsqA|e-125|31.7|1116/1273| RP:PDB:NREP 9 RP:PDB:REP 22->524|1amuB|1e-66|30.8|479/508| RP:PDB:REP 537->606|2cgqA|2e-10|20.0|70/74| RP:PDB:REP 622->1048|3b30A|1e-68|9.3|408/446| RP:PDB:REP 1068->1586|1amuA|4e-67|30.2|504/509| RP:PDB:REP 1591->1665|1dnyA|4e-11|38.7|75/76| RP:PDB:REP 1683->2111|3b30A|4e-61|9.1|410/446| RP:PDB:REP 2130->2660|1amuB|5e-74|33.3|505/508| RP:PDB:REP 2660->2737|2afdA|3e-11|25.6|78/88| RP:PDB:REP 2763->2866|3bf8A|1e-10|16.3|104/255| RP:PFM:NREP 9 RP:PFM:REP 50->449|PF00501|1e-41|38.0|384/405|AMP-binding| RP:PFM:REP 543->600|PF00550|2e-05|42.4|58/67|PP-binding| RP:PFM:REP 625->919|PF00668|9e-57|56.2|283/297|Condensation| RP:PFM:REP 1116->1501|PF00501|1e-33|34.1|372/405|AMP-binding| RP:PFM:REP 1605->1664|PF00550|2e-04|43.5|60/67|PP-binding| RP:PFM:REP 1686->1982|PF00668|3e-45|45.3|286/297|Condensation| RP:PFM:REP 2183->2581|PF00501|1e-39|34.4|389/405|AMP-binding| RP:PFM:REP 2675->2737|PF00550|1e-07|47.6|63/67|PP-binding| RP:PFM:REP 2770->2870|PF00975|7e-20|55.4|101/219|Thioesterase| HM:PFM:NREP 9 HM:PFM:REP 50->453|PF00501|6.6e-109|38.9|396/418|AMP-binding| HM:PFM:REP 1116->1515|PF00501|3e-114|37.6|396/418|AMP-binding| HM:PFM:REP 2183->2583|PF00501|4.1e-120|37.3|397/418|AMP-binding| HM:PFM:REP 622->923|PF00668|9.1e-69|39.2|293/301|Condensation| HM:PFM:REP 1683->1986|PF00668|1.2e-69|33.8|293/301|Condensation| HM:PFM:REP 541->603|PF00550|1.2e-12|34.9|63/67|PP-binding| HM:PFM:REP 1602->1661|PF00550|8.6e-14|41.7|60/67|PP-binding| HM:PFM:REP 2674->2735|PF00550|5.9e-14|45.2|62/67|PP-binding| HM:PFM:REP 2771->3007|PF00975|6.6e-36|31.4|207/229|Thioesterase| GO:PFM:NREP 11 GO:PFM GO:0003824|"GO:catalytic activity"|PF00501|IPR000873| GO:PFM GO:0008152|"GO:metabolic process"|PF00501|IPR000873| GO:PFM GO:0048037|"GO:cofactor binding"|PF00550|IPR006163| GO:PFM GO:0003824|"GO:catalytic activity"|PF00501|IPR000873| GO:PFM GO:0008152|"GO:metabolic process"|PF00501|IPR000873| GO:PFM GO:0048037|"GO:cofactor binding"|PF00550|IPR006163| GO:PFM GO:0003824|"GO:catalytic activity"|PF00501|IPR000873| GO:PFM GO:0008152|"GO:metabolic process"|PF00501|IPR000873| GO:PFM GO:0048037|"GO:cofactor binding"|PF00550|IPR006163| GO:PFM GO:0009058|"GO:biosynthetic process"|PF00975|IPR001031| GO:PFM GO:0016788|"GO:hydrolase activity, acting on ester bonds"|PF00975|IPR001031| RP:SCP:NREP 11 RP:SCP:REP 22->523|1md9A|1e-61|20.3|486/536|e.23.1.1| RP:SCP:REP 529->604|1dnyA|9e-16|35.5|75/76|a.28.1.2| RP:SCP:REP 626->802|1l5aA1|4e-41|20.1|174/174|c.43.1.2| RP:SCP:REP 833->1053|1q9jA2|1e-17|13.0|207/225|c.43.1.2| RP:SCP:REP 1027->1606|1pg3A|9e-72|15.8|573/634|e.23.1.1| RP:SCP:REP 1591->1665|1dnyA|8e-17|38.7|75/76|a.28.1.2| RP:SCP:REP 1687->1863|1l5aA1|3e-31|15.8|172/174|c.43.1.2| RP:SCP:REP 1897->2029|1q9jA2|1e-13|12.4|132/225|c.43.1.2| RP:SCP:REP 2089->2680|1pg3A|1e-77|18.6|582/634|e.23.1.1| RP:SCP:REP 2668->2734|1dnyA|8e-18|32.8|67/76|a.28.1.2| RP:SCP:REP 2760->3018|1jmkC|9e-27|21.7|207/222|c.69.1.22| HM:SCP:REP 19->545|1pg4A_|3.8e-157|41.9|516/643|e.23.1.1|1/3|Acetyl-CoA synthetase-like| HM:SCP:REP 529->638|1klpA_|1.5e-16|32.7|110/115|a.28.1.1|1/3|ACP-like| HM:SCP:REP 626->819|1l5aA1|8.5e-49|43.7|174/0|c.43.1.2|1/2|CoA-dependent acyltransferases| HM:SCP:REP 808->1083|1l5aA2|2.3e-61|44.0|248/0|c.43.1.2|1/2|CoA-dependent acyltransferases| HM:SCP:REP 1051->1607|1pg4A_|5.2e-167|40.6|544/643|e.23.1.1|2/3|Acetyl-CoA synthetase-like| HM:SCP:REP 1591->1699|1klpA_|3.4e-23|35.8|109/115|a.28.1.1|2/3|ACP-like| HM:SCP:REP 1687->1882|1l5aA1|1.5e-49|43.3|171/0|c.43.1.2|2/2|CoA-dependent acyltransferases| HM:SCP:REP 1871->2146|1l5aA2|2e-58|41.9|248/0|c.43.1.2|2/2|CoA-dependent acyltransferases| HM:SCP:REP 2114->2680|1pg4A_|2.7e-171|38.0|553/643|e.23.1.1|3/3|Acetyl-CoA synthetase-like| HM:SCP:REP 2664->2739|1dnyA_|6e-18|48.7|76/76|a.28.1.2|3/3|ACP-like| HM:SCP:REP 2753->3019|1xktA_|1.6e-50|35.5|256/0|c.69.1.22|2/2|alpha/beta-Hydrolases| OP:NHOMO 8537 OP:NHOMOORG 961 OP:PATTERN 44-1--4899AA98851153542AB223114A3-21--212116466712323--------15----1 4386f764334C6AckXMM-Lf99vtNNNNNSjglggw**2WGY32264B7195C88C--ZbH3kIkiLhA--------266E--2--3311-1--1---18--2H-222--------1-11111-2-211-32-2799CC221l689B5FFF-11111121-1-14J9Y4-1-----2-1--75555--1B9Q99A9AF9CDACBDF968DDGL9AIBJDDA45333333V52556665655555554333411212212121131111111222211111112116411111111111111111111211111112211121---62222622122I277------41-8215-CB4152--831111---814F99C-----99SIa446WPVOL23332232334-BBDBAIBDAHE-9CCE68665BA6AL495BDG3444A7G22222222831-2A85------------------------------BFWC-5IIAGDLNNOMRHKKEEDHTabbaEXTCZYejS24GGF99E97O9EJSI118--1-A12222222114E673aE65455673444-4764724455645hK761221-211212-1-------11116116913475453355554A5565447464469--12752------F5KB654655C6ED954-4685568588599556555769CBRW37566767776767667A4545554--587878555474---313131556546R2B111121-111-111199AD938577F4LPKNTRKKAHFHD8IIP222122222-133C455555215554534333332111------11------------------------------------------------1C1 ----256-31--77EKRUFVObSljgnKKHHFGPVPLDDDGGFGFFNELfSTQRKFRPFBBC63221211312114223231112133-8E3RA873222426BA7-6B6K2A36394-21242G8142Hi9-78C45215136234411A2-H3675B4536I9D87AEB6B991-17X43375GEDRUEF448663A ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 2857 STR:RPRED 94.3 SQ:SECSTR #####################HHHHHHTTcccccEEEEEEcccccEEEEEHHHHHHHHHHHHHHHHTTcccTTcEEEEEccccHHHHHHHHHHHHHTcEEEEccTTccHHHHHHHHHHHTccEEEEETTTHHHHHHHGGGcTTccEEEEcEEHHHHHHHcccccccccccTTcEEEEEEcccccccccEEEEEHHHHHHHHHHHTTTTcccTTcEEEEcccTTcHHHHHHTTHHHHHHTccTTccHHHHHHHHHHccccEEEccHHHHHHHHTccTTccccTTccEEEEccccccHHHHHHHHHHHccccccccEEEEEETTTEEEEEccTTTccccTTcccEEcTTccEEEEcTTcccccTTccEEEEEEccccccTTcccEETTcHHHHHHTETcEETTEEEEEEEEEEcTTccEEEEEEGGGcEEETTEEEcHHHHHHHHHTcTEEEEEEEEEEcccEEEEEEEEEcGGGccHHHHHHHHHHHHHHHccGGGcccEEEEEccccccTTccccHHHHHHHHHHHHTHHHHTTcHHHHHHHHHHHHHHHHHHHHHHHTTcEEcccccEEccccccHcccccEEEETTEEEEEccccHHHHHcEEEEEEEEEcccTTTcccccEEccGGGGcHHHHTcEEEEEEEEEEEcccGGGHHHHHHHHHHHHHHHHHHcGGGGcEEETTcccEEEEEccccccEHHHHHTccGGGccHHHHcccccccccTTccTTcccccEEEEETEEEEEEEEETTTccHHHHHHHHHHHHHHHHTccccHTTcHHHHHHTTcccTTcccccccHHHHHHETTccccGGGTTccccTTcccccccEEEEEEEEcHHHHHHHHHHHHTTccTTcccccHHHHHHHHHHHHHHHHHTTTccTTcEEEEEEEEEcHHHHTccTTcccccEEEEEEHHHHHHccHHHHHHHHHTTccHHHHHHHHHHHHHHHHccccTTccTTTTccTTTcEEEEEcTTccGGGccTTcccEcccccccTTEEEEccccTTcccTccEEEEEEEEHHHHHHHHHcHHHHTTcEEcETTEccHHHHHHHHHHHHHHHHHHHHHHHccccccccTTccHHHHHHHHHHHcTTcEEEEEEccHHHHHHHHHHHHHHHHHHHHHHHHTTccHHcTTEEETTEEEEETTcHHHHTTcccTTccHHHHHHHHGGGGcEEEEEEEcGGGccTEccccEEEEEETcccccHEEccccccccEEEEEEEETTEEEEEEEETTcccccEEEEccccTTTcccccHHHHccTTTTHHHHHHHHHHHHHHHHHTTcTTTTTEEEcccTTcccEEEEEETccccHHHHHHHHHHHHHHTcccEETcEEEEEccTTccHHHHHHHHHHHHHHHHHTcccTTcEEEEEccccTTcccccTTcEEEEEEEccTTccccccccccccTTcccccTTccHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEccHHHHHHHHHHTcHHHTcccccccccHHHHHHHHHccEEEEEEEEEEEETTTTccccccHHHHHHHHHHHHHHHHHHHHHHHHccTTHHHHHHHHHHHHHHccTHHHHTccEEEEEEccccccccTTTTccHHHHHHHHHHHHHHHHHHHHcccGGGccEEcccEEEccccTTccccccGGGcEEEccccccTTEcccEEEEEEccTTccccEEEEEEccccccccccTTccccTTccTTHHHHHTTccEccccHHHHHHTcccccccccEEEEEEEcTTcccEEEEEccccccETTcTTcccHHHHcccccccccTTccTTcccccEEEEEEcTEEEEEEEEETTTccHHHHHHHHHHHHHHHHTccccHHHcccHHHHTTcccTTcccccccHHHHHEETTccccGGGTTccccTTcccccccEEEEEEEEcHHHHHHHHHHHHTTccTTcccccHHHHHHHHHHHHHHHEEEEEccccccHHHHHHHHHHHHHHccccHHHHHHHHTGTcTTccccHHHHHHHHHHHHHHHHHHHHHTTTTTTcccEEEEEcTTccEEEHHHHHHHHHHHHHHHTTTcEEEEEETTccccccHHHHHHHHHcccEEccGGGcccEEEEEEEEEcGGGTTTTccEEEEEEEEEccccccccGGGGccccHHHHHHHHTTcccccccTTccHHHHHHHHHHHcTTcEEEEETETTTEEEcEEHHHHHHHHHHHHHHHHHHTccTTcEEEEEccccHHHHHHHHHHHHTTcEEEEccTTccHHHHHHHHHHHcccEEEEcGccGGGGGGccccccEEEEcccccGGGcccccccccccTTcEEEEEEcccTTccccEEEEEHHHHHHHHHHHHHTccccTTcEEEEcccTTcTHHHHHHHHHHTTTcEEEEccHHHHTcHHHHHHHHHHTTccEEEEcHHHHTTccTTTTccTTTcccccEEEEEcccccHHHHHHHTTTcEEEEEEccGGGccccEEEEccccccccccccEEcTTEEEEEEcTTcccccTTccEEEEEEETTcccEETTcHHHHHHHEEEccccTTcEEEEEEEEEEEcTTccEEEEEEGGGEEEETTEEEEHHHHHHHHHTcTTEEEEEEEEEEcTTccEEEEEEEEEcccccHHHHHHHHHHHHHHHHHHHccGGGcccEEEEcccccccTTccccGGGcccccccHHHTccEGGGHHHHHcGGGHHHHHHHHHccEEEEEEcccccTHHHHHHHHHHHHTTccccGGGTTTcccHHHHHHHHEHTTcccTTTTccccccccTTcEEccccccccccEEEEccTTccTTTTHHHHHHHTTTccEEEEccTTcTTccccccccHHHHHHHHHHHHHHHTcccEEEEEETHHHHHHHHHHHHcGGGEEEEEEEccccccGGccHHH######################################################################################################################################################## DISOP:02AL 839-840, 2738-2754, 3024-3030| PSIPRED ccccHHcccccccccccccHHHHHHHHHHHccccEEEEEccccccccEEcHHHHHHHHHHHHHHHHHcccccccEEEEEEcccHHHHHHHHHHHHHccEEEEccccccHHHHHHHHHHcccEEEEEcHHHHHHHHHHccEEEEcccccccccccccccccccccccccccccccEEEEEcccccccccEEEEcHHHHHHHHHHHHHHcccccccEEEEEccHHHHHHHHHHHHHHHcccEEEEcccccccHHHHHHHHHHccccEEEEcHHHHHHHHHHcccccEEEEEEcccccHHHHHHHHHHccccccEEEEEccccHHHHHEEcccccccccccccccccccccEEEEEcccccccccccccEEEEcccHHHHHHcccHHHHHHHHHccccccccccEEEEccEEEEccccEEEEEEccccEEEEccEEccHHHHHHHHHHccccccEEEEEEEccccccEEEEEEEEcccccccHHHHHHHHHHHccHHccccEEEEcccccccccccHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHccccccccccccHHHHcccHHHHHHHHHHHHHHHcccccHHHHHccccHHHHHHHHHHHHccccccHHccccccccccccHHHHHHHHHHHHccccccEEEEEEEEEcccccHHHHHHHHHHHHHHcccEEEEEEEccccEEEEEEccccccEEEEEccccHHHHHHHHHHHHHcccccccccEEEEEEEEEccccEEEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHccccccccccccccccccccccccEEEEEccHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHcccccEEEEEEEccccHHHHHHHHHHHHcEEEEEEEEcccccHHHHHHHHHHHHHHHHHHHcccHHHHHHHHccccccccccccEEEEEEcccccccccccccEEEEEEcccccccccEEEEEEEcccccccccEEEEEEEEccccccHHHHHHHHHHHHHHHHHHHccccccHHHcccccHHHHHHHHHHcccccccccHHHHHHHHHHHHHHcccccEEEEEccccEEcHHHHHHHHHHHHHHHHHcccccccEEEEEEcccHHHHHHHHHHHHHccEEEEccccccHHHHHHHHHHcccEEEEEccHHHcccccccEEEEEccccccccccccccccccccccccccEEEEEEccccccccEEEEcHHHHHHHHHHHHHHcccccccEEEEEcccHHHHHHHHHHHHHHHccEEEEEccHHcccHHHHHHHHHHccccEEEEcHHHHHHHHHcccccccccccEEEEccccccHHHHHHHHHcccEEEEccccccHHHEEEEEcccccccccccccccccccEEEEEcccccccccccEEEEEEcccHHHHHHcccHHHHHHHHHcccccccccEEEEccEEEEccccEEEEEEEcccEEEEccEEccHHHHHHHHHHcccccEEEEEEEEccccccEEEEEEEEccccccccHHHHHHHHHHHcHHHccccEEEEccccccccccHHHHHHHHHHHHccccccccccHHHHHHHHHHHHHHccccccccccHHHHcccHHHHHHHHHHHHHHccccccHHHHHccccHHHHHHHHHHHHHHHHHHHcccccccccccccHHHHHHHHHHHccccccccEEEEEEEEcccccHHHHHHHHHHHHHHcccEEEEEEEcccEEEEEEEcccccEEEEccccccHHHHHHHHHHHHHccccccccccEEEEEEEEccccccEEEEEEccHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHccccccccccccccccccccccccEEEEEccHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHcccccEEEEEEccccccHHHHHHHHHHHcEEEEEEEEcccccHHHHHHHHHHHHHHHHHHccccHHHHHHHHccccccccccccEEEEEEcccccccccccccEEEEEEcccccccccEEEEEEEcccccccccEEEEEEEEccccccHHHHHHHHHHHHHHHHHHHcccccccccccccccHHHHHHHHccccccccccccccHHHHHHHHHHHccccEEEEEccccccccEEEHHHHHHHHHHHHHHHHHcccccccEEEEEEcccHHHHHHHHHHHHHccEEEEccccccHHHHHHHHHHcccEEEEEccHHHcccccccEEEEEEcccccccccccccccccccccccccEEEEEcccccccccEEEEcHHHHHHHHHHHHHHcccccccEEEEEcccHHHHHHHHHHHHHHHccEEEEEccHHcccHHHHHHHHHHccccEEEEcHHHHHHHHHHcccccccccEEEEEEcccccHHHHHHHHHHcccEEEEccccccHHHEEEEEcccccccccccccEEccccEEEEEcccccccccccccEEEEcccHHHHHHcccHHHHHHHHccccccccccEEEEccEEEEccccEEEEEEccccEEEEccEEccHHHHHHHHHHccccEEEEEEEEEccccccEEEEEEEEcccccccccccccHHHHHHHHHHHcHHHccccEEEEcccccccccccHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHccccccccccHHHHcccHHHHHHHHHHHHHHccccccHHHHHccccHHHHHHHHHHccccccccccccccccccccccccHHHccccEEEEEEcccccHHHHHHHHHHHcccccEEEEEccccccccccHHHHHHHHHHHHHHHHHHcccccEEEEEEHHHHHHHHHHHHHHHHcccEEEEEEEEcccccccccccccccHHHHHHHHHHHHHcccccHHHHHHHHHHHHccHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHccccccccEEEEEEEcccccccccHHHHHHHHcccccEEEEcccccHHHcccHHHHHHHHHHHHHHcccccHHHcc //