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Nocardia farcinica IFM 10152 (nfar0)
Gene : BAD57058.1
DDBJ      :             putative 3-hydroxy-3-methylglutaryl-CoA reductase
Swiss-Prot:             

Homologs  Archaea  56/68 : Bacteria  33/915 : Eukaryota  170/199 : Viruses  0/175   --->[See Alignment]
d.179.1
:352 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->344 1dqaD PDBj 1e-55 40.3 %
:RPS:PDB   2->337 3cd5A PDBj 7e-48 39.4 %
:RPS:SCOP  101->346 1qaxA2  d.179.1.1 * 1e-24 16.5 %
:HMM:SCOP  2->332 1hw8A2 d.179.1.1 * 2.9e-58 50.9 %
:RPS:PFM   2->343 PF00368 * HMG-CoA_red 4e-58 43.0 %
:HMM:PFM   4->343 PF00368 * HMG-CoA_red 5.3e-96 43.9 330/374  
:BLT:SWISS 2->344 HMDH_SULSO 7e-64 39.3 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAD57058.1 GT:GENE BAD57058.1 GT:PRODUCT putative 3-hydroxy-3-methylglutaryl-CoA reductase GT:DATABASE GIB00210CH01 GT:ORG nfar0 GB:ACCESSION GIB00210CH01 GB:LOCATION 2385618..2386676 GB:FROM 2385618 GB:TO 2386676 GB:DIRECTION + GB:PRODUCT putative 3-hydroxy-3-methylglutaryl-CoA reductase GB:PROTEIN_ID BAD57058.1 LENGTH 352 SQ:AASEQ MNDLSYAAVPLRWVGPVRITGAVVDDAVEVPLATYESPLWPSVGRGARVTTLTERGVQATVIDDRMTRSVLFEADDAYTALVAVRGLTGRFAELQRVTEASSRYARLLDLHHQIAGNLLFLRFAFSTGDAAGHNMATLAADRLMDHIVATVPGLRHVSVSGNYCTDKKATAVNGILGRGKNVVTEILIPAEVVGQRLHTTARQVVELNIRKNLIGTLLAGGIRSANAHYANMLLAFYLATGQDAANIVEGSQGVTHAEDRGGDLYFSCTLPNLVVGTVGNGKHHGFVEEVLARLGCRDERPDGENARRLAVIAAAAVLCGELSLLAAQTNRGELMRSHTRFERSTTSTGVQP GT:EXON 1|1-352:0| BL:SWS:NREP 1 BL:SWS:REP 2->344|HMDH_SULSO|7e-64|39.3|341/409| SEG 306->318|arrlaviaaaavl| BL:PDB:NREP 1 BL:PDB:REP 2->344|1dqaD|1e-55|40.3|335/396| RP:PDB:NREP 1 RP:PDB:REP 2->337|3cd5A|7e-48|39.4|330/425| RP:PFM:NREP 1 RP:PFM:REP 2->343|PF00368|4e-58|43.0|328/367|HMG-CoA_red| HM:PFM:NREP 1 HM:PFM:REP 4->343|PF00368|5.3e-96|43.9|330/374|HMG-CoA_red| GO:PFM:NREP 4 GO:PFM GO:0004420|"GO:hydroxymethylglutaryl-CoA reductase (NADPH) activity"|PF00368|IPR002202| GO:PFM GO:0015936|"GO:coenzyme A metabolic process"|PF00368|IPR002202| GO:PFM GO:0050662|"GO:coenzyme binding"|PF00368|IPR002202| GO:PFM GO:0055114|"GO:oxidation reduction"|PF00368|IPR002202| RP:SCP:NREP 1 RP:SCP:REP 101->346|1qaxA2|1e-24|16.5|231/315|d.179.1.1| HM:SCP:REP 2->332|1hw8A2|2.9e-58|50.9|212/305|d.179.1.1|1/1|Substrate-binding domain of HMG-CoA reductase| OP:NHOMO 346 OP:NHOMOORG 259 OP:PATTERN 11-1-11111111111-111111-111111121111111111111111-111111111111------- --2---------1-----------1------1----1-----------------------------1-----------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------2----1-----------------------1----------------------------------------------------21-------------------------------------------22222--------------------------------------------------------------1111-1111111111------------------------------------------------------------------------- ----221-211-11-11112231545411111112111111111111111111511111111111111-1111112212211111111-1211112111111131212322232221112111111131381-21311111-11111111211112111--111111211111-1----------333612111----- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 341 STR:RPRED 96.9 SQ:SECSTR #cccccccccEEEEEEEEcccE##TcEEEEEEEcccTTHHHHHHHHHHHHHHTTTccEEEEEEEEEEEccEEEcccHHHHHHHHHHHHcHHHHHHHHHHTTcTTcEEcccEEEEETTEEEEEEEEEcTTcccHHHHHHHHHHHHHHHHHHcTTcEEEEccccccccccccHHHHHHccEEEEEEEEEEcHHHHHHTccccHHHHHHHHHHTTTHHHHHTTcccEEcccHHHHHHHHHHHTTccGGGHHHHTcEEEEEEEETcEEEEEEEEEEEccccccGGGGcHHHHHHHHHHTccccccTTHHHHHHHHHHHHHHHHHHHHHHHHHHTTTcccccHHHHccc######## DISOP:02AL 342-352| PSIPRED ccEEEEEEEEEEEEccEEEccEEccccEEEEEEEEcHHHHHHHHHHHHHHHHHcccEEEEEEcccccEEEEEEEccHHHHHHHHHHHHHHHHHHHHHHHcccccEEEEEEEEEEEccEEEEEEEEEcccccHHHHHHHHHHHHHHHHHHHcccEEEEEEEccccccccHHHHHcccccccEEHHHHHccHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHccccHHHHHHHHcEEEEEEEcccEEEEEEEEccEEEEEEccccccHHHHHHHHHccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHccccccccccc //