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Nocardia farcinica IFM 10152 (nfar0)
Gene : dnaE2
DDBJ      :dnaE2        putative DNA polymerase III alpha subunit
Swiss-Prot:DNAE2_NOCFA  RecName: Full=Error-prone DNA polymerase;         EC=2.7.7.7;

Homologs  Archaea  0/68 : Bacteria  908/915 : Eukaryota  3/199 : Viruses  2/175   --->[See Alignment]
a.4.6b.29.1b.40.4b.42.4c.6.3c.98.2
:1146 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   62->964 2hpiA PDBj e-113 36.0 %
:RPS:PDB   60->1092 3e0dA PDBj 0.0 32.2 %
:RPS:SCOP  63->115 2anuA1  c.6.3.1 * 8e-09 25.5 %
:RPS:SCOP  254->312 1ko7A1  c.98.2.1 * 5e-04 10.9 %
:RPS:SCOP  387->484 1r8nA  b.42.4.1 * 1e-22 15.1 %
:RPS:SCOP  511->589 1fc3A  a.4.6.3 * 9e-11 10.8 %
:RPS:SCOP  761->949 1kitA2  b.29.1.8 * 5e-43 8.4 %
:RPS:SCOP  1017->1135 1wjjA  b.40.4.3 * 1e-15 13.3 %
:HMM:SCOP  61->368 1m65A_ c.6.3.1 * 7.8e-22 27.6 %
:HMM:SCOP  1042->1138 1c0aA1 b.40.4.1 * 0.00011 28.7 %
:RPS:PFM   63->206 PF02811 * PHP 4e-17 41.1 %
:RPS:PFM   396->808 PF07733 * DNA_pol3_alpha 1e-99 46.3 %
:HMM:PFM   396->808 PF07733 * DNA_pol3_alpha 6.3e-144 44.0 407/422  
:HMM:PFM   64->281 PF02811 * PHP 8.4e-31 31.1 167/175  
:HMM:PFM   1060->1134 PF01336 * tRNA_anti 2.4e-09 28.4 74/76  
:BLT:SWISS 1->1146 DNAE2_NOCFA 0.0 100.0 %
:PROS 749->783|PS01109|RIBOSOMAL_L10
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAD55760.1 GT:GENE dnaE2 GT:PRODUCT putative DNA polymerase III alpha subunit GT:DATABASE GIB00210CH01 GT:ORG nfar0 GB:ACCESSION GIB00210CH01 GB:LOCATION 1016558..1019998 GB:FROM 1016558 GB:TO 1019998 GB:DIRECTION + GB:GENE dnaE2 GB:PRODUCT putative DNA polymerase III alpha subunit GB:PROTEIN_ID BAD55760.1 LENGTH 1146 SQ:AASEQ MGWGTGPPSWSELERVLSGRPGRTDPEAMYPGDGGDSPAWSRKREPYLAEPIRPVDRPTVPYAELHAHSAYSFLDGASQPEELVEEAVRLGLEAIALTDHDGFYGTVRFAEAAKEWGIATVFGAELSLGVARPAPRRSARKAARGRGRAVRYAATPEFEHAAAPDSAPRTGEPDPPGPHLLVLARGQEGYRRLSREIAAAHLAAGEKGVLRYDIDALTAAAGGHWHILTGCRKGHLRTALADDLAAGETGLPRAEAALRDLVERFGADRVSVELTHHGVPADDERNALLIALADRVGLPVLATTGAHFAGPEQRRRAMALAAIRARRSLDEMAGWLAPAGGAHLRSGAEMARLFAACPDAVANAVALSRECAFDLRLIAPQLPPFAVPDGHDENSWLRELVLRGAARRYGPPHANPPAYRQLEHELEVIATLGFPGYFLVVHDIVSFCERNGILCQGRGSAANSAVCFAIGITNVDPVANELLFERFLSPERDGPPDIDIDIESDRREEAIQHVYARYGREYAAQVANVITYRGKSAVRDAAKALGFSPGQQDAWSKQVSRWTGVGAETGTDIPEQVLRLAADLEGLPRHMGIHSGGMVICDRPIADVCPVEWARMAGRSVLQWDKDDCAAVGLVKFDMLGLGMLSALHYMIDLVREHEGVEVRLHELDLKEPAVYEMLSRADSVGVFQVESRAQMATLPRLRPREFYDLVVEVALIRPGPIQGGSVHPYIRRRNGTEPVTYDHPALENSLGRTLGVPLFQEQLMQMAVDVAGFTAAEADQLRRAMGSKRSPERMRRLKERLYRGMAELHGITGEVADRIYEKLYAFANFGFPESHSQSFAALVFYSAWFKLHHPAAFCAGLLRAQPMGFYSPQSLVADARRHGVPVHGPDVNASLAEATLENGGREVRLGLAGVRHIGSELAERIVAARVEHGPYTSVLDLTGRVELTVAQAEALATAGAFDSVTGPSGAERSGGRRAALWAAGAAARERAHLLPGTGPAADAPALPGMSALELAAADVWATGISPGSYPTEFLRARMDELGVIPAGRLLEVRDGSRVLVGGAVTHRQRPATAAGVTFLNLEDETGMVNVVCSVGLWTRYRALAQSASALLVRGRVQNAEGAVSVVAEHLQLLSLGMGSRSRDFR GT:EXON 1|1-1146:0| SW:ID DNAE2_NOCFA SW:DE RecName: Full=Error-prone DNA polymerase; EC=2.7.7.7; SW:GN Name=dnaE2; OrderedLocusNames=NFA_9150; SW:KW Complete proteome; Cytoplasm; DNA damage; DNA repair; DNA replication;DNA-directed DNA polymerase; Nucleotidyltransferase; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->1146|DNAE2_NOCFA|0.0|100.0|1146/1146| GO:SWS:NREP 7 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006974|"GO:response to DNA damage stimulus"|DNA damage| GO:SWS GO:0006281|"GO:DNA repair"|DNA repair| GO:SWS GO:0006260|"GO:DNA replication"|DNA replication| GO:SWS GO:0003887|"GO:DNA-directed DNA polymerase activity"|DNA-directed DNA polymerase| GO:SWS GO:0016779|"GO:nucleotidyltransferase activity"|Nucleotidyltransferase| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 749->783|PS01109|RIBOSOMAL_L10|PDOC00853| SEG 130->154|varpaprrsarkaargrgravryaa| SEG 314->327|rrramalaairarr| SEG 355->366|aacpdavanava| SEG 490->509|perdgppdididiesdrree| SEG 973->992|rsggrraalwaagaaarera| BL:PDB:NREP 1 BL:PDB:REP 62->964|2hpiA|e-113|36.0|848/1143| RP:PDB:NREP 1 RP:PDB:REP 60->1092|3e0dA|0.0|32.2|970/1148| RP:PFM:NREP 2 RP:PFM:REP 63->206|PF02811|4e-17|41.1|129/177|PHP| RP:PFM:REP 396->808|PF07733|1e-99|46.3|410/428|DNA_pol3_alpha| HM:PFM:NREP 3 HM:PFM:REP 396->808|PF07733|6.3e-144|44.0|407/422|DNA_pol3_alpha| HM:PFM:REP 64->281|PF02811|8.4e-31|31.1|167/175|PHP| HM:PFM:REP 1060->1134|PF01336|2.4e-09|28.4|74/76|tRNA_anti| GO:PFM:NREP 4 GO:PFM GO:0003824|"GO:catalytic activity"|PF02811|IPR004013| GO:PFM GO:0005737|"GO:cytoplasm"|PF07733|IPR011708| GO:PFM GO:0006260|"GO:DNA replication"|PF07733|IPR011708| GO:PFM GO:0008408|"GO:3'-5' exonuclease activity"|PF07733|IPR011708| RP:SCP:NREP 6 RP:SCP:REP 63->115|2anuA1|8e-09|25.5|51/224|c.6.3.1| RP:SCP:REP 254->312|1ko7A1|5e-04|10.9|55/129|c.98.2.1| RP:SCP:REP 387->484|1r8nA|1e-22|15.1|93/185|b.42.4.1| RP:SCP:REP 511->589|1fc3A|9e-11|10.8|74/119|a.4.6.3| RP:SCP:REP 761->949|1kitA2|5e-43|8.4|179/197|b.29.1.8| RP:SCP:REP 1017->1135|1wjjA|1e-15|13.3|113/145|b.40.4.3| HM:SCP:REP 61->368|1m65A_|7.8e-22|27.6|228/0|c.6.3.1|1/1|PHP domain-like| HM:SCP:REP 1042->1138|1c0aA1|0.00011|28.7|94/0|b.40.4.1|1/1|Nucleic acid-binding proteins| OP:NHOMO 1249 OP:NHOMOORG 913 OP:PATTERN -------------------------------------------------------------------- 3222222222222222222-22112222222222222222222232222211242221112222113232111112111111211111111111111112131224141311111111111111111111-111111111111112211122111221111111111112111111111111121111111211111111111111121111111111111111111111111111111111111111112111111111111111111211111111111111111111111111111111111111111111111111111111211211111111111111-2111112111111111111211111111212322211111222223322222222122221213122223222322-4443332333232322242222333221111111124221211111111111111111111111111111111222212221242532232222333222222224222221122223422222231222211111111111111222222131111111111121211112122222212111111111111111111111111122111222121112111111111112112111111122111111111111111111111111-11111111111111111111111111111111111111211111111111111112112222111111111111111121211111111111-11111111111111111222222222222222221111111111111111111222222222222222111111111111111111111111111111-11111111111111111111111111111121 -------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------1--------------2---------- --------------1-----------------------------------------------------------------1---------------------------------------------------------------------------------------------- STR:NPRED 1097 STR:RPRED 95.7 SQ:SECSTR ################################################cccccccccccccccccccccTTcTTTccccHHHHHHHHHHHcccEEEEEEETccTTHHHHHHHHHTTTcEEEEEEEEEEEHHHHHHHHTTTTcEEEEEEEEEccTTcHHHHHHHHHcccTTccccccEEEEEEEEccHHHHHHHHHHHHHHHHTHccccccEEcHHHHHHTcTTTEEEEcccTTcHHHHHHHTTcHHcGGGccHHHHHHHHHHHHHGHGGEEEEEcccccHHHHHHHHHHHHHHHHTTccEEEccccccccGGGHHHHHHHHHHHTTccccccccccccccccccccHHHHHHHccHHHHccHHHHHHHHTcccccccTTcccccccccccccHHHHHHHHHHHHHHHHcTTTccHHHHHHHHHHHHHHHHHHTcHHHHHHHHHHHHHHHTTTccccccGGGGGcHHHHHTTcccccTTTTTccHHHHccTTcccccccEEEEETTTHHHHHHHHHHHHcTTTEEEEEEEccccHHHHHHHHHHHTTccHHHHHHHHTTccccccccccccTTTTTHHHHHHHHcTTccccEEEcccEEEEccccGGGTccEcEEcTTccEEEEEEHHHHHTTTcEEEEEEEEHHHHHHHHHHHHHHHHHcccccGGGccTTcHHHHHHHHTTccTTcTTcccHHHHHHHHHHccccHHHHHHHHHHccTTGGGTcHHHHHHHHHTTccccccTHHHHHHHHGGGTTccccHHHHHHHHHHHccccHHHHHHHHHHHHHTccTTTHHHHHHHHHHHHHHcHccccHHHHHHHHHHHHHTTccccHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHTTTcHHHHHHHHHHHHTTcccEEcccTTTcccccEEETTHHEEEcccTTcccccHHHHHHHHHHHHHccccccHHHHHHHccTTTHHHHHHHHHTTTGGGccHHHHHHHHHHHHHHHHHHHHHHTTccccccccccccccccccccHHHHHHHHHHHHcccccccGGGTcHHHHHHHccccGGGHHccccccEEEEEEEEcccEEEETTTTcccEEEEETTEEEEEcEETHHHHHHHHHccTTcEEEEEEEEEEEcccEEEEEEEEEEccHHHHHHHHTc# DISOP:02AL 1-6, 31-61, 984-1002, 1140-1146| PSIPRED cccccccccEEEEEEEEcccccccccccEEcccccccccccccccccccccccccccccccEEEEEcccccHHHHccccHHHHHHHHHHccccEEEEEcccHHHHHHHHHHHHHHccccEEEEEEEEEEccccHHHHHHHHHHHHccHHHHHHccccccccccccHHcccccccccccEEEEEEccHHHHHHHHHHHHHHHHHccccccEEEcHHHHHHHccccEEEEccccccHHHHHHHHHHHHccccHHHHHHHHHHHHHHHccccEEEEEEEcccHHHHHHHHHHHHHHHHHcccEEEEcccHHccHHHHHHHHHHHHHHcccccccccHHHccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccccccHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHcccEEcccccHHHHHHHHHHHccccccccccccEEEccccccccccEEEcccccccHHHHHHHHHHHcccccEEEEEEEccHHHHHHHHHHHHHHcccHHHHHHHHHHcccccccccHHcccHHHHHHHHHHHHcccccccccccEEEEEcccccEEEcccEEcccccEEEEEccHHHHHHcccEEEEEEccccHHHHHHHHHHHHHHccccccHHHcccccHHHHHHHHcccEEEEEEcccHHHHHHHHHcccccHHHHHHHHHcccccccccccccHHHHccccccccccccHHHHHHHccccccEEcHHHHHHHHHHHHcccHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHcccccHHHHHHHHHHHHHcccEEEccEEEEcccEEEEEccccEEEccHHHcccccHHHHHHHHHHHHcccccccHHHHHHHccccHHHHHHHHHccccccccHHHHHHHHHHHHHHHHHHHHHHHccccccccccccccccccccccHHHHHHHHHHHHcccccHHHHHHHHHHHHHHccccHHHHHccccccEEEEEEEEEEEEEEccccEEEEEEEEccccEEEEEEcHHHHHHHHHHHccccEEEEEEEEEEEccEEEEEEEEEEcccHHHHHHccccc 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