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Nocardia farcinica IFM 10152 (nfar0)
Gene : hisD
DDBJ      :hisD         putative histidinol dehydrogenase
Swiss-Prot:HISX_NOCFA   RecName: Full=Histidinol dehydrogenase;         Short=HDH;         EC=1.1.1.23;

Homologs  Archaea  53/68 : Bacteria  712/915 : Eukaryota  119/199 : Viruses  0/175   --->[See Alignment]
a.29.13c.82.1
:445 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   127->444 1kaeA PDBj 9e-34 41.4 %
:RPS:PDB   187->279 2bvcA PDBj 6e-09 6.8 %
:RPS:SCOP  58->135 3d19A2  a.29.13.1 * 4e-08 11.7 %
:RPS:SCOP  127->444 1k75A  c.82.1.2 * 2e-16 34.8 %
:HMM:SCOP  17->446 1k75A_ c.82.1.2 * 2e-66 30.3 %
:RPS:PFM   27->440 PF00815 * Histidinol_dh 2e-55 38.7 %
:HMM:PFM   23->442 PF00815 * Histidinol_dh 7.1e-161 51.6 411/413  
:BLT:SWISS 1->445 HISX_NOCFA e-178 100.0 %
:PROS 242->274|PS00611|HISOL_DEHYDROGENASE
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAD56691.1 GT:GENE hisD GT:PRODUCT putative histidinol dehydrogenase GT:DATABASE GIB00210CH01 GT:ORG nfar0 GB:ACCESSION GIB00210CH01 GB:LOCATION 2018853..2020190 GB:FROM 2018853 GB:TO 2020190 GB:DIRECTION + GB:GENE hisD GB:PRODUCT putative histidinol dehydrogenase GB:PROTEIN_ID BAD56691.1 LENGTH 445 SQ:AASEQ MTSRIELARVDLRGRTPSTAELRAALPRGGVDVDSVLHHVRPVVEAVRERGAAAALEFGEKFDGVVPATVRVPAAELARALDELDPAVRAALEESIARARRVHADQRRTDTTTEVVPGGTVTERWVPVARVGLYVPGGNAVYPSSVVMNVVPAQTAGVGSLVVASPPQANFGGLPHPTILAAAALLGVEEVWAVGGAQAVALLSYGGTDTDGAPLDPVDLITGPGNIYVTAAKRLCRGLVGIDAEAGPTEIAILADATADPAHVAADLISQAEHDVLAASVLVTDSVALADAVDAALTAQLAVVKHAERVRTALTGKQSGTVLVDDITQGLRVVDAYAAEHLEIQTADASAVAARVRSAGAVFVGPYAPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVAGHVVALADAEDLPAHGQAVTVRFEALS GT:EXON 1|1-445:0| SW:ID HISX_NOCFA SW:DE RecName: Full=Histidinol dehydrogenase; Short=HDH; EC=1.1.1.23; SW:GN Name=hisD; OrderedLocusNames=NFA_18450; SW:KW Amino-acid biosynthesis; Complete proteome; Histidine biosynthesis;Metal-binding; NAD; Oxidoreductase; Zinc. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->445|HISX_NOCFA|e-178|100.0|445/445| GO:SWS:NREP 5 GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0000105|"GO:histidine biosynthetic process"|Histidine biosynthesis| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| PROS 242->274|PS00611|HISOL_DEHYDROGENASE|PDOC00534| SEG 40->57|vrpvveavrergaaaale| SEG 73->87|paaelaraldeldpa| SEG 109->123|tdtttevvpggtvte| SEG 180->186|laaaall| SEG 255->267|adatadpahvaad| SEG 281->304|vlvtdsvaladavdaaltaqlavv| SEG 347->365|adasavaarvrsagavfvg| BL:PDB:NREP 1 BL:PDB:REP 127->444|1kaeA|9e-34|41.4|302/427| RP:PDB:NREP 1 RP:PDB:REP 187->279|2bvcA|6e-09|6.8|88/475| RP:PFM:NREP 1 RP:PFM:REP 27->440|PF00815|2e-55|38.7|406/412|Histidinol_dh| HM:PFM:NREP 1 HM:PFM:REP 23->442|PF00815|7.1e-161|51.6|411/413|Histidinol_dh| GO:PFM:NREP 4 GO:PFM GO:0000105|"GO:histidine biosynthetic process"|PF00815|IPR012131| GO:PFM GO:0004399|"GO:histidinol dehydrogenase activity"|PF00815|IPR012131| GO:PFM GO:0008270|"GO:zinc ion binding"|PF00815|IPR012131| GO:PFM GO:0051287|"GO:NAD or NADH binding"|PF00815|IPR012131| RP:SCP:NREP 2 RP:SCP:REP 58->135|3d19A2|4e-08|11.7|77/130|a.29.13.1| RP:SCP:REP 127->444|1k75A|2e-16|34.8|305/431|c.82.1.2| HM:SCP:REP 17->446|1k75A_|2e-66|30.3|406/0|c.82.1.2|1/1|ALDH-like| OP:NHOMO 979 OP:NHOMOORG 884 OP:PATTERN ---1--111111111--11-1111111111111111111111111111111111-1-111-1----11 1111111111211111111-11111311111111111122111121111111112111--111111211111111111--11111111111111-----1-111111111---------------11111111111111-111111222122211111111111111221111111111111111111111111111111111111111211111111111111111111111-11111111111111111-1----11-1---11--11----1-111-------111------------------------1----1----11-1111111-1-1111111---1-1--1111111112111111111--11111111-----111111111111111111111112111111211231-2111123212421111133321223131111111111111111-----------------------------21211111111122121111111112111111112122111111111111111121111111111111111111111-1211111111111-1111111111111111111111111111-1-------11111111111112111111111111111111111111--111111111111111111111111111-1111111111111111111111111111111111111111111111111111-11111111111111-1-----111111111111111-1111---1-11111111111111111121111111111--------111111111121111111111111111111111111111--------------------------------------1--1-111111 ------1-----11111212221232111111111111111111111111122222111111111111-1111111111111111111-11111111111111111-15-------------------------------------------------1----------------11118111112133221112111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 308 STR:RPRED 69.2 SQ:SECSTR ##############################################################################################################################EccEEEEEccccccccTHHHHH#HHHHHHHTccEEEEEEcccc######cHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHTTTcccccTTHHHHccTTccccccccEEETcTccEEEccccccTEccccccccHHHHHHHHHHHHHHHHHTTEEEEEEccHHHHHHHHHHHHHHTTcTTHHHHHHHHTT##cEEEEcccHHHHHHHHHHHcccEEEEEcTTHHHHGGGcccccEEEEcTTccHHHHHHTcccccccccTTGGGTcccccGGGGEEEE#EEEEcHHHHHHHHHHHHHHHHHTTcHHHHHHHHHHHHHH# DISOP:02AL 1-2| PSIPRED ccccHHHHHcccccccccHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHcccccEEEEcccEEEEEEEEEEccEEEEcccccccHHHHHHHHHHHHHEEcccEEEEEEcccccccccccHHHHHHHHHHHHHHHHHHccHHHHHHHHHccccccccccccccEEEccccHHHHHHHHHHccccccccccccccEEEEEcccccHHHHHHHHHHHHHcccccEEEEEEccHHHHHHHHHHHHHHHHHccHHHHHHHHHHccccEEEEEccHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHcEEEEEcccccHHHHcccccccccccccccHHHcccccHHHHccEEEEEEccHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHcc //