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Nocardia farcinica IFM 10152 (nfar0)
Gene : ilvD2
DDBJ      :ilvD2        putative dihydroxy-acid dehydratase
Swiss-Prot:ILVD2_NOCFA  RecName: Full=Dihydroxy-acid dehydratase 2;         Short=DAD 2;         EC=4.2.1.9;

Homologs  Archaea  54/68 : Bacteria  742/915 : Eukaryota  117/199 : Viruses  0/175   --->[See Alignment]
c.8.2d.334.1
:629 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   82->572 2gp4A PDBj 1e-20 31.6 %
:RPS:PDB   45->284 2cwlA PDBj 2e-28 9.5 %
:RPS:PDB   427->572 3ejfA PDBj 6e-18 16.9 %
:RPS:SCOP  49->367 2gp4A2  d.334.1.1 * 9e-77 28.9 %
:RPS:SCOP  423->610 2gp4A1  c.8.2.2 * 6e-30 29.3 %
:HMM:SCOP  4->422 2gp4A2 d.334.1.1 * 1.8e-123 44.5 %
:HMM:SCOP  423->616 2gp4A1 c.8.2.2 * 1.2e-56 55.7 %
:RPS:PFM   35->605 PF00920 * ILVD_EDD e-131 53.8 %
:HMM:PFM   35->605 PF00920 * ILVD_EDD 3.5e-191 49.8 520/521  
:BLT:SWISS 1->629 ILVD2_NOCFA 0.0 100.0 %
:PROS 123->133|PS00886|ILVD_EDD_1
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAD57230.1 GT:GENE ilvD2 GT:PRODUCT putative dihydroxy-acid dehydratase GT:DATABASE GIB00210CH01 GT:ORG nfar0 GB:ACCESSION GIB00210CH01 GB:LOCATION 2545391..2547280 GB:FROM 2545391 GB:TO 2547280 GB:DIRECTION + GB:GENE ilvD2 GB:PRODUCT putative dihydroxy-acid dehydratase GB:PROTEIN_ID BAD57230.1 LENGTH 629 SQ:AASEQ MPELRSRTVTHGRNMAGARALMRASGVPAADIGAKPVVAVANSFTEFVPGHTHLQPVGRIVGDAIRRAGGIPREFNTIAVDDGIAMGHQGMLYSLPSRDLIADSIEYMVQAHCADALVCISNCDKITPGMLLAAMRLDIPTVFVSGGPMEGGRATLADGTVRRLDLITAMSEAVNDATSDADLATIEENACPTCGSCAGMFTANSMNCLVEALGLALPGNGTTLATHTARRDLYEAAGATIMAITRRYYDRDDATVLPRAIASRAAFDNAMALDLAMGGSTNTVLHLLAAAHEAGLDYTLADIEKRSRAVPCLCKVAPNGSHLMEDVHRAGGIPAILGELRRGGHLHTTVRAVHSESLDGWLAEWDVRGPNPAQAAVDLFHAAPGGVRSATAFSQSARWAALDLDAESGCIRDVAHAYSEDGGLAVLRGNLAVDGAVVKSAGVPADLHVFTGEAVVAESQEEAVTAVLSGRVRPGTVLVIRYEGPRGGPGMQEMLYPTAYLKGRGLAGSVAVVTDGRFSGGSSGLSIGHVSPEAAAGGTIAAVTDGDPITIDIPSRTLRLEVDDAEIARRLAHRRRTGYRPRSRHRPLSTALRAYALLAQSADKGGVRRLPPDELGGPEAAFDTQTRAG GT:EXON 1|1-629:0| SW:ID ILVD2_NOCFA SW:DE RecName: Full=Dihydroxy-acid dehydratase 2; Short=DAD 2; EC=4.2.1.9; SW:GN Name=ilvD2; OrderedLocusNames=NFA_23830; SW:KW 4Fe-4S; Amino-acid biosynthesis;Branched-chain amino acid biosynthesis; Complete proteome; Iron;Iron-sulfur; Lyase; Metal-binding. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->629|ILVD2_NOCFA|0.0|100.0|629/629| GO:SWS:NREP 6 GO:SWS GO:0051539|"GO:4 iron, 4 sulfur cluster binding"|4Fe-4S| GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0009082|"GO:branched chain family amino acid biosynthetic process"|Branched-chain amino acid biosynthesis| GO:SWS GO:0051536|"GO:iron-sulfur cluster binding"|Iron-sulfur| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| PROS 123->133|PS00886|ILVD_EDD_1|PDOC00690| SEG 285->296|lhllaaaheagl| SEG 453->467|eavvaesqeeavtav| BL:PDB:NREP 1 BL:PDB:REP 82->572|2gp4A|1e-20|31.6|415/509| RP:PDB:NREP 2 RP:PDB:REP 45->284|2cwlA|2e-28|9.5|220/299| RP:PDB:REP 427->572|3ejfA|6e-18|16.9|124/166| RP:PFM:NREP 1 RP:PFM:REP 35->605|PF00920|e-131|53.8|520/521|ILVD_EDD| HM:PFM:NREP 1 HM:PFM:REP 35->605|PF00920|3.5e-191|49.8|520/521|ILVD_EDD| GO:PFM:NREP 2 GO:PFM GO:0003824|"GO:catalytic activity"|PF00920|IPR000581| GO:PFM GO:0008152|"GO:metabolic process"|PF00920|IPR000581| RP:SCP:NREP 2 RP:SCP:REP 49->367|2gp4A2|9e-77|28.9|270/332|d.334.1.1| RP:SCP:REP 423->610|2gp4A1|6e-30|29.3|181/190|c.8.2.2| HM:SCP:REP 4->422|2gp4A2|1.8e-123|44.5|382/0|d.334.1.1|1/1|IlvD/EDD N-terminal domain-like| HM:SCP:REP 423->616|2gp4A1|1.2e-56|55.7|185/0|c.8.2.2|1/1|LeuD/IlvD-like| OP:NHOMO 1757 OP:NHOMOORG 913 OP:PATTERN 11-1--1111111111-11111111--11211111111111111111111211111-----1--1-11 2131211211111121111-121114111111211133332113242-211123111111121-23423211111111-11-211111111112---11--211211212---------------11111111111111111111111111111111111111111121111111111111111111111-11111111111111111121111111111111--1111111211111111111111111112---------------------1-111-------11111111111111-------------111222111-14-23111111111121112---2-1--1211122111111111111--12135444-22-2526771134543333333333225-33433537851-5554536666775522233423444342122222251122111-----------------------------2226222552746656452222557A222223447664512552325336463982211222212232222111311-2212111111111-1111111111111-3111111111112111111111111111222243323-2322322322233332222322-1-121111111122212314222422222-2232222222233223222222211123232323333323222322222221-22222222222211-------111122246111111-111111114444423111422222223322224333311-1-11-1121312222222123222222222222221111111111--------------------------------------1--1-111131 ------1-------134224464575622222222222222222222234334424333222111111111111111-1121111111-22242222222112222--2----------------------------------------------------------------1-1111I1111111342121132332 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 554 STR:RPRED 88.1 SQ:SECSTR ##################################cccccccc##ccccHHHHHHHHGGGTTcTTcHHHHHHHHHHHHHHcccTTHHHHHHHHHHHHHHHHHHHHHHHHHcccTTccccccccccGGGcTTGGGGcccccHHHHTcccccccccTTcccccGGGccTcTTTTccccHHHHHHHHHHHHHHHHHHHHHHHTTcccHHHHHHHHHHTcccHHHHHHHHHHHHHHHHHHHHHHHHHcccGGGGccccccGcGGGcHHHHHHHHTTTTTEEEEccccccHHHHHHHHHccTTcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTcGGGcHHHHHHHHTTccccccccccHHHHHHHHHHcHHHHHH##################EEEETTEEEEEcccccTT#HHHHHHHccccccccHHHcccccHHHHHHHHHHcHcEETTHHHHHHHHHHHHHccccEEEEccccTTEEEEEEEccccTTcccHHHHHHHHHHTHHHHTcccETccTTEEEEEcccTTcTTccHHHHHHHHHHHHTTcccGGGcHHHcEEEEEEccHHHHHHHHHccEEccHHHHHHHHHHHHHHTTccEEEEccGGGTTc#################### DISOP:02AL 1-4, 617-618, 623-629| PSIPRED ccccccccccccccccHHHHHHHHccccHHHHccccEEEEEEcccccccccccHHHHHHHHHHHHHHccccEEEEcccccccccccccHHHHHHHccHHHHHHHHHHHHcccccccEEEEcccccHHHHHHHHHHHccccEEEEccccccccccccccccEEEEHHHHHHHHHHcccccHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHHHHHHHHHcccccccccHHHccHHHHHHHHHHHHHHcccHHHHHHHHHHHHHccccccHHHHHHHHHcccEEEEEccccHHHHHHHHHHccHHHHHHHHHHcccccccccccccccHHHHHccccccccccHHHHHHHHHHcccccccccccccccccccccccccccccccHHHHHcccccEEEEEccccccccEEEEcccccccEEEEEEEEEEccHHHHHHHHHccccccccEEEEEccccccccccHHHHHHHHHHHHccccccccEEEcccccccccccEEEEccHHHHccccEEEEEcccEEEEEccccEEEEEccHHHHHHHHHHHHccccccccccccHHHHHHHHHHHcccHHHcccccccHHHccccccccccccccc //