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Nocardia farcinica IFM 10152 (nfar0)
Gene : metF
DDBJ      :metF         putative 5,10-methylenetetrahydrofolate reductase
Swiss-Prot:             

Homologs  Archaea  0/68 : Bacteria  532/915 : Eukaryota  173/199 : Viruses  0/175   --->[See Alignment]
c.1.23
:321 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   24->311 1v93A PDBj 5e-49 40.8 %
:RPS:PDB   30->311 1b5tC PDBj 3e-39 32.7 %
:RPS:SCOP  30->311 1b5tA  c.1.23.1 * 9e-62 32.6 %
:HMM:SCOP  16->315 1v93A_ c.1.23.1 * 3.2e-76 42.4 %
:RPS:PFM   31->307 PF02219 * MTHFR 1e-55 46.2 %
:HMM:PFM   26->311 PF02219 * MTHFR 9.7e-84 39.7 277/287  
:BLT:SWISS 30->311 METF_STRLI 4e-78 53.3 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAD56586.1 GT:GENE metF GT:PRODUCT putative 5,10-methylenetetrahydrofolate reductase GT:DATABASE GIB00210CH01 GT:ORG nfar0 GB:ACCESSION GIB00210CH01 GB:LOCATION 1892491..1893456 GB:FROM 1892491 GB:TO 1893456 GB:DIRECTION + GB:GENE metF GB:PRODUCT putative 5,10-methylenetetrahydrofolate reductase GB:PROTEIN_ID BAD56586.1 LENGTH 321 SQ:AASEQ MTFDPAPPHAAGTPSVVQSLRAHAGRSVPFSVEFNPPRDAAGEARLWRAVREFERMHPAFVSMTYGAGGSTKDRTVRVTGQLAQETTLLPVAHLTAVGHSVAELRSLVGAYADSGIRNILVLRGDPPGDPLGEWHKHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLATDTAFLAAKLRAGAEYSITQMFFEVEHYLRLRDRLAALDPVEGAKPIIPELMPITSLRTVTRAEELCGRPLPAAVLDRLRRAAGDGPEEDRAAVREVGIEIATEMAQRLIDEGAPCLHFITLNFAKATSEVLTNLGYGVTAAPVRA GT:EXON 1|1-321:0| BL:SWS:NREP 1 BL:SWS:REP 30->311|METF_STRLI|4e-78|53.3|274/307| SEG 204->214|lrlrdrlaald| BL:PDB:NREP 1 BL:PDB:REP 24->311|1v93A|5e-49|40.8|277/292| RP:PDB:NREP 1 RP:PDB:REP 30->311|1b5tC|3e-39|32.7|260/267| RP:PFM:NREP 1 RP:PFM:REP 31->307|PF02219|1e-55|46.2|266/284|MTHFR| HM:PFM:NREP 1 HM:PFM:REP 26->311|PF02219|9.7e-84|39.7|277/287|MTHFR| GO:PFM:NREP 3 GO:PFM GO:0004489|"GO:methylenetetrahydrofolate reductase (NADPH) activity"|PF02219|IPR003171| GO:PFM GO:0006555|"GO:methionine metabolic process"|PF02219|IPR003171| GO:PFM GO:0055114|"GO:oxidation reduction"|PF02219|IPR003171| RP:SCP:NREP 1 RP:SCP:REP 30->311|1b5tA|9e-62|32.6|267/275|c.1.23.1| HM:SCP:REP 16->315|1v93A_|3.2e-76|42.4|290/0|c.1.23.1|1/1|FAD-linked oxidoreductase| OP:NHOMO 844 OP:NHOMOORG 705 OP:PATTERN -------------------------------------------------------------------- 1--111111111111---------------------11111111211-1----111-1--111-11211111111111---1-11111111211-----111-1111111---------------11111111111---1-----1----------------------------------------11---------------------------------------------------------------------111--1-11--11----1-111-------1--11111111111-------------111111111--11--1111111111--------1-1----1----11-2-1------1-1--11111-----111111111111111111111111-11111111111-111111111111111111111111111--------11111-11------------------------------1111111111111111111111111111111111111111111111111111111111111111111111111111-1111111112111-1-11---1111111--------11111---------------111-1111--1--111111111111111-1111-1111111111111111111111111111-1111111111111111111111111111111111111111111111111111-11111111111111-111111----1111-111-11-1111111111111111111111111111111111111---------1111111111111111111111111111111--111111------------------------------------1-111-1----11 ----111-21--1112222222222222222222222222222222222222222222222222222222211222222222222222-22222222222222333-2212121112111121121121491-212-11111121-111-1-111-2-11121211-----2221111-----1121122421222221 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 303 STR:RPRED 94.4 SQ:SECSTR ########HHHHHHHHHHHHHTTTcccTTEEEEEcccccHHHHHHHHHHHHHHHTTcccEEEEcccccHHHHHHHHHHHHHHHHHTcccEEEEEEcTTccHHHHHHHHHHHHHTTccEEEEEcccccTcccccccHHHHHHccHHHHHHHHHHHcccEEEEEEcTTccTTcccHHHHHHHHHHHHHHTEEEEEEcccccHHHHHHHHHHHHHHHHTTccccEEcEEcccccHHHHHHHHHHHTccccHHHHHHHTTcTcTTccTcHHHHHHHHHHHHHHHHHHHHHTTccEEEEEcTTccHHHHHHHHHHT########## DISOP:02AL 1-4, 8-24, 315-321| PSIPRED cccccccccccccHHHHHHHHHHcccccEEEEEEccccccHHHHHHHHHHHHHHHccccEEEEcccccccccccHHHHHHHHHHHcccccEEEcccccccHHHHHHHHHHHHHccccEEEEEccccccccccccccccHHHHHHHHHHHHHHHccccEEEEEEccccccccccHHHHHHHHHHHHHHccHHEEccccccHHHHHHHHHHHHHHccccccccEEEEEcccccHHHHHHHHHcccccccHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHccccEEEEEcccHHHHHHHHHHHHccccccHHccc //