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Pyrobaculum aerophilum str. IM2 (paer1)
Gene : AAL62877.1
DDBJ      :             porphobilinogen synthase (delta-aminolevulinic acid dehydratase) (hemB)
Swiss-Prot:             

Homologs  Archaea  56/68 : Bacteria  749/915 : Eukaryota  181/199 : Viruses  0/175   --->[See Alignment]
c.1.10
:336 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   21->331 1w1zA PDBj 9e-79 51.0 %
:RPS:PDB   6->329 1b4eA PDBj 6e-84 48.7 %
:RPS:SCOP  2->332 1aw5A  c.1.10.3 * e-113 37.2 %
:HMM:SCOP  1->331 1e51A_ c.1.10.3 * 2e-132 58.3 %
:RPS:PFM   5->330 PF00490 * ALAD e-108 62.5 %
:HMM:PFM   3->330 PF00490 * ALAD 8.3e-146 61.9 323/324  
:BLT:SWISS 3->327 HEM2_METJA 2e-93 55.8 %
:PROS 248->260|PS00169|D_ALA_DEHYDRATASE

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAL62877.1 GT:GENE AAL62877.1 GT:PRODUCT porphobilinogen synthase (delta-aminolevulinic acid dehydratase) (hemB) GT:DATABASE GIB00076CH01 GT:ORG paer1 GB:ACCESSION GIB00076CH01 GB:LOCATION complement(313492..314502) GB:FROM 313492 GB:TO 314502 GB:DIRECTION - GB:PRODUCT porphobilinogen synthase (delta-aminolevulinic acid dehydratase) (hemB) GB:NOTE Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin GB:PROTEIN_ID AAL62877.1 GB:DB_XREF GI:18159453 LENGTH 336 SQ:AASEQ MRFPVTRPRRLRASKLIREAVAETSLDSSDFIYPIFVKPSGPREPISSMPGQYRWPVGEELVKHVEEALSLGVNKVILFGVVPDEVKDAQGSPGYDPQGVVPKAIRLLKEAFGDKLLIFADVCLCEYTEHGHCGVVRERRGRWYVDNDETIKLYAKEAVAYADAGADFVAPSGMMDGQVAEIRKALDSHGFHDVGIMAYSAKYASAFYGPFRVAAASAPKFGDRRTYQMDPRNAYEAVKEVMLDLEEGADIVMVKPALAYLDVIKIVKTHYPWAPLAAYNVSGEYAMVKAAASLGYIDERVVTLEILTAIKRAGANLILTYHALEAARWLKEGSPF GT:EXON 1|1-336:0| BL:SWS:NREP 1 BL:SWS:REP 3->327|HEM2_METJA|2e-93|55.8|317/335| PROS 248->260|PS00169|D_ALA_DEHYDRATASE|PDOC00153| BL:PDB:NREP 1 BL:PDB:REP 21->331|1w1zA|9e-79|51.0|302/319| RP:PDB:NREP 1 RP:PDB:REP 6->329|1b4eA|6e-84|48.7|314/323| RP:PFM:NREP 1 RP:PFM:REP 5->330|PF00490|e-108|62.5|320/323|ALAD| HM:PFM:NREP 1 HM:PFM:REP 3->330|PF00490|8.3e-146|61.9|323/324|ALAD| GO:PFM:NREP 3 GO:PFM GO:0004655|"GO:porphobilinogen synthase activity"|PF00490|IPR001731| GO:PFM GO:0033014|"GO:tetrapyrrole biosynthetic process"|PF00490|IPR001731| GO:PFM GO:0046872|"GO:metal ion binding"|PF00490|IPR001731| RP:SCP:NREP 1 RP:SCP:REP 2->332|1aw5A|e-113|37.2|312/326|c.1.10.3| HM:SCP:REP 1->331|1e51A_|2e-132|58.3|326/0|c.1.10.3|1/1|Aldolase| OP:NHOMO 1084 OP:NHOMOORG 986 OP:PATTERN 11-1-11111111111-1111111111111111111111111111111111111-------111--11 1111111111111111111-111111111111111111111111111111111111111111111111111--------111111111----1------111111111111111111111111111111111111111111---11232122211111111112111321111111111111111111---11111111111111111111221111111111111111111111111111111111111111-------------11---------------------------------------------1---------11111111111111111111111211---1-11111111-11111-1-111111111-----111111111211211111111111-1121111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111222221122221211211--11111------21111111111111111-11111111111111111111121111111111111111111111111111111111111111111--1111111111111212111111-----11111111121111111111122212111111111111111111111111111111111111111111111111-111111---------------------------------------11-----111 11--111-1---1111111111111121111113211111111111111111111111111111-11111111111111111111111-12111111111111211-12-2121211111111122111382-12311111112--111-11-111211221121111111--121111L111112133121112111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 333 STR:RPRED 99.1 SQ:SECSTR ccTTTccGGGGcccHHHHHHHccccccGGGEEEEEEEEcccccEEcTTcTTcEEEEGHGGHHHHHHHHHHTTccEEEEEEEcccGGccTTcGGGGcTTcHHHHHHHHHHHHcTTccEEEEEEccTTTccccccccEETTccTcEEcHHHHHHHHHHHHHHHHHHTccEEEEccccTTHHHHHHHHHHHTTcTTcEEccccEEcccGGGHHHHHHHcccccTcccTTTcccTTcHHHHHHHHHHHHHTTcccEEEEccGGGHHHHHHHHHHcccccEEEEccHHHHHHHHHHHHTTcccHHHHHHHHHHHHHHTTccEEEcTTHHHHHHTHHcG### DISOP:02AL 1-3| PSIPRED ccccccccHHccccHHHHHHHHcccccHHHcEEEEEEEcccEEEccccccccEEccHHHHHHHHHHHHHHccccEEEEEcccccccccccHHHccccccHHHHHHHHHHHHccccEEEEEEEcccccccccccEEEEcccccEEEccHHHHHHHHHHHHHHHHHcccEEcccccccHHHHHHHHHHHHcccccHHHHHHHHHHHHHHcHHHHHHHccccccccccEEEcccccHHHHHHHHHHHHHccccEEEEccccHHHHHHHHHHHHcccccEEEEEccHHHHHHHHHHHcccccHHHHHHHHHHHHHHHcccEEHHHHHHHHHHHHHHcccc //