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Pyrobaculum aerophilum str. IM2 (paer1)
Gene : AAL63605.1
DDBJ      :             isoleucyl-tRNA synthetase
Swiss-Prot:SYI_PYRAE    RecName: Full=Isoleucyl-tRNA synthetase;         EC=6.1.1.5;AltName: Full=Isoleucine--tRNA ligase;         Short=IleRS;

Homologs  Archaea  68/68 : Bacteria  910/915 : Eukaryota  197/199 : Viruses  0/175   --->[See Alignment]
a.128.1a.27.1b.51.1c.26.1
:981 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   16->834 1ileA PDBj e-163 40.5 %
:RPS:PDB   11->869 2bteA PDBj 3e-88 18.8 %
:RPS:SCOP  11->216 1n1bA2  a.128.1.3 * 3e-26 10.5 %
:RPS:SCOP  203->399 1ffyA2  b.51.1.1 * 3e-49 36.6 %
:RPS:SCOP  395->649 1li5A2  c.26.1.1 * 5e-14 11.3 %
:RPS:SCOP  658->867 1ffyA1  a.27.1.1 * 4e-30 24.4 %
:HMM:SCOP  5->654 1ileA3 c.26.1.1 * 5.4e-120 34.9 %
:HMM:SCOP  655->888 1ffyA1 a.27.1.1 * 2.5e-40 32.9 %
:HMM:SCOP  895->980 1ffyA1 a.27.1.1 * 3e-07 18.6 %
:RPS:PFM   25->633 PF00133 * tRNA-synt_1 e-122 42.8 %
:RPS:PFM   692->834 PF08264 * Anticodon_1 2e-10 31.9 %
:HMM:PFM   22->644 PF00133 * tRNA-synt_1 2.1e-174 36.9 597/601  
:HMM:PFM   692->842 PF08264 * Anticodon_1 3.8e-30 33.8 148/152  
:BLT:SWISS 1->981 SYI_PYRAE 0.0 100.0 %
:PROS 50->61|PS00178|AA_TRNA_LIGASE_I
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAL63605.1 GT:GENE AAL63605.1 GT:PRODUCT isoleucyl-tRNA synthetase GT:DATABASE GIB00076CH01 GT:ORG paer1 GB:ACCESSION GIB00076CH01 GB:LOCATION 946044..948989 GB:FROM 946044 GB:TO 948989 GB:DIRECTION + GB:PRODUCT isoleucyl-tRNA synthetase GB:NOTE Protein synthesis; tRNA aminoacylation GB:PROTEIN_ID AAL63605.1 GB:DB_XREF GI:18160237 LENGTH 981 SQ:AASEQ MPHGDLPLPPSYRPHEVKKAVEEFWRRNRIFEKWKSWRGGPKFTFLEGPPTTNGMPHVGHIRGRTYKDVVIRFYRLLGYDVWVQGGWDMQGMPVEWEVEKKLKLRSKKDIEQFGLEKFALECNSLVEEYLAYWREWGTKRLGLWLDLENAYETRQPHYLQYAWRIVKRAHELGLLTEDYRVLWFCPRCETSLSDHEVALGYDEREDPSIYVKFRVEGGVDEYLVIWTTTPWTIVDNEAVAVHPDYVYAKVEVEVGGRREYWWLAEALVPSLMAKFGIKTWRVVETKKGVELAGVRYIHPLAEEVPERASRPHQVVTAEFVTLEQGTGLVHIAPGHGPEDFELAKKYGLPVTNSVEINGIYNELGGRYKGKHVYDVDKEVTRDLRSKGLLVFEEKIRHEYPHCWRCGSKLILRADRQWFIAISRIRDKMYAELQKVNVVPTKLRDRFDIFVQNARDWNISRSRVWGTPLPVWRCKKDGRILVIGSLEELKKLAKELPPVDDFKLVHRPWIDQVKISAHDCDEWVREPYVMDVWLDSGIAWIAAVDGENNRDLWEKLFPYDFVTEGIDQTRGWFYSLLATSVLYTGRAPYKNVLIQGLILDKHGQKMSKSKGNVIWAKDLFEKYGADPVRLYILSKVAPWEDLSFDPDEVKYVIGDLNILWNVVKFADTYMSLDGFDAEKYPLSQWLEKGLEEDKWILSELNIMISEFTNFVKNFEFHKAAALWREFVVETLSHRYIRLLRRRVWSEEPSPDKYAAYAVLHDVLKKVLILGSILVPFITEYLWQAYVRKYEKNAPESVHLAQYPAAGSYDKELIYAYRELFAVFSALAEARNKAGIKLRWPIREAYVNGAKYAERYTELLKYLGNVKEVKVGRRPDYLCVKEGELEVCVPDKIEPELYYEALARELIRRIQVMRKETGLEISDEIHVVVETNSDDIKKAVEQYRDYIARETRAVKLIIDAVSQGKEWDISGEKVKIEIRKAQA GT:EXON 1|1-981:0| SW:ID SYI_PYRAE SW:DE RecName: Full=Isoleucyl-tRNA synthetase; EC=6.1.1.5;AltName: Full=Isoleucine--tRNA ligase; Short=IleRS; SW:GN Name=ileS; OrderedLocusNames=PAE1617; SW:KW Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm;Ligase; Metal-binding; Nucleotide-binding; Protein biosynthesis; Zinc. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->981|SYI_PYRAE|0.0|100.0|981/981| GO:SWS:NREP 7 GO:SWS GO:0004812|"GO:aminoacyl-tRNA ligase activity"|Aminoacyl-tRNA synthetase| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006412|"GO:translation"|Protein biosynthesis| PROS 50->61|PS00178|AA_TRNA_LIGASE_I|PDOC00161| SEG 485->495|leelkklakel| BL:PDB:NREP 1 BL:PDB:REP 16->834|1ileA|e-163|40.5|797/821| RP:PDB:NREP 1 RP:PDB:REP 11->869|2bteA|3e-88|18.8|784/876| RP:PFM:NREP 2 RP:PFM:REP 25->633|PF00133|e-122|42.8|577/593|tRNA-synt_1| RP:PFM:REP 692->834|PF08264|2e-10|31.9|141/153|Anticodon_1| HM:PFM:NREP 2 HM:PFM:REP 22->644|PF00133|2.1e-174|36.9|597/601|tRNA-synt_1| HM:PFM:REP 692->842|PF08264|3.8e-30|33.8|148/152|Anticodon_1| GO:PFM:NREP 12 GO:PFM GO:0000166|"GO:nucleotide binding"|PF00133|IPR002300| GO:PFM GO:0004812|"GO:aminoacyl-tRNA ligase activity"|PF00133|IPR002300| GO:PFM GO:0005524|"GO:ATP binding"|PF00133|IPR002300| GO:PFM GO:0005737|"GO:cytoplasm"|PF00133|IPR002300| GO:PFM GO:0006412|"GO:translation"|PF00133|IPR002300| GO:PFM GO:0006418|"GO:tRNA aminoacylation for protein translation"|PF00133|IPR002300| GO:PFM GO:0000166|"GO:nucleotide binding"|PF08264|IPR013155| GO:PFM GO:0004812|"GO:aminoacyl-tRNA ligase activity"|PF08264|IPR013155| GO:PFM GO:0005524|"GO:ATP binding"|PF08264|IPR013155| GO:PFM GO:0005737|"GO:cytoplasm"|PF08264|IPR013155| GO:PFM GO:0006412|"GO:translation"|PF08264|IPR013155| GO:PFM GO:0006418|"GO:tRNA aminoacylation for protein translation"|PF08264|IPR013155| RP:SCP:NREP 4 RP:SCP:REP 11->216|1n1bA2|3e-26|10.5|200/315|a.128.1.3| RP:SCP:REP 203->399|1ffyA2|3e-49|36.6|186/194|b.51.1.1| RP:SCP:REP 395->649|1li5A2|5e-14|11.3|247/299|c.26.1.1| RP:SCP:REP 658->867|1ffyA1|4e-30|24.4|197/273|a.27.1.1| HM:SCP:REP 5->654|1ileA3|5.4e-120|34.9|450/453|c.26.1.1|1/1|Nucleotidylyl transferase| HM:SCP:REP 655->888|1ffyA1|2.5e-40|32.9|225/273|a.27.1.1|1/2|Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases| HM:SCP:REP 895->980|1ffyA1|3e-07|18.6|86/273|a.27.1.1|2/2|Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases|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y51644342283342244225226333347CG46463836A74644254f4443446AA4564584734 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 965 STR:RPRED 98.4 SQ:SECSTR EEEEEEEEEEcccHHHHHHHHHHHHHHHTcccccccccTTcEEEEEEccccccccccHHHHHHHHHHHHHHHHHHHTTcEEEcccccccccHHHHHHHHHTTcTEcccTTTTHHHHHHHHcHHHHHHHHHHHHHHHHHHHTTccccGGGcccTTcHHHHHHHHHHHHHHHHTTcEEEEEEEEEEETTTTEEEcGGGcTcccEEEEEEEEEEcGGGGHHHccEEEEEEccGGGGGGccEEEEcTTcTHHHHcccTTTcHHHHHHHHHHHHHHHHccHHHHTcTcTTccccEEEEEEEEcTTTcGHHHHHHcEEEEEEcTTccTTcTTcEEEEcGGGcHHHHHHHHHTTccccccEEccccEEcccGGGTTccHHHHHHHHHHHHHHHTcEEEEEEccccccccEEcTcccccccccEEEETTTEETTcEEcccTTccccccccccHHHHGGGGcHHHHEEEccccccEETTTHHHHTTcTTcccccccHHHHHHHccHHHcEccEEEEcGGGTTTHHHHHHHHHHHHHTTcccccccccccEEccEEcEEEEEEEEETTEEEccHHHHHHHcccccEEEHHHHHHTTcEEEEcTTccEEEEEcccccTTTTccccHHHHHHHccHHHHHHHHHccccTTccEEEcHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHcTHTcccccccTTccTHHHHHHHHHHHHHHHHHHHHHTTcHHHHHHHHHHHHHHHHHHHHHHHcHHHHHTTccHHHHccccHHHHHHHHHHHHHHTTTcHHHHHHHHHTTHHTTccTccccGGGTccccccccccHHHHccccEEEEEEETTEEEEEEEEcccccHHHHHHHHHTTccccHHHHHcccccEEEEETHHHHHHHHHHHHHHHHHHHTcccccTTTccccccccccccccHHHHHHccccccHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHccccH################ PSIPRED cccccccccccccHHHHHHHHHHHHHHcccccccccccccccEEEEcccccccccccHHHHHHHHHHHHHHHHHHHcccEEEccccHHHHcHHHHHHHHHHHcccccccHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHcccEEcccccEEcccHHHHHHHHHHHHHHHHcccEEEEEEEEEccccccccccHHHHHcccccccccEEEEEEEEEcccccEEEEcccccccccccEEEEEcccccEEEEEEcccccccEEEEHHHHHHHHHHHccccccEEccccccccEEEEEEEcccccccccccccEEEEEEcccccccccccEEEEcccccHHHHHHHHHHccccccccccccEEcccccccccccHHHHHHHHHHHHHHcccEEccccccccccccccccccEEEEEcccccEEHHHHHHHHHHHHHccccccHHHHHHHHHHHccccccEEEEEccccEEEEEEEEccccEEEccccHHHHHHHHHHccccccccccccccccccccccccccccEEcccEEEEEEccccccHHHccccccHHHHHcccccEEEEEEEcHHHHHHHHHHHHHHHHcccccHHHEEEccEEEccccccccccccccccHHHHHHHccHHHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccccccccccHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHcccccccccccEEEccccccccccHHHHHHHHHHHHHHHHHHHHHHHccccccccHHHHHHHHHHHHHHHHHHHHHHccccEEEEcccccEEEEEccccEEEccccccccHHHHHHHHHHHHHHHHHHHHccccccccEEEEEEccHHHHHHHHHHHHHHHHccccEEEEEEcccccccEEEEcccEEEEEEEEEcc //