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Pyrobaculum aerophilum str. IM2 (paer1)
Gene : AAL64798.1
DDBJ      :             orotate phosphoribosyltransferase (pyrE)
Swiss-Prot:PYRE_PYRAE   RecName: Full=Orotate phosphoribosyltransferase;         Short=OPRT;         Short=OPRTase;         EC=2.4.2.10;

Homologs  Archaea  60/68 : Bacteria  685/915 : Eukaryota  172/199 : Viruses  0/175   --->[See Alignment]
c.61.1
:188 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->167 2wnsB PDBj 5e-26 37.0 %
:RPS:PDB   1->185 3dezB PDBj 7e-30 28.2 %
:RPS:SCOP  15->166 1mzvA  c.61.1.1 * 1e-23 26.7 %
:HMM:SCOP  1->166 2aeeA1 c.61.1.1 * 2.6e-42 40.4 %
:RPS:PFM   48->134 PF00156 * Pribosyltran 2e-07 39.1 %
:HMM:PFM   27->135 PF00156 * Pribosyltran 2.5e-20 29.4 109/125  
:BLT:SWISS 1->188 PYRE_PYRAE e-105 99.5 %

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAL64798.1 GT:GENE AAL64798.1 GT:PRODUCT orotate phosphoribosyltransferase (pyrE) GT:DATABASE GIB00076CH01 GT:ORG paer1 GB:ACCESSION GIB00076CH01 GB:LOCATION complement(1958854..1959420) GB:FROM 1958854 GB:TO 1959420 GB:DIRECTION - GB:PRODUCT orotate phosphoribosyltransferase (pyrE) GB:NOTE Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis GB:PROTEIN_ID AAL64798.1 GB:DB_XREF GI:18161521 LENGTH 188 SQ:AASEQ MDIGAVKFGAFKLSSGLESPFYVDLRSVLGEPELFQWVIERYEAVLSGLEFDVIIGVATGGIPYASVLGYRLKKPMGYVRDEAKGYGTGRQIEGADVAGKRAAVVDDVLTTGKSVLNAIRAVRASGGEVAGVVVFLDRGQCGAEAVKREAGVYVYSVYKMRELLEELRPHIGEERYRSVLDYLSQWRC GT:EXON 1|1-188:0| SW:ID PYRE_PYRAE SW:DE RecName: Full=Orotate phosphoribosyltransferase; Short=OPRT; Short=OPRTase; EC=2.4.2.10; SW:GN Name=pyrE; OrderedLocusNames=PAE3264; SW:KW Complete proteome; Glycosyltransferase; Magnesium;Pyrimidine biosynthesis; Transferase. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->188|PYRE_PYRAE|e-105|99.5|188/193| GO:SWS:NREP 3 GO:SWS GO:0016757|"GO:transferase activity, transferring glycosyl groups"|Glycosyltransferase| GO:SWS GO:0006221|"GO:pyrimidine nucleotide biosynthetic process"|Pyrimidine biosynthesis| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| BL:PDB:NREP 1 BL:PDB:REP 2->167|2wnsB|5e-26|37.0|165/199| RP:PDB:NREP 1 RP:PDB:REP 1->185|3dezB|7e-30|28.2|174/194| RP:PFM:NREP 1 RP:PFM:REP 48->134|PF00156|2e-07|39.1|87/116|Pribosyltran| HM:PFM:NREP 1 HM:PFM:REP 27->135|PF00156|2.5e-20|29.4|109/125|Pribosyltran| GO:PFM:NREP 1 GO:PFM GO:0009116|"GO:nucleoside metabolic process"|PF00156|IPR000836| RP:SCP:NREP 1 RP:SCP:REP 15->166|1mzvA|1e-23|26.7|150/216|c.61.1.1| HM:SCP:REP 1->166|2aeeA1|2.6e-42|40.4|166/0|c.61.1.1|1/1|PRTase-like| OP:NHOMO 989 OP:NHOMOORG 917 OP:PATTERN 1111111111111111111111121--1----2111111111111111-2111111111111111-11 -1--211111111111111-1---111111111---1111-111---1-111-111111111111-1-1111111111111--1111111111111---11111111111-------1111111-----------1---11---1112212221111--111121-12222--11-----11-11-1111-111111111221221112-11111211111111111111112111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111-1---1111111-1-1---1111-11-1--1------1--11-111--111-1---------1111111111111-------------1-11-1111-111121111111111---1111111111111111111111111111---------------------------------1111111111111112111111111111111111-111111111111111111111-111111111111111-111-111-11111-1-1111111--11111-111-111111-------------1--111111111111111111111111111111--11111---11111111111111111111-11111111111111111111111111111111111111111111111111111111111111111---111111111111111111111111111--111111111111111111111111111111111111111111111111111111111111111111111111111111--------1--------------------1--------1---------1 ----111-211-1111111111111111111111111------1111111111111111111111111-1121112221221111111-1211112111-111111-121212212-1--1111111114A1-11111111-1111---11-11-112-1331211211111211111171111121421111112111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 187 STR:RPRED 99.5 SQ:SECSTR HHTTcEEEcTTccEccccccEEEcGGGGGGcHHHHHHHHHHHHHHHHcTTccEEEEETTTTHHHHHHHHHHTTccEEEEcccccccEEcccEEccccTTcEEEEEEEEEcccHHHHHHHHHHHHTTcEEEEEEEEEEcccHHHHHHHHHHTccEEEcccHHHHHHHHHTcccHHHHHHHHHHHHcTc# DISOP:02AL 188-189| PSIPRED ccccEEEEccEEEcccccccEEEEcHHHcccHHHHHHHHHHHHHHHccccccEEEEcccccHHHHHHHHHHHcccEEEEEccccccccEEEEEcccccccEEEEEHHHHHHHHHHHHHHHHHHHcccEEEEEEEEEEcccccHHHHHHHccccEEEEEEHHHHHHHHHHHccHHHHHHHHHHHHHccc //