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Pyrobaculum aerophilum str. IM2 (paer1)
Gene : AAL64821.1
DDBJ      :             acetohydroxy acid isomeroreductase (ilvC)
Swiss-Prot:ILVC_PYRAE   RecName: Full=Ketol-acid reductoisomerase;         EC=1.1.1.86;AltName: Full=Acetohydroxy-acid isomeroreductase;AltName: Full=Alpha-keto-beta-hydroxylacil reductoisomerase;

Homologs  Archaea  52/68 : Bacteria  733/915 : Eukaryota  111/199 : Viruses  0/175   --->[See Alignment]
a.100.1c.127.1c.2.1d.58.56
:328 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   3->325 1np3A PDBj 9e-84 44.3 %
:RPS:PDB   35->172 3c66A PDBj 6e-27 13.9 %
:RPS:SCOP  1->101 2a10A1  d.58.56.1 * 2e-17 17.0 %
:RPS:SCOP  86->295 1qv9A  c.127.1.1 * 1e-47 20.7 %
:HMM:SCOP  2->183 1np3A2 c.2.1.6 * 6.5e-72 60.4 %
:HMM:SCOP  184->325 1qmgA1 a.100.1.2 * 1.4e-57 61.6 %
:RPS:PFM   15->178 PF07991 * IlvN 2e-55 62.8 %
:RPS:PFM   184->325 PF01450 * IlvC 4e-37 53.2 %
:HMM:PFM   15->178 PF07991 * IlvN 3.6e-78 66.5 164/165  
:HMM:PFM   184->324 PF01450 * IlvC 2.3e-50 54.3 140/145  
:BLT:SWISS 1->328 ILVC_PYRAE 0.0 100.0 %

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAL64821.1 GT:GENE AAL64821.1 GT:PRODUCT acetohydroxy acid isomeroreductase (ilvC) GT:DATABASE GIB00076CH01 GT:ORG paer1 GB:ACCESSION GIB00076CH01 GB:LOCATION complement(1976281..1977267) GB:FROM 1976281 GB:TO 1977267 GB:DIRECTION - GB:PRODUCT acetohydroxy acid isomeroreductase (ilvC) GB:NOTE Amino acid biosynthesis; Pyruvate family GB:PROTEIN_ID AAL64821.1 GB:DB_XREF GI:18161546 LENGTH 328 SQ:AASEQ MAKIYTDREASLEPLKGKTIAVIGYGIQGRAQALNLRDSGLEVIIGLRRGGKSWELATSEGFRVYEIGEAVRKADVILVLIPDMEQPKVWQEQIAPNLKEGVVVDFAHGFNVHFGLIKPPKNIDVIMVAPKAPGKAVREEYLAGRGVPALVAVYQDYSGSALKYALALAKGIGATRAGVIETTFAEETETDLIGEQIVLVGGLMELIKKGFEVLVEMGYQPEVAYFEVLNEAKLIMDLIWQRGIYGMLNGVSDTAKYGGLTVGPRVIDENVKRKMKEAAMRVKSGEFAKEWVEEYNRGAPTLRKLMEEARTHPIEKVGEEMRKLLFGP GT:EXON 1|1-328:0| SW:ID ILVC_PYRAE SW:DE RecName: Full=Ketol-acid reductoisomerase; EC=1.1.1.86;AltName: Full=Acetohydroxy-acid isomeroreductase;AltName: Full=Alpha-keto-beta-hydroxylacil reductoisomerase; SW:GN Name=ilvC; OrderedLocusNames=PAE3298; SW:KW Amino-acid biosynthesis; Branched-chain amino acid biosynthesis;Complete proteome; NADP; Oxidoreductase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->328|ILVC_PYRAE|0.0|100.0|328/328| GO:SWS:NREP 4 GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0009082|"GO:branched chain family amino acid biosynthetic process"|Branched-chain amino acid biosynthesis| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| BL:PDB:NREP 1 BL:PDB:REP 3->325|1np3A|9e-84|44.3|323/327| RP:PDB:NREP 1 RP:PDB:REP 35->172|3c66A|6e-27|13.9|137/529| RP:PFM:NREP 2 RP:PFM:REP 15->178|PF07991|2e-55|62.8|164/165|IlvN| RP:PFM:REP 184->325|PF01450|4e-37|53.2|141/145|IlvC| HM:PFM:NREP 2 HM:PFM:REP 15->178|PF07991|3.6e-78|66.5|164/165|IlvN| HM:PFM:REP 184->324|PF01450|2.3e-50|54.3|140/145|IlvC| GO:PFM:NREP 6 GO:PFM GO:0004455|"GO:ketol-acid reductoisomerase activity"|PF07991|IPR013116| GO:PFM GO:0008652|"GO:cellular amino acid biosynthetic process"|PF07991|IPR013116| GO:PFM GO:0055114|"GO:oxidation reduction"|PF07991|IPR013116| GO:PFM GO:0004455|"GO:ketol-acid reductoisomerase activity"|PF01450|IPR000506| GO:PFM GO:0009082|"GO:branched chain family amino acid biosynthetic process"|PF01450|IPR000506| GO:PFM GO:0055114|"GO:oxidation reduction"|PF01450|IPR000506| RP:SCP:NREP 2 RP:SCP:REP 1->101|2a10A1|2e-17|17.0|88/104|d.58.56.1| RP:SCP:REP 86->295|1qv9A|1e-47|20.7|179/282|c.127.1.1| HM:SCP:REP 2->183|1np3A2|6.5e-72|60.4|182/0|c.2.1.6|1/1|NAD(P)-binding Rossmann-fold domains| HM:SCP:REP 184->325|1qmgA1|1.4e-57|61.6|138/288|a.100.1.2|1/1|6-phosphogluconate dehydrogenase C-terminal domain-like| OP:NHOMO 967 OP:NHOMOORG 896 OP:PATTERN ---1--1122222231-11111111--11111111111111111121111111111-----1--1-11 1111111111111111111-111111111111111111111111111-111111111111112111112112111222-11-111111111111---11--111111111---------------11111111111111111111111111111111111111111111111111111111111111111-11122222222122222211111122211111--1111111111111111111111111111---------------------1-111-------11111111111111-------------111111111-11-11-------1-111221---1-1--111111111111-111111--1-11111111111111111111111111111111111-11111111111-111111111111111121111111111111111111111111111---------------------------11111111111111111122211111222212111111111111111111111111111111111111111111111-1111111111111-1111111111111-1121111111111111111111111111111111111-1111111111111111111111-1-111111111111111111111111111-1111111111111111111111111111111111111111111111111111-11111111111111-----------11111111111-11111111111111111111111111111111111111-1-1111-111111111111111111111111111111111111111--------------------------------------1--1-111121 --------------1111111111111-111111111111111-1111111111111-1111111111-11111111-1111111111-24211211111111212--1------------------------------------------------------------------1111B1111122231111111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 326 STR:RPRED 99.4 SQ:SECSTR HHHHHHHHHHcHcccTTcEEEEEcccTTHHHHHHcGGGGcTTcccccccccHHHHHHHHHHTTccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTccHHHHHHEEEHcHHHHTcccTTccEEEEEEEcTTccHHTTHHHHHHHTcTTEEEEEEETTccccEEEEEETTEEHHHHHHHHHHccEEEEEHHHHHHHHcTTHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHcGGGHHHHccGGGGGGTGGGGccGGTTHHHHHHHHHHHTccTTccGGGGHHHHHHHHHHHHHHHHHHHccccHHHHHHHccHTH## DISOP:02AL 328-329| PSIPRED ccEEEEccccccccccccEEEEEEEcccHHHHHHHHHHcccEEEEEEEcccHHHHHHHHcccEEccHHHHHHcccEEEEEccHHHHHHHHHHHHHHHcccccEEEEcccccEEEccEEcccccEEEEEccccccHHHHHHHHHccccEEEEEEEEcccccHHHHHHHHHHHcccccHHHHHccHHHHHHHHHHHHHcEEcHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHcccccccHHcccHHHHHHHHHHHHHHcccHHHHHHHHHHHcccHHHHHHHHHHHccHHHHHHHHHHHHHccc //