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Pyrobaculum aerophilum str. IM2 (paer1)
Gene : AAL64893.1
DDBJ      :             2-dehydropantoate 2-reductase (ketopantoate reductase)
Swiss-Prot:PANE_PYRAE   RecName: Full=Putative 2-dehydropantoate 2-reductase;         EC=1.1.1.169;AltName: Full=Ketopantoate reductase;         Short=KPA reductase;         Short=KPR;

Homologs  Archaea  33/68 : Bacteria  319/915 : Eukaryota  55/199 : Viruses  0/175   --->[See Alignment]
a.100.1c.2.1
:279 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->274 1yonA PDBj 6e-22 31.6 %
:RPS:PDB   4->273 3egoA PDBj 1e-14 24.3 %
:RPS:SCOP  159->271 1bg6A1  a.100.1.5 * 6e-17 20.4 %
:HMM:SCOP  1->149 1ks9A2 c.2.1.6 * 4.5e-09 25.5 %
:HMM:SCOP  150->275 1ks9A1 a.100.1.7 * 1e-31 49.6 %
:RPS:PFM   4->114 PF02558 * ApbA 1e-05 38.3 %
:RPS:PFM   150->273 PF08546 * ApbA_C 2e-24 51.6 %
:HMM:PFM   150->273 PF08546 * ApbA_C 1.1e-38 53.2 124/125  
:HMM:PFM   4->130 PF02558 * ApbA 2.5e-20 33.1 127/151  
:BLT:SWISS 1->279 PANE_PYRAE e-157 100.0 %

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAL64893.1 GT:GENE AAL64893.1 GT:PRODUCT 2-dehydropantoate 2-reductase (ketopantoate reductase) GT:DATABASE GIB00076CH01 GT:ORG paer1 GB:ACCESSION GIB00076CH01 GB:LOCATION complement(2037295..2038134) GB:FROM 2037295 GB:TO 2038134 GB:DIRECTION - GB:PRODUCT 2-dehydropantoate 2-reductase (ketopantoate reductase) GB:NOTE Biosynthesis of cofactors, prosthetic groups, and carriers; Pantothenate and coenzyme A GB:PROTEIN_ID AAL64893.1 GB:DB_XREF GI:18161623 LENGTH 279 SQ:AASEQ MLRVIGLGAVGSLFTYFLNRAGVVPEVVQRRRCGEFLFCVEGDCEKLKFREGGAADDVGYTIVAVKAYDSRSVVPHLKGVAVVAQNGIGGYEEIKEAYPNSVPAVVTYGVYREGCRAELRGVGEIYLPSAVSTLAELLERGGGRVRLVEDIEPYRWLKLAVNAAINAITALLQAPNGVIISSPYAQTLALEVAQEVLNVATALGVKMPRNPVEEVLRVASATAKNLSSTARDVAACAKTEIDYINGAVVKYGEALGVATPVNKALFNLIKARESLCNSG GT:EXON 1|1-279:0| SW:ID PANE_PYRAE SW:DE RecName: Full=Putative 2-dehydropantoate 2-reductase; EC=1.1.1.169;AltName: Full=Ketopantoate reductase; Short=KPA reductase; Short=KPR; SW:GN OrderedLocusNames=PAE3409; SW:KW Complete proteome; Cytoplasm; NADP; Oxidoreductase;Pantothenate biosynthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->279|PANE_PYRAE|e-157|100.0|279/279| GO:SWS:NREP 4 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| GO:SWS GO:0015940|"GO:pantothenate biosynthetic process"|Pantothenate biosynthesis| BL:PDB:NREP 1 BL:PDB:REP 2->274|1yonA|6e-22|31.6|266/292| RP:PDB:NREP 1 RP:PDB:REP 4->273|3egoA|1e-14|24.3|267/292| RP:PFM:NREP 2 RP:PFM:REP 4->114|PF02558|1e-05|38.3|107/150|ApbA| RP:PFM:REP 150->273|PF08546|2e-24|51.6|124/125|ApbA_C| HM:PFM:NREP 2 HM:PFM:REP 150->273|PF08546|1.1e-38|53.2|124/125|ApbA_C| HM:PFM:REP 4->130|PF02558|2.5e-20|33.1|127/151|ApbA| GO:PFM:NREP 3 GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF08546|IPR013752| GO:PFM GO:0050661|"GO:NADP or NADPH binding"|PF08546|IPR013752| GO:PFM GO:0055114|"GO:oxidation reduction"|PF08546|IPR013752| RP:SCP:NREP 1 RP:SCP:REP 159->271|1bg6A1|6e-17|20.4|113/165|a.100.1.5| HM:SCP:REP 1->149|1ks9A2|4.5e-09|25.5|149/0|c.2.1.6|1/1|NAD(P)-binding Rossmann-fold domains| HM:SCP:REP 150->275|1ks9A1|1e-31|49.6|123/124|a.100.1.7|1/1|6-phosphogluconate dehydrogenase C-terminal domain-like| OP:NHOMO 497 OP:NHOMOORG 407 OP:PATTERN 111-11-----------11111111111-1-111----1-1-11-12-------1111111------- --------------1--11-1----111111------------------------------------1---------------1-11----------------1--------------------------------333--------------22------------111---------------------111-----11-11-11-11----1111112-1111---1111111111221211122322211-------------------11----1111111--------------1111111111111-11---1111---2-1111111-1--111-------1--1-1-3211-------------12-1---------11----11-12------------------2-1----1-----------11-----1------111111111-1-------------------------------------2----1-1-1----11-------3---------1211-21---1211222-11-------------------12----11-1--------212--1---11-1-1-2---------------------------11121-112-111111111111111111111------------11111111111111111-11111111111111111111111111121222222222222221111111111111111111111---1----------12-------------------------------1-12111212111-1----------11111111111111------------------------------------------------------------------------- ----11------111212214524443---111-1--111111---11--1-2-1-211----1--------111--------1--------1111212----121-----------------------------------------------------------------------1----------12--1--1--- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 274 STR:RPRED 98.2 SQ:SECSTR #EEEEcccHHHHHHHHHHHTTcEEHHHHHHHHHcEEEEETTEEEEEccEEEccccccccEEEEcccGGGHHHHHHHTTccccccccHHHHHHHTcccccEEEEEEEccEEEEcccEEEEEEcccEEEEEcTTcTTTccccTTccEEEcccHHHHHHHHHHHHHHHHHHHHHHTccTTHHHHcHHHHHHHHHHHHHHHHHHTcccHHHHHHHHHHHHHHHHHTTTcccHHHHHHHHTccccHHHHHHHHHHHHHHTTcccHHHHHHHHHHHHTcTT#### DISOP:02AL 277-279| PSIPRED cEEEEEccHHHHHHHHHHHHccccEEEEEEcccccEEEEEccccEEEEEccccccccccEEEEEcccccHHHHHHHcccEEEEEEccccHHHHHHHHcccEEEEEEEEEEEEEccEEEEEEcccEEccHHHHHHHHHHHcccccEEEccHHHHHHHHHHHHHHHHHHHHHHHcccHHHHHccHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHcccccccHHHHHHHHcccccHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHccc //