[GTOP] [HELP] [ORGANISMS] [SEARCH] [SUMMARY]
Candidatus Pelagibacter ubique HTCC1062 (pubi0)
Gene : AAZ21950.1
DDBJ      :             2-isopropylmalate synthase
Swiss-Prot:             

Homologs  Archaea  56/68 : Bacteria  668/915 : Eukaryota  123/199 : Viruses  0/175   --->[See Alignment]
c.1.10d.270.1
:533 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   5->311 3bliA PDBj 9e-30 30.7 %
:RPS:PDB   3->512 3bg9A PDBj 2e-66 12.4 %
:RPS:SCOP  4->297 1sr9A2  c.1.10.5 * 5e-58 21.5 %
:RPS:SCOP  399->521 1sr9A3  d.270.1.1 * 4e-15 22.5 %
:HMM:SCOP  3->299 1sr9A2 c.1.10.5 * 9.8e-81 37.5 %
:HMM:SCOP  400->524 1sr9A3 d.270.1.1 * 3.9e-25 32.2 %
:RPS:PFM   14->249 PF00682 * HMGL-like 6e-38 41.0 %
:RPS:PFM   408->521 PF08502 * LeuA_dimer 4e-12 36.2 %
:HMM:PFM   14->249 PF00682 * HMGL-like 4e-43 33.6 229/237  
:HMM:PFM   382->523 PF08502 * LeuA_dimer 8e-29 35.7 129/133  
:HMM:PFM   332->420 PF09302 * XLF 0.00083 17.4 86/171  
:BLT:SWISS 4->528 LY41_AQUAE e-137 50.2 %
:PROS 13->29|PS00815|AIPM_HOMOCIT_SYNTH_1
:PROS 203->216|PS00816|AIPM_HOMOCIT_SYNTH_2
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAZ21950.1 GT:GENE AAZ21950.1 GT:PRODUCT 2-isopropylmalate synthase GT:DATABASE GIB00256CH01 GT:ORG pubi0 GB:ACCESSION GIB00256CH01 GB:LOCATION complement(1100004..1101605) GB:FROM 1100004 GB:TO 1101605 GB:DIRECTION - GB:PRODUCT 2-isopropylmalate synthase GB:PROTEIN_ID AAZ21950.1 GB:DB_XREF GI:71062947 LENGTH 533 SQ:AASEQ MSKEQLFIFDTTLRDGAQTQGVDFSVDDKLKIASALDNLGVDYIEGGWPGANPTDTEFFQKKHSFNNAKLTSFGMTKRTGRSADNDPGLSALLNSNTPAVCIVGKSWDFHVDIALGISNEENLENIKETAKHFVKENKEFMFDAEHFFDGYKANPSYALSCLKSAFDEGARWIVLCDTNGGTLPHEVTKIVTEVSKTIPGKNLGIHAHNDTGNAVANSLAAVWAGVRQVQGTINGLGERCGNANLMSLIPTFFLKEDFATNFQLKIKPDNIKKLTECSRLLDEILNRKPNKHLPYVGAAAFSHKGGLHVSAVQKNPKTYEHIDPVEVGNSRNIVVSDQSGKSNIISRLKTIGIEIEESDPKIKKLLDEVKDREFIGYSYDGADASFELLARRIISKIPRYILIKEYDVSVKKDSSGTIVSSAKAQLEVDGEKIMCTGEGNGPVNALDNAIRQNVDRLNKYSKYLKDLKLVDYKVRILNTGTEAITRVSIESTDSKGKNWFTIGVSANIIDASFKALVDSLDYKLFKDKAPASL GT:EXON 1|1-533:0| BL:SWS:NREP 1 BL:SWS:REP 4->528|LY41_AQUAE|e-137|50.2|516/528| PROS 13->29|PS00815|AIPM_HOMOCIT_SYNTH_1|PDOC00643| PROS 203->216|PS00816|AIPM_HOMOCIT_SYNTH_2|PDOC00643| SEG 459->474|kyskylkdlklvdykv| BL:PDB:NREP 1 BL:PDB:REP 5->311|3bliA|9e-30|30.7|296/311| RP:PDB:NREP 1 RP:PDB:REP 3->512|3bg9A|2e-66|12.4|484/601| RP:PFM:NREP 2 RP:PFM:REP 14->249|PF00682|6e-38|41.0|229/237|HMGL-like| RP:PFM:REP 408->521|PF08502|4e-12|36.2|105/132|LeuA_dimer| HM:PFM:NREP 3 HM:PFM:REP 14->249|PF00682|4e-43|33.6|229/237|HMGL-like| HM:PFM:REP 382->523|PF08502|8e-29|35.7|129/133|LeuA_dimer| HM:PFM:REP 332->420|PF09302|0.00083|17.4|86/171|XLF| GO:PFM:NREP 3 GO:PFM GO:0003824|"GO:catalytic activity"|PF00682|IPR000891| GO:PFM GO:0003852|"GO:2-isopropylmalate synthase activity"|PF08502|IPR013709| GO:PFM GO:0009098|"GO:leucine biosynthetic process"|PF08502|IPR013709| RP:SCP:NREP 2 RP:SCP:REP 4->297|1sr9A2|5e-58|21.5|284/310|c.1.10.5| RP:SCP:REP 399->521|1sr9A3|4e-15|22.5|111/115|d.270.1.1| HM:SCP:REP 3->299|1sr9A2|9.8e-81|37.5|285/0|c.1.10.5|1/1|Aldolase| HM:SCP:REP 400->524|1sr9A3|3.9e-25|32.2|115/152|d.270.1.1|1/1|2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain| OP:NHOMO 1497 OP:NHOMOORG 847 OP:PATTERN ---4--3323333333-43333322--212213333333333332333446643331-1-12-13-23 11322111------1-------11-------11111221-1223-11-2---11------112122211211111111-12-222222222232---11--2-1211222---------------33234334434322323333223423323322111111222254531111111111112323333111111111111111111111112111121121--11111143-2222221222222211111--------------------111-1--------11111-1111-----------------111111111-43-45----11-2123255----2-3--211444453333-433324--1-321111-----322232223333322222222222-11111111222-3112222222223311122232222221111111112211333-----------------------------2-11-11121-1222311-1111112111111122111211221311222221111121111111111111111123-3322333233333-333333333333312331111111111----------12111222122212-1111111111111111111111---1121-11--111211111111111111-11-1111111111111111232211211111111111111111311111111-11111111111111-1---------22112111111-111-111111111111--3-222212112----2111112--11-1211111111111111111111111111111131333333--------------------------------------3--21222322 ------1-----1121211111-2121--1111112221222212222131412212-222223433324332343333324434322-22121221112211333-131-----1------------------------------1--------1---------1-------112112H1111121212432221113 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 505 STR:RPRED 94.7 SQ:SECSTR HHccccEEEEcTTTHHHHHcTTcccHHHHHHTHHHHHHHcTTcEEEEEccHHHHHHHTcccHHHcccccEEEEcTccccccHHHHHHHHHHHHHHTccEEEEEcccccHHHHHHTHHHHHHHHTcEEEEEEEccccTcEEEEEEETcccccTTcHHHHHHHHHHHHHccccEEEEEcTTccccHHHHHHHHHHHHHHcTTccEEEEccTTcccTHHHHHHHHHTTccEEEEccGGGccTTccccHHHHHHHHTTcTTccHHHHcccccccHHHHHHHHHHHHHHHHHcGGGGcGGGTcccccTTHHHHcccHHHHHHHHHHHHHHTTcccccHHHHHHHHHHHHHHHHTTccHHHHHHGGGcccccHHHHHHHHTTcccccTTcccHHHHHHHHcccccccccTTTTcccccHHHHHHHHHTTTcccccHHHHHHHHHHHccTTcccHHHHHHcccTTcEEEcccTTTcccEEEcccccTTTTccEEEEEc##cTT#####ccEEEEEccTT##################### DISOP:02AL 1-2, 530-533| PSIPRED ccccEEEEEEcccccHHHcccccccHHHHHHHHHHHHHccccEEEEEEccccHHHHHHHHHHHHccccHHHHHHHHHHHHHccccHHHHHHHHHccccEEEEEccccHHHHHHHHcccHHHHHHHHHHHHHHHHHcccEEEEEEccccccccccHHHHHHHHHHHHHccccEEEEccccccccHHHHHHHHHHHHHHcccccEEEEEEccHHHHHHHHHHHHHHcccEEEEEccccccccccccHHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHHHHHcccccccccccccccEEEEccccHHHHHcccHHcccccHHHHcccEEEEEEcHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHcccccEEEEEEEEEEEEEccccccEEEEEEEEEEccEEEEEEEEccccHHHHHHHHHHHHHHHHcccccccEEEEEEEEEEEcccccEEEEEEEEEEEEcccEEEEEEEccHHHHHHHHHHHHHHHHHHHHHHHHHccc //