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Candidatus Pelagibacter ubique HTCC1062 (pubi0)
Gene : alaS
DDBJ      :alaS         alanine-tRNA ligase
Swiss-Prot:SYA_PELUB    RecName: Full=Alanyl-tRNA synthetase;         EC=6.1.1.7;AltName: Full=Alanine--tRNA ligase;         Short=AlaRS;

Homologs  Archaea  68/68 : Bacteria  907/915 : Eukaryota  195/199 : Viruses  0/175   --->[See Alignment]
a.203.1b.43.3d.104.1d.67.1
:889 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   7->432 1yfrA PDBj e-117 48.9 %
:BLT:PDB   564->689 1nyrB PDBj 6e-10 29.9 %
:RPS:PDB   6->432 2cvsA PDBj 2e-64 10.8 %
:RPS:PDB   453->705 2e1bA PDBj 6e-46 30.5 %
:RPS:PDB   678->889 3c9iF PDBj 5e-09 8.0 %
:RPS:SCOP  5->247 1riqA2  d.104.1.1 * e-116 56.8 %
:RPS:SCOP  248->462 1riqA1  a.203.1.1 * 6e-50 32.7 %
:RPS:SCOP  453->552 2e1bA1  b.43.3.6 * 6e-17 35.3 %
:RPS:SCOP  557->702 1v4pA  d.67.1.2 * 2e-35 23.6 %
:HMM:SCOP  3->247 1riqA2 d.104.1.1 * 1.4e-108 64.4 %
:HMM:SCOP  248->463 1riqA1 a.203.1.1 * 8.9e-62 39.5 %
:HMM:SCOP  552->727 1nyrA3 d.67.1.1 * 1e-47 46.7 %
:RPS:PFM   8->556 PF01411 * tRNA-synt_2c e-162 50.6 %
:RPS:PFM   653->700 PF07973 * tRNA_SAD 1e-08 53.5 %
:HMM:PFM   8->556 PF01411 * tRNA-synt_2c 1.8e-217 50.9 546/551  
:HMM:PFM   653->701 PF07973 * tRNA_SAD 6.2e-20 65.9 44/44  
:HMM:PFM   817->879 PF02272 * DHHA1 1.1e-12 37.3 59/68  
:HMM:PFM   535->590 PF01274 * Malate_synthase 0.00027 25.0 56/523  
:BLT:SWISS 1->889 SYA_PELUB 0.0 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAZ21463.1 GT:GENE alaS GT:PRODUCT alanine-tRNA ligase GT:DATABASE GIB00256CH01 GT:ORG pubi0 GB:ACCESSION GIB00256CH01 GB:LOCATION 628540..631209 GB:FROM 628540 GB:TO 631209 GB:DIRECTION + GB:GENE alaS GB:PRODUCT alanine-tRNA ligase GB:PROTEIN_ID AAZ21463.1 GB:DB_XREF GI:71062460 GB:GENE:GENE alaS LENGTH 889 SQ:AASEQ MADKTLNQIRTTFLDYFEKNDHKIVESSNLVPNNDPTLMFANSGMVQFKNIFTGLEKRDYVRATTSQKCVRAGGKHNDLENVGYTPRHHTFFEMLGNFSFGDYFKEEAISYAWNLITKEFGIDKNRLYVTVYHNDEEAFNFWKKIAGFSDDRIIKIATSDNFWSMGDTGPCGPCSEIFYDHGDHLEGGLPGTKNEDGNRFIEIWNLVFMQYEQISKDKRINLPKPSVDTGMGLERIAALLQGTHDNYETDHFKKLILSASDTLNVKVTDDNQSSFRVIADHLRASSFLLAEGVLPSNEGRGYVLRRIMRRGMRHSHLLGSKKPVFYNIFKTLLEEMSNNYPELERAQSLIKETLKTEEEKFLVLLDRGIKILNEELEKVEKILPGEVAFKLYDTFGFPLDLTEDILKNKSMTVDGEKFDLLMKESKKLAKKNWKGSGDSSVDQIWFDIKDRLGATDFLGYSTDKAEGVVTLILKNNKEVQDLQENDEGIIITNQTPFYGESGGQVADTGIISKEAFEFEVSDVQKKLGDLFVHYGKVKRGSVKLKDNVELKIDTQRRNNIRAYHSATHLLHEALRRVLGEHVTQKGSLVQSDRLRFDFSHMKPISDEEIRKIEHYVNSIIEKKSEVKTRIMTPKEAVENGALALFGEKYGDEVRVLSMGDEEGKFFSTELCGGTHVVNTADIGKFKIISQSSIAAGVRRVEALRDAQLIDFLKEKENQSNLSDQKNEAVIKELETKIIKLGGKPNLQNKDQVTLIKDLNRQFDQLSVISILKDKDKNKINDQTINGFKVRFQNIIDLPFKDLRKLIDEGKKEIGEGLVVIYAINDNKVGLAVGVTKTLEKKFDAVKIVRAGSEVIGGKGGGGRADFAQAGGTLPDKIEESFENIKKLIN GT:EXON 1|1-889:0| SW:ID SYA_PELUB SW:DE RecName: Full=Alanyl-tRNA synthetase; EC=6.1.1.7;AltName: Full=Alanine--tRNA ligase; Short=AlaRS; SW:GN Name=alaS; OrderedLocusNames=SAR11_0643; SW:KW Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm;Ligase; Metal-binding; Nucleotide-binding; Protein biosynthesis; Zinc;Zinc-finger. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->889|SYA_PELUB|0.0|100.0|889/889| GO:SWS:NREP 7 GO:SWS GO:0004812|"GO:aminoacyl-tRNA ligase activity"|Aminoacyl-tRNA synthetase| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006412|"GO:translation"|Protein biosynthesis| SEG 351->365|ketlkteeekflvll| SEG 768->785|isilkdkdknkindqtin| SEG 856->862|ggkgggg| BL:PDB:NREP 2 BL:PDB:REP 7->432|1yfrA|e-117|48.9|417/448| BL:PDB:REP 564->689|1nyrB|6e-10|29.9|117/637| RP:PDB:NREP 3 RP:PDB:REP 6->432|2cvsA|2e-64|10.8|415/657| RP:PDB:REP 453->705|2e1bA|6e-46|30.5|213/216| RP:PDB:REP 678->889|3c9iF|5e-09|8.0|201/221| RP:PFM:NREP 2 RP:PFM:REP 8->556|PF01411|e-162|50.6|541/546|tRNA-synt_2c| RP:PFM:REP 653->700|PF07973|1e-08|53.5|43/44|tRNA_SAD| HM:PFM:NREP 4 HM:PFM:REP 8->556|PF01411|1.8e-217|50.9|546/551|tRNA-synt_2c| HM:PFM:REP 653->701|PF07973|6.2e-20|65.9|44/44|tRNA_SAD| HM:PFM:REP 817->879|PF02272|1.1e-12|37.3|59/68|DHHA1| HM:PFM:REP 535->590|PF01274|0.00027|25.0|56/523|Malate_synthase| GO:PFM:NREP 11 GO:PFM GO:0000166|"GO:nucleotide binding"|PF01411|IPR018164| GO:PFM GO:0004813|"GO:alanine-tRNA ligase activity"|PF01411|IPR018164| GO:PFM GO:0005524|"GO:ATP binding"|PF01411|IPR018164| GO:PFM GO:0005737|"GO:cytoplasm"|PF01411|IPR018164| GO:PFM GO:0006412|"GO:translation"|PF01411|IPR018164| GO:PFM GO:0006419|"GO:alanyl-tRNA aminoacylation"|PF01411|IPR018164| GO:PFM GO:0005524|"GO:ATP binding"|PF07973|IPR012947| GO:PFM GO:0005737|"GO:cytoplasm"|PF07973|IPR012947| GO:PFM GO:0006412|"GO:translation"|PF07973|IPR012947| GO:PFM GO:0016876|"GO:ligase activity, forming aminoacyl-tRNA and related compounds"|PF07973|IPR012947| GO:PFM GO:0043039|"GO:tRNA aminoacylation"|PF07973|IPR012947| RP:SCP:NREP 4 RP:SCP:REP 5->247|1riqA2|e-116|56.8|234/236|d.104.1.1| RP:SCP:REP 248->462|1riqA1|6e-50|32.7|205/212|a.203.1.1| RP:SCP:REP 453->552|2e1bA1|6e-17|35.3|85/87|b.43.3.6| RP:SCP:REP 557->702|1v4pA|2e-35|23.6|144/151|d.67.1.2| HM:SCP:REP 3->247|1riqA2|1.4e-108|64.4|233/0|d.104.1.1|1/1|Class II aaRS and biotin synthetases| HM:SCP:REP 248->463|1riqA1|8.9e-62|39.5|215/0|a.203.1.1|1/1|Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)| HM:SCP:REP 552->727|1nyrA3|1e-47|46.7|169/179|d.67.1.1|1/1|ThrRS/AlaRS common domain| OP:NHOMO 1396 OP:NHOMOORG 1170 OP:PATTERN 11112121111111111211112121112211111111111111111122222121233322223111 1211111111111111111-1111111111111111111111111111111111111111111111112211-111111111211111111111121-111111111121111111111111111111111111111111111111111111111111111111112111111111111111111111111111222222221222221111111221111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112211111111111111111112111111111111121111111111111111111111111112111111111111111111111111111111111111111111111111112211111111111111111111111111111111111111-1111111111111111111111111211112111111111111111212111111111112111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111-111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111121212111111 1111241-31111111211-111111211111111111111111111111212222111111111111-2111111111111111111-12121111111111223123133332632221222242223F212222222221221222122223322122222332322322122222I2221223651212223222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 876 STR:RPRED 98.5 SQ:SECSTR ##cccHHHHHHHHHHHHHTcccEEEEcTTcccTTccccccccccHHHHHHHHHHHHHHccTTcTTHHHHHTTHcTcccccccccccccccEEETEEEEEcHHHHHHHHTTcEEEEcGGccHHHHHHHHHHHHHTEEEHHHHHHHHHHHHHHHcccHHHTcTTTTTcccccccTTccccccccTTEccccccccEEcHHHHHHHHHHHHHHHHHHHHHcccccHHHHcccEEEEEcHHHHHHHTTccTTcHHHHHHHHHHHHHHHHHHHHHHcTTcTTcGGGGTccTGGGGTccccccccHHHHHHHHHHHcccccccccccccTTHHHHTTcccccccccccEEcccEEcHHccHHHHHHHHHHTTcccHHHHHHHHHTTTcccHHHHHHTccTTcccHHHHHHHHHHHHTTccccccccEEcccccHHHHHTccccEEEEEEEEccGGGTcccccccTTccTTccEEEEcccEEETTEEEEEccccccccccccccccccTTcccccEEETTTTEEEEEEEEEcEcTTcccEEEEccGGGccccccEEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHTTccEEEEccccccEEEEEEEccccGGcGGHHHHHHHHHHHHHHcccEEEEEccccEEEEETTccccTTTcTTHHHHHTccccEEccccEEcccccccccGGGTccEEEEEEEEEETTEEEEEEEEcHHHHHHHHHHHHHHcccccEEEH######HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH#####HHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccccEEETTEEEEccccccccccccccccccccccTTHHHHHHHHHHHHHHH DISOP:02AL 1-4, 423-440| PSIPRED cccccHHHHHHHHHHHHHHcccEEcccccccccccccEEEEEcccccccccccccccccccccccccHHHHcccccccHHHcccccccHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHccccccEEEEEEcccHHHHHHHHHHccccHHHEEEccccccccccccccccccccEEEEEEccccccccccccccccccEEEEEEEEEEEEEEcccccEEEcccccccccccHHHHHHHHcccccccHHHHHHHHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHccHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccHHHHEEEEHHccccHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHcccccccccccccccEEEEEEEEcccEEEEEEcccEEEEEEEccccccccccccccEEEEEEccEEEEEEEEEEccccEEEEEEEEEccccccccEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHccccEEEEccEEccccEEEEEEccccccHHHHHHHHHHHHHHHHccccEEEEEEcHHHHHHHHHHHHcccccccEEEEEEEccccccEEEEEccccccccccccEEEEEEEEEEEccccEEEEEEEEcHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccEEEEEEEcccccHHHHHHHHHHHHHHccccEEEEEEEccccEEEEEEEcHHHHccccHHHHHHHHHHHHccccccccHHHcccccccHHHHHHHHHHHHHHHc //