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Candidatus Pelagibacter ubique HTCC1062 (pubi0)
Gene : dxs
DDBJ      :dxs          1-D-deoxyxylulose 5-phosphate synthase
Swiss-Prot:DXS_PELUB    RecName: Full=1-deoxy-D-xylulose-5-phosphate synthase;         EC=2.2.1.7;AltName: Full=1-deoxyxylulose-5-phosphate synthase;         Short=DXP synthase;         Short=DXPS;

Homologs  Archaea  39/68 : Bacteria  849/915 : Eukaryota  139/199 : Viruses  0/175   --->[See Alignment]
c.23.10c.36.1c.48.1
:637 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   7->625 2o1xB PDBj e-120 43.9 %
:RPS:PDB   24->636 1ay0A PDBj 6e-89 18.7 %
:RPS:SCOP  13->254 1um9A  c.36.1.11 * 5e-28 15.8 %
:RPS:SCOP  248->475 2apjA1  c.23.10.7 * 5e-45 14.7 %
:RPS:SCOP  484->636 1ay0A3  c.48.1.1 * 9e-21 13.9 %
:HMM:SCOP  1->380 1w85A_ c.36.1.11 * 4.1e-85 37.2 %
:HMM:SCOP  289->484 1qgdA1 c.36.1.6 * 3.5e-66 42.0 %
:HMM:SCOP  489->626 1dtwB2 c.48.1.2 * 1.5e-33 38.8 %
:RPS:PFM   27->299 PF00456 * Transketolase_N 2e-12 34.4 %
:RPS:PFM   319->477 PF02779 * Transket_pyr 7e-17 38.3 %
:RPS:PFM   499->584 PF02780 * Transketolase_C 6e-14 42.4 %
:HMM:PFM   319->479 PF02779 * Transket_pyr 6.8e-41 30.0 160/178  
:HMM:PFM   495->618 PF02780 * Transketolase_C 4.8e-32 35.0 123/124  
:HMM:PFM   240->300 PF00456 * Transketolase_N 7.5e-05 27.1 59/333  
:HMM:PFM   109->182 PF00676 * E1_dh 7.1e-09 29.2 72/300  
:HMM:PFM   12->36 PF12188 * STAT2_C 0.00039 32.0 25/56  
:BLT:SWISS 1->637 DXS_PELUB 0.0 100.0 %
:PROS 32->51|PS00801|TRANSKETOLASE_1

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAZ21432.1 GT:GENE dxs GT:PRODUCT 1-D-deoxyxylulose 5-phosphate synthase GT:DATABASE GIB00256CH01 GT:ORG pubi0 GB:ACCESSION GIB00256CH01 GB:LOCATION 596553..598466 GB:FROM 596553 GB:TO 598466 GB:DIRECTION + GB:GENE dxs GB:PRODUCT 1-D-deoxyxylulose 5-phosphate synthase GB:PROTEIN_ID AAZ21432.1 GB:DB_XREF GI:71062429 GB:GENE:GENE dxs LENGTH 637 SQ:AASEQ MQNYKFLKDINFPSDLRKLSENDLQEVSNEVRKEMIDAVSETGGHLGAGLGVVELTVALHYVFDTPNDRLIWDVGHQTYPHKILTGRKSKIKTLRQGNGLSGFTKRSESEYDPFGAAHSSTSISSALGMAEANKLSNKLNNIIAVIGDGAISAGMAYEAMNNAGASKTKMIVILNDNDMSIAKPVGAMRTYLAKLLTGKIYFSLRETFKLIVSAFSKRFSVKAGKAEDFLRSAVTGGTLFNSLGFYYVGPIDGHDLSTLIPILKNARDSKHQGPIMIHIKTQKGKGYSYAEKASDHYHGVSKFNVVTGEQVKSGTNLPAYTKVFANTLVKHAERDSKVVGVTAAMPGGTGMDIFAKDFPKRMFDVGIAEQHAVTFAAGLATEGYKPYVAIYSTFLQRAYDQVVHDVAIQSLPVRFIIDRAGLVGADGSTHAGSFDITYLSTLPNFIVMAPSDEAELVKMTNTSMTINNKPCAIRYPRGNGIGVELPSIDENIEIGKGRVIQEGKQVCILSIGTRLEECKIAAAELKNKGIESTIVDARFAKPLDQELILKCAREHEAMITVEEGSIGGFGSHVENLLSEKGIFDKGLKFRTMILPDIFIEQDSPKKMYDVAGLNASQISKKILDILFTKESIKVVKN GT:EXON 1|1-637:0| SW:ID DXS_PELUB SW:DE RecName: Full=1-deoxy-D-xylulose-5-phosphate synthase; EC=2.2.1.7;AltName: Full=1-deoxyxylulose-5-phosphate synthase; Short=DXP synthase; Short=DXPS; SW:GN Name=dxs; OrderedLocusNames=SAR11_0611; SW:KW Complete proteome; Isoprene biosynthesis; Thiamine biosynthesis;Thiamine pyrophosphate; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->637|DXS_PELUB|0.0|100.0|637/637| GO:SWS:NREP 3 GO:SWS GO:0008299|"GO:isoprenoid biosynthetic process"|Isoprene biosynthesis| GO:SWS GO:0009228|"GO:thiamin biosynthetic process"|Thiamine biosynthesis| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 32->51|PS00801|TRANSKETOLASE_1|PDOC00635| BL:PDB:NREP 1 BL:PDB:REP 7->625|2o1xB|e-120|43.9|565/579| RP:PDB:NREP 1 RP:PDB:REP 24->636|1ay0A|6e-89|18.7|595/678| RP:PFM:NREP 3 RP:PFM:REP 27->299|PF00456|2e-12|34.4|227/275|Transketolase_N| RP:PFM:REP 319->477|PF02779|7e-17|38.3|154/172|Transket_pyr| RP:PFM:REP 499->584|PF02780|6e-14|42.4|85/122|Transketolase_C| HM:PFM:NREP 5 HM:PFM:REP 319->479|PF02779|6.8e-41|30.0|160/178|Transket_pyr| HM:PFM:REP 495->618|PF02780|4.8e-32|35.0|123/124|Transketolase_C| HM:PFM:REP 240->300|PF00456|7.5e-05|27.1|59/333|Transketolase_N| HM:PFM:REP 109->182|PF00676|7.1e-09|29.2|72/300|E1_dh| HM:PFM:REP 12->36|PF12188|0.00039|32.0|25/56|STAT2_C| GO:PFM:NREP 2 GO:PFM GO:0003824|"GO:catalytic activity"|PF02780|IPR005476| GO:PFM GO:0008152|"GO:metabolic process"|PF02780|IPR005476| RP:SCP:NREP 3 RP:SCP:REP 13->254|1um9A|5e-28|15.8|228/331|c.36.1.11| RP:SCP:REP 248->475|2apjA1|5e-45|14.7|204/244|c.23.10.7| RP:SCP:REP 484->636|1ay0A3|9e-21|13.9|137/146|c.48.1.1| HM:SCP:REP 1->380|1w85A_|4.1e-85|37.2|320/0|c.36.1.11|1/1|Thiamin diphosphate-binding fold (THDP-binding)| HM:SCP:REP 289->484|1qgdA1|3.5e-66|42.0|188/195|c.36.1.6|1/1|Thiamin diphosphate-binding fold (THDP-binding)| HM:SCP:REP 489->626|1dtwB2|1.5e-33|38.8|134/138|c.48.1.2|1/1|TK C-terminal domain-like| OP:NHOMO 1997 OP:NHOMOORG 1027 OP:PATTERN 22-1--1132223231-112111------1-----11111111-----------11-1111112--11 122151111111-121122-2111232122211111246322332122111163311211213232544111111111522231112222231111112234443334262222222121222222212222223213311111132221223112222222222113311322123222122111111112222222222222222223333322213442122233322331222222222222221221-12--11-31-2222221-11---3222221122-11111111111111111111111111-11111222221225444444454624222222113--1252222322212224322434131111121121124443233323322222222223-443446433321433123334343251113214344412444444443442222211122111----11---111111111-1123472322121422122222223323222212113121111221211112122221121111121111111111111121211111131111344333334112121121112111111111111111111221221122213221124222223222222222231--31111--11121222311111111111-111111111111111111333321111322222222222222211111111112212222222221111-----11111121111122111111111122222111113111111122111221221111111111-11111111111111111111111111111132333344--------11------------1---1--1------1312223232211 22--22--621---11111-11-1-112211111---------111---12222111111111-1----1---11---------11-1----1--1-------211-14225731313-1234244272Ee4-644131142362-21124213-212311-1132-622B11413221T2222343891641211112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 637 STR:RPRED 100.0 SQ:SECSTR HHHHHTGcccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHTccTTccEEEEccGGGHHHHHHHTTcHHHHTTTTcTTccccccccTTcTTcccccccTTHHHHHHHHHHHHHHHHHHHHcEEEEEcHHHHHcHHHHHHHHHHHHTTcTTEEEEEEccEETTEEGGTccccHHHHHHHHTcEEEETcHHHHHHHHHHHTTcTTccEEEEEEccTTTTcTTTTcGGGTcccccHHHHHHHHHHTTccTTcccEccccHHHHHHHHHHTHHHHHHHHHHHHccTTGGGGcccccTTcccEEHHHHHHHHHHHHTTTcTTEEEEEcccHHHHTcGGccEETTccEEEccccHHHHHHHHHHHHHHcTTcEEEEEHHHHGGGHHHHHHHHHHTcccEEEEEcccGGGcTTcTTcccccHHHHHTcccccEEEccccHHHHHHHHHHHHHcccccEEEEccccEEcccTTccHHHHTTccEEEEccccccEEEEEcTTHHHHHHHHHHHHHHTTccEEEEEcccHHHHHTccHHHHHHTTccEEEEcccccGGGGGTccEEEccHcTTTcccccEEEEEcccccccccHHHHHHHHTccHHHHHHHHHHHHHHHTTcccccT DISOP:02AL 1-2, 633-634, 636-637| PSIPRED ccccccccccccHHHHHcccHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHcccccccEEEEEcccHHHHHHHHHccHHHHHHHHcccccccccccccccccEEccccHHHHHHHHHHHHHHHHHHccccEEEEEEEccccccHHHHHHHHHHHHHcccEEEEEEccccEEcccHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccHHHccccEEEccccccHHHHHHHHHHHHHccccccEEEEHHHHHHHHHHHHHHHHHHHHcccccHHHccccccccccHHHHHHHHHHHHHHHHHHcccEEEEEccccccccHHHHHHHccccEEEccHHHHHHHHHHHHHHHcccEEEEEHHHHHHHHHHHHHHHHHHHccccEEEEEEccccccccccccccHHHHHHHHHHcccEEEEEccHHHHHHHHHHHHHccccEEEEEEcccccccccccccccEEccccEEEEEccccEEEEEEcHHHHHHHHHHHHHHHccccEEEEcccccccccHHHHHHHHHHcccEEEEEccccccHHHHHHHHHHHcccccccccEEEEEEcccccccccHHHHHHHHcccHHHHHHHHHHHHccccccccccc //