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Candidatus Pelagibacter ubique HTCC1062 (pubi0)
Gene : hemH
DDBJ      :hemH         probable ferrochelatase
Swiss-Prot:HEMH_PELUB   RecName: Full=Ferrochelatase;         EC=4.99.1.1;AltName: Full=Protoheme ferro-lyase;AltName: Full=Heme synthetase;

Homologs  Archaea  4/68 : Bacteria  645/915 : Eukaryota  184/199 : Viruses  0/175   --->[See Alignment]
c.92.1
:344 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->317 2qd3A PDBj 4e-43 35.0 %
:RPS:PDB   2->312 2c8jB PDBj 2e-57 26.0 %
:RPS:SCOP  2->312 1ak1A  c.92.1.1 * 8e-66 25.0 %
:HMM:SCOP  1->317 1hrkA_ c.92.1.1 * 1.2e-88 39.2 %
:RPS:PFM   2->312 PF00762 * Ferrochelatase 5e-58 37.7 %
:HMM:PFM   2->314 PF00762 * Ferrochelatase 1.5e-109 42.7 309/316  
:BLT:SWISS 1->344 HEMH_PELUB 0.0 100.0 %
:PROS 186->204|PS00534|FERROCHELATASE

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAZ21168.1 GT:GENE hemH GT:PRODUCT probable ferrochelatase GT:DATABASE GIB00256CH01 GT:ORG pubi0 GB:ACCESSION GIB00256CH01 GB:LOCATION 336739..337773 GB:FROM 336739 GB:TO 337773 GB:DIRECTION + GB:GENE hemH GB:PRODUCT probable ferrochelatase GB:PROTEIN_ID AAZ21168.1 GB:DB_XREF GI:71062165 GB:GENE:GENE hemH LENGTH 344 SQ:AASEQ MKKAVILFNLGGPDKIENVEPFLFNLFNDPAILNLPTILRYPLAKLISNRRAPVAKKIYKELGGSSPILKLTMAQSKALETKLNQTEIDSEYKCFIVMRCWNPRANDVIKDVQSFNPEEIILMPLYPQYSAATSGSSIKEWRDVCKKNNYHVKTNTICCYPTDQNFINAHTKEIIKKIKDLKNFKLIFSAHGLPEKNIKKGDPYQWQVEQSVKKIVENLNIENLDWILSYQSRVGPLKWIGPSTEDIIVENSKLAKHIVLVPIAFVSEHSETLVELDIEYKEIADANGCKNYTRVPALGTNEDFIKAMSELIIKKNEYKFSENLYPPKIQCPSNFKKCPCLNYE GT:EXON 1|1-344:0| SW:ID HEMH_PELUB SW:DE RecName: Full=Ferrochelatase; EC=4.99.1.1;AltName: Full=Protoheme ferro-lyase;AltName: Full=Heme synthetase; SW:GN Name=hemH; OrderedLocusNames=SAR11_0346; SW:KW Complete proteome; Cytoplasm; Heme biosynthesis; Iron; Lyase;Metal-binding; Porphyrin biosynthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->344|HEMH_PELUB|0.0|100.0|344/344| GO:SWS:NREP 5 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006783|"GO:heme biosynthetic process"|Heme biosynthesis| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0006779|"GO:porphyrin biosynthetic process"|Porphyrin biosynthesis| PROS 186->204|PS00534|FERROCHELATASE|PDOC00462| BL:PDB:NREP 1 BL:PDB:REP 2->317|2qd3A|4e-43|35.0|311/359| RP:PDB:NREP 1 RP:PDB:REP 2->312|2c8jB|2e-57|26.0|292/310| RP:PFM:NREP 1 RP:PFM:REP 2->312|PF00762|5e-58|37.7|308/315|Ferrochelatase| HM:PFM:NREP 1 HM:PFM:REP 2->314|PF00762|1.5e-109|42.7|309/316|Ferrochelatase| GO:PFM:NREP 2 GO:PFM GO:0004325|"GO:ferrochelatase activity"|PF00762|IPR001015| GO:PFM GO:0006783|"GO:heme biosynthetic process"|PF00762|IPR001015| RP:SCP:NREP 1 RP:SCP:REP 2->312|1ak1A|8e-66|25.0|292/308|c.92.1.1| HM:SCP:REP 1->317|1hrkA_|1.2e-88|39.2|314/0|c.92.1.1|1/1|Chelatase| OP:NHOMO 922 OP:NHOMOORG 833 OP:PATTERN ---------------------------------------------------------1---111---- -11-1111-------------------------------------11--111-111--------1-----1--------111-11111------11---11111111121111111111111111--------------11---1131111111111111111111111111111111111111-111---111222222222222222112211221111111111111111111111111111111111111---11-----111111----1-111-------1111111111111--------------1--111--------------------------------1------------1--------1111111-----111111111111111111111111-111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111---1----------111111111111111--11-111111111111111111111111111111111111222211222222222221--11111------11-11111111111111-1111111111111111111-111111111111111111111111111111111111111111111--1111111111111111111111-111-1111111111111111111111111111111111111111111111111111111111111111111111111111111-1------------------------------------------------- 11--11--1---22111111111111111111111112111111111111111111111111111111-1111111111111111111-11111111111111111-14-21111111111111221112A2-2131111111111111111121221211-111113112--21111191111132241221121112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 317 STR:RPRED 92.2 SQ:SECSTR cEEEEEEEEccccccGGGHHHHHHHHTTTccccHHTccTHHHHHHcccHHHHHHHHHHHHHTTccTTGGGHHHHHHHHHHHHHHHHccccEEEEEEEEccccccHHHHHHHHHHHTccEEEEEEccccccHHHHHHTHHHHHHHHHHHccccEEEEccccTTcHHHHHHHHHHHHHHHTTHTTEEEEEEEEcccTHHHHHTccHHHHHHHHHHHHHHHTTcccEcEEEEEEccccccccccccHHHHHHHHHTcccEEEEEcTTcccccHHHHTTTTTHHHHHHHHHTccEEEcccccTTcHHHHHHHHHHHHHHTc########################### DISOP:02AL 315-328| PSIPRED ccEEEEEEEccccccHHHHHHHHHHHccccccccccHHHHHHHHHccccccHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHccccccEEEEEEEccccccHHHHHHHHHHccccEEEEEEcccHHHHHHHHHHHHHHHHHHHHcccccEEEEEccccccHHHHHHHHHHHHHHHHcccccEEEEEEccccHHHHHcccccHHHHHHHHHHHHHHcccccccEEEEEEEcccccccccccHHHHHHHHHHcccEEEEEcccHHHHHHHHHHHHHHHHHHHHHHccccEEEEcccccccHHHHHHHHHHHHHHccccccccccccccccccccccccccccc //