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Candidatus Pelagibacter ubique HTCC1062 (pubi0)
Gene : hisS
DDBJ      :hisS         Histidyl-tRNA synthetase
Swiss-Prot:SYH_PELUB    RecName: Full=Histidyl-tRNA synthetase;         EC=6.1.1.21;AltName: Full=Histidine--tRNA ligase;         Short=HisRS;

Homologs  Archaea  65/68 : Bacteria  368/915 : Eukaryota  191/199 : Viruses  0/175   --->[See Alignment]
c.51.1d.104.1
:465 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   40->460 1wu7B PDBj 4e-26 31.6 %
:RPS:PDB   11->465 1adjA PDBj 3e-25 17.8 %
:RPS:SCOP  32->352 1usyA  d.104.1.1 * 3e-34 14.6 %
:RPS:SCOP  370->465 1v95A  c.51.1.1 * 4e-13 11.7 %
:HMM:SCOP  8->365 1kmmA2 d.104.1.1 * 2.8e-53 28.4 %
:HMM:SCOP  365->466 1adjA1 c.51.1.1 * 3.3e-17 32.3 %
:RPS:PFM   37->153 PF00587 * tRNA-synt_2b 9e-11 37.6 %
:RPS:PFM   369->462 PF03129 * HGTP_anticodon 7e-08 32.6 %
:HMM:PFM   25->173 PF00587 * tRNA-synt_2b 8e-18 26.9 145/173  
:HMM:PFM   370->463 PF03129 * HGTP_anticodon 1e-14 24.7 89/94  
:HMM:PFM   168->224 PF09077 * Phage-MuB_C 0.00027 25.9 54/78  
:BLT:SWISS 1->465 SYH_PELUB 0.0 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAZ21300.1 GT:GENE hisS GT:PRODUCT Histidyl-tRNA synthetase GT:DATABASE GIB00256CH01 GT:ORG pubi0 GB:ACCESSION GIB00256CH01 GB:LOCATION 467248..468645 GB:FROM 467248 GB:TO 468645 GB:DIRECTION + GB:GENE hisS GB:PRODUCT Histidyl-tRNA synthetase GB:PROTEIN_ID AAZ21300.1 GB:DB_XREF GI:71062297 GB:GENE:GENE hisS LENGTH 465 SQ:AASEQ MNKENKLIPGLPSGFEDRWGKKLILKKKLINTIEANFVKFGFGALETPSFEISENIGSFLADDDSNPMSDVFSFKDGEKNITLRYDLSSPLARFVAQNNQELPLPYKRYQMGDVWRNEKAGNARYRSFLQCDADIVGNVNPAQANAELCNLIASTLLACGLKKDQFVVNISNRKIVQGLIEDLKISDDKKIKVMRAIDKLDKPGFGLRGVEDLLKEERVDASGAVTKGANLTDDQASQIINFLKVKDLKELKENLKNPLSQEGIKELEDLLEIVSYGDYLDQIKTNFTIVRGLAYYDGFCVETNLNFKAKNSKGKEVDIGSICSGGQYNKLISRFKGVDIPGTGMSFGVDRLLFAMMQLDQIEVDEKKPVIICVMDEKYLKNYYEILKVLRDNNINSEIFLDSKKNLGKQLTYANKKQCPVAVICGENEFKDNTITLKNLLGVKGENNQLTFPKENLINEIKKFI GT:EXON 1|1-465:0| SW:ID SYH_PELUB SW:DE RecName: Full=Histidyl-tRNA synthetase; EC=6.1.1.21;AltName: Full=Histidine--tRNA ligase; Short=HisRS; SW:GN Name=hisS; OrderedLocusNames=SAR11_0478; SW:KW Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm;Ligase; Nucleotide-binding; Protein biosynthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->465|SYH_PELUB|0.0|100.0|465/465| GO:SWS:NREP 6 GO:SWS GO:0004812|"GO:aminoacyl-tRNA ligase activity"|Aminoacyl-tRNA synthetase| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006412|"GO:translation"|Protein biosynthesis| SEG 21->30|kklilkkkli| SEG 243->259|lkvkdlkelkenlknpl| BL:PDB:NREP 1 BL:PDB:REP 40->460|1wu7B|4e-26|31.6|373/407| RP:PDB:NREP 1 RP:PDB:REP 11->465|1adjA|3e-25|17.8|411/420| RP:PFM:NREP 2 RP:PFM:REP 37->153|PF00587|9e-11|37.6|109/170|tRNA-synt_2b| RP:PFM:REP 369->462|PF03129|7e-08|32.6|89/91|HGTP_anticodon| HM:PFM:NREP 3 HM:PFM:REP 25->173|PF00587|8e-18|26.9|145/173|tRNA-synt_2b| HM:PFM:REP 370->463|PF03129|1e-14|24.7|89/94|HGTP_anticodon| HM:PFM:REP 168->224|PF09077|0.00027|25.9|54/78|Phage-MuB_C| GO:PFM:NREP 9 GO:PFM GO:0000166|"GO:nucleotide binding"|PF00587|IPR002314| GO:PFM GO:0004812|"GO:aminoacyl-tRNA ligase activity"|PF00587|IPR002314| GO:PFM GO:0005524|"GO:ATP binding"|PF00587|IPR002314| GO:PFM GO:0005737|"GO:cytoplasm"|PF00587|IPR002314| GO:PFM GO:0006412|"GO:translation"|PF00587|IPR002314| GO:PFM GO:0006418|"GO:tRNA aminoacylation for protein translation"|PF00587|IPR002314| GO:PFM GO:0004812|"GO:aminoacyl-tRNA ligase activity"|PF03129|IPR004154| GO:PFM GO:0005524|"GO:ATP binding"|PF03129|IPR004154| GO:PFM GO:0006412|"GO:translation"|PF03129|IPR004154| RP:SCP:NREP 2 RP:SCP:REP 32->352|1usyA|3e-34|14.6|261/275|d.104.1.1| RP:SCP:REP 370->465|1v95A|4e-13|11.7|94/130|c.51.1.1| HM:SCP:REP 8->365|1kmmA2|2.8e-53|28.4|320/322|d.104.1.1|1/1|Class II aaRS and biotin synthetases| HM:SCP:REP 365->466|1adjA1|3.3e-17|32.3|96/96|c.51.1.1|1/1|Class II aaRS ABD-related| OP:NHOMO 837 OP:NHOMOORG 624 OP:PATTERN 1111111111111111111111111111-11111111111111-1111111111111111111111-1 ---1------------------------------------111111111111111111111111-1----11111111---1------111111111--111111111-1--------------1-----------11112---111--1----------------11112---1-----11--------11-12222222313332233111-13321------111111211---------------11111-1-11--1----2211----11111----1--111--------------------11--1--111---1121122221-1111121111---112111222-111-1-2-1-2121111111111111111111111111111111111111111-111111111111111111111111111111111111111--------------1-----1----------------------1-11-1----------------------------------------------------1---1---1----1-------1------1--------1--11----------1-1-11-----111111111111-----11---------1111111--------------------1----1------------------------------------------------------------------------------------1------------1--111---1--111--1--11------------------------------------1111111111-111111111111111111111111111111111111-1--11-1---------------11--1111-1-1-111 1111111-311111111121111111111-111111111111111111111211221211111111111111111111111-111111-12111111111111222112122112152222-3222212EV2-26E222232222123212222231331331121-221412111-21N2111212422222222211 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 465 STR:RPRED 100.0 SQ:SECSTR ccHHHHHHTHccTTcccccHHHHHHHHHHHHHHHHHHHHTTcEEcccccEEEHHHHHHHHcTTHHHHHcccEEEcTTccEEEEccccHHHHHHHHHHTTGGccccEEEEEEEEEEcccccccccccEEEEEEEEEEcccccHHHHHHHHHHHHHHHHHTTccccccEEEEEEcccHHHHHHHHHHHHHHHGGGGGGccHHHHHccGGGGTTcccHHHHHHHHHHTcccGGGGcccccccccHHHHHHHHHHHHTGGGcccHHHHHHHHHHGcTTcHHHHHHTTccEEEcccccccccccccEEEEEEHHHHHccccccccEEEEEEEcTTHHHHTTcccccEEEEEEEHHHHHHHHHHTTccccccccccEEEEEccHHHHHHHHHHHHHHTTTccEEEcccccccHHHHHHHHHHTTccEEEEEcHHHHHHTEEEEEETcccGTTccEEEEETTHHHHHHHHHH DISOP:02AL 1-6, 121-122| PSIPRED ccccccccccccccccccccHHHHHHHHHHHHHHHHHHHcccEEcccccccHHHHHHHHccccccccccEEEEEEccccEEEEcccccHHHHHHHHHHcccccccEEEEEEEEEEEccccccccccEEEEEEEEEEcccccHHHHHHHHHHHHHHHHHHcccccEEEEEEccHHHHHHHHHHHcccHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccEEEEccHHHcccHHHccEEEEEEEcccccccccccccccEEEEccccHHHHHHHccccccEEEEEccHHHHHHHHHHHcccccccccEEEEEEccHHHHHHHHHHHHHHHHccccEEEEEcccccHHHHHHHHHHccccEEEEEcHHHHHccEEEEEEEcccccccEEEEEcHHHHHHHHHHHc //