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Candidatus Pelagibacter ubique HTCC1062 (pubi0)
Gene : ilvD
DDBJ      :ilvD         dihydroxy-acid dehydratase
Swiss-Prot:ILVD_PELUB   RecName: Full=Dihydroxy-acid dehydratase;         Short=DAD;         EC=4.2.1.9;

Homologs  Archaea  54/68 : Bacteria  742/915 : Eukaryota  117/199 : Viruses  0/175   --->[See Alignment]
c.8.2d.334.1
:572 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   86->526 2gp4A PDBj 8e-21 28.3 %
:RPS:PDB   30->294 2cwlB PDBj 2e-35 9.3 %
:RPS:PDB   342->503 3ejfA PDBj 7e-21 10.5 %
:RPS:SCOP  53->380 2gp4A2  d.334.1.1 * 3e-81 29.7 %
:RPS:SCOP  381->561 2gp4A1  c.8.2.2 * 5e-28 24.3 %
:HMM:SCOP  1->380 2gp4A2 d.334.1.1 * 3.3e-133 46.0 %
:HMM:SCOP  381->566 2gp4A1 c.8.2.2 * 3.5e-53 45.9 %
:RPS:PFM   39->556 PF00920 * ILVD_EDD e-146 48.5 %
:HMM:PFM   39->556 PF00920 * ILVD_EDD 4.5e-214 50.8 518/521  
:BLT:SWISS 1->572 ILVD_PELUB 0.0 100.0 %
:PROS 127->137|PS00886|ILVD_EDD_1
:PROS 467->478|PS00887|ILVD_EDD_2
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAZ21769.1 GT:GENE ilvD GT:PRODUCT dihydroxy-acid dehydratase GT:DATABASE GIB00256CH01 GT:ORG pubi0 GB:ACCESSION GIB00256CH01 GB:LOCATION 945366..947084 GB:FROM 945366 GB:TO 947084 GB:DIRECTION + GB:GENE ilvD GB:PRODUCT dihydroxy-acid dehydratase GB:PROTEIN_ID AAZ21769.1 GB:DB_XREF GI:71062766 GB:GENE:GENE ilvD LENGTH 572 SQ:AASEQ MAKFNKKKLPSRHTSLGADRAPHRSFYYAMGETEKDVAKPFVGVVSTWNEAAPCNIALMRQAQSVKKGVRASGGTPREFCTITVTDGIAMGHEGMKSSLISREVIADSTELTVRGHCYDALVGIAGCDKSLPALMMAMVRLNVPSVFIYGGSILPGQYKGKDVTVVDVFEAVGKHSAGKMSAKELRKLELVACPSAGACGGQFTANTMACVSEAIGLALPYSAGTPAPYEERDKYALLSGKTVMNLLQKNIRPRDIVTKKSLENAATIVAATGGSTNAALHLPAIANEIGIKFDLMDVAKIFKKTPYLADLKPGGKYVAKDMWLAGGVPMLLKTLFDGGFIHGDCMTVTGKTMKQNLKNIKFNPKQKVLRAYDNPLSPDGGVVGLKGNLAPDGGIVKIAGLKKLQFTGKARCFDNEEAAMACVQKKKYKAGDVIIIRYEGPVGGPGMREMLSTTGAIYGQGMGEKVALITDGRFSGATRGFCVGHVGPEAALGGPLALLRNGDVIDIDAKKGTINVRLTKSQLATRHKKWKAKKSSFGSGTIWKYAQTVGPAYLGAPTHPGKRKEVKVYADI GT:EXON 1|1-572:0| SW:ID ILVD_PELUB SW:DE RecName: Full=Dihydroxy-acid dehydratase; Short=DAD; EC=4.2.1.9; SW:GN Name=ilvD; OrderedLocusNames=SAR11_0961; SW:KW 4Fe-4S; Amino-acid biosynthesis;Branched-chain amino acid biosynthesis; Complete proteome; Iron;Iron-sulfur; Lyase; Metal-binding. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->572|ILVD_PELUB|0.0|100.0|572/572| GO:SWS:NREP 6 GO:SWS GO:0051539|"GO:4 iron, 4 sulfur cluster binding"|4Fe-4S| GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0009082|"GO:branched chain family amino acid biosynthetic process"|Branched-chain amino acid biosynthesis| GO:SWS GO:0051536|"GO:iron-sulfur cluster binding"|Iron-sulfur| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| PROS 127->137|PS00886|ILVD_EDD_1|PDOC00690| PROS 467->478|PS00887|ILVD_EDD_2|PDOC00690| SEG 487->499|gpeaalggplall| BL:PDB:NREP 1 BL:PDB:REP 86->526|2gp4A|8e-21|28.3|396/509| RP:PDB:NREP 2 RP:PDB:REP 30->294|2cwlB|2e-35|9.3|237/298| RP:PDB:REP 342->503|3ejfA|7e-21|10.5|143/166| RP:PFM:NREP 1 RP:PFM:REP 39->556|PF00920|e-146|48.5|518/521|ILVD_EDD| HM:PFM:NREP 1 HM:PFM:REP 39->556|PF00920|4.5e-214|50.8|518/521|ILVD_EDD| GO:PFM:NREP 2 GO:PFM GO:0003824|"GO:catalytic activity"|PF00920|IPR000581| GO:PFM GO:0008152|"GO:metabolic process"|PF00920|IPR000581| RP:SCP:NREP 2 RP:SCP:REP 53->380|2gp4A2|3e-81|29.7|286/332|d.334.1.1| RP:SCP:REP 381->561|2gp4A1|5e-28|24.3|177/190|c.8.2.2| HM:SCP:REP 1->380|2gp4A2|3.3e-133|46.0|374/0|d.334.1.1|1/1|IlvD/EDD N-terminal domain-like| HM:SCP:REP 381->566|2gp4A1|3.5e-53|45.9|183/0|c.8.2.2|1/1|LeuD/IlvD-like| OP:NHOMO 1758 OP:NHOMOORG 913 OP:PATTERN 11-1--1111111111-11111111--11211111111111111111111211111-----1--1-11 2131211211111121111-121114111111211133332113242-211123111111121-23423211111111-11-111111111112---11--211211212---------------11111111111111111111111111111111111111111121111111111111111111111-11111111111111111121111111111111--1111111211111111111111111112---------------------1-111-------11111111111111-------------111222111-14-23111111111121112---2-1--1211122111111111111--12135444-22-2526771134543333333333225-33433537851-5554536666775522233423444342122222251122111-----------------------------2226222552746656452222557A222223447664512552325336463982211222212232222111311-2212111111111-1111111111111-3111111111112111111111111111222243323-2322322322233332222322-1-121111111122212314222422222-2232222222233223222222211123232323333323222322222221-22222222222211-------111122246111111-111111114444423111422222223322224333311-1-11-1121312222222123222222222222221111111111--------------------------------------1--1-111131 ------1-------134224464575622222222222222222222234334424333222111111111111111-1121111111-22242222222112222--4----------------------------------------------------------------1-1111I1111111342121132332 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 526 STR:RPRED 92.0 SQ:SECSTR ##########################ccccccccccccccccccc###cccccccHHHHHHHGGGTTcTTcHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHcccTTcccHHcccccGGGcTTGGGGcccccHHHHTcccccccccTTcccccGGGccccccHHHHHHHHHHHHHHHHHHHHHHHTTcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccGGGGcccccccGGGcHHHHHTTEEEHHHTTTTcEEEEccccccTTGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTcGGHHHHHHHHHHHTcHTTcGGGcHHHHHHHHHHHTccccccccccccccTTcccccHHHcccccHHHHHHHHHHcHHHHHHHHHHHHHHHHHccccEEEEccccTTEEEEEEEccccTTcccHHHHHHHHHHHHHHHHHTTccTTccEEEEEcccTTcTTccHHHHHHHHHHHHTTccEEEcccGGGcHHHHTEEcccccccEEccHHHHHHHHHHHHTTccEEEEccGG################# DISOP:02AL 1-14, 566-567, 569-572| PSIPRED cccccccccccHHHcccccHHHHHHHHHcccccHHHHcccEEEEEEcccccccccccHHHHHHHHHHHHHHccccEEEEcccccccccccccccccHHHHHHHHHHHHHHHHHcccccccEEEEcccccHHHHHHHHHHHccccEEEEEccccccccccccEEEEEEHHHHHHHHHcccccHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHHHHcccccHHHccHHHHHHHHHHHHHHcccHHHHHHHHHHHHHccccccHHHHHHHHHcccEEEEEccccHHHHHHHHHcccHHHHHHHHHHcccccccccccccccHHHHHHcccccccccccccHHHcccccccEEEEEcccccccEEEEEEccccEEEEEEEEEEccHHHHHHHHHccccccccEEEEEccccccccccHHHccccHHHHHcccccEEcEEEcccccccccccEEEEccHHHHccccEEEEEcccEEEEEccccEEEEEccHHHHHHHHHHccccccccccHHHHHHHHHHcHHHHcccccccccccccEEEcc //