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Rickettsia conorii str. Malish 7 (rcon0)
Gene : alaS
DDBJ      :alaS         alanyl-tRNA synthetase
Swiss-Prot:SYA_RICCN    RecName: Full=Alanyl-tRNA synthetase;         EC=6.1.1.7;AltName: Full=Alanine--tRNA ligase;         Short=AlaRS;

Homologs  Archaea  68/68 : Bacteria  907/915 : Eukaryota  195/199 : Viruses  0/175   --->[See Alignment]
a.203.1b.43.3d.104.1d.67.1
:878 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   5->433 1yfrA PDBj e-118 48.8 %
:BLT:PDB   493->699 2e1bA PDBj 7e-08 28.0 %
:RPS:PDB   8->433 2cvsA PDBj 5e-56 9.1 %
:RPS:PDB   455->700 2e1bA PDBj 1e-43 31.4 %
:RPS:PDB   677->828 3c9iF PDBj 2e-10 8.6 %
:RPS:SCOP  4->247 1riqA2  d.104.1.1 * e-118 52.3 %
:RPS:SCOP  248->463 1riqA1  a.203.1.1 * 1e-54 38.3 %
:RPS:SCOP  455->555 2e1bA1  b.43.3.6 * 1e-12 28.2 %
:RPS:SCOP  560->701 1v4pA  d.67.1.2 * 1e-37 23.2 %
:HMM:SCOP  3->247 1riqA2 d.104.1.1 * 6.9e-105 60.5 %
:HMM:SCOP  248->465 1riqA1 a.203.1.1 * 4e-65 42.9 %
:HMM:SCOP  555->726 1nyrA3 d.67.1.1 * 1.3e-50 43.2 %
:RPS:PFM   8->556 PF01411 * tRNA-synt_2c e-163 51.9 %
:RPS:PFM   656->698 PF07973 * tRNA_SAD 9e-10 55.8 %
:HMM:PFM   8->557 PF01411 * tRNA-synt_2c 1.2e-227 51.8 546/551  
:HMM:PFM   656->699 PF07973 * tRNA_SAD 3.8e-23 65.9 44/44  
:HMM:PFM   804->870 PF02272 * DHHA1 3.3e-10 33.3 63/68  
:HMM:PFM   686->774 PF10265 * DUF2217 0.00061 20.9 86/515  
:BLT:SWISS 1->878 SYA_RICCN 0.0 100.0 %
:PROS 600->612|PS00018|EF_HAND_1
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAL03865.1 GT:GENE alaS GT:PRODUCT alanyl-tRNA synthetase GT:DATABASE GIB00062CH01 GT:ORG rcon0 GB:ACCESSION GIB00062CH01 GB:LOCATION 1228334..1230970 GB:FROM 1228334 GB:TO 1230970 GB:DIRECTION + GB:GENE alaS GB:PRODUCT alanyl-tRNA synthetase GB:PROTEIN_ID AAL03865.1 GB:DB_XREF GI:15620469 GB:GENE:GENE alaS LENGTH 878 SQ:AASEQ MTKFTTEEVRSKFITYFKANNHTHVPASSLIPHNDPSLMFVNSGMVQFKNVFTGQGKRPYNKAVTSQKSLRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKEQAIYYAWNLLTKEFELPKDKLYATIYHTDDEAAAYWKKIAGFGDDRIIKIKTNDNFWSMGDTGPCGPCSEIFYDHGEQIYGGLPGTKDEDGDRFIEIWNMVFMQYEQIDKDTSIELSQKSIDTGMGLERMTAVLQHVNNNYDIDLFQEIINFTENIVKVKVEGEAKFSYRVIADHLRASSFLIADGVIPSNEGRGYVLRRIMRRSMRHAHMLGSKEPLMYKLLPKLVDLMGNVYPELKRAESFISSILEQEEIRFKATLERGLKLLTEETETLTKGNELSGEVAFKLYDTYGFPLDLTEDILKNRDIAVDHKGFEEQMLMQKARARKSWLGSGESKTDQLWFDIKEQHGSTEFLGYTLNEAKCKIIALIKNNNLVNDIKEIDTQFLLISNQTPFYGESGGQIGDIGTIFAKDSEVEVIDTLKYLGSIIIHKCILKKGQINVGENANFSIDIRYRQNLRIHHSATHILHAVLHEVLGKHVTQKGSLVAPTYLRFDISHSKAVTNEEITLIEDKVNEIIRDNHEVTTTLMATEDAIKQGAMALFGEKYDSEVRVVKMGETSLELCGGTHVRRTGDIGCFKITSESAIAAGVRRIEAVCGEFVITLMREKDSLLKSIESSFKTNKNELITKVNNILERNKEVEKELEKTLLASLDLSIEQIEKQSAQITGIKLLYKKVGNIDNKILRQAAENLTKKVEDLIMVYIAEGIGKLSITVAVSKAITDKYNADIIAKKLSLFLGGSGGGGQASLAQAGGNDIGKLTNIHEKLYSLLTVS GT:EXON 1|1-878:0| SW:ID SYA_RICCN SW:DE RecName: Full=Alanyl-tRNA synthetase; EC=6.1.1.7;AltName: Full=Alanine--tRNA ligase; Short=AlaRS; SW:GN Name=alaS; OrderedLocusNames=RC1327; SW:KW Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm;Ligase; Nucleotide-binding; Protein biosynthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->878|SYA_RICCN|0.0|100.0|878/878| GO:SWS:NREP 6 GO:SWS GO:0004812|"GO:aminoacyl-tRNA ligase activity"|Aminoacyl-tRNA synthetase| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006412|"GO:translation"|Protein biosynthesis| PROS 600->612|PS00018|EF_HAND_1|PDOC00018| SEG 364->385|tlerglkllteetetltkgnel| SEG 743->754|kevekelektll| SEG 842->858|lggsggggqaslaqagg| BL:PDB:NREP 2 BL:PDB:REP 5->433|1yfrA|e-118|48.8|420/448| BL:PDB:REP 493->699|2e1bA|7e-08|28.0|182/216| RP:PDB:NREP 3 RP:PDB:REP 8->433|2cvsA|5e-56|9.1|418/657| RP:PDB:REP 455->700|2e1bA|1e-43|31.4|207/216| RP:PDB:REP 677->828|3c9iF|2e-10|8.6|151/221| RP:PFM:NREP 2 RP:PFM:REP 8->556|PF01411|e-163|51.9|539/546|tRNA-synt_2c| RP:PFM:REP 656->698|PF07973|9e-10|55.8|43/44|tRNA_SAD| HM:PFM:NREP 4 HM:PFM:REP 8->557|PF01411|1.2e-227|51.8|546/551|tRNA-synt_2c| HM:PFM:REP 656->699|PF07973|3.8e-23|65.9|44/44|tRNA_SAD| HM:PFM:REP 804->870|PF02272|3.3e-10|33.3|63/68|DHHA1| HM:PFM:REP 686->774|PF10265|0.00061|20.9|86/515|DUF2217| GO:PFM:NREP 11 GO:PFM GO:0000166|"GO:nucleotide binding"|PF01411|IPR018164| GO:PFM GO:0004813|"GO:alanine-tRNA ligase activity"|PF01411|IPR018164| GO:PFM GO:0005524|"GO:ATP binding"|PF01411|IPR018164| GO:PFM GO:0005737|"GO:cytoplasm"|PF01411|IPR018164| GO:PFM GO:0006412|"GO:translation"|PF01411|IPR018164| GO:PFM GO:0006419|"GO:alanyl-tRNA aminoacylation"|PF01411|IPR018164| GO:PFM GO:0005524|"GO:ATP binding"|PF07973|IPR012947| GO:PFM GO:0005737|"GO:cytoplasm"|PF07973|IPR012947| GO:PFM GO:0006412|"GO:translation"|PF07973|IPR012947| GO:PFM GO:0016876|"GO:ligase activity, forming aminoacyl-tRNA and related compounds"|PF07973|IPR012947| GO:PFM GO:0043039|"GO:tRNA aminoacylation"|PF07973|IPR012947| RP:SCP:NREP 4 RP:SCP:REP 4->247|1riqA2|e-118|52.3|235/236|d.104.1.1| RP:SCP:REP 248->463|1riqA1|1e-54|38.3|206/212|a.203.1.1| RP:SCP:REP 455->555|2e1bA1|1e-12|28.2|85/87|b.43.3.6| RP:SCP:REP 560->701|1v4pA|1e-37|23.2|142/151|d.67.1.2| HM:SCP:REP 3->247|1riqA2|6.9e-105|60.5|233/0|d.104.1.1|1/1|Class II aaRS and biotin synthetases| HM:SCP:REP 248->465|1riqA1|4e-65|42.9|217/0|a.203.1.1|1/1|Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)| HM:SCP:REP 555->726|1nyrA3|1.3e-50|43.2|169/179|d.67.1.1|1/1|ThrRS/AlaRS common domain| OP:NHOMO 1477 OP:NHOMOORG 1170 OP:PATTERN 11112221222222111211122111112211111111111111111122222121233332223111 2211111111111111111-1111111111111111111111111111111111111111111111112211-111111111111111111211111-111111111121111111111111111111111111111111111111111111111111111111112111111111111111111111221111333332332333332112211332111211211111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122221111111212111111112111111211111221111111111211111111111111111111111111111111111111111111111211222122211221111112111111111111111111111111111111111111111-1111111111111111111111111211222111112221111111222221111111111111111111121111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111-111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111112222222212111 1111241-31111111121-111111211111111111111111111111112111111111111111-3212112211221111111-12111111111111222134134732633221223562223F212222222322421222142223322133222332422322122222I2221322441212223222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 817 STR:RPRED 93.1 SQ:SECSTR ##TTTcEHHHHHHHHHHHTcccEEEEcTTcccTTccccccccccHHHHHHHHHHHHHHcccEEETHHHHHTTHcTcccccccccccccccEEETEEEEEcHHHHHHHHTTcEEEEGGGccHHHHHHHHHHHHcEEEEHHHHHHHHHHHHHHHcccEEEEcTTTTTcccccccTTccccccccTEEccccccccEEcHHHHHHHHHHHHHHHHHHHHHcccHHHHHHcccEEEEEcHHHHHHHTTccTTcHHHHHHHHHHHHHHHHHHHHcccTTcTTcGGGGTccTGGGGTccccccccHHHHHHHHHHHcccccccccccccTTHHHHTTcccccccccccEEcccEEcHHHcHHHHHHTTcccHHHHHHHHHTTTccTTcTTccHHHHHHTccTTcccHHHHHHHHHHHHTTccccccccccHHHHHHHHHTTccccEEEEEEEEccGGGTcccccccTTTccEEEEccccccccc########EETTEEccccccccccccTTcccccEEEEETTTTEEEEEEEccTTcccEEEEEccGGGccccccEEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHTTccEEEEccccccEEEEEEEccccGGcGGHHHHHHHHHHHHHHcccEEEccccccccccEEcccccTTEEccccEEEEETTccEEcccccccccGGGTccEEEEEEEEEETTEEEEEETHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH#HHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccccc################################################## DISOP:02AL 1-4, 374-383, 427-441| PSIPRED cccccHHHHHHHHHHHHHHcccEEcccccccccccccEEEEEccccccccccccccccccccccccHHHHHcccccccHHHcccccccHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHcccHHEEEEEEEcccHHHHHHHHHHccccHHHEEEccccccccccccccccccccEEEEEcccccccccccccccccccEEEEEEEEEEEEEEcccccccccccccccccccHHHHHHHHccccccHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHccccHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHccccccccccEEEEccEEEEEEEEcccEEEEEEccccEEEEEEEccccccccccccccEEEEEEcccEEEEEEEEEEcccEEEEEEEEcccccccccEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHccccEEEcccEEcccEEEEEEcccccccHHHHHHHHHHHHHHHHccccEEEEEEcHHHHHHcccHHHccccccccEEEEEEccEEEEccccccccccccEEEEEEEEEEcccccEEEEEEEccHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccEEEEEEEcccccHHHHHHHHHHHHHHcccEEEEEEEEccccEEEEEEccHHHcccccHHHHHHHHHHHcccccccccHHHcccccccHHHHHHHHHHHHHHHHcc //